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1 and d-allo-Thr along with d-amino acids and glycine.
2 t and endogenous synthesis from arginine and glycine.
3 ggered in response to certain bile acids and glycine.
4 fications, including a rare thioamidation of glycine.
5 scriminate between D-amino acids and achiral glycine.
6 by VEGF led to an increase in intracellular glycine.
7 made from calcite single crystals containing glycine (0-7 mol%) or aspartic acid (0-4 mol%), we eluci
10 ist at GluN1/2A (100% response compared with glycine), a partial agonist at GluN1/2B and GluN1/2D (10
11 n of the upper side chain (proton donor) and glycine acetamide of the lower side chain (proton accept
12 , which demonstrated ex vivo potentiation of glycine-activated current in mouse dorsal horn neurons f
13 ptors (iGluRs) that are distantly related to glycine-activated NMDA receptors and that bind glycine w
15 sed a significant reduction in glutamate and glycine agonist potency, whilst D731N was non-responsive
16 at a single nitrogen atom substitution for a glycine alpha-carbon increases the peptide's triple heli
17 s of d-xylose, d-arabinose and d-ribose with glycine, alpha-l- or beta-alanine and l-valine in pH 7.0
18 Its biosynthesis is reasoned to proceed via glycine-, alpha-hydroxyglycine-, glycyllysine-, and glyc
22 svA is similar to that of the human arginine-glycine amidinotransferase in the creatine biosynthesis
23 ne, an N-methyl derivative of the amino acid glycine and a metabolic product of choline, plays an imp
24 at GluN2C-containing receptors compared with glycine and a partial agonist at GluN2B-containing recep
25 methyltransferse (SHMT) converts serine into glycine and a tetrahydrofolate-bound one-carbon unit.
27 sfAFP has low sequence complexity with 46% glycine and an interior filled only with backbone H-bond
30 ses of sarcosine and its natural precursors, glycine and choline, were performed from independent hum
31 hemistry and electrophysiology, we show that glycine and D-serine relative availability at rat hippoc
34 ggests that neurons in the VNLL release both glycine and GABA in the ICC, but functional evidence for
35 (1-deoxy-1-fructosylglycine) formation from glycine and glucose, varying temperature, water activity
37 selectivity and yield: 40% yield for lauroyl glycine and less than 5% for dipeptide after 96h of synt
40 not differ in their premature responding and glycine and serine levels in vmPFC during the performanc
41 ty is associated with reduced recruitment of glycine and serine neurotransmitters in the ventromedial
42 resent evidence that deficient activation of glycine and serine release in the ventral medial prefron
43 ed blunted task-related recruitment of vmPFC glycine and serine release, and the loss of an inverse r
44 ation of pentameric GlyR structures bound to glycine and strychnine have contributed to visualizing t
45 ylalanine, valine, GABA, glutamine, alanine, glycine and taurine were separated and detected at conce
49 ple helical collagen peptides containing aza-glycine and we demonstrate that minimal alteration to th
50 amylation, the posttranslational addition of glycines and glutamates to genetically encoded glutamate
51 uman serum albumin, neurotensin, creatinine, glycine, and alanine) were retained in the samples for s
52 list libraries biased with tyrosine, serine, glycine, and arginine to form binding surfaces for speci
53 significant stepwise increases of sarcosine, glycine, and choline tissue levels from benign prostate
54 three primary neurotransmitters (glutamate, glycine, and GABA) in the auditory brainstem of Fmr1 kno
55 -hydroxy-5-methyl-4-isoxazolepropionic acid, glycine, and gamma-aminobutyric acid-A receptors), were
57 ine-glycine (GSG) index (glutamate/[serine + glycine]) and tested for an association with liver histo
58 The non-essential amino acids serine and glycine are used in multiple anabolic processes that sup
62 plasticity and accessibility of the arginine-glycine-aspartic acid (RGD) binding site in FN, which, i
64 erally alphavbeta6, via a conserved arginine-glycine-aspartic acid (RGD) motif in the exposed, antige
65 mation beta5/beta3 integrins and an arginine-glycine-aspartic acid (RGD) sequence in the first extrac
67 d to mimic the tripeptide sequence (arginine-glycine-aspartic acid) of the natural ligands; however,
68 udy, we report the efficacy of RGD (arginine-glycine-aspartic acid) peptide-modified polylactic acid-
69 te bioinks containing cell adhesive Arginine-Glycine-Aspartic acid-Serene (RGDS) peptide and/or nanoc
73 essed in HEK cells, reduced the potencies of glycine, beta-alanine and taurine by 9-, 6- and 3-fold r
74 t, baseline levels of betaine, also known as glycine betaine (hazard ratio 0.84 per SD log metabolite
76 ing choline, acetylcholine, L-carnitine, and glycine betaine effectively.The choline-binding protein
77 in the oligopeptide importer (oppABCDF) and glycine betaine importer (gbuABC) allowed DeltadacA muta
79 (Kd ) in the nanomolar range for choline and glycine betaine, micromolar Kd for stachydrine and trigo
80 line, glycerophosphocholine, phosphocholine, glycine betaine, N-methylproline, proline betaine (stach
82 t oligopeptides act as osmolytes, similar to glycine betaine, to disrupt intracellular osmotic pressu
87 ne, a co-agonist of the NMDA receptor at the glycine-binding site, can be released by astrocytes in a
88 referential solvation arguments, betaine and glycine both increase the surface tension at the air-wat
90 an use cell wall precursors having different glycine branch lengths (penta-, tri-, or monoglycine), w
95 ncoding the LiaS protein with an arginine-to-glycine change at position 135 [liaS(R135G)]) recapitula
101 ignificant amount of respiration, use serine-glycine cycle and produce ethanol in mitochondria as opp
102 -4-mercapto-4-methylpentan-2-one-l-cysteinyl-glycine (CysGly-4MMP) and S-4-mercapto-4-methylpentan-2-
104 rent subunit composition after activation by glycine/D-serine or glutamate and hence presents the fir
107 methods, we identified this elusive phase as glycine dihydrate (GDH), representing the first report o
111 thranilate-derived amino ketones with an aza-glycine equivalent, chemoselective nitrogen functionaliz
114 water structure to the least extent, whereas glycine exerts the greatest influence on the water struc
115 ed polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport recepto
117 inds to polymeric forms of the phenylalanine:glycine (FG) repeat domain, which is shared by several p
118 ne-third of these Nups contain phenylalanine-glycine (FG)-rich repeats, forming a diffusion barrier,
119 ures of skepinone-L scaffold like inducing a glycine flip at the hinge region and occupying both hydr
120 y driven and can be reversed by substituting glycine for alanine in position 2, forming [YG(L)PAA+H](
121 s-specific glyS T-box controls the supply of glycine for both ribosomal translation and cell wall syn
123 enesis and providing better understanding of glycine function in angiogenesis, which may provide valu
124 Here, we show that a single Arginine (R) to Glycine (G) mutation at position 76 in the refp17 backbo
125 spartate (NMDA) receptors are glutamate- and glycine-gated channels that flux Na(+) and Ca(2+) into p
126 ceptor family, GluN1/GluN3 receptors produce glycine-gated deeply desensitising currents that are ins
128 Small proteins characterized by a double-glycine (GG) secretion motif, typical of secreted bacter
129 ted more slowly than predicted, and proline, glycine, glutamate, lysine and arginine, which were all
132 was to quantify in vivo glutamate (Glu) and glycine (Gly) levels in patients with first-episode psyc
133 RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 ch
134 ubiquitinated proteins with trypsin yields a glycine-glycine remnant bound to the modified lysine res
135 llected samples of whole blood from codon 96 glycine/glycine, captive white-tailed deer that were ana
137 ion x insulin), and the new glutamate-serine-glycine (GSG) index (glutamate/[serine + glycine]) and t
138 is, human myeloperoxidase was incubated with glycine, H2O2, malondialdehyde, and a lysine analog in P
139 installation of a (4-methylhexa-2,4-dienoyl)glycine handle across a hexadepsipeptide core contribute
142 hed-chain and aromatic amino acids (alanine, glycine, histidine, phenylalanine, leucine, isoleucine,
146 has important implications for the state of glycine in aqueous solution and the mechanisms of glycin
147 d that replacement of the strictly conserved glycine in collagen with aza-glycine provides a general
150 following dietary restriction of serine and glycine in these models was further improved by antagoni
153 d conformational constraints provided by aza-glycine increases the thermal stability and rate of fold
156 vior of the centrosymmetric crystal of alpha-glycine is resolved by the discovery of a polar, several
158 ine, l-glutamine, l-threonine, l-arginine, l-glycine, l-proline, l-serine, l-alanine, and l-glutamic
159 transgenic plants such as aspartate, lysine, glycine, leucine and threonine with no changes in the am
160 ced toxicity in Escherichia coli even at low-glycine levels which is alleviated by alanine supplement
161 (+)-67 significantly elevated extracellular glycine levels within the medial prefrontal cortex (mPFC
162 iated with altered cortical myo-inositol and glycine levels, suggesting sleep loss-induced modificati
164 n N-methyl-D-aspartate (NMDA) modulator with glycine-like partial agonist properties; like the NMDA r
166 itored the thermal formation of early ribose-glycine Maillard reaction products over time by ion cycl
168 es along with expression studies in soybean [Glycine max (L.) Merr.] were leveraged to dissect the ge
170 gene families with those of fellow legumes, Glycine max and Phaseolus vulgaris, in addition to the m
173 ic analysis between Arabidopsis thaliana and Glycine max root hair genes reveals the evolution of the
174 sulfonate mutagenized population of soybean (Glycine max) 'Forrest' was screened to identify mutants
175 hemical capacity was measured in 67 soybean (Glycine max) accessions showing large variation in leaf
176 gh-antioxidant black legumes, black soybean (Glycine max) and black turtle bean (Phaseolus vulgaris),
177 sis (Arabidopsis thaliana) CPK4 and soybean (Glycine max) CDPKbeta are RcCDPK1 orthologs that effecti
178 The overexpression of AraEXLB8 in soybean (Glycine max) composite plants remarkably decreased the n
179 nd among-cultivar components across soybean (Glycine max) grown under both controlled and field condi
188 ductance (gs )) for legumes Cicer arietinum, Glycine max, Lupinus alba and Vicia faba, nonlegume dico
191 e inhibitor, DMOG [N-(2-Methoxy-2-oxoacetyl) glycine methyl ester], that can partially inhibit mangan
192 Importantly, AIS cases harbor mainly non-glycine missense mutations and lack the clinical feature
196 Precursor processing after the first di-glycine motif by the ubiquitin-specific proteases Ubp5 a
199 most widely studied member is N-arachidonoyl glycine (NAGly), which differs structurally from the end
200 both antibodies share a canonical asparagine-glycine (NG) motif in a structural loop, this is prone t
202 inding affinity of Kapbeta1 to phenylalanine-glycine nucleoporins (FG Nups), which is comparable with
203 trimethylamine N-oxide (TMAO), betaine, and glycine, on the hydrophobic collapse of an elastin-like
204 ificant differences in blood serum levels of glycine (P = 4.04 x 10(-6)) and serine (P = 2.48 x 10(-4
207 ded mutation of a critical residue, F270, to glycine perturbs the Si site, allowing structural determ
208 vealing that in one case a single alanine to glycine point mutation suffices to more than double the
209 ic debridement, soft tissue curettage (STC), glycine powder air polishing (GPAP) and a repeated submu
210 ic debridement, soft tissue curettage (STC), glycine powder air polishing (GPAP), and a repeated subm
211 macologic inhibition of CSE with l-propargyl glycine prevented apneas in both HO-2(-/-) mice and SH r
212 ing amounts of gelatin increased circulating glycine, proline, hydroxyproline, and hydroxylysine, pea
214 ictly conserved glycine in collagen with aza-glycine provides a general solution for stabilizing trip
217 ng tfuA and/or ycaO revealed the presence of glycine, rather than thioglycine, supporting this hypoth
218 GLRB genes, which encode the alpha1 and beta glycine receptor (GlyR) subunits, are the major cause.
220 1 and contactin-associated protein-like 2), glycine receptor, and gamma-aminobutyric acid-A receptor
226 bition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of alpha1 a
227 irments or trafficking defects of inhibitory glycine receptors (GlyRs) have been linked to human hype
228 he shared stoichiometry for phasic and tonic glycine receptors suggests pharmacology is unlikely to b
231 was to evaluate the ability of gallic acid, glycine, reduced glutathione and l-cysteine at 0.1, 0.5,
232 e less responsive to depletion of serine and glycine, reflecting an ability of activated Kras to incr
234 Peptoids that are oligomers of N-substituted glycines represent a class of peptide mimics with great
236 cereblon through a surface turn containing a glycine residue at a key position, interacting with both
237 ith a one-residue stagger to fit every third glycine residue in the inner core without disturbing the
240 cated adjacent to the substitution sensitive glycine residues play a role in blocking the pathway upo
241 It contains four symmetrically arranged glycine residues suggesting that flexibility is a key fe
242 ApOmpA), an adhesin that uses key lysine and glycine residues to interact with alpha2,3-sialylated an
243 Upon combinatorial substitution of these glycine residues to proline, functional and structural a
245 that GABA co-release may speed the decay of glycine responses altering both temporal precision and s
246 el systems composed of adenine or adenosine, glycine, ribose and/or 2-furanmethanol (with and without
247 In addition, we identified variants of the glycine riboswitch class that no longer recognize this a
248 plex and the cytoskeletal-associated protein glycine-rich domain of Nip100/p150(glued) Our results su
250 lexes showed that the inhibitor stabilizes a glycine-rich loop conformation that shapes the ATP ribos
251 mbedded kinase by altering the dynamics of a glycine-rich motif that is critical for phosphotransfer
252 mple, the cardiac LIM protein, cysteine- and glycine-rich protein 3, is thought to mediate cardiac me
255 rtion of Aap contains a 135-aa-long, proline/glycine-rich region (PGR) that has not yet been characte
258 ty is tightly controlled by their regulatory glycine-serine rich (GS) domain adjacent to the kinase d
263 ole-2-carboxamido)propanoic acid (AICP) as a glycine site agonist with unique GluN2-dependent differe
265 istration of d-cycloserine (DCS), which is a glycine site NMDA receptor agonist, can enhance extincti
266 3 is a putative NMDA receptor modulator with glycine-site partial agonist properties that produces ra
267 pe (S54) and a susceptible genotype (S67) of Glycine soja, the wild progenitor of soybean, to underst
268 sed RNA-Seq data from seven Glycine subgenus Glycine species (three recently formed allotetraploids a
274 xA revealed allosteric cooperativity for its glycine substrate, but not O2 This is the first CTQ- or
275 A large amount of CO2 was detected from glycine-sucrose model system under coffee roasting condi
276 indicate that both enzymes favor the lauroyl glycine synthesis over the peptide synthesis, but the im
279 studies second stage juveniles of Heterodera glycines, the soybean cyst nematode (SCN), quickly migra
282 fer from S-adenosyl-l-methionine (AdoMet) to glycine to form S-adenosyl-l-homocysteine and sarcosine.
288 urrents dominate, blocking neuronal or glial glycine transporters enhances tonic glycinergic currents
289 king either, or both, the glial and neuronal glycine transporters markedly decreased PV+ IN excitabil
291 of proteins, in particular those containing glycine/tyrosine repeats that mediate formation of highe
292 show that this effect is rooted in defective glycine uptake in DLBCL cell lines, rendering them uniqu
294 ts of five structurally variant amino acids, glycine, valine, methionine, phenylalanine and cysteine
295 Diazo compounds derived from (p-methylphenyl)glycine were screened for the ability to esterify the gr
297 ure determination of a long unknown phase of glycine, which was first reported by Pyne and Suryanaray
300 cteriocin-like proteins CdzC and CdzD harbor glycine-zipper motifs, often found in amyloids, and CdzC
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