ライフサイエンスコーパス: glucuronic

1 n to grow with N-acetylglucosamine but not d-glucuronic acid (both components of HA) as a sole carbon

2 ol g(-1)), whereas binding of the competitor glucuronic acid (GA) and other monosaccharides was consi

3 formation occurs by the copolymerization of glucuronic acid (GlcA) and N-acetylglucosamine (GlcNAc)

4 lcNAc) or N-sulfated glucosamine (GlcNS) and glucuronic acid (GlcA) as the primary sites and the link

5 uishing the epimers iduronic acid (IdoA) and glucuronic acid (GlcA) has been a long-standing challeng

6 corporation of radioactive glucose (Glc) and glucuronic acid (GlcA) into lipid-linked disaccharides i

7 ore-shell particles specifically recognizing glucuronic acid (GlcA) or N-acetylneuraminic acid (NANA)

8 glycan decorations that include a conserved glucuronic acid (GlcA) residue and various additional su

9 ries a pentose linked 1-2 to the alpha-1,2-d-glucuronic acid (GlcA) side chains on the beta-1,4-Xyl b

10 ta-glucuronidase (GUS) enzymes that liberate glucuronic acid (GlcA) sugars from small-molecule conjug

11 the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within HS.

12 MIPs were prepared with the templates D-glucuronic acid (GlcA), a substructure of hyaluronan, an

13 The distribution of 13C in the Man, Xyl, glucuronic acid (GlcA), and O-acetyl constituents of nat

14 merase (Hsepi) catalyzes C5-epimerization of glucuronic acid (GlcA), converting it to iduronic acid (

15 residues substituted with alpha(1,2)-linked glucuronic acid (GlcA).

16 Glucuronic acid (GlcAp) and/or methylglucuronic acid (Me

17 is a membrane-bound enzyme that utilizes UDP-glucuronic acid (GlcUA) and UDP-GlcNAc to synthesize HA.

18 at transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA) in alternative positions in the

19 sed of alternating beta-1,3-Glc and beta-1,4-glucuronic acid (GlcUA) linkages.

20 atalyzes sugar transfer from UDP-Glc and UDP-glucuronic acid (GlcUA) to a polymer with the repeating

21 yltransferase that catalyzes the transfer of glucuronic acid (GlcUA) to the common growing linker reg

22 s comprising 3-sulfated rhamnose linked to d-glucuronic acid (GlcUA), l-iduronic acid (IdoUA), or d-x

23 PmHAS possesses both GlcNAc-transferase and glucuronic acid (GlcUA)-transferase activities.

24 -ribofuranose and 3-O-[(R)-1-carboxyethyl]-D-glucuronic acid (nosturonic acid) pendant groups.

25 highly sulfated polysaccharide consisting of glucuronic acid (or iduronic acid) linked to glucosamine

26 ctivity against hyaluronan (HA), poly-beta-d-glucuronic acid (poly-GlcUA), and poly-beta-d-mannuronic

27 ) to the key metabolic precursor UDP-alpha-d-glucuronic acid (UDP-GlcA) and display specificity for U

28 e authentic sugar nucleotide precursors, UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylglucosamine (

29 together with UDP-xylose is formed from UDP-glucuronic acid (UDP-GlcA) by UDP-Api synthase (UAS).

30 The biosynthesis of UDP-Xyl from UDP-glucuronic acid (UDP-GlcA) is irreversibly catalyzed by

31 UDP-glucuronic acid (UDP-GlcA) is the precursor of many plan

32 ing (1) the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcA) to the UDP-4' '-ketopentose [

33 ) catalyzes the epimerization of UDP-alpha-D-glucuronic acid (UDP-GlcA) to UDP-alpha-D-galacturonic a

34 is synthesized by the decarboxylation of UDP-glucuronic acid (UDP-GlcA).

35 nverts UDP-2-acetamido-3-amino-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NA) to UDP-2,3-diacetamido-2

36 NAc3NA) to UDP-2,3-diacetamido-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NAcA).

37 ed nucleotide sugars UDP-2-acetamido-2-deoxy-glucuronic acid (UDP-GlcNAcA) and UDP-2-acetamido-2-deox

38 te (Glc-6-P) --> Glc-1-P --> UDP-Glc --> UDP-glucuronic acid (UDP-GlcUA) --> (GlcUA-Glc)(n).

39 accharide units from the donor molecules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine

40 oniae requires UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3)-be

41 resence of protein-mediated transport of UDP-glucuronic acid (UDP-GlcUA) in rat liver endoplasmic ret

42 lcUA-(1-] from UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) is catalysed by the type 3 s

43 nic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region

44 trate for all glucuronidation reactions, UDP-glucuronic acid (UDP-GlcUA), was determined using a rapi

45 applied to develop a synthesis of protected glucuronic acid 1, a key intermediate in the synthesis o

46 ed a rare sequence consisting of consecutive glucuronic acid 2-O-sulfate residues as selectively targ

47 boring nodes of Ranvier stained for unmasked glucuronic acid 3-SO4 and chondroitin 6-SO4.

48 ies against carbohydrate epitopes, including glucuronic acid 3-SO4 and chondroitins 6-SO4 and 4-SO4.

49 inant UAS homologs all form UDP-Api from UDP-glucuronic acid albeit in different amounts.

50 Mutations in a previously identified UDP-glucuronic acid allosteric binding site decreased the bi

51 shown to hydrolyze terminal alpha-1,2-linked glucuronic acid and 4-O-methylated glucuronic acid from

52 backbone of xylosyl residues substituted by glucuronic acid and 4-O-methylglucuronic acid (collectiv

53 that although wild-type xylans contain both glucuronic acid and 4-O-methylglucuronic acid residues,

54 ranosiduronic acids (glucuronides) using UDP-glucuronic acid and acceptor substrates such as drugs, s

55 lation, we identified O-acetylation of alpha-glucuronic acid and alpha-glucose in 9A PS.

56 es with low ratios of xylose to 4-O-methyl-D-glucuronic acid and appears to require two 4-O-methyl-D-

57 in itself, and this binding was inhibited by glucuronic acid and chondroitin sulfate.

58 hesized in the assay was composed of Glc and glucuronic acid and could be degraded to a low molecular

59 dependent oxidation of the 4''-OH of the UDP-glucuronic acid and decarboxylation of the UDP-4-keto-gl

60 f acidic O-linked glycoconjugates containing glucuronic acid and galactose as well as a reduction of

61 microfibrils had a higher content of (methyl)glucuronic acid and galactose in tension wood than in no

62 dation of not only alginate, but poly-beta-D-glucuronic acid and hyaluronic acid as well.

63 o its ability to sequester intracellular UDP-glucuronic acid and inhibition of hyaluronan synthase tr

64 tabolites; quercetin-3'-sulfate, quercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were

65 ed that the resulting mutant lacked both UDP-glucuronic acid and its downstream product, UDP-xylose,

66 ible for the oxidation of UDP-glucose to UDP-glucuronic acid and its subsequent decarboxylation to UD

67 accommodation of alpha1,2-linked 4-methyl-D-glucuronic acid and L-arabinofuranose side chains.

68 ase responsible for the interconversion of d-glucuronic acid and l-iduronic acid residues encodes a t

69 DG42 encoded on a plasmid incorporated [14C]glucuronic acid and N-[3H]acetylglucosamine from exogeno

70 ide composed of repeating disaccharides of D-glucuronic acid and N-acetyl-D-glucosamine (GlcNAc).

71 nctional chondroitin synthase K4CP catalyzes glucuronic acid and N-acetylgalactosamine transfer activ

72 block, and the two monosaccharide components glucuronic acid and N-acetylglucosamine and identify mar

73 ted HA synthase capable of transferring both glucuronic acid and N-acetylglucosamine groups.

74 long linear polymer composed of alternating glucuronic acid and N-acetylglucosamine residues, is an

75 inear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues, is an

76 onsisting of repeating disaccharide units of glucuronic acid and N-acetylglucosamine.

77 reaction of appropriately substituted azido-glucuronic acid and propargyluted N-acetyl glucosamine a

78 and two quercetin metabolites (quercetin-3-O-glucuronic acid and quercetin-3-O-sulfate) significantly

79 e propose a binding model for NAD(+) and UDP-glucuronic acid and the involvement of residues T(432),

80 catalyzes the conjugation of bilirubin with glucuronic acid and thus enhances bilirubin elimination;

81 eds in three chemical steps via UDP-4-keto-D-glucuronic acid and UDP-4-keto-pentose intermediates.

82 UXNAcS is specific and cannot utilize UDP-glucuronic acid and UDP-galacturonic acid as substrates.

83 at synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as well as

84 ynthases (HAS1-3), which use cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as substrate

85 s beta-glucuronidase enzymes that remove the glucuronic acid as a carbon source, effectively reversin

86 by the ORF atu2297, with UDP-glucose or UDP-glucuronic acid as sugar donors.

87 A Cer analogue with a D-glucuronic acid attached at the primary hydroxyl of N-pa

88 magnetic resonance studies confirmed that a glucuronic acid beta1,4-xylose disaccharide synthesized

89 resolution apo crystal structure of the UDP-glucuronic acid binding domain of human UGT isoform 2B7

90 ncoded protein is closely related to the UDP-glucuronic acid binding site consensus sequence, and the

91 A calcium-dependent glucuronic acid binding site shows distinctive structura

92 The deletion of either sequence abolishes glucuronic acid but not N-acetylgalactosamine transfer a

93 ectins, is produced from the precursor UDP-D-glucuronic acid by the action of glucuronate 4-epimerase

94 Biosynthesis of UDP-glucuronic acid by UDP-glucose 6-dehydrogenase (UGDH) oc

95 scovered that the published sequence for the glucuronic acid C5-epimerase responsible for the interco

96 t has an overall 37% homology to the human D-glucuronic acid C5-epimerase.

97 residues predicted to interact with the UDP-glucuronic acid cofactor exhibited significantly impaire

98 Compound 5e was converted to beta-glucuronic acid conjugate 6e by the action of pig liver

99 or each analyte; a mixture of 1-pyOH and its glucuronic acid conjugate can be analyzed in 30 min.

100 nantly excreted (>87%) in human urine as the glucuronic acid conjugate, whereas the relative abundanc

101 Minor compounds were glucuronic acid conjugates of 9,10-dihydroxy-octadecanoi

102 iver, intestine and kidney, and catalyze the glucuronic acid conjugation of both endogenous compounds

103 recombinant human UGT isoforms, we show that glucuronic acid conjugation of the model substrate, (-)-

104 (UDP-GlcA) is irreversibly catalyzed by UDP-glucuronic acid decarboxylase (UXS).

105 iosynthesis of UDP-xylose is mediated by UDP-glucuronic acid decarboxylase, which converts UDP-glucur

106 ransmembrane protein that functions as a UDP-glucuronic acid decarboxylase.

107 coccal sequence as putatively encoding a UDP-glucuronic acid decarboxylase.

108 Acetate or glucuronic acid decorations are exclusively found on eve

109 uronic acid degradation at pH 5, poly-beta-D-glucuronic acid degradation at pH 7, and alginate degrad

110 ndogenous and exogenous chemicals by linking glucuronic acid donated by UDP-glucuronic acid to a lipo

111 o glycoside (25) with a trichloroacetimidate glucuronic acid donor (13), using a catalytic amount of

112 The Glc-GlcA disaccharide, featuring the glucuronic acid donor moiety, proved to be the most prod

113 We demonstrated that lpsL encoded a UDP-glucuronic acid epimerase activity that was reduced in t

114 a gene previously predicted to encode a UDP-glucuronic acid epimerase.

115 espect to chain length, sulfate content, and glucuronic acid epimerization content, resulting in a di

116 Although glucuronic acid esters are often considered to be of ver

117 eactions revealed that the reactivity of the glucuronic acid esters studied is sufficient to provide

118 The relative reactivity of glucuronic acid esters was established in a series of co

119 ,2-linked glucuronic acid and 4-O-methylated glucuronic acid from the plant cell wall polysaccharide

120 6OSO3), but contained a higher proportion of glucuronic acid GlcUA-GlcNSO3(6OSO3) and IdUA-GlcNSO3(6O

121 Reaction of beta-glucuronic acid glycoside of 4-hydroxy-3-nitrobenzyl alc

122 ogether with the aglycon and alpha- and beta-glucuronic acid hydrolysis products.

123 may be close to the 3-hydroxyl group of beta-glucuronic acid in a HNK-1 acceptor.

124 esonance that revealed a crucial role of the glucuronic acid in antibody binding.

125 w that the carboxyl group on nonreducing end glucuronic acid in dodecasaccharide motif is important f

126 o distinguish the epimers iduronic acid from glucuronic acid in heparan sulfate tetrasaccharides and

127 a1-4 linkage between N-acetylglucosamine and glucuronic acid in hyaluronan polymers via a substrate-a

128 s undergo detoxification by conjugation with glucuronic acid in the liver via the action of UDP-glucu

129 Nrf2 promoted conjugation of ABP with glucuronic acid in the liver, increasing urinary excreti

130 n, ideal for decarboxylation of UDP-4-keto-D-glucuronic acid in the second chemical step.

131 E, quercetin-3-O-glucoside and quercetin-3-O-glucuronic acid inhibited significantly (p<0.05) ACE act

132 c acid and decarboxylation of the UDP-4-keto-glucuronic acid intermediate.

133 The oxidative decarboxylation of UDP-glucuronic acid is catalyzed by the 345-residue C-termin

134 d-Glucuronic acid is further metabolized to xylitol via th

135 ctivity of B3GAT1, we were able to show that glucuronic acid is present on antennae of plasma glycopr

136 In humans, conjugation with glucuronic acid is the most important phase II metabolic

137 In mammalian organisms, UDP-glucuronic acid is typically used in the transfer reacti

138 at is specific for the l-rhamnose-alpha1,4-d-glucuronic acid linkage that caps the side chains of com

139 Glucuronic acid linked prodrugs of O(6)-benzylguanine an

140 ated Az29, possesses two PEtn moieties and a glucuronic acid linked to a Gal-extended Nz28.

141 ranched surface structure containing glucose-glucuronic acid linked to a glucose-rhamnose-rhamnose-rh

142 vered that heparanase cleaves the linkage of glucuronic acid linked to glucosamine carrying 6-O-sulfo

143 Glucuronic acid modification was observed in E. coli B,

144 f sugar residues and epimerizations of their glucuronic acid moieties.

145 etraazacyclododecane) bearing a pendant beta-glucuronic acid moiety connected by a self-immolative li

146 GlcAT-I transfers a glucuronic acid moiety from the uridine diphosphate-gluc

147 cid hydrolysis, resulting in a Xyl:arabinose:glucuronic acid molar ratio of approximately 105:34:1.

148 scribed, which arises due to the addition of glucuronic acid on the third heptose with a concomitant

149 transferase GUX1, and so the even pattern of glucuronic acid on the xylan is lost.

150 residues in the capsule are derived from UDP-glucuronic acid or its metabolites.

151 di- or trisaccharide and at position 6 with glucuronic acid or rhamnosyl glucuronic acid.

152 of acidic sugars N-acetylneuraminic acid and glucuronic acid out of lysosomes.

153 lation of the bacterial N-acetylglucosaminyl-glucuronic acid polymer K5 under conditions where the ho

154 effects in rodents, and are conjugated with glucuronic acid prior to excretion in human urine.

155 We propose that the regulation of UDP-glucuronic acid production in a specific subset of vulva

156 indicating that an alternate pathway for UDP-glucuronic acid production was not used.

157 d from partial desulfation demonstrated that glucuronic acid rather than iduronic acid residues are i

158 lysaccharide composed of N-acetylglucosamine-glucuronic acid repeats, is found in the extracellular m

159 acid and appears to require two 4-O-methyl-D-glucuronic acid residues for substrate recognition and/o

160 on, BtGH115A, hydrolyzes terminal 4-O-methyl-glucuronic acid residues from decorated arabinogalactan

161 dase was used to remove nonreducing-terminal glucuronic acid residues from oligosaccharides.

162 ily 2 glycosylhydrolases that cleaves beta-D-glucuronic acid residues from the nonreducing termini of

163 ly incorporated xylose (Xyl), arabinose, and glucuronic acid residues from their corresponding uridin

164 Odd-numbered oligosaccharides with terminal glucuronic acid residues isolated from hyaluronidase dig

165 ults in a specific defect in the addition of glucuronic acid residues onto xylans.

166 iency, both contain a trisaccharide with two glucuronic acid residues that enabled the identification

167 ride of alternating N-acetyl-glucosamine and glucuronic acid residues, is ubiquitously expressed in v

168 ride units of N-acetyl-D-galactosamine and d-glucuronic acid residues, modified with sulfated residue

169 idues but lacks any 2-O-sulfated iduronic or glucuronic acid residues.

170 rface than thought previously, such that a D-glucuronic acid ring makes stacking and ionic interactio

171 ynthesis mutants, such as the replacement of glucuronic acid side chains with methylglucuronic acid s

172 (GXMT) that catalyzes 4-O-methylation of the glucuronic acid substituents of this polysaccharide.

173 GUX1 (glucuronic acid substitution of xylan 1) and GUX2, recen

174 noglycan composed of N-acetylglucosamine and glucuronic acid subunits.

175 ernating beta1,3-N-acetylglucosamine-beta1,4-glucuronic acid sugar chain by the sequential addition o

176 nd xenobiotic compounds by linking them to a glucuronic acid sugar for GI excretion.

177 UGTs catalyze the covalent addition of glucuronic acid sugar moieties to a host of therapeutics

178 ects observed for amino acids closest to the glucuronic acid sugar transferred to the acceptor molecu

179 (Ssp) show homology to genes involved in UDP-glucuronic acid synthesis.

180 ls by linking glucuronic acid donated by UDP-glucuronic acid to a lipophilic acceptor substrate.

181 "reversible" catalytic mode by converting a glucuronic acid to an iduronic acid residue, and vice ve

182 lso serve as a one-way catalyst to convert a glucuronic acid to an iduronic acid residue, displaying

183 coded by PsUGT1 catalyzes conjugation of UDP-glucuronic acid to an unknown compound.

184 Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, i

185 precedented oxidative decarboxylation of UDP-glucuronic acid to form uridine 5'-(beta-l-threo-pentapy

186 )-dependent oxidative decarboxylation of UDP-glucuronic acid to generate a UDP-4'-keto-pentose sugar

187 ehydrogenase, which is capable of converting glucuronic acid to glucaric acid.

188 ylgalactosamine may precede epimerization of glucuronic acid to iduronic acid during dermatan sulfate

189 san with C(5)-epimerase converts some of the glucuronic acid to iduronic acid, thus becoming a substr

190 The HS C(5)-epimerase converts glucuronic acid to iduronic acid.

191 fication reactions is the epimerization of D-glucuronic acid to its C5-epimer L-iduronic acid, which

192 UGT1As add glucuronic acid to many drugs, modifying their activity

193 UGT1As add glucuronic acid to many drugs.

194 3)-glucuronyltransferases, one of which adds glucuronic acid to protein-linked galactose-beta(1, 4)-N

195 the NAD(+)-dependent decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and (ii) the N-1

196 One activity is to decarboxylate UDP-glucuronic acid to UDP-beta-l-threo-pentopyranosyl-4''-u

197 hase (AXS) catalyzes the conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose.

198 neoformans gene catalyzed conversion of UDP-glucuronic acid to UDP-xylose, as confirmed by NMR analy

199 ronic acid decarboxylase, which converts UDP-glucuronic acid to UDP-xylose.

200 ase (UXS) catalyzes decarboxylation of UDP-D-glucuronic acid to UDP-xylose.

201 +-dependent oxidative decarboxylation of UDP-glucuronic acid to yield the UDP-4''-ketopentose, uridin

202 olase-like catalytic mechanism to facilitate glucuronic acid transfer.

203 into two single-action glycosyltransferases (glucuronic acid transferase and N-acetylglucosamine tran

204 The abundance of the 4-O-methyl-alpha-d-glucuronic acid was not previously reported.

205 ercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were effective at physiological concentr

206 synthase for UDP-N-acetylglucosamine and UDP-glucuronic acid were estimated to be approximately 75 an

207 metabolites (methylated and conjugated with glucuronic acid) across hCMEC/D3 cells (a blood-brain ba

208 M) enhanced the potency of UDPG (but not UDP-glucuronic acid) by 7-fold.

209 Addition of the terminal residue (glucuronic acid) could not be detected; however, activit

210 tive cleavage of myo-inositol (MI) to give d-glucuronic acid, a committed step in MI catabolism.

211 s for the sugar donors UDP-galactose and UDP-glucuronic acid, although UDP-glucose was always preferr

212 des UDP-glucose dehydrogenase which produces glucuronic acid, an essential component for the synthesi

213 ssive oxidations of UDP-glucose to yield UDP-glucuronic acid, an essential precursor for matrix polys

214 DP-glucose dehydrogenase (Ugd) generates UDP-glucuronic acid, an important precursor for the producti

215 Chondroitin sulfate type C (CSC) contains glucuronic acid, and 90% of the GalNAc residues are sulf

216 Chondroitin sulfate type A (CSA) contains glucuronic acid, and 90% of the GalNAc residues are sulf

217 xylosyl residues is decorated by occasional glucuronic acid, and approximately one-half of the xylos

218 dic, alpha-fucosidic, alpha-mannosidic, beta-glucuronic acid, and beta-glucosamine linkages upon acti

219 ow that hemicellulose branches of arabinose, glucuronic acid, and especially glucuronate strengthen t

220 al other monosaccharides, including glucose, glucuronic acid, and N-acetylmannosamine, do not express

221 gy, we used purified S. equisimilis HAS, UDP-glucuronic acid, and UDP[beta-32P]-Glc-NAc to radiolabel

222 The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucos

223 e content of UDP-N-acetylhexosamines and UDP-glucuronic acid, correlating with the expression level o

224 4" oxidation and C-6" decarboxylation of UDP-glucuronic acid, followed by the C-4" transamination of

225 and C-6" decarboxylation of [alpha-(32)P]UDP-glucuronic acid, followed by transamination to generate

226 fucose, d-mannose, d-galactose, d-glucose, d-glucuronic acid, N-acetyl-d-galactosamine, and N-acetyl-

227 ccus neoformans comprises manose, xylose and glucuronic acid, of which mannose is the major constitue

228 ansport rate for N-acetylneuraminic acid and glucuronic acid, suggesting that it may be directly invo

229 specificity and allows phosphorylation of d-glucuronic acid, the 4-epimer of GalA.

230 charides containing terminal 4,5-unsaturated glucuronic acid, the nonreducing end disaccharide moiety

231 found in natural polysaccharides containing glucuronic acid, the oxidation of the primary alcohol at

232 cerevisiae expressing SQV-7 transported UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-gala

233 use steroid hormones are often conjugated to glucuronic acid, we hypothesized that Chst10 sulfates gl

234 talyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis

235 gh content of the nonsulfated disaccharide D-glucuronic acid-acetylated glucosamine (GlcA-GlcNAc).

236 nd glycolipid, termed Gl-X (mannose-alpha1-4-glucuronic acid-alpha1-diacylglycerol), which function a

237 a variety of monodisperse hyaluronan (beta 4-glucuronic acid-beta 3-N-acetylglucosamine (HA)) oligosa

238 duced repeating units of [-3-xylose-alpha1,3-glucuronic acid-beta1-].

239 uctions in the amount of [-3-xylose-alpha1,3-glucuronic acid-beta1-]n (hereafter referred to as LARGE

240 accharide repeating unit [-3-xylose-alpha1,3-glucuronic acid-beta1-]n by like-acetylglucosaminyltrans

241 Only glucuronic acid-containing ligands produced complexes, a

242 enosine diphosphate-activated platelets, UDP-glucuronic acid-dependent bilirubin conjugation was dete

243 al preparations resulted in no metabolite or glucuronic acid-HPPH conjugate production.

244 xylan, generating products with a 4-O-methyl-glucuronic acid-substituted xylose residue one position

245 UDP-glycosyltransferase UGT co-substrate UDP-glucuronic acid.

246 sulfate to the iduronic acid but not to the glucuronic acid.

247 fated heparosan, a polysaccharide containing glucuronic acid.

248 DP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.

249 ansformed cells on minimal medium containing glucuronic acid.

250 h as hormones by reversible conjugation with glucuronic acid.

251 daily diet and environment by conjugation to glucuronic acid.

252 s two oxidations of UDP-glucose to yield UDP-glucuronic acid.

253 position 6 with glucuronic acid or rhamnosyl glucuronic acid.

254 d environmental chemicals via conjugation to glucuronic acid.

255 mediate that is synthesized by ArnA from UDP-glucuronic acid.

256 neurotoxic bilirubin by conjugating it with glucuronic acid.

257 a pathway for l-Ara4N biosynthesis from UDP-glucuronic acid.

258 e polysaccharide contained galactosamine and glucuronic acid.

259 the related IAG sequence, where G is alpha-D-glucuronic acid.

260 inked mannan substituted with D-xylose and D-glucuronic acid.

261 e HA or any other molecules known to contain glucuronic acid.

262 e hydroxyl groups in glycosidic linkage with glucuronic acid.

263 ha-D-glucose, beta-D-glucose, rhamnose and D-glucuronic acid.

264 lycyrrhizin (GL) by hydrolysing one terminal glucuronic acid.

265 polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

266 cid, rhamnose, mannose, xylose and traces of glucuronic acid.

267 xtracts of the mutants completely lacked UDP-glucuronic acid:Galbeta1,3Gal-R glucuronosyltransferase

268 nts may be linked to the availability of UDP-glucuronic acid; therefore UGDH is an intriguing therape

269 ctive UDP-sugars to the non-reducing end of [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

270 with UDP and the acceptor substrate analog [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

271 n those measured on a mixture of pyruvic and glucuronic acids (logK = 2.2), which are the two constit

272 ccharide that is decorated with alpha-linked glucuronic and/or methylglucuronic acid (GlcA/MeGlcA).

273 residue arabinogalactan subunit with paired glucuronic carboxyls.

274 Glucuronic (GlcA) and iduronic acids (IdoA) were subsequ

275 Heparan sulfate consists of glucosamine and glucuronic/iduronic acid repeating disaccharides with va

276 ly bind anionic residues (sulfated rhamnose, glucuronic/iduronic acid).

277 fers the sulfo group to the 2-OH-position of glucuronic or iduronic acid.

278 e conformation of C-5 of the hexuronic acid (glucuronic versus iduronic) is not crucial, and (c) addi