ライフサイエンスコーパス: glutathione disulfide

1 otal glutathione and increased percentage of glutathione disulfide.

2 lutathione, and dissociation the presence of glutathione disulfide.

3 d involves a redox buffer of glutathione and glutathione disulfide.

4 l thiols, including oxidizing glutathione to glutathione disulfide.

5 titation of NADP+ following the reduction of glutathione disulfides.

6 ol oxidant diamide showed elevated levels of glutathione disulfide and increased protein-S-glutathion

7 sine, m-tyrosine, nitrotyrosine, dityrosine, glutathione disulfide, and 8-hydroxydeoxyguanosine) as w

8 DTNB, glutathione disulfide, and cystine were only marginally

9 , cystathionine, cysteine, hydrogen sulfide, glutathione disulfide, and glutathione, differed between

10 omitant formation of glutathione persulfide, glutathione disulfide, and H2S.

11 amounts of selenodiglutathione (GSSeSG) and glutathione disulfide are formed from selenite and 4 GSH

12 2 Tyr residues (residues 106 and 114) at the glutathione disulfide-binding site.

13 athione reductase catalyzes the reduction of glutathione disulfide by NADPH.

14 from substrates observed in the presence of glutathione disulfide can be explained by competition fo

15 in carbonyl content, reduced glutathione, or glutathione disulfide content, although the total consum

16 luding the endogenous compounds glutathione, glutathione disulfide, cysteine, cystine, homocysteine,

17 A significant decline in GSH-glutathione disulfide, cysteine-cystine, and vitamin E s

18 le acid-independent bile flow by stimulating glutathione disulfide excretion, effects that are indepe

19 ron reduced enzyme (EH(2)) interchanges with glutathione disulfide forming two molecules of glutathio

20 The redox state of the glutathione disulfide-glutathione couple is a well known

21 idney, which was consistent with a decreased glutathione disulfide/glutathione ratio.

22 de phosphate , flavin adenine dinucleotide , glutathione disulfide/glutathione).

23 Plasma glutathione/glutathione disulfide (GSH/GSSG) and cysteine/cystine (C

24 We demonstrate that the glutathione/glutathione disulfide (GSH/GSSG) pair controls the coppe

25 corresponds to the intracellular glutathione/glutathione disulfide (GSH/GSSG) potential at the redox

26 levels of Cys, CySS, glutathione (GSH), and glutathione disulfide (GSSG) and calculated E(h) accordi

27 ociated with an increase of GSH oxidation to glutathione disulfide (GSSG) and decrease of the GSH/GSS

28 Under traditional conditions, 0.125 mM glutathione disulfide (GSSG) and no glutathione (GSH), t

29 have been identified as transporters of GSH, glutathione disulfide (GSSG) and/or GSH conjugates (GS-X

30 Reduced glutathione (GSH) and glutathione disulfide (GSSG) are critical modulators of

31 lated TK2 was detected after the addition of glutathione disulfide (GSSG) but not GSH.

32 Both proteins selectively transported glutathione disulfide (GSSG) but not reduced glutathione

33 the enzymatic mechanism of the reduction of glutathione disulfide (GSSG) by the reduced a domain of

34 The glutathione disulfide (GSSG) formed can be recycled to G

35 e of the importance of glutathione (GSH) and glutathione disulfide (GSSG) in cellular signal transduc

36 ne reductase (GR) catalyzes the reduction of glutathione disulfide (GSSG) into reduced glutathione (G

37 In healthy cells, glutathione disulfide (GSSG) is rapidly reduced back to

38 Cellular glutathione (GSH) and glutathione disulfide (GSSG) levels were measured by hig

39 Biological disulfides such as glutathione disulfide (GSSG) oxidize MT with concomitant

40 otential whereas a dramatic oxidation in GSH/glutathione disulfide (GSSG) pool occurred in parental r

41 educed glutathione (GSH) or a mixture of GSH/glutathione disulfide (GSSG) potentiated platelet aggreg

42 ficant decrease in reduced glutathione (GSH)/glutathione disulfide (GSSG) ratio.

43 oxidative damage markers, glutathione (GSH)/glutathione disulfide (GSSG) ratios, and activation of s

44 Glutathione disulfide (GSSG) reductase (GR) activity was

45 diamide and reduced glutathione or with only glutathione disulfide (GSSG) results in a modification d

46 This enzyme catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH

47 In contrast to GSH, glutathione disulfide (GSSG) was a potent stimulator of

48 Glutathione disulfide (GSSG) was not transported in eith

49 Cx50), whereas permeation of divalent anion glutathione disulfide (GSSG) was undetectable.

50 Intracellular glutathione (GSH) and glutathione disulfide (GSSG) were measured by HPLC.

51 ant increase of hepatic and plasma levels of glutathione disulfide (GSSG), an indicator of oxidant st

52 t MAO-generated H2O2 oxidizes glutathione to glutathione disulfide (GSSG), which undergoes thiol-disu

53 eloped for quantification of glutathione and glutathione disulfide (GSSG), which was used for the det

54 orption and orientation of the model peptide glutathione disulfide (GSSG).

55 n to reactive oxygen species, thus producing glutathione disulfide (GSSG).

56 hiols, including oxidation of glutathione to glutathione disulfide (GSSG).

57 uce molecular oxygen, forming superoxide and glutathione disulfide (GSSG).

58 se (NOX4) and early significant increases in glutathione disulfide (GSSG)/glutathione (GSH), a marker

59 lood glutathione (reduced glutathione [GSH], glutathione disulfide [GSSG], and total glutathione [tGS

60 in the presence of GSH reveals a molecule of glutathione disulfide in the active site.

61 GSH decreases, whereas glutathione disulfide increases, ATP binding.

62 e by glutathione and reoxidation of EH(2) by glutathione disulfide indicate that the mixed disulfide

63 of O2(.-) and H2O2, increases in glutathione/glutathione disulfide (indicative of oxidative stress),

64 Exposure to glutathione disulfide induced cMyBP-C S-glutathiolation,

65 e oxidants hydrogen peroxide, superoxide and glutathione disulfide inhibited the phosphatase activity

66 previously shown that glutathione (GSH) and glutathione disulfide interact with metallothionein (MT)

67 NOV-002 is a novel glutathione disulfide mimetic that when administered in

68 evels of total glutathione (glutathione plus glutathione disulfide), occurring before losses in mitoc

69 c transfer from enzymes to thionein, whereas glutathione disulfide oxidizes MT with enhanced release

70 Glutaredoxin 2 is the major glutathione disulfide oxidoreductase in E. coli, but its

71 ed for glutaredoxin 2, a vertebrate-specific glutathione-disulfide oxidoreductase with a critical rol

72 Increased intracellular reduced glutathione/glutathione disulfide ratio and greater nuclear redox fa

73 B26 cells exhibited an increased glutathione/glutathione disulfide ratio in the medium in comparison

74 smutase activity, the reduced glutathione-to-glutathione disulfide ratio, and lipid peroxidation indi

75 d glutathione to maintain a high glutathione/glutathione disulfide ratio.

76 cipitated by changing either the glutathione/glutathione-disulfide ratio (GSH/GSSG) and/or the reduce

77 Glutathione/glutathione disulfide ratios were decreased by adenoviru

78 ecrease in intracellular reduced glutathione:glutathione disulfide ratios, protecting cells from prot

79 le, the inhibitory potency of the kinase was glutathione disulfide S-dioxide (GS-DSDO) (IC50, approxi

80 utathione disulfide S-monoxide (GS-DSMO) and glutathione disulfide S-dioxide (GS-DSDO), we showed tha

81 id, glutathione disulfide S-oxide (GS(O)SG), glutathione disulfide S-dioxide, and GSSG as the major d

82 CPS-DSDO) (IC50, approximately 450 microM) > glutathione disulfide S-monoxide (GS-DSMO) and captopril

83 otential mediators of oxidants in the brain, glutathione disulfide S-monoxide (GS-DSMO) and glutathio

84 We identified glutathione sulfonic acid, glutathione disulfide S-oxide (GS(O)SG), glutathione dis

85 dation of CaMKII, probably via the action of glutathione disulfide S-oxides or their analogues, may b

86 g) altered in tissue and serum, and cysteine-glutathione disulfide showed the highest change (232.4-f

87 f glutathione, nitrosylated glutathione, and glutathione disulfide solubilized in 2 M HCl.

88 ione, and it is involved in the formation of glutathione disulfide, the oxidized form of glutathione.

89 e reductase (Gsr) catalyzes the reduction of glutathione disulfide to glutathione, which plays an imp

90 rogenase activity also have higher levels of glutathione disulfide under aerobic conditions, so it is

91 TR/GR-null livers cannot reduce oxidized glutathione disulfide using NADPH but still require cont

92 nsensive pathway is subject to inhibition by glutathione disulfide, vanadate, verapamil, and vinblast

93 .0001), which were almost entirely caused by glutathione disulfide, whereas the excretion of reduced

94 The pheromone nereithione (cysteine-glutathione disulfide), which is released by swimming fe

95 ne (GSH) was accompanied by the formation of glutathione disulfide, which could not be ascribed to th

96 SO significantly increased the percentage of glutathione disulfide, which was also inhibited by NAC.

97 The reaction of glutathione disulfide with EH(2) is stoichiometric in th

98 Oxidation of GSH to glutathione disulfide with H2O2 and glutathione peroxida

99 e catalyzes the NADPH-dependent reduction of glutathione disulfide, yielding two molecules of glutath