ライフサイエンスコーパス: glycolaldehyde

1 s: 4-hydroxy-2-nonenal, malondialdehyde, and glycolaldehyde.

2 experiments, starting with formaldehyde and glycolaldehyde.

3 ase activity toward beta-hydroxypyruvate and glycolaldehyde.

4 ford, MA) was nonenzymatically glycated with glycolaldehyde.

5 amples with (13)C- and (2)H-labeled forms of glycolaldehyde.

6 inobenzene protected against the toxicity of glycolaldehyde.

7 rin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.

8 the substrate, HOCl generates high yields of glycolaldehyde.

9 catalyzed reactions of GAP and of [1-(13)C]-glycolaldehyde ([1-(13)C]-GA) in D(2)O is reported.

10 on of the truncated substrate piece [1-(13)C]glycolaldehyde ([1-(13)C]-GA) in D(2)O, a 25-fold increa

11 the deuterium exchange reactions of [1-(13)C]glycolaldehyde ([1-(13)C]GA) to form [1-(13)C,2-(2)H]GA

12 The generation of glycolaldehyde, 2-hydroxypropanal, and acrolein by activ

13 In vitro studies have demonstrated that glycolaldehyde, a product of serine oxidation, reacts wi

14 organic aerosol production was observed for glycolaldehyde, acetaldehyde, and formaldehyde only at e

15 ylglyoxal, glyceraldehyde, dihydroxyacetone, glycolaldehyde, acetaldehyde, glyoxal, glyoxylic acid, a

16 Glycolaldehyde also inactivates ethanolamine ammonia-lya

17 ine ammonia-lyase reveal that treatment with glycolaldehyde also results in formation of an ethanesem

18 Activated neutrophils converted L-serine to glycolaldehyde, an alpha-hydroxyaldehyde which mediates

19 onstitutional chemical relationships between glycolaldehyde and beta-mercapto-acetaldehyde, and the c

20 membrane-like matrix, was cross-linked with glycolaldehyde and control and cross-linked matrices com

21 onucleotide precursor-is readily formed from glycolaldehyde and cyanamide, so is 2-aminothiazole form

22 rmation, the important nucleotide precursors glycolaldehyde and glyceraldehyde in a stable, crystalli

23 that simple two- and three-carbon molecules (glycolaldehyde and glyceraldehyde), in the presence of a

24 the sugar building blocks for the synthesis--glycolaldehyde and glyceraldehyde--could be shown to der

25 ed 10 aldehydes, including the sugar-related glycolaldehyde and glyceraldehyde--two species considere

26 ruvate from prebiotic nucleotide precursors, glycolaldehyde and glyceraldehyde.

27 )K(GA) for reactions of the substrate pieces glycolaldehyde and HPO3(2-) have been determined for wil

28 The in vivo production of glycolaldehyde and other reactive aldehydes by myelopero

29 (cat)/K(m))DHAP] and of the substrate pieces glycolaldehyde and phosphite dianion (k(cat)/K(HPi)K(GA)

30 AP into the minimal neutral two-carbon sugar glycolaldehyde and phosphite dianion pieces.

31 l was approximately 10 times more toxic than glycolaldehyde and was more toxic to the SOD-null strain

32 ius 1 mm) containing iron(III), oxalic acid, glycolaldehyde, and ammonium sulfate (pH approximately 3

33 mixture of Nalpha-tert-butoxycarbonyllysine, glycolaldehyde, and glyceraldehyde could produce the Nal

34 e aldehydes (e.g., glyoxylate, formaldehyde, glycolaldehyde, and glyceraldehyde) in water were invest

35 Glyoxal, methylglyoxal, glycolaldehyde, and hydroxyacetone form N-containing and

36 rate constant (kcat/Km)obsd for turnover of glycolaldehyde, and the dependence of (kcat/Km)obsd on [

37 Similar experiments on glycolaldehyde- and hydroxyacetone-methylamine aerosol f

38 -glyceraldehyde, methylglyoxal, glyoxal, nor glycolaldehyde, are precursors.

39 This study utilizes glycolaldehyde as a model organic species to examine the

40 of primitive fatty acid synthesis that uses glycolaldehyde as a substrate.

41 as targets for superoxide was examined using glycolaldehyde as the simplest sugar and using superoxid

42 tmosphere by reaction with (*)OH and O2 with glycolaldehyde being identified as a previously unconsid

43 carboxylic acids from tetroses, trioses, and glycolaldehyde, but cannot readily catalyze retro-aldol

44 activation of hlGPDH-catalyzed reduction of glycolaldehyde by FPO3(2-) to -3.0 kcal/mol for activati

45 a give kcat/Km = 185 M-1 s-1 for turnover of glycolaldehyde by TIM that is saturated with phosphite d

46 thane) and minor products (ethanol, glyoxal, glycolaldehyde, ethylene glycol, acetaldehyde, ethane, a

47 were prepared from 2 by a condensation with glycolaldehyde followed by tandem reductive amination of

48 2-)) activated hydride transfer from NADL to glycolaldehyde (GA) catalyzed by glycerol-3-phosphate de

49 se in k(cat)/K(m) for isomerization of bound glycolaldehyde (GA), although the dominant observed prod

50 s no detectable activity toward reduction of glycolaldehyde (GA), or activation of this reaction by 3

51 ction of carbonyl compounds glyoxal (GO) and glycolaldehyde (GLA) with pyridoxamine (PM), a potent po

52 DHAP) and of the neutral truncated substrate glycolaldehyde (GLY) by glycerol 3-phosphate dehydrogena

53 for the synthesis-cyanamide, cyanoacetylene, glycolaldehyde, glyceraldehyde and inorganic phosphate-a

54 Glycolaldehyde-glycine mixtures produced the most intens

55 ng the release of formaldehyde, formic acid, glycolaldehyde, glyoxal, acetic acid, glycolic acid, gly

56 d hydroxynonenal) or carbohydrate oxidation (glycolaldehyde, glyoxal, and methylglyoxal) covalently m

57 followed the order methylglyoxal > glyoxal > glycolaldehyde > hydroxyacetone.

58 Glycolaldehyde (HOCH(2)CH horizontal lineO) is the small

59 almost exclusive HO2(*) elimination to form glycolaldehyde (HOCH2CHO).

60 st step or steps of the catalytic process on glycolaldehyde hydrate generate an intermediate that und

61 ion proceeds by a radical mechanism, and the glycolaldehyde hydrate is expected to be converted initi

62 The carbon atoms of glycolaldehyde hydrate remain bound to this complex, and

63 followed the order methylglyoxal > glyoxal > glycolaldehyde = hydroxyacetone, likely caused by the sp

64 methods to ionize known pyrolysis products: glycolaldehyde, hydroxyacetone, furfural, 5-hydroxymethy

65 ave been developed; alkynyl boronates add to glycolaldehyde imine to afford allylic hydroxyl allenes,

66 TIM catalyzes proton transfer from glycolaldehyde in D2O, resulting in deuterium incorporat

67 The hydrate of glycolaldehyde is a substrate analogue that induces the

68 ceraldehyde by reaction of formaldehyde with glycolaldehyde is catalyzed under prebiotic conditions t

69 Glycolaldehyde is found to undergo rapid oxidation to fo

70 alysis of the inactivated complex shows that glycolaldehyde is transformed into a cis-ethanesemidione

71 rmose reaction, formaldehyde is converted to glycolaldehyde, its dimer, under credible prebiotic cond

72 e Tbb TIM and monoTIM-catalyzed reactions of glycolaldehyde labeled with carbon-13 at the carbonyl ca

73 Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl ca

74 ms of the peptide catalyst and the C1 of one glycolaldehyde molecule.

75 ber explore the reactive uptake of gas-phase glycolaldehyde onto aqueous seed aerosol containing iron

76 from 0 to 12 weeks or for up to 3 days with glycolaldehyde or glyoxylic acid.

77 w aldol condensation of dihydroxyacetone and glycolaldehyde phosphate with an initial k(cat) of 1.6 x

78 ge to the enediolate of dihydroxyacetone and glycolaldehyde phosphate, followed by rotation of the al

79 The uptake of 80 (+/-10) ppb glycolaldehyde produced 2-4 wt % organic aerosol mass in

80 s such as N(epsilon)-carboxymethyllysine and glycolaldehyde-pyridine.

81 prebiotic model of sugar synthesis involving glycolaldehyde self-condensation, we demonstrate that ho

82 The glycolaldehyde that partitioned into the aerosol liquid

83 uctose-6-phosphate a physiological donor and glycolaldehyde the best non-phosphorylated acceptor.

84 The ions were shown to be glycopyranosyl-glycolaldehydes through chemical synthesis of their stan

85 esults indicate that the reaction pathway of glycolaldehyde to produce syngas can be enhanced by supp

86 Glycolaldehyde was more toxic to the SOD-null strain tha

87 The aggregation of the smallest sugar, glycolaldehyde, was studied in a conformer-selective man

88 The reactive uptake and aqueous oxidation of glycolaldehyde were examined in a photochemical flow rea

89 th slope and intercept effects versus varied glycolaldehyde were produced, indicating that TPCK react

90 dihydroxy acetone, and the two carbon sugar glycolaldehyde, were similarly toxic in an O-2-dependent

91 small aldehydes (glyoxal, methylglyoxal, and glycolaldehyde) with ammonium sulfate and amines are com