ライフサイエンスコーパス: glucose-1-phosphate

1 eatine+Glycogen+H(+)Creatine+Glycogen(n)(-1)+Glucose-1-Phosphate ).

2 a glucose acceptor, releasing phosphate from glucose 1-phosphate.

3 ucose 6-phosphate, fructose 6-phosphate, and glucose 1-phosphate.

4 phosphorolysis of GDP-D-glucose to GDP and D-glucose 1-phosphate.

5 Glc PPases having high apparent affinity for glucose 1-phosphate.

6 r AMP, and a 2-fold decrease in the S0.5 for glucose 1-phosphate.

7 r AMP, and a 3-fold decrease in the S0.5 for glucose 1-phosphate.

8 y of AMP or the cooperativity and binding of glucose 1-phosphate.

9 sis of their specificity for alpha- and beta-glucose-1-phosphate.

10 in Vmax, a 10-fold decrease in the S0.5 for glucose 1-phosphate, a 10-fold increase in the Ka for AM

11 1-phosphate adenylyltransferase; ADP:alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27) ca

12 -phosphate adenylyltransferase; ADP: alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27), a

13 ility of ADP-glucose pyrophosphorylase (AGP; glucose-1-phosphate adenylyltransferase; ADP: alpha-D-gl

14 ADPglucose pyrophosphorylase (glucose-1-phosphate adenylyltransferase; ADP:alpha-D-glu

15 (ADP-Glc PPase) catalyzes the conversion of glucose 1-phosphate and adenosine 5'-triphosphate to ADP

16 Studies of inhibition by glucose 1-phosphate and AMP indicated that Cys(379) was

17 e (ADPGlc PPase) catalyzes the conversion of glucose 1-phosphate and ATP to ADP-glucose and pyrophosp

18 ucomutases catalyze the interconversion of D-glucose 1-phosphate and D-glucose 6-phosphate, a reactio

19 ent with1.4 nm and is permeable for glucose, glucose 1-phosphate and glucose 6-phosphate, but not for

20 The interconversion of glucose 1-phosphate and glucose 6-phosphate, catalyzed b

21 hosphate and mannose 6-phosphate, as well as glucose 1-phosphate and glucose 6-phosphate, in vitro.

22 nd gluconeogenesis through the conversion of glucose 1-phosphate and glucose 6-phosphate.

23 cytidylyltransferase, which utilizes alpha-D-glucose 1-phosphate and MgCTP as substrates.

24 the mutations to enhance binding of AMP and glucose 1-phosphate and to raise catalytic activity sugg

25 e is a competitive inhibitor with respect to glucose 1-phosphate and uncompetitive with respect to ph

26 yze the degradation of glycogen into alpha-D-glucose-1-phosphate and are targets for the development

27 stantially less affinity for the substrates, glucose-1-phosphate and ATP and an increased Ka for the

28 Michaelis constant values for the substrates glucose-1-phosphate and ATP but requires 6- to 10-fold g

29 Using this method, the conversion between glucose-1-phosphate and glucose-6-phosphate can be direc

30 The values of K(m) for glucose-1-phosphate and glucose-6-phosphate were determi

31 otype and accumulated galactose 1-phosphate, glucose 1-phosphate, and GDP-glucose when grown on galac

32 After stopping the reaction that uses [14C]glucose 1-phosphate as a substrate, the ADP-[14C]glucose

33 PGM) catalyzes the interconversion of beta-d-glucose 1-phosphate (beta-G1P) and beta-d-glucose 6-phos

34 (betaPGM) catalyzes the conversion of beta-d-glucose 1-phosphate (betaG1P) derived from maltose to be

35 (betaPGM) catalyzes isomerization of beta-D-glucose 1-phosphate (betaG1P) into D-glucose 6-phosphate

36 ily (HADSF) catalyzes the conversion of beta-glucose 1-phosphate (betaG1P) to glucose 6-phosphate (G6

37 cose 2-fold, but has little effect on AMP or glucose 1-phosphate binding or cooperativity.

38 s AMP cooperativity but has little effect on glucose 1-phosphate binding or cooperativity.

39 of the enzyme including the N-terminus, the glucose-1-phosphate-binding site, and the ATP-binding si

40 Finally, P46 overexpression enhanced glucose 1-phosphate but not fructose 6-phosphate hydroly

41 e synthesized from cellobiose (CB) and alpha-glucose 1-phosphate by reverse phosphorolysis, using enz

42 th ADP-glucose and dithiothreitol or by ATP, glucose- 1-phosphate, Ca2+, and dithiothreitol.

43 e three-dimensional structure of the alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella

44 rometry and one- and two-dimensional NMR CTP:glucose-1-phosphate cytidylyltransferase, CDP-Glc 4,6-de

45 on of this ligand is catalyzed by the enzyme glucose-1-phosphate cytidylyltransferase, which utilizes

46 actose 1-phosphate to form UDP-galactose and glucose 1-phosphate during normal cellular metabolism.

47 zes the conversion of glucose-6-phosphate to glucose-1-phosphate during growth on glucose, and theref

48 er, that the rate of enzymatic hydrolysis of glucose-1-phosphate (G1P) adsorbed on goethite by acid p

49 ur experiments, ADPG was obtained by heating glucose-1-phosphate (G1P) and ATP in the presence of cya

50 ncentration starch solution, suggesting more glucose 1-phosphate generated.

51 m, where it catalyzes the interconversion of glucose 1-phosphate (Glc-1-P) and glucose 6-phosphate (G

52 hosphate (Gal-1-P) to form UDP-galactose and glucose 1-phosphate (Glc-1-P) through a double displacem

53 1-phosphate (Gal-1-P) into UDP-galactose and glucose-1-phosphate (Glc-1-P) by a double displacement m

54 be involved in the binding of the substrate glucose-1-phosphate (Glc-1-P).

55 ed a relatively high degree of acceptance of glucose-1-phosphate (Glc1P), mannose-1-phosphate (Man1P)

56 ction binds UDP-glucose (UDP-Glu), displaces glucose-1-phosphate (glu-1-P), and forms the UMP-GALT in

57 ytes--catechol, dopamine, fructose, glucose, glucose-1-phosphate, glucose-6-phosphate, galactose, lac

58 ey enzyme that breaks down glycogen to yield glucose-1-phosphate in order to restore depleted energy

59 ins a covalent uridylylated intermediate and glucose-1-phosphate in the active site, as well as a str

60 ariety of cellular constituents derived from glucose-1-phosphate, including trehalose.

61 e formation of glucose 1,6-bisphosphate from glucose 1-phosphate is in rapid equilibrium relative to

62 ay by which beta-D-galactose is converted to glucose 1-phosphate is known as the Leloir pathway and c

63 ate <--> UDP-galactose <--> UDP-glucose <--> glucose 1-phosphate <--> glucose 6-phosphate <--> fructo

64 studies indicate that it partitions to form glucose 1-phosphate or glucose 6-phosphate 14.3 times mo

65 complex that is not competent to form either glucose 1-phosphate or glucose 6-phosphate directly.

66 Mg(II) cofactor and either of the substrates glucose 1-phosphate or glucose 6-phosphate produced crys

67 The [14C]glucose 1-phosphate that did not react is easily elimina

68 idues stemmed from fructose 6-phosphate, not glucose 1-phosphate; therefore GDP-mannose (guanosine 5'

69 ridine 5'-diphosphate galactose (UDPGal) and glucose-1-phosphate through a double displacement mechan

70 evaluated as potential inhibitors of alpha-D-glucose 1-phosphate thymidylyltransferase (Cps2L), the f

71 the dTDP-L-rhamnose biosynthetic pathway is glucose-1-phosphate thymidylyltransferase (RmlA).

72 ars striking similarity to that observed for glucose-1-phosphate thymidylyltransferase and 4-diphosph

73 The assay was validated using the model glucose-1-phosphate thymidylyltransferase from Salmonell

74 yme that is similar to that reported for the glucose-1-phosphate thymidylyltransferases.

75 ys that begin with the attachment of alpha-D-glucose 1-phosphate to either CTP or dTTP.

76 This mutant is unable to convert glucose-1-phosphate to ADP-glucose, the precursor of sta

77 verts galactose-1-phosphate + UDP-glucose to glucose-1-phosphate + UDP-galactose.

78 lpha-phosphoglucomutase (PgcA) and UTP:alpha-glucose 1-phosphate uridyltransferase (GtaB) homologs ar

79 In addition, genes predicated to encode a glucose-1-phosphate uridylyltransferase (galU), a UDP-N-

80 Enolase, UTP-glucose-1-phosphate uridylyltransferase and polygalactur

81 mily of glycosyl hydrolases, and UGP1, a UTP-glucose-1-phosphate uridylyltransferase which synthesize

82 Prokaryotic and eukaryotic glucose-1-phosphate uridylyltransferases (EC 2.7.7.9) ca

83 ATP and glucose 1-phosphate were successfully modeled in the pro

84 oglucomutase (PGM) causes an accumulation of glucose 1-phosphate when yeast cells are grown with gala

85 enzyme which metabolizes glycogen, producing glucose-1-phosphate, which can be used for the productio

86 ylases catalyze the breakdown of glycogen to glucose-1-phosphate, which enters glycolysis to fulfill

87 arch, and together they generate glucose and glucose-1-phosphate, which then feed into the novel glyc

88 sensitivity at lower concentrations of [14C]glucose 1-phosphate without compromising the blanks obta