ライフサイエンスコーパス: glycerate

1 ry metabolites l-serine and 1,3-bisphospho-d-glycerate.

2 ereas PLGG1 alone accounts for the import of glycerate.

3 elevated urinary excretion of oxalate and L-glycerate.

4 ts for the substrates and the activator, 3-P-glycerate.

5 amic acid mutant enzyme was inhibited by 3-P-glycerate.

6 chemistry was assessed by using [14C-methyl]glycerate.

7 at position 382 influence the binding of 3-P-glycerate.

8 idues are not involved in the binding of 3-P-glycerate.

9 ant enzymes with apparent affinities for 3-P-glycerate 10-160-fold lower than that of the wild-type e

10 and in vivo application of sodium [1-(13)C]-glycerate ([(13)C]-Glyc) as a novel probe for evaluating

11 of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-e

12 Members of a novel glycerate-2-kinase (GK-II) family were tentatively ident

13 midodiphosphate (Mg-AMP-PNP) and 3-phospho-D-glycerate (3-PG) has been determined by X-ray crystallog

14 starting with methyl 2,3-O-isopropylidene-d-glycerate (4) and D-ribo-phytosphingosine (3), respectiv

15 haelis constants (K(m)) for both 3-phospho-D-glycerate and ATP are increased only by three or fourfol

16 bolism as well as mineral nutrition and that glycerate and glutamine are the main metabolites respond

17 catalyzes the interconversion of 2-phospho-D-glycerate and phosphoenolpyruvate.

18 atalyzed the NAD(+)-dependent oxidation of d-glycerate and the NADH-dependent reduction of tartronate

19 bolism, as well as decreases in pyruvate and glycerate as CodY activity decreased.

20 , producing an operon clearly designed for d-glycerate biosynthesis from tartronate semialdehyde.

21 exchange of the alpha-proton of 2-phospho-D-glycerate but not the complete dehydration, was assayed

22 atalyzed the NAD(+)-dependent oxidation of d-glycerate but was significantly more efficient in the ox

23 sphosphate carboxylase [Rubisco; 3-phospho-D-glycerate carboxy-lyase (dimerizing), EC 4.1.1.39].

24 The reduction of hydroxypyruvate to glycerate catalyzed by hydroxypyruvate reductase (HPR) i

25 ruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities.

26 achment, and intramolecular cyclization of a glycerate-derived three-carbon unit, which forms the cor

27 but forms pyruvate, rather than 3-phospho-D-glycerate, due to incapacity in protonation of the termi

28 rom inactivation most effectively, while 3-P-glycerate, fructose-1,6-P2, pyridoxal-P, and ATP plus ma

29 yed in the dehydration reaction (2-phospho-D-glycerate --> phosphoenolpyruvate + H(2)O) at different

30 (i.e. glycine not part of the production of glycerate in support of photosynthesis) is either fully

31 the progressive identification of acetyl-(R)-glycerate (k(cat)/K(m) = 4 x 10(2) M(-1) s(-1)), acetyl

32 allelic differences in 5 core genes encoding glycerate kinase (glxK), valine-pyruvate transaminase (a

33 gckA and ttuD might be structural genes for glycerate kinase and that the serine cycle and the tartr

34 gene (gckA) responsible for the activity of glycerate kinase has been identified within a chromosoma

35 Mn.ATP bound to the active site of yeast 3-P-glycerate kinase is presented.

36 dolase, tartronate semialdehyde reductase, a glycerate kinase that generates 2-phosphoglycerate as pr

37 The mutant accumulates glycolate and glycerate, leading to the hypothesis that PLGG1 is a gly

38 t reactions in the mitochondrion that supply glycerate may support TAG synthesis.

39 e is transferred from the enzyme back to the glycerate moiety.

40 o glycolate molecules with the import of one glycerate molecule during photorespiration.

41 The apparent affinity for 3-P-glycerate of this double-mutant enzyme was 104-fold lowe

42 ncoding the enzymes of the d-glucarate and d-glycerate pathways (gudT, gudD, garR, garL, garK) are si

43 hat catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to form phosphoenolpyruvate (PEP), is a

44 group of the substrate/product, 2-phospho-D-glycerate/phosphoenolpyruvate, and induces binding of th

45 phosphate, in the absence or presence of 3-P-glycerate, respectively.

46 osphate in the absence of the activator, 3-P-glycerate, than that of the wild-type enzyme.

47 sphorylase is involved in the binding of 3-P-glycerate, the allosteric activator.

48 alyzes the reduction of hydroxypyruvate to D-glycerate, the reduction of glyoxylate to glycolate and

49 then transformed through hydroxypyruvate and glycerate to enter central metabolism at phosphoglycerat

50 yoxylate to glycolate and the oxidation of D-glycerate to hydroxypyruvate.

51 to the O2 or O3 positions of the reoriented glycerate to yield the PGA product.

52 analyses, we identified Plastidal glycolate glycerate translocator 1 (PLGG1) as a candidate core pho

53 nockout line of both BASS6 and the glycolate/glycerate transporter PLGG1 (bass6, plgg1) showed an add

54 that PLGG1 is the chloroplastidic glycolate/glycerate transporter, which is required for the functio

55 to the hypothesis that PLGG1 is a glycolate/glycerate transporter.

56 ays that lead to GK-II-driven utilization of glycerate via a glycolysis/gluconeogenesis route.

57 M1401, respectively), that convert serine to glycerate via hydroxypyruvate.

58 he exchange of the C-2 proton of 2-phospho-D-glycerate with deuterium in D2O, whereas both the E211Q