ライフサイエンスコーパス: glycine receptor

1 logous pair of cysteines on the human alpha1 glycine receptor.

2 ysis of a novel activation mechanism for the glycine receptor.

3 eby enabling complex formation of functional glycine receptors.

4 entify the stoichiometry of GluK2 and alpha1 glycine receptors.

5 e phyla but are closely related to mammalian glycine receptors.

6 ed that TXA and EACA inhibit the activity of glycine receptors.

7 metabotropic GABA(B) and ionotropic GABA(A)/glycine receptors.

8 se measured in the CSF of patients inhibited glycine receptors.

9 addition of GABA, a weak partial agonist of glycine receptors.

10 motif prevented PKC modulation of wild-type glycine receptors.

11 yric acid (GABA(A)), serotonin (5-HT(3)) and glycine receptors.

12 suggesting they were mediated by GABAa/c and glycine receptors.

13 ined phorbol ester modulation of GABA(A) and glycine receptors.

14 y influence from CVLM to RVLM is mediated by glycine receptors.

15 e A (GABA(A)), serotonin type 3 (5-HT3), and glycine receptors.

16 d significantly more charge than GABA(A) and glycine receptors.

17 tivity profile suggesting the involvement of glycine receptors.

18 tagonists of ionotropic glutamate, GABA, and glycine receptors.

19 d to block the activity of neuronal GABA and glycine receptors.

20 on, such as ring-like structures composed of glycine receptors.

21 receptor activation in homo- and heteromeric glycine receptors.

22 ed by the activation of GABA, glutamate, and glycine receptors.

23 ge in biophysical properties of postsynaptic glycine receptors.

24 ition are mediated by heteromeric alpha/beta glycine receptors.

25 280M, induced spontaneous activity in alpha1 glycine receptors.

26 of a low-affinity competitive antagonist at glycine receptors [2-(3-carboxypropyl)-3-amino-6-(4-meth

27 ypoxia alters the expression of the GABA and glycine receptors; 2) inhibitory amino acids change the

28 synaptic inhibition mediated by GABA(A) and glycine receptors, a biphasic effect of kainate is chara

29 bitory contributions of GABA(A), GABA(C) and glycine receptors across the BC pathways.

30 mportant functional moiety in the process of glycine receptor activation and allosteric regulation by

31 e cerebral cortex does not appear to require glycine receptor activity for proper development, as Glr

32 In the developing retina, inhibition of glycine receptor activity prevents proper rod photorecep

33 uroactive steroid 5alpha-THDOC and classical glycine receptor agonists beta-alanine and taurine direc

34 using a mixture comprising GABAA, GABAB, and glycine receptor agonists caused an immediate and tempor

35 gonist SR-95531 (gabazine) is known to block glycine receptors, albeit with low affinity.

36 The favourable properties of the glycine receptor allowed the first detection of a confor

37 Recently, glycine receptor alpha 1 antibodies have been described

38 Glycine receptor alpha 1 antibodies were found in serum

39 with rigidity and myoclonus associated with glycine receptor alpha 1 antibodies, a potentially sever

40 e generated mice with a targeted deletion of glycine receptor alpha 2 (Glra2).

41 During development, glycine receptor alpha 2 (GlyRalpha2) is expressed in th

42 econd transmembrane (TM) segment (M2) of the glycine receptor alpha(1) subunit (M2GlyR), including th

43 put analysis showed glycineric synapses with glycine receptor alpha1 expression between AII cells and

44 in-oligodendrocyte glycoprotein (MOG) or the glycine receptor alpha1 subunit (GlyR) is unclear.

45 an disease mutation in the M2-M3 loop of the glycine receptor alpha1 subunit (K276E) using direct fit

46 mutations, and large deletions in the human glycine receptor alpha1 subunit gene (GLRA1) are the maj

47 on, postembedding immunogold labeling of the glycine receptor alpha1 subunit showed that it was prese

48 A molecular model of the glycine receptor alpha1 subunit suggests that the Cys lo

49 henotype, has a point mutation (A52S) in the glycine receptor alpha1 subunit.

50 Glycine receptor alpha1-IgG aids identification of autoi

51 ved from the transmembrane M2 segment of the glycine receptor alpha1-subunit (M2GlyR) have been desig

52 Glycine receptor alpha1-transfected cells to test serum

53 co-localizing with monoclonal antibodies to glycine receptor-alpha1.

54 evidence is presented that signaling through glycine receptor alpha2 (GlyRalpha2) and GABA(A) recepto

55 ; 3alphaCOOH5betaP) on receptors composed of glycine receptor alpha3 subunits, expressed in Xenopus o

56 present a 3.0 A X-ray structure of the human glycine receptor-alpha3 homopentamer in complex with a h

57 omain and the transmembrane domain of alpha1 glycine receptor (alpha7-GlyR).

58 d bipolar cell axon terminals where GABA and glycine receptors also mediate light-evoked inhibition.

59 es are directed at inhibition of GABA(A) and glycine receptors, although GABA-independent effects hav

60 mains (TM23) of the alpha-1 subunit of human glycine receptor and its truncated form, both with the w

61 to alpha3-nAChR postsynaptic sites; synaptic glycine receptor and perisynaptic alpha7-nAChR clusters

62 s mentioned above, and other targets such as glycine receptors and mediators of neurotransmitter rele

63 prises a key energetic pathway in activating glycine receptors and other pLGICs.

64 ing the established activation mechanism for glycine receptors and our measurements of SR-95531 bindi

65 lly exclude calcium-gated chloride channels, glycine receptors and the chloride current associated wi

66 ing recruitment of postsynaptic gephyrin and glycine receptors and, to lesser extent, GABA(A) recepto

67 pressing GAD65, GAD67, alpha1-subunit of the glycine receptor, and a repertoire of known cell surface

68 1 and contactin-associated protein-like 2), glycine receptor, and gamma-aminobutyric acid-A receptor

69 ) between this pair of residues misfolds the glycine receptor, and in consequence, the protein is ret

70 es, alpha1, which forms most of the synaptic glycine receptors, and alpha3.

71 is inhibited by strychnine, an antagonist of glycine receptors, and bicuculline, an antagonist of GAB

72 e actions of glycine at strychnine-sensitive glycine receptors, and therefore GlyT1 antagonists also

73 cle nicotinic acetylcholine receptor and the glycine receptor-and find that the open-shut reaction is

74 The glycine receptor antagonist strychnine (4 microM) and th

75 The glycine receptor antagonist strychnine also prevented Et

76 BAa/c receptor antagonist picrotoxin and the glycine receptor antagonist strychnine did not affect ch

77 tor antagonists AP5 and CGP78608 but not the glycine receptor antagonist strychnine inhibited the CBF

78 eviously been shown to be a weak GABA(A) and glycine receptor antagonist.

79 receptors are inhibited, and is blocked by a glycine receptor antagonist.

80 were identified in 12 patients (11%), mainly glycine receptor antibodies (9 cases), which predominate

81 The glycine receptor antibodies activated complement on glyc

82 Glycine receptor antibodies are strongly associated with

83 Glycine receptor antibodies but not other cell surface a

84 The presence of glycine receptor antibodies did not correlate with any s

85 The clinical associations of glycine receptor antibodies have not yet been described

86 d levels; there was intrathecal synthesis of glycine receptor antibodies in each of the six pairs ava

87 Glycine receptor antibodies occur frequently in P-OMS wi

88 The presence of glycine receptor antibodies should help to identify a di

89 r; P = .02); however, a similar frequency of glycine receptor antibodies was found in patients with l

90 sin, GABA(A)-receptor-associated protein, or glycine receptor antibodies), neuromyotonia (Caspr2 anti

91 The 3 patients with glycine receptor antibody all improved with immunotherap

92 Serum glycine receptor antibody endpoint titres ranged from 1:

93 7 nmol/L; normal value, </= 0.02 nmol/L) and glycine receptor antibody in 3 cases.

94 Ten glycine receptor antibody positive samples were also ide

95 Glycine receptors are chloride-permeable, ligand-gated i

96 is known regarding the mechanism(s) by which glycine receptors are endocytosed.

97 Glycine receptors are ligand-gated chloride channels tha

98 type 3, gamma-amminobutyric acid type A, and glycine receptors are major players of human neuronal co

99 Inhibitory glycine receptors are pentameric ligand-gated ion channe

100 both the channel activity of NMDARs and the glycine receptors are pre-inhibited.

101 ration when their GABA(A), glutamate, and/or glycine receptors are stimulated, use glutamate and GABA

102 Glycine receptors are, in several ways, the member of th

103 rites that express the alpha3 subunit of the glycine receptor, as well as a subclass of unidentified

104 so identified glycine, acting via alpha-cell glycine receptors, as the predominant amino acid stimula

105 rnalization and lysosomal degradation of the glycine receptors at 37 degrees C.

106 ine and produces near-complete inhibition of glycine receptors at concentrations commonly employed to

107 ons are also found in the genes encoding the glycine receptor beta subunit (GLRB) and the presynaptic

108 Thus, the spastic allele of the murine glycine receptor beta subunit gene is a two-hit mutation

109 t (LINE1) retrotransposon in intron 6 of the glycine receptor beta subunit gene, Glrb(spa).

110 ibition, resembling conditions observed with glycine receptor blockade.

111 In the presence of a glycine receptor blocker, glycine and a substrate agonis

112 circuit activity was induced using GABA and glycine receptor blockers, which produced three rates of

113 he ON pathway and required gap junctions and glycine receptors but not ionotropic glutamate or GABA(A

114 annel recordings from rat recombinant alpha1 glycine receptors by fitting different mechanisms simult

115 Loss-of-function mutations in human glycine receptors cause hyperekplexia, a rare inherited

116 Since reduced function of glycine receptors causes seizures, we hypothesized that

117 ed a 73% increase in the open probability of glycine receptor channels in membrane patches of granule

118 binantly expressed homomeric and heteromeric glycine receptor channels, including their splice varian

119 ls a physio-molecular signature of homomeric glycine receptor channels, which provides unprecedented

120 Taurine, an agonist of glycine receptor chloride (GlyR Cl(-)) channels, was fou

121 it prevents surface expression of the alpha1 glycine receptor chloride channel.

122 We also report that glycine receptors cluster at GABAergic synapses in a sub

123 cytosis and also prevented PMA inhibition of glycine receptor currents.

124 The glycine receptor-deficient mutant mouse spastic carries

125 acutely, EtOH may reduce lOFC function via a glycine receptor dependent process and this may trigger

126 h GABAA (gamma aminobutyric acid type A) and glycine receptors depends on the presence of the neurona

127 calyx of Held synapse, in which presynaptic glycine receptors depolarize presynaptic terminals, elev

128 nates zinc potentiation of alpha1-containing glycine receptors develop severe sensorimotor deficits c

129 To investigate bilobalide's interaction with glycine receptors directly, we determined 36chloride flu

130 with the truncated N-terminal and C-terminal glycine receptor domains, functionality of the glycine r

131 sed protein-protein interaction between both glycine receptor domains.

132 The glycine receptor enables the generation of inhibitory po

133 s demonstrate that PKC activation stimulates glycine receptor endocytosis, that both constitutive end

134 Glycine receptors exhibit a biphasic sensitivity profile

135 urine acts via GlyRalpha2 subunit-containing glycine receptors expressed by retinal progenitor cells

136 examined the endocytosis of homomeric alpha1 glycine receptors expressed in HEK 293 cells using immun

137 ct of SR-95531 on rat recombinant alpha1beta glycine receptors expressed in human embryonic kidney (H

138 byproduct inhibits or activates human alpha1 glycine receptors expressed on the surface of HEK 293 ce

139 We found that axonal GABA but not glycine receptor expression depends on neurotransmission

140 ry amino acids change the course of GABA and glycine receptor expression; and 3) there are any differ

141 lycine KI mouse lines with markedly impaired glycine receptor function.

142 dependent domain demonstrated restoration of glycine receptor functionality in vitro.

143 members, nicotinic acetylcholine receptors, glycine receptors, GABA(A) receptors, serotonin-3 (5-HT(

144 ith the Cys loop to increase the efficacy of glycine receptor gating.

145 rose by genomic duplication of exon 5 in the glycine receptor gene Glra1.

146 porter 1; the anchoring protein for GABA and glycine receptors, gephyrin; the calcium binding protein

147 porter 1; the anchoring protein for GABA and glycine receptors, gephyrin; the calcium binding protein

148 Ivermectin (Ivm), a glycine receptor (GLR) agonist, was used to modulate cel

149 ons in the alpha-1 subunit of the inhibitory glycine receptor (GLRA1).

150 for subunits of the postsynaptic inhibitory glycine receptor, GLRA1 encoding the alpha1 subunit and

151 el (VGKC)-complex antigens in four patients, glycine receptor (GLY-R) in 5 patients, N-methyl-d-aspar

152 udies, taurine has been reported to activate glycine receptors (Gly-Rs) at moderate concentrations (>

153 glycinergic neurotransmission, including the glycine receptor (GlyR) alpha1 and beta subunits, gephyr

154 ssive hyperekplexia indicate disturbances in glycine receptor (GlyR) alpha1 biogenesis.

155 ominant and recessive mutations in the human glycine receptor (GlyR) alpha1 gene (GLRA1) are the majo

156 utations in the gene encoding the inhibitory glycine receptor (GlyR) alpha1 subunit (GLRA1).

157 ed inhibition was apparent for the homomeric glycine receptor (GlyR) alpha1 subunit compared to eithe

158 c alpha(1)-subunit (GLRA1) of the inhibitory glycine receptor (GlyR) and the cognate presynaptic glyc

159 The effect was blocked by the glycine receptor (GLyR) antagonist strychnine and mimick

160 systems, the GABA(A) receptor (GABA(A)R) and glycine receptor (GlyR) are described.

161 The glycine receptor (GlyR) exists either in homomeric alpha

162 way is largely blocked due to a reduction of glycine receptor (GlyR) expression, were quantitatively

163 Glycine receptor (GlyR) gating is initiated by agonist b

164 The glycine receptor (GlyR) is a member of the Cys-loop supe

165 The glycine receptor (GlyR) is a pentameric ligand-gated ion

166 The strychnine-sensitive glycine receptor (GlyR) mediates inhibitory synaptic tra

167 junctions, and provide inhibitory input via glycine receptor (GlyR) subunit alpha1 to OFF cone bipol

168 In contrast, the role of glycine receptor (GlyR) subunit-specific inhibition is l

169 GLRB genes, which encode the alpha1 and beta glycine receptor (GlyR) subunits, are the major cause.

170 rd transmembrane domains (TM23) of the human glycine receptor (GlyR) was achieved in low-q bicelles (

171 ically modified knock-in (KI) mouse having a glycine receptor (GlyR) with phenotypical silent mutatio

172 The pentameric glycine receptor (GlyR), a member of the nicotinicoid su

173 line receptor (nAChR) and the anionic alpha1 glycine receptor (GlyR), based on the structure of Torpe

174 e anion channels, such as CFTR, ANO1 and the glycine receptor (GlyR), by changing pore size.

175 or (CFTR), anoctamin-1(ANO1/TMEM16A) and the glycine receptor (GlyR), revealed that the ion selectivi

176 ed that ethanol enhances the activity of the glycine receptor (GlyR), thus enhancing inhibitory neuro

177 o N-methyl-d-aspartate receptor (NMDAR), the glycine receptor (GlyR), voltage-gated potassium channel

178 tracellular domain (ECD) of the human alpha1 glycine receptor (GlyR), with amino acids from the corre

179 und to contact principal output neurons, via glycine receptor (GlyR)-enriched synapses, virtually dev

180 ed, using whole-cell patch-clamp recordings, glycine receptor (GlyR)-mediated currents in spinal moto

181 environment of Cu(2)(+) in the human alpha1-glycine receptor (GlyR).

182 receptor (5-HT3AR) that is not found in the glycine receptor (GlyR).

183 tent potentiator at the strychnine-sensitive glycine receptor (GlyR).

184 proteins in the functional modulation of the glycine receptor (GlyR).

185 with strychnine, a blocker of the inhibitory glycine receptor (GlyR).

186 he alpha3beta4 AChR and the homomeric alpha1 glycine receptor (GlyR).

187 Glycine receptors (GlyR) are inhibitory Cys-loop ion cha

188 Strychnine-sensitive glycine receptors (GlyR) play a major role in the excita

189 s studies indicate that ethanol can modulate glycine receptors (GlyR), in part, through Gbetagamma in

190 We find that human islet beta-cells express glycine receptors (GlyR), notably the GlyRalpha1 subunit

191 tionally enhance the function of recombinant glycine receptors (GlyR).

192 GABAAR) and, to a lesser extent, by synaptic glycine receptors (GlyR).

193 n this case, the rat vanilloid (Trpv1 or the glycine receptor (GlyRalpha1), can allow selection of es

194 B1 bipolar cell axon terminals expressed the glycine receptor, GlyRalpha1, at sites of contact with A

195 eas a low-affinity competitive antagonist of glycine receptors (GlyRs) accelerated IPSC decay.

196 2 can markedly affect ethanol sensitivity in glycine receptors (GlyRs) and gamma-aminobutyric acid ty

197 sting propofol modulation of homomeric human glycine receptors (GlyRs) and nematode glutamate-gated c

198 Glycine receptors (GlyRs) and specific subtypes of GABA(

199 Inhibitory glycine receptors (GlyRs) are composed of homologous alp

200 Glycine receptors (GlyRs) are found in most areas of the

201 Glycine receptors (GlyRs) are inhibitory ligand-gated io

202 Previous studies suggested that glycine receptors (GlyRs) are involved in the regulation

203 Glycine receptors (GlyRs) are ligand-gated chloride chan

204 Glycine receptors (GlyRs) are major mediators of inhibit

205 Glycine receptors (GlyRs) are potentiated by ethanol and

206 Glycine receptors (GlyRs) are structurally related to GA

207 Although postsynaptic glycine receptors (GlyRs) as alphabeta heteromers attrac

208 ARs), GABA type B receptors (GABA(B)Rs), and glycine receptors (GlyRs) can be identified in patients

209 bition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of alpha1 a

210 The properties of glycine receptors (GlyRs) depend upon their subunit comp

211 receptors (GABAARs) and strychnine-sensitive glycine receptors (GlyRs) expressed by excitatory cortic

212 icrotoxin antagonism of the alpha1 homomeric glycine receptors (GlyRs) has been shown to be non-use-d

213 irments or trafficking defects of inhibitory glycine receptors (GlyRs) have been linked to human hype

214 have demonstrated the presence of functional glycine receptors (GlyRs) in hippocampus.

215 s (AMPARs) and increasing that of inhibitory glycine receptors (GlyRs) in synapses.

216 required to achieve a high concentration of glycine receptors (GlyRs) in the postsynaptic membrane,

217 Thus, taurine is a full agonist of the glycine receptors (GlyRs) in the VTA.

218 Glycine receptors (GlyRs) mediate inhibitory neurotransm

219 Strychnine-sensitive glycine receptors (GlyRs) mediate synaptic inhibition in

220 sidues in the extracellular loop 2 region of glycine receptors (GlyRs) or gamma-aminobutyric acid typ

221 face expression and regulated endocytosis of glycine receptors (GlyRs) play a critical function in ba

222 ereas both GABA(A) receptors (GABA(A)Rs) and glycine receptors (GlyRs) play a role in control of dors

223 is that several residues in Loop 2 of alpha1 glycine receptors (GlyRs) play important roles in mediat

224 ent phosphorylation of a specific subtype of glycine receptors (GlyRs) that contain alpha3 subunits.

225 nonpsychoactive cannabinoids can potentiate glycine receptors (GlyRs), an important target for nocic

226 ensitization of Cys-loop GABAA (GABAARs) and glycine receptors (GlyRs), which both mediate fast inhib

227 ma-aminobutyric acid receptors (GABAARs) and glycine receptors (GlyRs).

228 potential (AP) firing by activating neuronal glycine receptors (GlyRs).

229 omeric to predominantly mature alpha(1)/beta glycine receptors (GlyRs).

230 ous cannabinoids can allosterically modulate glycine receptors (GlyRs).

231 e and a competitive antagonist at ionotropic glycine receptors (GlyRs).

232 1) and heteromeric (alpha1beta1) subunits of glycine receptors (GlyRs).

233 ture IPSCs, suggesting a preterminal site of glycine receptors (GlyRs).

234 s area express Cl(-) permeable extrasynaptic glycine receptors (GlyRs).

235 of molecular mechanisms and pharmacology of glycine receptors has been hindered by a lack of high-re

236 nsmitter receptors (GABA, nACh, 5-HT(3), and glycine receptors) have resulted in a six-loop (A-F) mod

237 e kinetic properties of rat homomeric alpha3 glycine receptors heterologously expressed in HEK293 cel

238 mutations in the alpha1 subunit of the human glycine receptor (hGlyR) gene (GLRA1).

239 The human glycine receptors (hGlyRs) are chloride-selective ion ch

240 order of magnitude lower than the ionotropic glycine receptor in the same retina.

241 e the observation of diffusion of individual glycine receptors in living neurons and the identificati

242 nd western blotting revealed the presence of glycine receptors in lOFC.

243 no butyric acid (GABA) receptor subtypes and glycine receptors in mediating CVLM sympathoinhibition.

244 TXA and EACA are competitive antagonists of glycine receptors in mice.

245 clude that bilobalide does not interact with glycine receptors in neurochemical assays but it signifi

246 ially regulate the expression of GABA(A) and glycine receptors in rat cortical neurons under normoxic

247 of breathing pattern by blocking GABA(A) and glycine receptors in the preBotzinger complex (preBotC),

248 role in forming the mature heteropentameric glycine receptors in these brain stem nuclear groups.

249 ion of gamma-aminobutyric acid (GABA)(A) and glycine receptors inhibits neurons as a result of low in

250 The glycine receptor is a target for both alcohols and anest

251 demonstrate that constitutive endocytosis of glycine receptors is blocked by the dominant negative dy

252 inhibitory central nervous system GABAA and glycine receptors, is believed to interact with residues

253 Because ws-LYNX1 was inactive against glycine receptor, its "non-classical" binding sites on a

254 ce, and it persisted while blocking GABA and glycine receptors, K((Ca)) channels, or mGluRs.

255 Inherited defects in glycine receptors lead to hyperekplexia, or startle dise

256 s necessary for the depolarizing response to glycine receptor ligands.

257 is the first time that two TM domains of the glycine receptor linked by the important 23 loop have ev

258 To determine whether GABA(A), GABA(C) and glycine receptors made different contributions to light-

259 and suggest that TXA-mediated inhibition of glycine receptors may underlie the effect.

260 at GlyRalpha2, the developmentally expressed glycine receptor, may play an important role in neuronal

261 Glycine receptors mediate fast synaptic inhibition in sp

262 We show that GABA(A), GABA(C) and glycine receptors mediate functionally distinct inhibiti

263 extent propofol, reverses TXA inhibition of glycine receptor-mediated current, suggesting that these

264 eurons are cut off from GABA(B), GABA(A) and glycine receptor-mediated inhibition.

265 ntrast, the frequency of spontaneous GABA(A)/glycine receptor-mediated inhibitory postsynaptic synapt

266 gamma-aminobutyric acid type A receptor- and glycine receptor-mediated signaling that characterizes n

267 G93A) mice to investigate the development of glycine-receptor-mediated synaptic currents recorded fro

268 The glycine receptor mediates fast synaptic inhibition in th

269 e examine the properties of a range of novel glycine receptor mutants identified in human hyperekplex

270 ycinergic transmission by acting directly on glycine receptors, narrowing the time window for effecti

271 Our results suggest that glycine receptors on ventral horn neurones in the juveni

272 (two nicotinic acetylcholine receptors, two glycine receptors, one GABA receptor, two AMPA-type glut

273 r GluN2B subunits AMPA, kainate, and GABA or glycine receptors or a variety of other potential target

274 nAChRs but not with the neighboring synaptic glycine receptors or perisynaptic alpha7-nAChRs on chick

275 In both muscle nicotinic and glycine receptors, partial agonists are as good as full

276 Analysis of the glycine receptor properties mediating inhibition of parv

277 napses on RCs correlates well with increased glycine receptor recruitment to large gephyrin patches,

278 we demonstrate that inhibition of a specific glycine receptor subtype (GlyR alpha3) by PGE2-induced r

279 ease and postsynaptic expression of GABA and glycine receptor subtypes.

280 is correlates with a change in glutamate and glycine receptor subunit composition quantified via mRNA

281 that the inhibition is marked by a switch in glycine receptor subunits from neonatal to adult form ar

282 Expression of GABA(A), GABA(C) and glycine receptor subunits was confirmed by RT-PCR.

283 gamma-aminobutyric acid type A (GABA(A)) and glycine receptor subunits.

284 he shared stoichiometry for phasic and tonic glycine receptors suggests pharmacology is unlikely to b

285 uggest that a UCA-induced down-regulation of glycine receptor synthesis may have occurred via reduced

286 Truncated glycine receptors that have been found in human patients

287 Ames medium and after blocking GABA(A/C) and glycine receptors, that PCP2-null rod bipolar cells were

288 hibitory amino acids is mediated by GABA and glycine receptors, the expression of these receptors is

289 synaptic currents can be mediated by alpha3 glycine receptors, they are likely to be very close in t

290 tly determine the subunit stoichiometry of a glycine receptor to be 3alpha1:2beta.

291 ression and correct orientation according to glycine receptor topology.

292 receptor antibodies activated complement on glycine receptor-transfected human embryonic kidney cell

293 ycine receptor domains, functionality of the glycine receptor was again restored.

294 Unlike GABA(A)Rs, synaptic clustering of glycine receptors was completely abolished in gephyrin-/

295 data on gamma-aminobutyric acid, type A, and glycine receptors, we concluded that the overall chargin

296 By applying glycine to native or recombinant glycine receptors, we show that response decay times are

297 c response was not found although functional glycine receptors were demonstrated at E16.

298 he interaction found between subunits of the glycine receptor while it is still shut and, perhaps, th

299 Calyces express presynaptic glycine receptors whose activation depolarizes the synap

300 The fast unbinding rate of SR-95531 from the glycine receptor will make it useful for establishing th