ライフサイエンスコーパス: glycerol-3-phosphate acyltransferase

1 acid synthase, acetyl-CoA carboxylase 1, and glycerol-3-phosphate acyltransferase.

2 c enzymes, including fatty acid synthase and glycerol-3-phosphate acyltransferase.

3 l-3-phosphate dehydrogenase, and plsB, an sn-glycerol-3-phosphate acyltransferase.

4 in homology modeling of both the AGPATs with glycerol-3-phosphate acyltransferase 1 (GPAT1) revealed

5 s impair insulin signaling, we overexpressed glycerol-3-phosphate acyltransferase-1 (GPAT1) in primar

6 osis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which ca

7 vitro studies suggest that the mitochondrial glycerol-3-phosphate acyltransferase-1 (mtGPAT1) isoform

8 Overexpressing glycerol-3-phosphate acyltransferase-1 or -4 inhibited i

9 ulating oleoyl-CoA utilization by microsomal glycerol-3-phosphate acyltransferase 3.2-fold and protec

10 Glycerol-3-phosphate acyltransferase 4 (GPAT4), which ca

11 Glycerol-3-phosphate acyltransferase-4 (GPAT4) null pups

12 in the model plant Arabidopsis thaliana: the glycerol-3-phosphate acyltransferase 6 (GPAT6) and a mem

13 mutation in the soluble chloroplastic enzyme glycerol-3-phosphate acyltransferase (ACT1) completely r

14 loss of both dihydroxyacetone phosphate and glycerol-3-phosphate acyltransferase activities in yeast

15 AT resulted in a complete loss of Leishmania glycerol-3-phosphate acyltransferase activity and a majo

16 shmania major promastigotes express a single glycerol-3-phosphate acyltransferase activity important

17 However, glycerol-3-phosphate acyltransferase activity was not de

18 Furthermore, mitochondrial glycerol-3-phosphate acyltransferase activity was reduce

19 on of LPT1 had a minimal effect on 1-acyl-sn-glycerol-3-phosphate acyltransferase activity, but overe

20 iana GPAT5, encoding a protein with acyl-CoA:glycerol-3-phosphate acyltransferase activity.

21 nnotated as lysophosphatidic acid (1-acyl-sn-glycerol-3-phosphate) acyltransferase (AGPAT).

22 enzymes: glycerol 3-phosphate dehydrogenase, glycerol 3-phosphate acyltransferase and lysophosphatidi

23 alyses revealed that LmGAT is a low-affinity glycerol-3-phosphate acyltransferase and exhibits higher

24 act1, which encodes the chloroplast acyl-ACP:glycerol-3-phosphate acyltransferase, and one in lpat1,

25 ose-6-phosphate dehydrogenase, malic enzyme, glycerol-3-phosphate acyltransferase, and stearoyl-CoA d

26 oelii glycerol 3-phosphate dehydrogenase and glycerol 3-phosphate acyltransferase are expressed only

27 e homozygous mutant deficient of the plastid glycerol-3-phosphate acyltransferase; both mutations blo

28 mice; however, the activities of microsomal glycerol-3-phosphate acyltransferase, diacylglycerol acy

29 erichia coli, LPA acyltransferase (1-acyl-sn-glycerol-3-phosphate acyltransferase; EC 2.3.1.51) catal

30 In this study, we targeted the glycerol-3-phosphate acyltransferase GPAM along with cho

31 -relevant key nodes, including mitochondrial glycerol-3-phosphate acyltransferase (GPAM), were expose

32 Glycerol 3-phosphate acyltransferase (GPAT) catalyzes th

33 ansferases essential for cutin biosynthesis, glycerol-3-phosphate acyltransferase (GPAT) 4 and GPAT8.

34 Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) catalyzes th

35 Glycerol-3-phosphate acyltransferase (GPAT) catalyzes th

36 Glycerol-3-phosphate acyltransferase (GPAT) catalyzes th

37 t that LpxL shares distant homology with the glycerol-3-phosphate acyltransferase (GPAT) family, incl

38 Arabidopsis (Arabidopsis thaliana) has eight glycerol-3-phosphate acyltransferase (GPAT) genes that a

39 tion, enzymatic activity of liver microsomal glycerol-3-phosphate acyltransferase (GPAT) increased 4-

40 Four glycerol-3-phosphate acyltransferase (GPAT) isoforms, ea

41 The topography of mitochondrial glycerol-3-phosphate acyltransferase (GPAT) was determin

42 We demonstrate that the mRNA levels of glycerol-3-phosphate acyltransferase (GPAT), a mitochond

43 Gene expression of sn-glycerol-3-phosphate acyltransferase (GPAT), diacylglyce

44 sequences from various acyltransferases [sn-glycerol-3-phosphate acyltransferase (GPAT), lysophospha

45 In addition, the activity of sn-glycerol-3-phosphate acyltransferase (GPAT), which like

46 fatty acid synthase (FAS) and mitochondrial glycerol-3-phosphate acyltransferase (GPAT)-involved in

47 d storage triacylglycerols is catalyzed by a glycerol-3-phosphate acyltransferase (GPAT).

48 t study, we show that AGPAT6 is a microsomal glycerol-3-phosphate acyltransferase (GPAT).

49 Microsomal and mitochondrial isoforms of glycerol-3-phosphate acyltransferase (GPAT; E.C. 2.3.1.1

50 The expression of glycerol-3-phosphate acyltransferase (GPAT3) was examine

51 vo pathway for TAG synthesis is catalyzed by glycerol-3-phosphate acyltransferases (GPATs).

52 The glycerol-3-phosphate acyltransferase, mitochondrial hapl

53 nzymes involved in both TAG synthesis, Gpam (glycerol-3-phosphate acyltransferase, mitochondrial), Dg

54 Glycerol-3-phosphate acyltransferase mRNA fell by 57% an

55 ave previously shown rat liver mitochondrial glycerol-3-phosphate acyltransferase (mtGAT), which cata

56 Second-site mutations in the ACT1-encoded glycerol-3-phosphate acyltransferase or GLY1-encoded gly

57 epresentative members of this family, the sn-glycerol-3-phosphate acyltransferase (PlsB) and the bifu

58 The sn-glycerol-3-phosphate acyltransferase (plsB) catalyzes th

59 The sn-glycerol-3-phosphate acyltransferase (plsB) of Escherich

60 sD was most closely related to the 1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC) gene family

61 SF binds constitutively to the mitochondrial glycerol 3-phosphate acyltransferase promoter during fas

62 cooperative activation of the mitochondrial glycerol-3-phosphate acyltransferase promoter by USF and

63 xotrophs, and this lipid export requires the glycerol-3-phosphate acyltransferase RAM2, a direct targ

64 hesis is primarily mediated by the 1-acyl-sn-glycerol-3-phosphate acyltransferase reaction.

65 s based on competition between Ole1p and the glycerol-3-phosphate acyltransferase Sct1p/Gat2p for the

66 e PlsB26 protein had a significantly reduced glycerol-3-phosphate acyltransferase specific activity c