ライフサイエンスコーパス: glucose-6-phosphate dehydrogenase

1 reased activity, but not protein content, of glucose 6-phosphate dehydrogenase.

2 ine does not affect the overall structure of glucose 6-phosphate dehydrogenase.

3 sses hexokinase and the rate-limiting enzyme glucose-6-phosphate dehydrogenase.

4 regeneration system and the cytosolic enzyme glucose-6-phosphate dehydrogenase.

5 a role outside of its function in activating glucose-6-phosphate dehydrogenase.

6 ctions based on the molecular model of human glucose-6-phosphate dehydrogenase.

7 red lactate dehydrogenase and heat-denatured glucose-6-phosphate dehydrogenase.

8 aemia, and a mutation of G6PD, which encodes glucose-6-phosphate dehydrogenase.

9 r non-specific glycolytic proteins such as d-glucose-6-phosphate dehydrogenase.

10 ence of 6-aminonicotinamide, an inhibitor of glucose-6-phosphate dehydrogenase.

11 ntapeptide derived from the metabolic enzyme glucose-6-phosphate dehydrogenase.

12 no significant homology with NADP-dependent glucose-6-phosphate dehydrogenases.

13 extensive similarity to an unusual group of glucose-6-phosphate dehydrogenases.

14 ing for cellular NADPH regenerating enzymes (glucose 6-phosphate dehydrogenase, 6-phosphogluconate de

15 ctivity of pentose phosphate pathway enzymes glucose 6-phosphate dehydrogenase, 6-phosphogluconate de

16 ative pentose phosphate pathway (hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate de

17 The enzyme activities of glucose-6-phosphate dehydrogenase, 6-phosphogluconate de

18 oncomitant inhibition of the parasite enzyme glucose-6-phosphate dehydrogenase-6-phosphogluconolacton

19 In P. falciparum , the bifunctional enzyme glucose-6-phosphate dehydrogenase-6-phosphogluconolacton

20 e (70%), phosphoglucose isomerase (65%), and glucose-6-phosphate dehydrogenase (85%), but not phospho

21 ively, decreased TAL expression up-regulated glucose-6-phosphate dehydrogenase activities and GSH lev

22 TAL overexpression down-regulated glucose-6-phosphate dehydrogenase activities and GSH lev

23 8 hrs post-PMA injury with a 40% increase in glucose-6-phosphate dehydrogenase activity and a 32% inc

24 nal requirement mediating selection for high glucose-6-phosphate dehydrogenase activity.

25 First, samples were spiked with glucose-6-phosphate dehydrogenase, an enzyme of known mo

26 rexpression of TAL resulted in a decrease in glucose 6-phosphate dehydrogenase and 6-phosphogluconate

27 reduced levels of TAL resulted in increased glucose 6-phosphate dehydrogenase and 6-phosphogluconate

28 maximal at 72 hrs with an increase of 98% in glucose-6-phosphate dehydrogenase and 346% in 6-phosphog

29 Two NAD-dependent dehydrogenases (glucose-6-phosphate dehydrogenase and 6-phosphogluconate

30 cal NADPH homeostasis, which is regulated by glucose-6-phosphate dehydrogenase and AMP kinase.

31 enzymes of human red blood cell metabolism: glucose-6-phosphate dehydrogenase and pyruvate kinase.

32 ations involving conversion to N(tz) ADPH by glucose-6-phosphate dehydrogenase and reoxidation to N(t

33 Evaluations for glucose-6-phosphate dehydrogenase and thiopurine S-methy

34 cids; it overlaps the 5' end of zwf (encodes glucose-6-phosphate dehydrogenase) and is followed immed

35 ed elevations in the mRNAs for malic enzyme, glucose-6-phosphate dehydrogenase, and 6-phosphogluconat

36 blood cell polymorphisms (ie, hemoglobin S, glucose-6-phosphate dehydrogenase, and alpha-thalassemia

37 n of branched-chain keto acid dehydrogenase, glucose-6-phosphate dehydrogenase, and amidase in both s

38 three enzymes (catechol-O-methyltransferase, glucose-6-phosphate dehydrogenase, and glyceraldehyde-3-

39 ), oxidative stress (glutathione peroxidase, glucose-6-phosphate-dehydrogenase, and ascorbate peroxid

40 , a plasma membrane (PM) marker; activity of glucose-6-phosphate dehydrogenase, assayed as cytosolic

41 h the construction of the molecular model of glucose-6-phosphate dehydrogenase, based on the structur

42 A1 substantially reduced the inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal

43 as exemplified for the reaction catalyzed by glucose-6-phosphate dehydrogenase by comparing the 1-(13

44 eric molecular mass of 33.8kDa while that of glucose-6-phosphate dehydrogenase (D-glucose 6-phosphate

45 acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd).

46 Other abnormal hemoglobins, glucose-6-phosphate dehydrogenase deficiency and pyruvat

47 [95% confidence interval {CI}, 0.52-0.90]), glucose-6-phosphate dehydrogenase deficiency in female c

48 Glucose-6-phosphate dehydrogenase deficiency serves as a

49 lasmic PICD, the phenotypes of patients with glucose-6-phosphate dehydrogenase deficiency suggest tha

50 lpha-thalassemia, 0.3%; ABO group, 0.3%; and glucose-6-phosphate dehydrogenase deficiency, 0.5%) and

51 tors for neurotoxicity, such as prematurity, glucose-6-phosphate dehydrogenase deficiency, or hypoxia

52 t Asian ovalocytosis and two common forms of glucose-6-phosphate dehydrogenase deficiency.

53 No correlation with sickle cell trait or glucose-6-phosphate-dehydrogenase deficiency was observe

54 Glucose-6-phosphate dehydrogenase deficient patients on

55 splantation studies in cats heterozygous for glucose-6-phosphate-dehydrogenase, different estimates o

56 ntration dependent stabilising effect on the glucose-6-phosphate dehydrogenase dimer.

57 actone, produced from glucose 6-phosphate by glucose-6-phosphate dehydrogenase (EC 1.1.1.49).

58 The glucose-6-phosphate dehydrogenase-encoding gene (G6PD) b

59 Conditional expression of the glucose-6-phosphate dehydrogenase-encoding gene zwf, sho

60 d sex-specific QTL underlying differences in glucose-6-phosphate dehydrogenase enzyme activity betwee

61 Patients with glucose-6-phosphate dehydrogenase enzyme activity of les

62 ith uncomplicated falciparum malaria, normal glucose-6-phosphate dehydrogenase enzyme levels, and hem

63 either 6PGD or another oxidative PPP enzyme, glucose-6-phosphate dehydrogenase, exhibit non-immune he

64 a substrate for an enzyme, F(420)-dependent glucose-6-phosphate dehydrogenase (Fgd), found in few ba

65 The gene fgd, which codes for F420-dependent glucose-6-phosphate dehydrogenase (FGD), was cloned from

66 ide transfer coenzyme for an F(420)-specific glucose-6-phosphate dehydrogenase (Fgd).

67 most commonly mediated by loss of a specific glucose-6-phosphate dehydrogenase (FGD1) or its deazafla

68 of Asp-177 in the His-Asp catalytic dyad of glucose 6-phosphate dehydrogenase from Leuconostoc mesen

69 The catalytic mechanism of glucose 6-phosphate dehydrogenase from Leuconostoc mesen

70 A large excess of ALDH3A1 also protected glucose-6-phosphate dehydrogenase from inactivation beca

71 gene, previously identified as essential for glucose-6-phosphate dehydrogenase function.

72 NADPH is produced by glucose-6-phosphate dehydrogenase (G-6-PDase) and 6-phos

73 immunofluorescence microscopy has shown that glucose-6-phosphate dehydrogenase (G-6-PDase), the rate-

74 tatus of mitochondrial glutathione (GSH) and glucose 6-phosphate dehydrogenase (G6-PD) was restored b

75 -yl)-2,5-diphenyltetrazolium bromide] (MTT), glucose-6-phosphate dehydrogenase (G6DP), and calcein AM

76 Salmonella typhimurium zwf mutants lacking glucose 6-phosphate dehydrogenase (G6PD) activity have i

77 Individuals with glucose 6-phosphate dehydrogenase (G6PD) deficiency are

78 m embryonic stem cells in which the X-linked glucose 6-phosphate dehydrogenase (G6PD) gene had been t

79 Human glucose 6-phosphate dehydrogenase (G6PD) has a particula

80 autologous marrow transplantation studies of glucose 6-phosphate dehydrogenase (G6PD) heterozygous fe

81 ession of a thoroughly characterized enzyme: glucose 6-phosphate dehydrogenase (G6PD) in human erythr

82 Glucose 6-phosphate dehydrogenase (G6PD) is a cytosolic

83 Glucose 6-phosphate dehydrogenase (G6PD) is the most com

84 inactivating ATM or its downstream effector glucose 6-phosphate dehydrogenase (G6PD) sensitizes AML

85 gnment of the amino acid (aa) sequence of 52 glucose 6-phosphate dehydrogenase (G6PD) species from 42

86 0 from the 109 kDa Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase (G6PD) were assigned b

87 , HDACi selectively enhance transcription of glucose 6-phosphate dehydrogenase (G6PD).

88 eductant, NADPH by impairing the activity of glucose 6-phosphate dehydrogenase (G6PD).

89 ation and isocitrate dehydrogenase (IDH) and glucose-6-phosphate dehydrogenase (G6PD) activities are

90 riation in isocitrate dehydrogenase (IDH) or glucose-6-phosphate dehydrogenase (G6PD) activity in a s

91 Glucose-6-phosphate dehydrogenase (G6PD) activity is ess

92 Glucose-6-phosphate dehydrogenase (G6PD) activity was in

93 ATM activation induces glucose-6-phosphate dehydrogenase (G6PD) activity, the l

94 ify cell death based upon the measurement of glucose-6-phosphate dehydrogenase (G6PD) activity.

95 Unexpectedly, Glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogl

96 d on the oxidation of G6P in the presence of glucose-6-phosphate dehydrogenase (G6PD) and nicotinamid

97 atty acids inhibit the expression of hepatic glucose-6-phosphate dehydrogenase (G6PD) by changes in t

98 reduction of NADPH generation via a block of glucose-6-phosphate dehydrogenase (G6PD) by treatment wi

99 .-) production, suggesting that intranuclear glucose-6-phosphate dehydrogenase (G6PD) can control NOX

100 s study investigates the significance of the glucose-6-phosphate dehydrogenase (G6PD) catalyzed oxida

101 mutations of the housekeeping gene encoding glucose-6-phosphate dehydrogenase (G6PD) cause G6PD defi

102 out dose-dependent haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficiencies ha

103 ), alpha thalassaemia, ABO blood groups, and glucose-6-phosphate dehydrogenase (G6PD) deficiency enco

104 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a

105 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is b

106 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is t

107 The global prevalence of X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency is t

108 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is t

109 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is t

110 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is t

111 omplicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency.

112 l malaria risk factors, and we also assessed glucose-6-phosphate dehydrogenase (G6PD) enzyme activity

113 The inhibition of glucose-6-phosphate dehydrogenase (G6PD) expression by a

114 Glucose-6-phosphate dehydrogenase (G6PD) functions as th

115 Expression of glucose-6-phosphate dehydrogenase (G6PD) gene during sta

116 2) IL-1beta stimulated increased activity of glucose-6-phosphate dehydrogenase (G6PD) in a time- and

117 s in mitochondria, whereas chloroquine and a glucose-6-phosphate dehydrogenase (G6PD) inhibitor affec

118 Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme

119 The gene coding for glucose-6-phosphate dehydrogenase (G6PD) is subject to p

120 The reaction catalyzed by glucose-6-phosphate dehydrogenase (G6PD) is the first, r

121 Glucose-6-phosphate dehydrogenase (G6PD) is the principa

122 Glucose-6-phosphate dehydrogenase (G6PD) is the rate-lim

123 Glucose-6-phosphate dehydrogenase (G6PD) is unique in th

124 The lipogenic enzyme glucose-6-phosphate dehydrogenase (G6PD) is unique in th

125 Glucose-6-phosphate dehydrogenase (G6PD) modulates vascu

126 Glucose-6-phosphate dehydrogenase (G6PD) mutations that

127 hrough microscopy and had normal function of glucose-6-phosphate dehydrogenase (G6PD) on colorimetric

128 , which was exacerbated in erythrocytes from glucose-6-phosphate dehydrogenase (G6PD) patients and re

129 Glucose-6-phosphate dehydrogenase (G6PD) plays an essent

130 Glucose-6-phosphate dehydrogenase (G6PD) regulates produ

131 Glucose-6-phosphate dehydrogenase (G6PD) status was dete

132 In vivo, pharmacological inhibition of glucose-6-phosphate dehydrogenase (G6PD) to decrease NAD

133 t of reductive capacity by overexpression of glucose-6-phosphate dehydrogenase (G6PD), a key enzyme f

134 y (PPP) is necessary for NET release because glucose-6-phosphate dehydrogenase (G6PD), an important e

135 Glucose-6-phosphate dehydrogenase (G6PD), encoded by zwf

136 ented expression and enzymatic activities of glucose-6-phosphate dehydrogenase (G6PD), glutathione re

137 ene expression of GLUT1 glucose transporter, glucose-6-phosphate dehydrogenase (G6PD), superoxide dis

138 Glucose-6-phosphate dehydrogenase (G6PD), the first enzy

139 the bacterial pathogen Pseudomonas syringae Glucose-6-phosphate dehydrogenase (G6PD), the key enzyme

140 Glucose-6-phosphate dehydrogenase (G6PD), the rate-limit

141 Glucose-6-phosphate dehydrogenase (G6PD), the rate-limit

142 ose phosphate pathway through the actions of glucose-6-phosphate dehydrogenase (G6PD), the rate-limit

143 Here we show that glucose-6-phosphate dehydrogenase (G6PD), the rate-limit

144 the activity of another cytoplasmic enzyme, glucose-6-phosphate dehydrogenase (G6PD), was also measu

145 The gene encoding glucose-6-phosphate dehydrogenase (G6PD), zwf, in Nostoc

146 ne deacetylase (HDAC) inhibitors (HDACis) in glucose-6-phosphate dehydrogenase (G6PD)-deficient cells

147 he rate-limiting enzyme in NADPH production, glucose-6-phosphate dehydrogenase (G6PD).

148 creened for those VHbinding sites that bound glucose-6-phosphate dehydrogenase (G6PD).

149 In addition, glucose-6-phosphate-dehydrogenase (G6PD) deficiency, whi

150 haemolysis in patients with a deficiency in glucose-6-phosphate dehydrogenase (G6PDd).

151 lucose uptake with a concomitant increase in glucose-6-phosphate dehydrogenase (G6PDH) activity, the

152 eveloped by using a coupled enzyme system of glucose-6-phosphate dehydrogenase (G6PDH) and bacterial

153 investigated the reactivation of aggregated glucose-6-phosphate dehydrogenase (G6PDH) by ClpB and it

154 Glucose-6-phosphate dehydrogenase (G6PDH) controls the f

155 Glucose-6-phosphate dehydrogenase (G6PDH) has been impli

156 Interestingly, three eukaryotic glucose-6-phosphate dehydrogenase (G6PDH) isozymes, from

157 toxification enzymes such as NQO1 as well as glucose-6-phosphate dehydrogenase (G6PDH), a regulator o

158 he Pseudomonas aeruginosa zwf gene, encoding glucose-6-phosphate dehydrogenase (G6PDH), an enzyme tha

159 linked isocitrate dehydrogenase (NADP-ICDH), glucose-6-phosphate dehydrogenase (G6PDH), and, glutathi

160 showed here that a mutation in zwf, encoding glucose-6-phosphate dehydrogenase (G6PDH), leads to a ap

161 first and committed reaction is catalyzed by glucose-6-phosphate dehydrogenase (G6PDH).

162 g PEPCK, glucose-6-phosphatase (G6Pase), and glucose-6-phosphate dehydrogenase (G6PDHase).

163 Mutants defective in the putative glucose-6-phosphate dehydrogenase gene (zwf-) and the al

164 We studied the contribution of glucose-6-phosphate dehydrogenase (Glc-6-PD), an importa

165 athione (GSH), glutathione peroxidase (GPX), glucose 6-phosphate dehydrogenase, glutathione reductase

166 ant enzymes including alcohol dehydrogenase, glucose 6-phosphate dehydrogenase, glycerol 3-phosphate

167 ontinuous assay, using glucokinase (Glk) and glucose-6-phosphate dehydrogenase (Gpd) from Thermotoga

168 It is based on the glucose-6-phosphate dehydrogenase (Gpdh) and 6-phosphogl

169 Glucose-6-phosphate dehydrogenase, GSH S-transferase, an

170 viously studies using X-linked genes such as glucose-6-phosphate dehydrogenase have been handicapped

171 sis of autologous transplantation studies in glucose-6-phosphate dehydrogenase heterozygous cats to d

172 th respect to the human housekeeping enzyme, glucose 6-phosphate dehydrogenase (hG6PD).

173 Here we report point mutations in the human glucose-6-phosphate dehydrogenase (hG6PD) gene transferr

174 The frequencies of low-activity alleles of glucose-6-phosphate dehydrogenase in humans are highly c

175 hibition of the pentose phosphate pathway by glucose-6-phosphate dehydrogenase inhibitors and siRNA s

176 e of the bacterial Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase, it has been possible

177 , mRNAs for several other lipogenic enzymes (glucose-6-phosphate dehydrogenase, malic enzyme, glycero

178 mino acid changes on to the structure of the glucose-6-phosphate dehydrogenase molecule.

179 strate and coenzyme binding and catalysis of glucose-6-phosphate dehydrogenase of Leuconostoc mesente

180 e did not observe changes in the activity of glucose-6-phosphate dehydrogenase or in the pentose phos

181 stroy the tissues to study the haplotypes of glucose-6-phosphate dehydrogenase or to determine the re

182 Plasmodium falciparum glucose 6-phosphate dehydrogenase (Pf Glc6PD), compared

183 compounds that inhibit Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PD).

184 ococcal mutants deficient in PavA, CodY, and glucose-6-phosphate dehydrogenase pointing to the robust

185 mologs of 6-phosphogluconate dehydratase and glucose-6-phosphate dehydrogenase, respectively.

186 ependence of the kinetic parameters of D177N glucose 6-phosphate dehydrogenase results from an ionize

187 METHODS AND Patients with normal glucose-6-phosphate dehydrogenase status with symptomati

188 eveloped by utilizing a "wired" thermostable glucose-6-phosphate dehydrogenase (tG6PDH) from the hype

189 Mycobacterium smegmatis was found to have a glucose-6-phosphate dehydrogenase that was dependent on

190 ibrosis transmembrane conductance regulator, glucose-6-phosphate dehydrogenase, the neural cell adhes

191 -1 but no changes in glutathione peroxidase, glucose-6-phosphate dehydrogenase, thiols, or catalase.

192 ecific inhibitor (dehydroepiandrosterone) of glucose-6-phosphate dehydrogenase together established r

193 nternal control was shown by comparison with glucose-6-phosphate dehydrogenase transcript levels in 1

194 ydrodiol dehydrogenase, apolipoprotein J and glucose-6-phosphate dehydrogenase variant-A.

195 The three-dimensional structure of the H240N glucose 6-phosphate dehydrogenase was determined at 2.5

196 smutase 1, glutathione S-transferase-pi, and glucose-6-phosphate dehydrogenase was unaffected by cast

197 peroxidase, NADH/NADP+ transhydrogenase, and glucose-6-phosphate dehydrogenase were most strongly ind

198 of the cytosolic isocitrate dehydrogenase or glucose-6-phosphate dehydrogenase, which also produce cy

199 ersensitivity to SFK2 yielded ZWF1, encoding glucose-6-phosphate dehydrogenase, which has been shown

200 strain over-expressing zwf gene (coding for glucose-6-phosphate dehydrogenase), WX-zwf, produced the

201 own previously to require function of either glucose-6-phosphate dehydrogenase (ZWF1) or cytosolic NA

202 ted an investigation of mutants defective in glucose-6-phosphate dehydrogenase (Zwf1), which catalyze

203 ells grown on glucose has been attributed to glucose-6-phosphate dehydrogenase (Zwf1p) and a cytosoli

204 trate dehydrogenase and in the gene encoding glucose-6-phosphate dehydrogenase (Zwf1p).