ライフサイエンスコーパス: glucocorticoid receptor

1 model with podocyte-specific deletion of the glucocorticoid receptor.

2 prednisolone by increasing the levels of the glucocorticoid receptor.

3 amethasone, induced nuclear migration of the glucocorticoid receptor.

4 hin the regulated genes, among which was the glucocorticoid receptor.

5 glomeruli through their interaction with the glucocorticoid receptor.

6 plication, implicating a membrane-associated glucocorticoid receptor.

7 ed to a significant elevation of hippocampal glucocorticoid receptors.

8 Glucocorticoids activate the glucocorticoid receptor, a ubiquitous nuclear receptor t

9 receptors (activated by epinephrine) and the glucocorticoid receptor (activated by corticosterone).

10 nd cocaine CPP in behaving rats both require glucocorticoid receptor activation during defeat episode

11 gulation of GILZ was neither associated with glucocorticoid receptor activation nor with transcriptio

12 ts as a co-chaperone that modulates not only glucocorticoid receptor activity in response to stressor

13 Inhibition of glucocorticoid receptors after neonatal insult blocked t

14 reatment with inhalation of the nonsteroidal glucocorticoid receptor agonist AZD5423 effectively redu

15 suggest that exogenous administration of the glucocorticoid receptor agonist dexamethasone-compared w

16 a (n = 297) before and after exposure to the glucocorticoid receptor agonist dexamethasone.

17 luated the effect of an inhaled nonsteroidal glucocorticoid receptor agonist, AZD5423, on allergen-in

18 We found that a synthetic glucocorticoid receptor agonist, dexamethasone, reduces

19 enanthrene-2,3,7-triol series of dissociated glucocorticoid receptor agonists (DAGRs) was achieved by

20 A-binding proteins, including CTCF, JunD and glucocorticoid receptor alpha (GRalpha), that show diffe

21 in like growth factor receptor 1 (Igf1), and glucocorticoid receptor alpha (Nr3c1) correlated with in

22 1 expression (rho=0.46, P<.02) and baseline glucocorticoid receptor alpha expression (rho=0.44, P<.0

23 ression, raised glucocorticoid receptor beta/glucocorticoid receptor alpha ratio, and high levels of

24 rthermore, the glomerular phosphorylation of glucocorticoid receptor and Akt, but not PPARgamma, corr

25 ith the key orexigenic transcription factors glucocorticoid receptor and brain-specific homeobox fact

26 t signaling through heterologously expressed glucocorticoid receptor and degradation of a permanently

27 nflammasome modulates cellular levels of the glucocorticoid receptor and diminishes cell sensitivity

28 This effect depends on signaling through the glucocorticoid receptor and is mediated through up-regul

29 Interestingly, the glucocorticoid receptor and its cofactors affect each ot

30 rgent DNA specificities, we examined how the glucocorticoid receptor and its paralogs evolved to bind

31 CHRONO forms a complex with the glucocorticoid receptor and mediates glucocorticoid resp

32 The vast majority of activated glucocorticoid receptor and nuclear factor kappa-b appea

33 nal-dependent transcription factors, such as glucocorticoid receptor and nuclear factor kappa-b, on t

34 tectable plasma HIV-1 RNA), co-regulates the glucocorticoid receptor and PPARgamma and transduces hep

35 ivinA-induced upregulation of liver specific glucocorticoid receptor and Smad2/3 reporter constructs

36 red for alveolar fate specification; rather, glucocorticoid receptor and STAT3 work in parallel to pr

37 e mRNA expression of the beta variant of the glucocorticoid receptor and the 11-beta hydroxysteroid d

38 The glucocorticoid receptor and the mineralocorticoid recept

39 Antagonists of glucocorticoid receptors and kappa opioid receptors (kap

40 Our findings reveal roles for glucocorticoid receptors and kappaORs as mediators of th

41 ter stress through a transient activation of glucocorticoid receptors and more lasting contribution o

42 In mice lacking inflammation, a glucocorticoid receptor antagonist increased ER stress,

43 Here, we analyzed the effects of the glucocorticoid receptor antagonist mifepristone (RU486)

44 icity after juvenile HFD are alleviated by a glucocorticoid receptor antagonist.

45 -3-one 3d (QCA-1093) as a novel nonsteroidal glucocorticoid receptor antagonist.

46 In all species, Sox9, Pax6, and the glucocorticoid receptor are expressed by Muller glia and

47 ous glucocorticoidogenesis and expression of glucocorticoid receptors are inhibited in psoriatic skin

48 the existence of crosstalk between LXA4 and glucocorticoid receptor at the cytosolic level mediated

49 o the molecular interaction between LXA4 and glucocorticoid receptor-based mechanisms.

50 macrophage migration inhibitory factor, and glucocorticoid receptor beta expression and a decrease i

51 s, high-inflammatory gene expression, raised glucocorticoid receptor beta/glucocorticoid receptor alp

52 intron functions as a genomic enhancer where glucocorticoid receptor binding regulates Kappa expressi

53 tually and synergistically enhancing p65 and glucocorticoid receptor binding to the IRAK-M promoter.

54 urine podocytes and enhanced the affinity of glucocorticoid receptor binding to the promoter region o

55 iption factor binding sites corresponding to glucocorticoid receptor binding.

56 Mechanistically, activated glucocorticoid receptor binds directly to a glucocortico

57 lucocorticoid deficiency nor pharmacological glucocorticoid receptor blockade lowered elevated blood

58 by actions on both the mineralocorticoid and glucocorticoid receptors, both of which are expressed in

59 A disordered region at the N-terminus of the glucocorticoid receptor can fine tune how cells respond

60 e importance of this nongenomic role for the glucocorticoid receptor compared with its direct transcr

61 Moreover, glucocorticoid receptor cooperativity with factors, incl

62 tions of corticosterone, increased amygdalar glucocorticoid receptors, decreased time spent in the op

63 Our data demonstrate that activated glucocorticoid receptor, decreasing aromatase expression

64 mpered after cerebral lesions by proteasomal glucocorticoid receptor degradation in brain endothelial

65 precisely timed and depends on a nongenomic glucocorticoid receptor-dependent pathway.

66 ression of CASP1 resulted in cleavage of the glucocorticoid receptor, diminished the glucocorticoid-i

67 Glucocorticoid receptor expression was attenuated in fib

68 ty, likely through modulation of hippocampal glucocorticoid receptor expression, an effect that is li

69 The FKBP5 gene product modulates glucocorticoid receptor function and has been previously

70 We also showed a loss of glucocorticoid receptor (GCR) in pro-inflammatory lympho

71 We also showed a loss of glucocorticoid receptor (GCR) in proinflammatory lymphoc

72 approximately 250 nM and was blocked by the glucocorticoid receptor (GCR) inhibitor RU486 and a mono

73 Glucocorticoid receptor (GCR) signaling is commonly asso

74 phosphorylation and function of the nuclear glucocorticoid receptor (GCR).

75 xpression and epigenetic modification of the glucocorticoid receptor gene (NR3C1) are related to the

76 re we examine signatures of selection on the glucocorticoid receptor gene (Nr3c1) in African starling

77 icate that an epigenetic modification of the glucocorticoid receptor gene promoter is linked to inter

78 bition, demonstrating that Klf13 is a direct glucocorticoid receptor gene target.

79 of a neuron-specific exon 17 promoter of the glucocorticoid receptor (GR) (Nr3c1).

80 rovide insight into the molecular effects of glucocorticoid receptor (GR) activation at a clinically

81 investigations have examined the effects of glucocorticoid receptor (GR) activation prior to inflamm

82 istent with central HPA/I axis induction and glucocorticoid receptor (GR) activation, GR agonists enh

83 ve genomic and non-genomic processes through glucocorticoid receptor (GR) activation.

84 e identified the presence and bioactivity of glucocorticoid receptor (GR) active substances in water;

85 d in vitro estrogen (ER), androgen (AR), and glucocorticoid receptor (GR) activity, along with a broa

86 eatment of human cells with dexamethasone, a glucocorticoid receptor (GR) agonist.

87 lationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are described.

88 Glucocorticoids signal through the glucocorticoid receptor (GR) and are administered clinic

89 which activates transcription factors (TFs) glucocorticoid receptor (GR) and CREB within minutes and

90 ls through its molecular targeting of AR and glucocorticoid receptor (GR) and downstream pro-oxidant

91 oreover, levels of association of H3K9me3 at Glucocorticoid Receptor (GR) and Fibroblast growth Facto

92 We previously showed that the glucocorticoid receptor (GR) and KLF15 form coherent FFL

93 Cross-talk between the glucocorticoid receptor (GR) and other receptors is emer

94 flammation and reduced both the level of the glucocorticoid receptor (GR) and the efficacy of dexamet

95 contributes to the functional status of the glucocorticoid receptor (GR) and to the quality of corti

96 idate the structural activity correlation of glucocorticoid receptor (GR) antagonism, the crystal str

97 The nonselective glucocorticoid receptor (GR) antagonist mifepristone has

98 Here, we demonstrated that the glucocorticoid receptor (GR) antagonist mifepristone red

99 e prevented when animals were treated with a glucocorticoid receptor (GR) antagonist RU486 during soc

100 Glucocorticoid receptor (GR) binding and histone H4 acet

101 immunoprecipitation (ChIP) analysis detected glucocorticoid receptor (GR) binding at the KLF13 promot

102 The glucocorticoid receptor (GR) binds as a homodimer to gen

103 The glucocorticoid receptor (GR) binds the human genome at >

104 roach reveal that Dex- but not CpdA-liganded glucocorticoid receptor (GR) binds to a single glucocort

105 The glucocorticoid receptor (GR) can tether to inflammatory

106 w that binding to nGREs is a property of the glucocorticoid receptor (GR) DNA-binding domain (DBD) no

107 Here, we identify induction of glucocorticoid receptor (GR) expression as a common feat

108 ng reduced progesterone receptor (PR) and/or glucocorticoid receptor (GR) expression or activity.

109 ave increased anxiety, decreased hippocampal glucocorticoid receptor (GR) expression, and increased h

110 Impaired glucocorticoid receptor (GR) function has been associate

111 stration, indicating an additional effect on glucocorticoid receptor (GR) function.

112 ation status, only allelic variation for the glucocorticoid receptor (GR) gene accounted for a signif

113 t clinical need by genetic disruption of the glucocorticoid receptor (GR) gene using electroporation

114 Although redox regulation of the glucocorticoid receptor (GR) has been reported, it has n

115 lammatory transcription factors by monomeric glucocorticoid receptor (GR) has long been viewed as cen

116 n ZFP36L2 is a transcriptional target of the glucocorticoid receptor (GR) in BFU-Es and is required f

117 ort that mice with selective deletion of the glucocorticoid receptor (GR) in DCs (GR(CD11c-cre)) were

118 ome-wide regulatory actions of ZNF764 on the glucocorticoid receptor (GR) in HeLa cells as a model sy

119 te corticosteroid efficacy, interacting with glucocorticoid receptor (GR) in patients with chronic rh

120 dies revealed that Foxa3 is regulated by the glucocorticoid receptor (GR) in preadipocytes, adipocyte

121 g frequencies via promiscuous binding to the glucocorticoid receptor (GR) in T cells.

122 antitatively explore the organization of the glucocorticoid receptor (GR) in the interphase nucleus o

123 ytoskeletal organization, interacts with the glucocorticoid receptor (GR) in the nucleus of human pod

124 The glucocorticoid receptor (GR) is a ligand-regulated trans

125 The glucocorticoid receptor (GR) is a ligand-regulated trans

126 The glucocorticoid receptor (GR) is a member of the nuclear

127 The glucocorticoid receptor (GR) is a steroid-hormone-activa

128 lation of stress and immune functions by the glucocorticoid receptor (GR) is also an integral part of

129 The glucocorticoid receptor (GR) is essential for the stress

130 Given that glucocorticoid receptor (GR) is highly expressed in trip

131 The glucocorticoid receptor (GR) is the major receptor for t

132 Emerging data suggest that the glucocorticoid receptor (GR) is upregulated in this cont

133 ion, and, using NMR, the conformation of two glucocorticoid receptor (GR) isoforms that differ by a s

134 The podocyte-specific glucocorticoid receptor (GR) knockout mice had similar r

135 ese effects were abrogated when reducing the glucocorticoid receptor (GR) levels with siRNA.

136 There is a therapeutic need for glucocorticoid receptor (GR) ligands that distinguish be

137 eases has been augmented with a new group of glucocorticoid receptor (GR) ligands.

138 Therefore, the development of novel glucocorticoid receptor (GR) modulators with an increase

139 In asthma, LABAs enhance glucocorticoid receptor (GR) nuclear translocation in th

140 Because glucocorticoid receptor (GR) nuclear translocation is ke

141 ugh dexamethasone-mediated activation of the glucocorticoid receptor (GR) potently repressed expressi

142 The steroid hormone-activated glucocorticoid receptor (GR) regulates cellular stress p

143 thyltransferase 1 (WBSCR22/Merm1) as a novel glucocorticoid receptor (GR) regulator relevant to human

144 ted by dexamethasone because it contains two glucocorticoid receptor (GR) response elements (GREs).

145 ition, pridopidine treatment upregulated the glucocorticoid receptor (GR) response, D1R-associated ge

146 Enhanced glucocorticoid receptor (GR) sensitivity is present in p

147 By utilizing glucocorticoid receptor (GR) signaling as a model system

148 Glucocorticoid receptor (GR) signaling has recently been

149 Glucocorticoid receptor (GR) signaling was the only conv

150 regarding the actions of antidepressants on glucocorticoid receptor (GR) signalling.

151 In this study, we inactivated the glucocorticoid receptor (GR) specifically in kidney epit

152 le in vitro studies have demonstrated that a glucocorticoid receptor (GR) splice isoform, beta-isofor

153 ds because parbendazole does not up-regulate glucocorticoid receptor (GR) target genes and is not inh

154 with other steroid hormone receptors such as glucocorticoid receptor (GR) that plays a critical role

155 nal mechanisms and impair the ability of the glucocorticoid receptor (GR) to activate it, suggesting

156 s GW7647 and fenofibrate synergizes with the glucocorticoid receptor (GR) to promote BFU-E self-renew

157 steroids that are activating ligands for the glucocorticoid receptor (GR) transcription factor.

158 Glucocorticoid receptor (GR) transcriptional activity an

159 MPA, similar to dexamethasone, increases glucocorticoid receptor (GR) transcriptional activity, i

160 her there was a defect in the actions of the glucocorticoid receptor (GR) underlying the ability of C

161 mined the DNA-binding pattern of the nuclear glucocorticoid receptor (GR) using chromatin immunopreci

162 ion of cortisol specificity in the ancestral glucocorticoid receptor (GR) was contingent on permissiv

163 The genomic loci bound by the glucocorticoid receptor (GR), a hormone-activated transc

164 These drugs bind to the glucocorticoid receptor (GR), a ligand-activated transcr

165 tions of glucocorticoids are mediated by the glucocorticoid receptor (GR), a member of the nuclear re

166 The glucocorticoid receptor (GR), a nuclear receptor and maj

167 In contrast, the GFP-fused glucocorticoid receptor (GR), acting through the same HR

168 The estrogen receptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1

169 amma gene regulation by glucocorticoids, the glucocorticoid receptor (GR), and its coregulators is po

170 us levels of the androgen receptor (AR), the glucocorticoid receptor (GR), and the microRNA hsa-miR-2

171 These effects were dependent on the glucocorticoid receptor (GR), blocked by the GR antagoni

172 gulates downstream hormone signaling via the glucocorticoid receptor (GR), but the role of this molec

173 our key TFs regulating the fasting response: glucocorticoid receptor (GR), cAMP responsive element bi

174 like transcription factor 15 (KLF15) and the glucocorticoid receptor (GR), cooperate to stimulate pro

175 Dexamethasone (DEX), a synthetic ligand for glucocorticoid receptor (GR), is routinely used to stimu

176 ive specific binding of two TFs, p53 and the glucocorticoid receptor (GR), is transient.

177 The glucocorticoid receptor (GR), like many signaling protei

178 rogen receptor (AR), estrogen receptor (ER), glucocorticoid receptor (GR), mineralocorticoid receptor

179 alpha (Esr1), estrogen receptor beta (Esr2), glucocorticoid receptor (Gr), mineralocorticoid receptor

180 Upon activation of the glucocorticoid receptor (GR), proximal regions of activa

181 stimulates BC cell growth by binding to the glucocorticoid receptor (GR), the nuclear receptor of en

182 of an alternative nuclear hormone receptor, glucocorticoid receptor (GR), which has similar DNA-bind

183 associated with nuclear translocation of the glucocorticoid receptor (GR), which is essential for glu

184 tivation and repression, are mediated by the glucocorticoid receptor (GR), which is known to bind as

185 Glucocorticoids (GCs)-ligands of the glucocorticoid receptor (GR)-are widely used to treat in

186 Using a glucocorticoid receptor (GR)-based fusion protein system

187 ypoxia response element (HRE) reporters in a glucocorticoid receptor (GR)-dependent manner.

188 ly reported that a nuclear receptor cofactor-glucocorticoid receptor (GR)-interacting protein (GRIP)1

189 It could enhance glucocorticoid receptor (GR)-luciferase activity and fac

190 Glucocorticoid receptor (GR)-mediated activity was deter

191 ELF complex subunits, which are to attenuate glucocorticoid receptor (GR)-mediated gene induction, re

192 Thus, although glucocorticoid receptor (GR)-mediated transactivation is

193 ation and DNA-binding dictate the outcome of glucocorticoid receptor (GR)-mediated transcriptional re

194 The mechanism involves a fetal glucocorticoid receptor (GR)-PPARalpha axis in which GR

195 in, and many of the factors contributing to, glucocorticoid receptor (GR)-regulated gene induction ar

196 Finally, we show that glucocorticoid receptor (GR)-regulated genes are signifi

197 omain-containing protein Elk1 (Elk1) and the glucocorticoid receptor (GR).

198 anscription factor binding, including to the glucocorticoid receptor (GR).

199 the mouse uterus contains high levels of the glucocorticoid receptor (GR).

200 it tumor growth and induce apoptosis via the glucocorticoid receptor (GR).

201 ss of androgen receptor (AR) blockade by the glucocorticoid receptor (GR).

202 HF is a weak endogenous agonist of the human glucocorticoid receptor (GR).

203 hosphate (FPP) and cortisol, ligands for the glucocorticoid receptor (GR).

204 optosis in lymphoid malignancies through the glucocorticoid receptor (GR).

205 tions of glucocorticoids are mediated by the glucocorticoid receptor (GR).

206 demonstrate that the transient appearance of glucocorticoid receptor (GR)/BRG1-dependent, TOP2beta-me

207 lated Transcription Coactivator 2 (Crtc2) or Glucocorticoid Receptor (GR, NR3C1) were classified base

208 A methylation of the exon 1F promoter of the glucocorticoid receptor (GR-1F) gene (NR3C1) in peripher

209 lated and post-translationally inhibited the glucocorticoid receptor (GR-alpha) and histone deacetyla

210 actor (BDNF) increase the desensitization of glucocorticoid receptors (GR) and vulnerability to stres

211 Phosphorylation of glucocorticoid receptors (GR) by brain-derived neurotrop

212 The location of glucocorticoid receptors (GR) implicated in depression s

213 To determine the role of forebrain glucocorticoid receptors (GR) in behavioral responses to

214 ene repression by transcription factors, and glucocorticoid receptors (GR) in particular, is a critic

215 wn strategy (short hairpin RNA targeting the glucocorticoid receptor [GR]) to attenuate PFC GR signal

216 ical symptoms and variation in genes, NR3C1 (glucocorticoid receptor; GR) and NR3C2 (mineralocorticoi

217 -term anxiety and pain through activation of glucocorticoid receptors (GRs) and corticotropin-releasi

218 hanisms underlying the opposing functions of glucocorticoid receptors (GRs) and estrogen receptor alp

219 Glucocorticoid receptors (GRs) are regulators of inflamm

220 s, we assessed the hippocampal expression of glucocorticoid receptors (GRs) at postnatal day 12 (P12)

221 ind to mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) in the hippocampus to reg

222 ough interaction with ubiquitously expressed glucocorticoid receptors (GRs), this steroid hormone has

223 nalysis for the master regulator STAT5A, the glucocorticoid receptor, H3K27ac and MED1 identified 440

224 t in PFC of repeatedly stressed rats, active glucocorticoid receptor had the increased binding to the

225 miR-433 can target the glucocorticoid receptor; however, glucocorticoid recepto

226 inter-regional variations relate to those in glucocorticoid receptor (HPA) and androgen receptor (HPG

227 and fear-circuit dysfunction, inflammation, glucocorticoid receptor hypersensitivity) in addition to

228 viors, as well as hyperactive fear circuits, glucocorticoid receptor hypersensitivity, and response t

229 Furthermore, chronic stress decreases glucocorticoid receptor immunoreactivity specifically in

230 bition is initiated by a membrane-associated glucocorticoid receptor in BLA principal neurons.

231 le for regulatory networks downstream of the glucocorticoid receptor in excessive alcohol drinking du

232 generated mice with targeted deletion of the glucocorticoid receptor in muscle (mGRKO mice).

233 or p25, up-regulation and phosphorylation of glucocorticoid receptors, increased HDAC2 expression, an

234 tic inhibition in BLA neurons via a membrane glucocorticoid receptor-induced release of 2-AG at GABA

235 Further, membrane glucocorticoid receptor influences glucocorticoid recept

236 Further, glucocorticoid receptor inhibition demonstrated partial

237 It was also abolished by the glucocorticoid receptor inhibitor, mifepristone, and a m

238 nd the steroid receptor coactivator 1 or the glucocorticoid receptor-interacting protein 1.

239 ry we present an in silico simulation of the glucocorticoid receptor interaction network, linked to d

240 We focused on ERalpha/glucocorticoid receptor interplay and demonstrated that

241 We conclude that the podocyte glucocorticoid receptor is important for limiting protei

242 ent evidence also demonstrates that membrane glucocorticoid receptor is present in numerous cell type

243 gene, ST13, coding for a cochaperone of the glucocorticoid receptor, is associated with exacerbation

244 Tamoxifen-inducible chondrocyte-targeted glucocorticoid receptor-knockout (chGRKO) mice were gene

245 inhibition of CASP1 significantly increased glucocorticoid receptor levels and mitigated glucocortic

246 and also by compound A, a novel nonsteroidal glucocorticoid receptor ligand.

247 lt skeletal muscle fibres, are mediated by a glucocorticoid receptor localised in the extracellular m

248 s regulating the HPA axis - particularly the glucocorticoid receptor - may facilitate adaptation to c

249 ling, we investigated the role of membranous glucocorticoid receptor (mbGR) by using cell-impermeable

250 er chronic stress may be caused by loss of a glucocorticoid receptor-mediated brake on interneuron ac

251 ntative cell line, as measured by changes in glucocorticoid receptor-mediated gene mRNA levels.

252 ss both TLR-mediated expression of IL-10 and glucocorticoid receptor-mediated transcription of glucoc

253 of the Cnr1 promoter and down-regulation of glucocorticoid-receptor-mediated expression of CNR1 in L

254 n both in vitro and in vivo, suggesting that glucocorticoid receptor might be a potential target for

255 (androgen receptor, estrogen receptor alpha, glucocorticoid receptor, mineralocorticoid receptor, and

256 entification of 5 (BMS-341) as a dissociated glucocorticoid receptor modulator.

257 nonsteroidal, selective indazole ether-based glucocorticoid receptor modulators (SGRMs) was developed

258 of functional variants and haplotypes in the glucocorticoid receptor (NR3C1) and mineralocorticoid re

259 ignaling target HES1 expression was high and glucocorticoid receptor (NR3C1) low at the crypt base an

260 Glucocorticoids act on the glucocorticoid receptor (NR3C1) to repress inflammatory

261 nd histone acetylation at genes encoding the glucocorticoid receptor (NR3C1), CNR1, and TRPV1.

262 Glucocorticoid receptor occupancy at the Cxcl5 locus sho

263 ger RNA in female rats was due to actions of glucocorticoid receptors on the orexin promoter, as dete

264 es have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many

265 in the expression of the beta variant of the glucocorticoid receptor or the 11-beta hydroxysteroid de

266 c (iAs) were prevented when signaling of the glucocorticoid receptor pathway was inhibited.

267 periments demonstrated that neither GILZ nor glucocorticoid receptor play a role in TLR-induced IL-10

268 target the glucocorticoid receptor; however, glucocorticoid receptor protein abundance was unaffected

269 e as a major negative regulator of the NR3C1 glucocorticoid receptor protein activity driving glucoco

270 h, aiming to generate a Boolean model of the glucocorticoid receptor protein interaction network that

271 ds can repress inflammatory gene expression, glucocorticoid receptor recruitment increases expression

272 ow that TBL1XR1 knockdown results in reduced glucocorticoid receptor recruitment to glucocorticoid re

273 ity of p160 coactivators (SRC-1 and TIF2) in glucocorticoid receptor-regulated gene induction and rep

274 ants in NR3C1 that alter the activity of the glucocorticoid receptor (rs56149945, rs41423247, and rs6

275 (Ser203, 211, and 226) located in the human glucocorticoid receptor's (GR's) ID AF1 domain.

276 ult offspring of Holocaust survivors in both glucocorticoid receptor sensitivity and vulnerability to

277 od mononuclear cells and its relationship to glucocorticoid receptor sensitivity in Holocaust offspri

278 Because glucocorticoid receptor signaling is known to regulate e

279 Induction of glucocorticoid receptor signaling or forkhead box (FOXO)

280 was observed for genes corresponding to the glucocorticoid receptor signaling pathway.

281 tion changes, with activation of NK cell and glucocorticoid receptor signaling transcripts.

282 in osteoblasts by regulating sensitivity to glucocorticoid receptor signaling.

283 e signature reflecting adaptive immunity and glucocorticoid receptor signaling.

284 ng genes correspond to adaptive immunity and glucocorticoid receptor signaling.

285 ated cortisol stress, both of which activate glucocorticoid receptor signaling.

286 through mitogen-activated protein kinase and glucocorticoid receptor signalling, respectively.

287 sulating more interactions/genes involved in glucocorticoid receptor signalling.

288 dentified Pik3r1 (also called p85alpha) as a glucocorticoid receptor target gene.

289 Although GCs have high affinity for the glucocorticoid receptor, they also bind and activate the

290 ry effect relies on the ability of activated glucocorticoid receptor to regulate the aromatase gene t

291 In light of its role in glucocorticoid receptor transactivation, we investigated

292 aining a sequence mutation that introduces a glucocorticoid receptor transcription factor binding sit

293 d nuclear receptor translocation, activating glucocorticoid receptor transcriptional targets.

294 membrane glucocorticoid receptor influences glucocorticoid receptor translocation to the nucleus eff

295 We demonstrate that human glucocorticoid receptor tunes this signaling in vivo by

296 entified the products of NR3C1 (encoding the glucocorticoid receptor), TXNIP (encoding a glucose-feed

297 Among these, the gene coding for the glucocorticoid receptor was independently identified as

298 The expression of CCR7 and of the glucocorticoid receptor was measured by using flow cytom

299 l rescue effect depends on activation of the glucocorticoid receptor with increased phosphorylation o

300 ckade as well as genetic manipulation of the glucocorticoid receptor within DCs inhibited Ms4a8a and