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1 nts that synthesize phytoalexins from indole glucosinolate.
2 tissue of a mouse orally treated with 1-MIM glucosinolate.
3 dure for determination and quantification of glucosinolates.
4 no acid-derived secondary metabolites called glucosinolates.
5 vage also contributes to the biosynthesis of glucosinolates.
6 teps towards the biosynthesis of Met-derived glucosinolates.
7 pathways, such as the degradation of indole glucosinolates.
8 vegetables containing high concentrations of glucosinolates.
9 p accumulated different types and amounts of glucosinolates.
10 ly altered the accumulation of the defensive glucosinolates.
11 stance transport of aliphatic but not indole glucosinolates.
12 are able to synthesize aliphatic and indole glucosinolates.
13 synthesis of sulfated secondary metabolites, glucosinolates.
14 ne, as well as a differential composition of glucosinolates.
15 uts with enhanced levels of health-promoting glucosinolates.
16 yanates derived from nutritionally important glucosinolates.
17 localized elevation of indole and aliphatic glucosinolates.
19 PCA allowed us to identify a big cluster of glucosinolates (10 out 15 tested) that do not possess an
21 at biosynthesis of 1-methoxyindol-3-ylmethyl glucosinolate (1MOI3M) from I3M involves the predicted u
22 table intermediate 1-hydroxyindol-3-ylmethyl glucosinolate (1OHI3M) and that IGMT5, a gene with moder
23 ignaling properties specific to one distinct glucosinolate, 3-hydroxypropylglucosinolate across plant
24 activation of myrosinase and preservation of glucosinolate (85% of the untreated level) was obtained
25 e-escalation in the numbers and diversity of glucosinolates, accompanied by an evolutionary increase
27 d on our results, we propose a model for how glucosinolates accumulate in the leaf margin and epiderm
28 absence of GTR1 and GTR2 transport activity, glucosinolates accumulate predominantly in leaf margins
31 mutational analysis identified residues for glucosinolate aglucone and Fe(2+) cofactor binding withi
32 an active site and docking arrangements with glucosinolate aglucones that may explain some of the dif
33 lates in Arabidopsis, also play key roles in glucosinolate allocation within a mature leaf by effecti
36 sms of defense metabolite signaling, we used glucosinolates, an important class of plant defense meta
37 thaliana Columbia metabolism, which adds the glucosinolates, an important group of secondary metaboli
38 mass spectrometry (LC-MS) was used to obtain glucosinolate and flavonol content for 35 rocket accessi
40 ce in B. juncea has facilitated selection of glucosinolate and lipid metabolism genes in subvarieties
41 fy industrial broccoli by-products for their glucosinolate and polyphenol contents as a first step to
43 this study was to determine the polyphenols, glucosinolates and ascorbic acid content as well as anti
44 ver, the concentration of tryptophan-derived glucosinolates and auxin were reduced in PGDH1-silenced
47 vironment conditions on the accumulations of glucosinolates and flavonols and explore the reasons for
48 es C for 13 min; coinciding with the minimum glucosinolates and glucoraphanin content, and with the m
49 published evidence proving the link between glucosinolates and growth, this is likely a false negati
50 f the new germplasm with reduced detrimental glucosinolates and increased beneficial glucosinolates f
53 s risen as rich in bioactive phytochemicals (glucosinolates and phenolic compounds) closely linked wi
55 opsis thaliana) seeds, including benzoylated glucosinolates and substituted hydroxybenzoylcholines.
57 ried out on the influence of fermentation on glucosinolates and their degradation products from fresh
60 Also for the insect S. exigua, the indolic glucosinolates appeared to play a role in the Pf.SS101-i
64 ondary metabolites showed that camalexin and glucosinolates are indeed required for the induction of
65 cosinolates decreased, suggesting that these glucosinolates are less involved in the plants' response
66 se findings provide deeper insights into how glucosinolates are metabolized in cruciferous plants and
68 hatic glucosinolates, long-chained aliphatic glucosinolates are synthesized both in roots and rosette
71 ic acid signaling and biosynthesis of indole glucosinolates, are central to Arabidopsis's defense to
72 Due to the instability of intact Moringa glucosinolates at room temperature and during the purifi
73 be involved in bidirectional distribution of glucosinolates between the roots and rosettes, indicatin
74 mutation in CYP83B1 and displays defects in glucosinolate biosynthesis and in phenylpropanoid accumu
75 part of a regulatory feed-back loop linking glucosinolate biosynthesis and JA signaling and thereby
76 ic roles in sulfur transport and metabolism, glucosinolate biosynthesis and trehalose metabolism.
78 that IPMDH-like enzymes in both leucine and glucosinolate biosynthesis pathways use a common mechani
79 acids in the leucine- and methionine-derived glucosinolate biosynthesis pathways, respectively, in pl
80 nolate metabolism, perturbation of aliphatic glucosinolate biosynthesis was established using inducib
81 ormone signaling pathways, defense response, glucosinolate biosynthesis, cell wall modification, suga
87 een ER body-related genes (including PYK10), glucosinolate biosynthetic genes and the genes for so-ca
90 RT-PCR based expression analysis of seven glucosinolate biosynthetic pathway genes (MYB28, CYP79F1
92 While the toxic and deterrent effects of glucosinolate breakdown on herbivores and pathogens have
93 enables more detailed mechanistic studies on glucosinolate breakdown product formation, but also prov
96 rimental investigations of the mechanisms of glucosinolate breakdown that will also help to better un
97 ced on cyp79B2 cyp79B3 hosts (without indole glucosinolates) but inhibited on atr1D hosts (with eleva
100 y studied the in vitro redox behaviour of 15 glucosinolates, by using a range of analytical methods m
102 er showed that triterpenoid biosynthetic and glucosinolate catabolic genes are up-regulated in jazQ i
104 ter specificity towards the recently evolved glucosinolates characteristic of Brassicales is shown to
105 ound weak to moderate phylogenetic signal in glucosinolate classes and no signal in total glucosinola
107 t of pressure level, temperature and time on glucosinolate concentration and myrosinase activity in B
108 s on residual myrosinase activity and intact glucosinolate concentration differed according to combin
109 F oven preserved ascorbic acid and increased glucosinolates concentration in broccoli and it decrease
110 ent CO2, leaf nitrogen had strong effects on glucosinolate concentrations and P. rapae consumption bu
111 rtility and damage (simulated herbivory), on glucosinolate concentrations of mustard (Brassica nigra)
114 The obtained beverages were characterized glucosinolates content at 117.6-167.6mg/L and ascorbic a
115 eatments could enhance effectively the total glucosinolates content in the sprouts, achieving the mos
116 of seeds as a novel strategy to trigger the glucosinolates content was carried out with water (contr
121 sugars, 9mg/mL amino acids, and 356microg/mL glucosinolates, depending on the type of by-product used
129 lism and laid a foundation towards rationale glucosinolate engineering for enhanced defense and quali
131 period and cold acclimatisation on levels of glucosinolates, fatty acids and soluble sugars in kale,
132 w through leaf apoplastic fluid analysis and glucosinolate feeding experiments that two glucosinolate
133 eral classes of phytochemicals (isoflavones, glucosinolates, flavones, flavonols and phenolic acids)
136 ntal glucosinolates and increased beneficial glucosinolates for producing improved brassica vegetable
137 and activation of tryptophan-derived indole glucosinolates for subsequent PEN3-mediated efflux acros
139 ng hosts (wild type and atr1D) compared with glucosinolate-free hosts (cyp79B2 cyp79B3 myb28 myb29).
140 was actually reduced on dodder parasitizing glucosinolate-free hosts compared with wild-type or atr1
141 r, the desulfation step in the extraction of glucosinolates from Moringa oleifera leaves resulted in
143 t P. striolata adults selectively accumulate glucosinolates from their food plants to up to 1.75% of
144 us oilseed types has accelerated the loss of glucosinolate genes, while preserving expansion of oil b
145 y illustrates the translation of research on glucosinolate genetics from Arabidopsis to broccoli, the
147 as raw vegetables provides a fair amount of glucosinolates (GLs) and active plant myrosinase, which
148 ate the effect of storage on the contents of glucosinolates (GLS) and their degradation products in a
149 ycoalkaloids, flavonoids, organic acids, and glucosinolates (GLs) are detected in the target regions
151 oncentrations of sensory relevant compounds: glucosinolates (GLSs), flavonoid glycosides, hydroxycinn
152 Decreasing contents were observed for the glucosinolates glucobrassicin and 4-methoxyglucobrassici
153 iocyanate (92.06%), a degradation product of glucosinolate glucocapparin, was detected as major compo
154 ped and validated to determine twelve intact glucosinolates (glucoiberin, GIB; glucoraphanin, GRA; gl
156 trin was reduced by 65 %, and the beneficial glucosinolate glucoraphanin was increased to a relativel
157 in water (5-15 min) on the content of total glucosinolates, glucoraphanin, sulforaphane, and myrosin
158 ected ITCs in the synovial fluid of the high glucosinolate group, but not the low glucosinolate group
160 ephala) and the effects of leaf nitrogen and glucosinolate groups on specialist Pieris rapae consumpt
161 three field trials, we quantified aliphatic glucosinolate (GSL) defense chemistry, leaf damage, and
162 he Arabidopsis thaliana defensive compounds, glucosinolates (GSL) control field fitness and are there
165 alibration to determine individual and total glucosinolates (GSLs) content of 12 new-bred open-pollin
166 rtner of MYB51, the key regulator of indolic glucosinolates (GSLs) in Arabidopsis (Arabidopsis thalia
168 ct effects of leaf nitrogen were weaker, but glucosinolates had stronger effects on consumption.
169 opsis, accumulation of the defense compounds glucosinolates has previously been linked to genetic var
171 metabolites such as alkaloids, terpenes, and glucosinolates have been studied extensively, the fitnes
173 ontent, antioxidant activity and recoverable glucosinolates, however it increases the carotenoid conc
174 ygenase pathway (mainly C6-aldehydes) and of glucosinolate hydrolysis (mainly isothiocyanates), and t
175 utane, are important, but yet underestimated glucosinolate hydrolysis products that are released inst
178 iana) IG core biosynthesis, indol-3-ylmethyl glucosinolate (I3M), can be modified by hydroxylation an
179 (ER) body formation and induction of indole glucosinolate (IGs) metabolism selectively, via transcri
181 . thaliana root ER bodies, hydrolyzes indole glucosinolates (IGs) in addition to the previously repor
182 upled with the activity of putative vacuolar glucosinolate importers in these peripheral cell layers.
185 t proof of the existence of a 5-phenylpentyl glucosinolate in the aerial parts of this species as one
187 R2, essential for long-distance transport of glucosinolates in Arabidopsis, also play key roles in gl
188 , combined with varying sulfur (S) supply on glucosinolates in Brassica juncea in order to reveal whe
192 il drying initiated an increase in aliphatic glucosinolates in leaves and in topsoil dried roots supp
193 relationship between accumulation of Se and glucosinolates in mature Brassica plants, Se supply gene
195 R2), which are essential for accumulation of glucosinolates in seeds, are likely to also be involved
196 t the rate-limiting steps in biosynthesis of glucosinolates in the root are oxidative modifications o
199 drying may already lead to a drought-induced glucosinolate increase promoted by an enhanced S supply.
200 serpentine soil use; and that the number of glucosinolates increases with microhabitat bareness, whi
201 cabbage suggesting their non-involvement in glucosinolate induction during radiation processing.
202 jasmonates, signalling molecules involved in glucosinolate induction was, however, unaffected in irra
203 nd during the purification process of single glucosinolates, influences of different storage (room te
205 issue damage caused by insect feeding brings glucosinolates into contact with the plant enzyme myrosi
206 he drought-induced accumulation of aliphatic glucosinolates is related to abscisic acid formation.
208 and acetyl-4-alpha-rhamnopyranosyloxy-benzyl glucosinolate isomers (Ac-Isomers-GS) during HPLC analys
209 vealed strong, positive correlations between glucosinolates, isothiocyanates and sulfur compounds wit
212 We detected a significant contribution of glucosinolate loci toward general herbivore resistance a
213 and storage site for short-chained aliphatic glucosinolates, long-chained aliphatic glucosinolates ar
215 hat diets rich in cruciferous vegetables and glucosinolates may reduce the risk of cancer and cardiov
216 recedented view of the molecular networks of glucosinolate metabolism and laid a foundation towards r
219 the terminal products of myrosinase-mediated glucosinolate metabolism, indicating that these systems
220 To understand plant molecular networks of glucosinolate metabolism, perturbation of aliphatic gluc
223 that can alter accumulation of the defensive glucosinolate metabolites in Arabidopsis (Arabidopsis th
224 To date the common DIN extraction 'desulfo glucosinolates' method remains the common procedure for
228 lants (Brassicales) that are defended by the glucosinolate-myrosinase system, the so-called "mustard-
229 andard mutagenicity tests treated with 1-MIM glucosinolate/myrosinase as well as in 1-MIM alcohol-tre
230 related to Arabidopsis thaliana, synthesizes glucosinolates, nitrogen- and sulfur-containing secondar
231 450 monooxygenases and IGMTs encoding indole glucosinolate O-methyltransferases have been identified
232 rradiation also enhanced sinigrin, the major glucosinolate of cabbage that accounted for the enhanced
235 dels independent of the test compound (1-MIM glucosinolate or alcohol), whereas dA adducts predominat
236 ced changes in secondary metabolites such as glucosinolates or flavonoids were detected in cml37 plan
242 tified, with the most prominent groups being glucosinolates, phenylpropanoids, and dipeptides, the la
243 s) are one of several hydrolysis products of glucosinolates, plant secondary metabolites that are sub
244 e, a dietary isothiocyanate derived from its glucosinolate precursor which is found in broccoli, can
248 educed significantly when dodder parasitized glucosinolate-producing hosts (wild type and atr1D) comp
249 glucosinolate classes and no signal in total glucosinolate production; a trend toward evolutionary de
251 ition to demonstrating the adaptive value of glucosinolate profile variation, we also detected long-d
252 36% of among accession variation in overall glucosinolate profile was explained by genetic different
254 r suggest that the distinct rosette and root glucosinolate profiles in Arabidopsis are shaped by long
256 ted phylogenetically explicit analyses using glucosinolate profiles, soil nutrient analyses, and micr
257 the genetics underlying natural variation in glucosinolate profiles, we conducted a large genome-wide
259 eady changed in the presenescent leaves, and glucosinolates, raffinose, and galactinol accumulated in
262 hibited on atr1D hosts (with elevated indole glucosinolates) relative to wild-type hosts, which respo
264 both analytical methods and that the tested glucosinolates respond similarly to both Michaelis-Mente
265 ed CO2 affected B. oleracea but not B. nigra glucosinolates; responses to soil fertility and damage w
266 stabilize 4-alpha-rhamnopyranosyloxy-benzyl glucosinolate (Rhamno-Benzyl-GS) and acetyl-4-alpha-rham
267 antioxidant capacity; while, the other five glucosinolates showed moderate and specific antioxidant
268 instead of isothiocyanates depending on the glucosinolate side chain structure and the type of speci
269 nary increase in the proportion of aliphatic glucosinolates; some support for the RAH relative to soi
270 showing a dramatic reduction of Met-derived glucosinolate species down to 32 and 14% of wild-type le
271 ication, on antioxidant capacity, phenolics, glucosinolates, sulphoraphane, Se-methyl selenocysteine
277 e-dependent conversion of select non-natural glucosinolates to non-natural ITCs cannot be accomplishe
280 d glucosinolate feeding experiments that two glucosinolate transporters, GTR1 and GTR2, essential for
281 ivo feeding experiments demonstrate that the glucosinolate transporters1 and 2 (GTR1 and GTR2), which
282 the novel feeding deterrent effect of indole glucosinolates under elevated CO2 in B. oleracae undersc
283 e association study of 22 methionine-derived glucosinolates using A. thaliana accessions from across
284 d not vary, while the response of individual glucosinolates varied with temperature and day length, a
286 a significant increase of total and specific glucosinolates, vitamin C, total anthocyanins and polyph
287 e, a method for extraction of intact Moringa glucosinolates was developed and no conversion and degra
289 ds, the benzylisoquinoline alkaloids and the glucosinolates--was made possible through the characteri
292 acids, isoflavones, flavones, flavonols and glucosinolates were determined in fresh and fresh-cut sa
296 ominantly glucoraphanin (32-64% of the total glucosinolates), whereas the polyphenolic content was le
297 logously expressed myrosinase were aliphatic glucosinolates, which were hydrolyzed with at least four
298 e complete kinetic characterization of three glucosinolates with Sinapis alba myrosinase, with result
300 e breakage in cells harboring myrosinase and glucosinolate yields a brew toxic to many animals, espec
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