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1 After oral administration, ezetimibe is glucuronidated.
2 or-alpha-muricholic acid); the remainder was glucuronidated.
5 nduction of UGT1A7 may explain the increased glucuronidating activities toward benzo(a)pyrene-7,8-dio
6 le in this interindividual variability, NNAL-glucuronidating activities were analyzed in 78 human liv
8 r L175Q, expressed in COS-1 cells, bilirubin glucuronidating activity at both pH 6.4 and 7.6 demonstr
11 Gunn rats and CN-I patients lacked SN-38 glucuronidating activity, indicating the role of UGT1 is
13 no- and dihydroxy-metabolites, together with glucuronidated and sulfated metabolites, were detected.
14 ve directly measured free, conjugated (e.g., glucuronidated), and substituted (e.g., chlorinated) for
16 ospho glucuronosyltransferase 2B17 (UGT2B17) glucuronidates androgens and xenobiotics including certa
17 determined that human recombinant UGT2B7 can glucuronidate atRA, 4-OH-RA, and 4-OH-RAc with activitie
18 xpressed by a baculovirus system selectively glucuronidated bile acids, particularly hyodeoxycholic a
19 a Tyr/Leu at position 170/171; this isoform glucuronidated bilirubin at 1/10 the level of that by UG
22 oisomers of one of its main metabolites, the glucuronidated carboxylate derivative, can be resolved b
25 cts that consumed JWH-018 primarily excreted glucuronidated conjugates of 5-(3-(1-naphthoyl)-1H-indol
26 tion of buprenorphine, norbuprenorphine, and glucuronidated conjugates was developed and validated.
28 d an HPLC peak corresponding to sulfated and glucuronidated estradiol in serum from wild-type but not
29 rometry revealed that Chst10 indeed sulfates glucuronidated estrogen, testosterone, and other steroid
33 stine and then in the liver to sulphated and glucuronidated forms that are exported to target organs.
38 lected, and the concentrations of FL and its glucuronidated metabolite (FL-Glu) were measured by HPLC
41 UGTs from the 1A family for their ability to glucuronidate p-nitrophenol (pNP) and 4-methylumbellifer
42 d, sulfated/hydroxylated, sulfated PCMC, and glucuronidated PCMC) were identified using the in vitro
44 yl)-1-butanol (NNAL), which, in turn, can be glucuronidated, producing [4-methylnitrosamino)-1-(3-pyr
46 c acid, we hypothesized that Chst10 sulfates glucuronidated steroid hormone to regulate steroid hormo
47 in the synthesis, since attempts to directly glucuronidate the aglycon, aglycon derivatives, and othe
49 cubated with human liver slices, norUDCA was glucuronidated, whereas UDCA was conjugated with glycine
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