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1 cherichia coli gene encoding the enzyme beta-glucuronidase).
2 modified enzyme was superior to native beta-glucuronidase.
3 and could label bystander proteins near beta-glucuronidase.
4 F-alpha-responsive, heparan sulfate-specific glucuronidase.
5 to its unconjugated counterpart by sulfatase/glucuronidase.
6 atal injection of an AAV vector expressing b-glucuronidase.
7 ivated by the oncologically significant beta-glucuronidase.
8 hol drug surrogates under the action of beta-glucuronidase.
9 he lysosomal hydrolases cathepsin D and beta-glucuronidase.
10 uidA, an E. coli-specific gene encoding beta-glucuronidase.
11 was based on a loop unique to bacterial beta-glucuronidases.
12 resent in microbial, but not mammalian, beta-glucuronidases.
14 n by strain B301D and reduced levels of beta-glucuronidase activities of the sypA::uidA and syrB1::ui
16 us and BG, have been reported to encode beta-glucuronidase activity among human colonic bacteria.
17 ssed in guard cells as shown by promoterbeta-glucuronidase activity and by whole-genome microarray.
18 vated FITC-TrapG did not interfere with beta-glucuronidase activity and could label bystander protein
19 ue-specific expression when analyzed by beta-glucuronidase activity assays, differences in gusA mRNA
20 on-sorbitol fermenting and negative for beta-glucuronidase activity but serotyped O nontypeable:H25 (
21 the BOS1-beta-glucuronidase transgene, beta-glucuronidase activity could be detected only after inhi
24 t the upstream sequence of POTH1 drives beta-glucuronidase activity in response to light and in assoc
29 ersions of the AtSUS2:promoter fused to Beta-glucuronidase activity revealed an internal 421 bp regio
30 ed only the BG gene gave relatively low beta-glucuronidase activity that was not induced by 4-nitroph
32 of near-IR (NIR) probes for imaging of beta-glucuronidase activity would be ideal to allow estimatio
33 on of root elongation, promotion of DR5-beta-glucuronidase activity, and reduction of Aux/IAA protein
34 two fluorescent probes for detection of beta-glucuronidase activity, one for the NIR range (containin
38 t be associated with elevated levels of beta-glucuronidase, an enzyme previously associated with blad
39 expression using northern and promoter-beta-glucuronidase analyses and found overlapping but distinc
40 ome analysis are supported by promoter::beta-glucuronidase analyses of CHX genes and by other methods
44 he influence of carbohydrate quality on beta-glucuronidase and cancer activity, deserve further scrut
45 ns were enzymatically deconjugated with beta-glucuronidase and extracted by a solid-phase extraction
46 pression pattern of recombinant ProBTS::beta-GLUCURONIDASE and found that it is expressed in developi
47 by expressing in soybean roots promoter beta-glucuronidase and green fluorescent protein fusions.
48 moter, when fused to the reporter genes beta-glucuronidase and green fluorescent protein, directed bi
49 udy sheds new light on the mechanism of beta-glucuronidase and helps to make industrial production of
50 hibition can be mimicked by recombinant beta-glucuronidase and is associated with proteolytic degrada
51 In addition, the use of mixtures of beta-glucuronidase and sulfatase enzymes from different sourc
52 promoter and protein fusions using the beta-glucuronidase and the green fluorescent protein, respect
55 e without inhibiting purified mammalian beta-glucuronidase, and they do not impact the survival of ei
56 us, by probing the actions of microbial beta-glucuronidases, and by understanding which substrate glu
57 additionally hydrolysed enzymatically (beta-glucuronidase/arylsulphatase, cellulase), the compounds
58 tant (fls2) as the scion and ALMT1(pro):beta-glucuronidase as the rootstock revealed that both COR an
59 the help of a single accessory enzyme (alpha-glucuronidase) as revealed by the sugar release assay.
60 b in roots were revealed by a promoter::beta-glucuronidase assay, with atU2AF35b expressed strongly i
62 tive real time-PCR, GGPPS promoter-GUS (beta-glucuronidase) assays and publicly available microarray
63 ytic kinetics catalyzed by bovine liver beta-glucuronidase at interstitial pH = 7.4 fit the Michaelis
64 ng a whole-gene translational fusion to beta-glucuronidase, AtSUC9 expression was found in sink tissu
68 that there is an increase in release of beta-glucuronidase by activated microglia into the extracellu
69 more, selective disruption of bacterial beta-glucuronidases by small molecule inhibitors alleviates t
70 hanol while incubating our samples with beta-glucuronidase, confirming that the methyl protons of EtG
71 , expression analysis of a PLP promoter-beta-glucuronidase construct in transgenic plants and in situ
72 ess ABA induction of the HVA22 promoter-beta-glucuronidase construct, while OsWRKY72 and -77 synergis
74 aphy (HPLC) showed that the activity of beta-glucuronidase could be increased by 2.66-fold via the ad
77 cture of one inhibitor bound to E. coli beta-glucuronidase demonstrates that it contacts and orders o
78 ation study, coadministration with oral beta-glucuronidase derived from Escherichia coli and pretreat
79 n of auxin redistribution using the DR5:beta-glucuronidase (DR5:GUS) auxin-responsive reporter showed
83 sidase enzyme (beta-gly) and W492G in a beta-glucuronidase enzyme (beta-gluc), in which we engineer i
84 In the GI tract, the microbiota express beta-glucuronidase enzymes that remove the glucuronic acid as
85 ve been conventionally studied by using beta-glucuronidase enzymes to release the phase I metabolites
87 apped on purified beta-glucuronidase or beta-glucuronidase-expressing CT26 cells (CT26/mbetaG) but no
88 but not on bovine serum albumin or non-beta-glucuronidase-expressing CT26 cells used as controls.
90 erse transcription PCR, promoter-driven beta-glucuronidase expression in transgenic plants, and Affym
94 a delay in the asymmetric auxin-induced beta-glucuronidase expression with gravistimulation as compar
95 of hydrogen peroxide-responsive AoPR10-beta-glucuronidase expression, suppression of plant stress/de
96 terologous in vivo Pv-ALF/phas-GUS (for beta-glucuronidase) expression system in transgenic Arabidops
97 iferase, green fluorescent protein, and beta-glucuronidase) facilitated in vivo profiling at the whol
99 rations from different sources, such as beta-glucuronidase from Escherichia coli, were found to conta
102 under different light treatments using beta-glucuronidase fusion constructs with the promoters of bo
105 rabidopsis plants containing the AtHD2C:beta-glucuronidase fusion gene revealed that AtHD2C was const
106 Arabidopsis plants containing the HDA19:beta-glucuronidase fusion gene revealed that HDA19 was expres
107 F-Y complexes, we have created promoter:beta-glucuronidase fusion lines for all 36 Arabidopsis genes.
108 -type and ABA response mutants, an ABI8-beta-glucuronidase fusion protein is localized primarily to t
109 y a promoter::green fluorescent protein-beta-glucuronidase fusion revealed strong gene expression in
110 at similar levels, and the two promoter-beta-glucuronidase fusion transgenes show very similar expres
114 P (green fluorescent protein) and NaKR1-beta-glucuronidase fusions driven by the native promoter.
115 , transgenic plants expressing ProRPL10:beta-glucuronidase fusions show that, while AtRPL10A and AtRP
116 dopsis lines carrying AtWRKY30 promoter-beta-glucuronidase fusions showed transcriptional activity in
117 lting in increased activity of secreted beta-glucuronidase fusions that result from gene trap integra
118 independently validated using promoter:beta-glucuronidase fusions with the MtCRE1 CK receptor gene a
119 idate genes was performed using promoterbeta-glucuronidase fusions, and all of these showed embryo sa
120 on of each GGT in plants containing GGT:beta-glucuronidase fusions, the temporal and spatial pattern
124 cteriaceae) and approximately 9% higher beta-glucuronidase gene abundance compared with nonresponders
125 ression of two reporter constructs: the beta-glucuronidase gene driven by the GA-inducible Amy32b alp
128 ed for the transgenic expression of the beta-glucuronidase gene fused to a synthetic auxin-inducible
129 nthase-like1 (MtCBS1), using a promoter-beta-glucuronidase gene fusion, which revealed expression in
130 nes in Arabidopsis thaliana by promoter-beta-glucuronidase gene fusions and by quantitative RT-PCR an
131 fusion of the GhCTL2 promoter to the beta -d-glucuronidase gene showed preferential reporter gene act
134 alyses using a complete set of promoter-beta-glucuronidase/green fluorescent protein reporter lines f
136 expression patterns as shown by DAO1pro:beta-glucuronidase (GUS) activity and DAO1pro:YFP-DAO1 signal
137 of VHA-c1, monitored by promoter-driven beta-glucuronidase (GUS) activity was responsive to light or
138 e and protein levels was analyzed using beta-glucuronidase (GUS) activity, quantitative reverse trans
139 s lines were constructed expressing the beta-glucuronidase (GUS) and green fluorescence protein (GFP)
140 PCR and transcriptional fusions to both beta-glucuronidase (GUS) and green fluorescent protein (GFP).
144 ently reported that PerT-GUS, a form of beta-glucuronidase (GUS) chemically modified to eliminate its
148 proof-of-principle experiments, a 35S::beta-glucuronidase (GUS) expression cassette was introduced i
150 dentified multiple lines that exhibited beta-glucuronidase (GUS) expression in the micropylar end of
157 nsgene with three direct repeats of the beta-glucuronidase (GUS) open reading frame (ORF) is associat
158 promoter and a coding region for either beta-glucuronidase (Gus) or glyphosate acetyltransferase (Gat
159 d region (UTR) was used to drive either beta-glucuronidase (GUS) or green fluorescent protein (GFP) e
160 1av1 promoter sequence was fused to the beta-glucuronidase (GUS) reporter gene and two varieties of A
161 system, we analyzed the activation of a beta-glucuronidase (GUS) reporter gene by enhancers contained
162 m tumefaciens strain AGL1 harboring the beta-glucuronidase (GUS) reporter gene driven by the cauliflo
164 med with the RTE1 promoter fused to the beta-glucuronidase (GUS) reporter gene revealed that RTE1 exp
165 and enhancer trap vectors carrying the beta-glucuronidase (GUS) reporter gene were inserted into the
166 gulator (ARR)5 gene promoter fused to a beta-glucuronidase (GUS) reporter gene, and cytokinin oxidase
167 NAC promoter elements were fused to the beta-glucuronidase (GUS) reporter gene, and spatial and tempo
168 5830 promoter activity, measured with a beta-glucuronidase (GUS) reporter gene, was primarily found i
170 taining an INPACT cassette encoding the beta-glucuronidase (GUS) reporter had negligible background e
171 ltransferase (UGT) operates in opposition to glucuronidase (GUS) to control activity of diverse metab
172 onsive Em promoter from wheat linked to beta-glucuronidase (GUS) to determine whether ABI3/VP1, trans
173 nic Arabidopsis lines bearing promoter::Beta-glucuronidase (GUS) transcriptional fusions as well as s
176 examined the differential expression of beta-glucuronidase (GUS) transgenes under the control of the
177 ransgenic plants harboring an SOB5:SOB5-beta-glucuronidase (GUS) translational fusion under the contr
178 irect the evolution of Escherichia coli beta-glucuronidase (GUS) variants with increased beta-galacto
179 pression of the reporter construct EBS: beta-glucuronidase (GUS) was detected in Arabidopsis root tip
180 d the minor activity, and ARGAH1-driven beta-glucuronidase (GUS) was expressed throughout the seedlin
182 te the fact that the uidA gene product, beta-glucuronidase (GUS), was produced only when the cells we
186 infection with Agrobacterium carrying a beta-glucuronidase (GUS, uidA) gene with an artificial intron
187 o regulate expression of uidA (encoding beta-glucuronidase; GUS) and the cytokinin-biosnythetic gene
188 mal storage disease caused by deficient beta-glucuronidase (GUSB) activity resulting in defective cat
189 cer and Transferrin receptor (TFRC) and beta-Glucuronidase (GUSB) in pancreatic cancer were identifie
191 ion of severe cardiac manifestations in beta-glucuronidase (GUSB) null mice BM-transplanted i.v. as n
192 ach, we identified the lysosomal enzyme beta-glucuronidase (GUSB), a member of a large family of core
193 ability to ferment sorbitol and express beta-glucuronidase have complicated its detection and identif
194 cells express low levels of the endo-beta-D-glucuronidase heparanase that increase upon NK cell acti
195 d the distribution of recombinant human beta-glucuronidase (hGUS) and reduction in storage by weekly
196 were unchanged compared to control (DR5:beta-glucuronidase), however, in the seedlings expressing the
198 n resistance, ectopically expressed DR5:beta-glucuronidase in developing embryos, and defective respo
200 -C1 induces chemotaxis and secretion of beta-glucuronidase in peripheral blood neutrophils with a pot
201 cted, incubation of these prodrugs with beta-glucuronidase in the culture medium led to much more eff
203 and Thi1.2 [thionin]) or SA (PR1 [PR1a-beta-glucuronidase in tobacco]) signaling when both signals w
204 express the reporter gusA gene encoding beta-glucuronidase in transgenic tobacco seeds relative to th
205 nhibitors that inhibit Escherichia coli beta-glucuronidase in vitro with Ki values between 180 nM and
206 ties from drug metabolites by bacterial beta-glucuronidases in the GI lumen can significantly damage
207 structural basis of selective microbial beta-glucuronidase inhibition, which may improve human drug e
208 ect of Klotho on NaPi-2a was blocked by beta-glucuronidase inhibitor but not by protease inhibitor.
209 Here we characterize novel microbial beta-glucuronidase inhibitors that inhibit Escherichia coli b
211 protein fusion, beta-galactosidase, and beta-glucuronidase) into the F14.5L, J2R (encoding thymidine
212 g of the abscission marker, Pro(PGAZAT):beta-glucuronidase, into the mutant reveals that while floral
217 sion of the auxin-induced reporter (DR5-beta-glucuronidase) is reduced in initiating lateral roots an
218 n patterns inferred from these promoter:beta-glucuronidase lines for roots, light- versus dark-grown
220 r-adapted vectors with three reporters, beta-glucuronidase, luciferase, and green fluorescent protein
221 the untranslated regions of StBEL5 to a beta-glucuronidase marker, translation in tobacco (Nicotiana
224 t are non-sorbitol fermenting (NSF) and beta-glucuronidase negative (GUD(-)) carry a large virulence
225 ent common ancestor of the contemporary beta-glucuronidase-negative, non-sorbitolfermenting STEC O157
226 apG was selectively trapped on purified beta-glucuronidase or beta-glucuronidase-expressing CT26 cell
227 herapy of necrotic tumors that liberate beta-glucuronidase or for antibody-directed enzyme prodrug th
229 mporal characterization, using Pro(HWS):beta-glucuronidase or Pro(HWS):green fluorescent protein fusi
230 ting stable transgenic lines expressing beta-glucuronidase plus (GUSplus), green fluorescent protein
231 55:H7 (sorbitol fermenting [SOR(+)] and beta-glucuronidase positive [GUD(+)]), through sequential gai
233 It is well-known that hydrolysis with beta-glucuronidase presents some limitations that may result
235 brain microvasculature, indicating that beta-glucuronidase reached brain parenchyma via the perivascu
237 tracer (18)F-FEAnGA was able to detect beta-glucuronidase release during neuroinflammation in a rat
239 studies with an ABA-INSENSITIVE2 (ABI4)-beta-glucuronidase reporter construct revealed that in root,
244 on analyses and promoter fusions to the beta-glucuronidase reporter gene confirmed the expression of
245 genes were variably induced in planta; beta-glucuronidase reporter gene expression analysis of a sub
246 ression pattern, determined by promoter-beta-glucuronidase reporter gene expression, is associated wi
247 irmed in transgenic plants expressing the ss-glucuronidase reporter gene fused to the NtPDR1 promoter
249 alyses of the WAKL4 promoter fused with the -glucuronidase reporter gene have shown that WAKL4 expres
250 ion start site direct expression of the beta-glucuronidase reporter gene primarily in the vascular ti
251 ression of the RPT2 promoter fused to a beta-glucuronidase reporter gene shows differential expressio
253 expression of the auxin-responsive DR5:beta-glucuronidase reporter gene, suggesting a perturbation i
254 four copies of the GCC-box fused to the beta-glucuronidase reporter gene, we showed that the GCC-box
255 ed in C. reinhardtii chloroplasts using beta-glucuronidase reporter genes, and the nearly identical C
256 oriented green fluorescent protein and beta-glucuronidase reporter genes, both transcripts and prote
257 ZATION SIGNAL-GREEN FLUORESCENT PROTEIN/beta-GLUCURONIDASE reporter lines throughout the life cycle,
260 auxin influx facilitator expression in beta-glucuronidase reporter plants revealed that AUXIN RESIST
261 dition, primer extension analyses and a beta-glucuronidase reporter system were used to quantitate tr
264 len, as indicated from a promoter::GUS (beta-glucuronidase) reporter analysis and expression profilin
265 OsGZF1 can down-regulate a GluB-1-GUS (beta-glucuronidase) reporter and OsGZF1 was also able to sign
267 OTH1 when fused to an expression marker beta-glucuronidase, repressed its translation in tobacco prot
268 and biological evaluation of the first beta-glucuronidase-responsive albumin-binding prodrug designe
269 ief incubation of the plasma with sulfatases/glucuronidases results in complete deconjugation of conj
270 2.66-fold via the addition of ISL to a beta-glucuronidase solution that contained GL at a 3:10 molar
273 -polymerase chain reaction and promoter:beta-glucuronidase studies indicate that all AtGT genes are t
275 The delivery of heparanase, the endo-beta-D-glucuronidase that degrades HS, accelerated the acquisit
277 ion of main chain xylanases as well as alpha-glucuronidases that release the alpha- (1-->2)-linked (M
278 ization of the provascular marker Athb8:beta-glucuronidase, the auxin-sensitive reporter DR5:beta-glu
280 n transgenic plants expressing the BOS1-beta-glucuronidase transgene, beta-glucuronidase activity cou
283 e-specific accumulation of an OBP3:OBP3-beta-glucuronidase translational fusion is regulated by light
286 etions, were fused to the reporter gene beta-glucuronidase (uidA) and analyzed in transgenic Nicotian
287 erpes simplex virus type 2 (HSV-2) UL24 beta-glucuronidase (UL24-betagluc) insertion mutant was deriv
288 ivo functional assay using the reporter beta-glucuronidase under the auxin-inducible DR5 promoter con
289 which can be rescued by expressing SUF4-beta-glucuronidase under the control of the SUF4 promoter.
290 otoplasts inhibited nuclear import of a beta-glucuronidase-VirD2 nuclear localization signal fusion p
291 ction affinity for the lysosomal enzyme beta-glucuronidase was also much lower (K(d) = 54 microm) as
293 IGF-II fused to the C terminus of human beta-glucuronidase was taken up by MPS VII fibroblasts in a m
298 and gusA3, were recovered that produced beta-glucuronidase with increased activity in neutral pH rang
299 All compounds are selective for E. coli beta-glucuronidase without inhibiting purified mammalian beta
300 r proteins, and the enzymes AguA (GH67 alpha-glucuronidase), XynA2 (GH10 endoxylanase), and XynB (GH4
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