ライフサイエンスコーパス: glycolysis

1 of HIF-1alpha targets involved in anaerobic glycolysis.

2 le changes from fatty acid beta-oxidation to glycolysis.

3 nsatory increase in fatty acid oxidation and glycolysis.

4 h likely influences both gluconeogenesis and glycolysis.

5 sm characterized by a preference for aerobic glycolysis.

6 drial oxidative phosphorylation and enhanced glycolysis.

7 Ectopic LKB1 reduced HK-II along with glycolysis.

8 for a constant supply of NAD, a co-factor in glycolysis.

9 fied as a potential contributor to increased glycolysis.

10 ithelial cells, to evaluate the relevance of glycolysis.

11 ax; metabolic tumor volume; and total lesion glycolysis.

12 e mechanisms underlying abnormal endothelial glycolysis.

13 ch from oxidative phosphorylation to aerobic glycolysis.

14 abolic flux through allosteric regulation of glycolysis.

15 switch between oxidative phosphorylation or glycolysis.

16 l migration, which relies instead on aerobic glycolysis.

17 on of miR-124, increased PTPB1, and enhanced glycolysis.

18 hat sustains rapid glucose breakdown through glycolysis.

19 ith enhanced hypoxic responses and increased glycolysis.

20 e-level phosphorylation, gluconeogenesis and glycolysis.

21 rom oxidative phosphorylation to accelerated glycolysis.

22 ance 4 (BCAR4) is required for YAP-dependent glycolysis.

23 KATPHI islets, suggesting increased rates of glycolysis.

24 rg-like switch of their metabolism to higher glycolysis.

25 ozyme 2 (PKM2) is a key regulator of aerobic glycolysis.

26 lin-stimulated mitochondrial respiration and glycolysis.

27 okines and chemokines, and genes controlling glycolysis.

28 fold (from 3.5 to 0.36 mm), thus influencing glycolysis.

29 ning, expression of antimicrobial genes, and glycolysis.

30 role for this factor in regulating anaerobic glycolysis.

31 porter Glut1 expression, glucose uptake, and glycolysis.

32 ases SIRT6 deacetylase activity and promotes glycolysis.

33 the cellular energy charge coordinately with glycolysis.

34 beled pyruvate and lactate, originating from glycolysis.

35 osphoglycerate mutase 1 (PGAM1) functions in glycolysis.

36 uctokinase 1 (PFK1) plays a critical role in glycolysis.

37 ciency, mammalian cells up-regulated aerobic glycolysis, a process mediated by AMP-activated protein

38 og signaling to enhance the transcription of glycolysis activators HK2 and PFKFB3.

39 This highly regulated form of glycolysis allows cells to efficiently budget their meta

40 Glycolysis also appeared altered following As(III) stres

41 ole in SIRT6-dependent control over monocyte glycolysis, an important determinant of effector innate

42 sed and ectopic expression of LKB1 decreased glycolysis, anchorage-independent cell growth, and cell

43 In addition, glycolysis and amino acid metabolism were significantly

44 1-deficient macrophages, including increased glycolysis and an accumulation of long chain acylcarniti

45 phenotypic switch characterized by enhanced glycolysis and an altered cytokine secretion (interleuki

46 oxidation, as confirmed by reduced anaerobic glycolysis and an increased oxygen consumption ratio.

47 to dissect the relationship between aerobic glycolysis and anabolic metabolism in the retinas of mic

48 he down-regulation of several key enzymes in glycolysis and ATP production.

49 , we find that lncRNA H19 is responsible for glycolysis and BCSC maintenance.

50 Lastly, aspirin markedly attenuates glycolysis and cancer stem-like characteristics by suppr

51 Overall, glycolysis and cortical translocation are functionally d

52 The expression of genes involved in glycolysis and DNL, including that of two ChREBP isoform

53 witch from oxidative phosphorylation towards glycolysis and enhanced glucose uptake.

54 Aerobic glycolysis and enhanced reliance on glutamine utilizatio

55 e that 1.62% dietary arginine level improves glycolysis and fatty acid synthesis in juvenile blunt sn

56 evisiae metabolizes glucose predominantly by glycolysis and fermentation.

57 ges the sugar uptake, although all genes for glycolysis and gluconeogenesis, including bifunctional u

58 ize with other rate-limiting enzymes in both glycolysis and gluconeogenesis, supporting the formation

59 uman cancer cells suppressed open chromatin, glycolysis and Glut1 expression levels.

60 Thus, a primary function of aerobic glycolysis and glutaminolysis is to co-operatively limit

61 Glycolysis and glutaminolysis, but not FAS, inhibit vira

62 g that allows activated T cells to switch to glycolysis and glutaminolysis.

63 Cancer cells exhibit high rates of glycolysis and glutaminolysis.

64 conditions and link intrinsic regulation of glycolysis and glycogen stores to the resolution of neut

65 nd reserve respiratory capacity, and greater glycolysis and glycolytic reserve.

66 a axis as an important pathway in regulating glycolysis and hypoxic adaptation in tumor cells.

67 eports the proportion of ATP production from glycolysis and identifies cells as primarily glycolytic

68 lls and metabolic profiling reveals elevated glycolysis and increased mTORC1 signalling.

69 eas IPF fibroblasts are enriched for aerobic glycolysis and innate immune receptor activation, innate

70 pif-/- male and female mouse kidneys towards glycolysis and Krebs cycle activity.

71 elevated and KIN10 is inhibited; conversely, glycolysis and lipid biosynthesis are curtailed as sugar

72 transcription factors, positively regulates glycolysis and lipid biosynthesis in Arabidopsis thalian

73 supplies cytosolic acetyl-CoA and plastidic glycolysis and malic enzyme support the formation of pla

74 E2F1 targets included glycolysis and metabolic genes including CKB that enable

75 of Myc, a transcription factor that controls glycolysis and metabolic reprogramming.

76 the primary metabolic checkpoint connecting glycolysis and mitochondrial oxidative phosphorylation a

77 The relative fluxes through glycolysis and nucleotide metabolism pathways were consi

78 ) is a key signaling molecule resulting from glycolysis and other metabolic pathways.

79 etabolic phenotype characterized by elevated glycolysis and oxidative metabolism as well as augmented

80 erated from basic cellular processes such as glycolysis and oxidative phosphorylation also contribute

81 Glycolysis and oxidative phosphorylation are the fundame

82 Partitioning of ATP generation between glycolysis and oxidative phosphorylation is central to c

83 for the two main sources of ATP production, glycolysis and oxidative phosphorylation, in fueling pre

84 le entry of quiescent T cells by controlling glycolysis and oxidative phosphorylation.

85 glycolytic ATP production to alterations in glycolysis and oxidative reactions, respectively; the su

86 s, respectively, to quantify the activity of glycolysis and OXPHOS.

87 aling plays an important role in HDM-induced glycolysis and pathogenesis of allergic airways disease.

88 HDM or IL-1beta and required for HDM-induced glycolysis and pathogenesis of allergic airways disease.

89 on of B cell size, mitochondrial biogenesis, glycolysis and production of reactive oxygen species (RO

90 down-regulates metabolic pathways, including glycolysis and pyruvate metabolism.

91 etic analysis, we discovered that DF induces glycolysis and reduces mitochondrial respiratory capacit

92 f PI3K-AKT-mTOR signaling markedly decreased glycolysis and restrained tumor growth, these signaling

93 nd ablation of PDK1 counteracts H19-mediated glycolysis and self-renewal ability in vitro and in vivo

94 hancing DDR and DNA repair through promoting glycolysis and subsequent chromatin remodeling.

95 doreductases from central carbon catabolism (glycolysis and TCA cycle), and was controlled by cAMP-Cr

96 The increase of glycolysis and the abnormal mitochondrial metabolic pote

97 ygen, suggesting an enhanced activity of the glycolysis and the cellular respiration.

98 Glycolysis and the pentose phosphate pathway both play a

99 Thus, glycolysis and the TCA cycle are uncoupled at the level

100 unction ofTgPEPCKmt in cohesive operation of glycolysis and the tricarboxylic acid cycle in a normal

101 lly, metabolic profiling suggested that both glycolysis and the tricarboxylic acid cycle were suppres

102 R inhibition led to changes in the levels of glycolysis and tricarboxylic acid (TCA) cycle pathway in

103 ncluding many intermediates derived from the glycolysis and tricarboxylic acid cycle pathways.

104 As) targeting BCAR4 attenuated YAP-dependent glycolysis and tumor growth.

105 s a safeguard against HPV-stimulated aerobic glycolysis and tumor progression.

106 biosynthesis implies a selection for aerobic glycolysis and uncoupling biosynthesis from NADH generat

107 at this entire lineage of pathogens has lost glycolysis and, uniquely amongst eukaryotes, lacks any o

108 is glucose, from which ATP is generated via glycolysis and/or oxidative metabolism.

109 inefficient energy production (i.e., aerobic glycolysis) and depletion of resources for adaptations t

110 umor regions are constrained by low-yielding glycolysis, and any means of reducing the cost of acid e

111 chia coliPgi catalyzes the first reaction in glycolysis, and its loss results in major physiological

112 ed cytosolic calcium ([Ca(2+)]cyto), aerobic glycolysis, and mitochondrial fission.

113 tects EC from lipotoxic stress, regulates EC glycolysis, and provides a source of FA for adjacent cel

114 n acidic environment via upregulated aerobic glycolysis; and (ii) noninvasive cells that were angioge

115 tracellular acidification rate, a measure of glycolysis, are both greater in CTB than in SCT in vitro

116 ntexts, we identified PI3K/Akt regulation of glycolysis as a multifaceted modulator of single-cell me

117 in a shift from oxidative phosphorylation to glycolysis as the preferred mode of energy generation, t

118 reversibly induced a metabolic shift toward glycolysis as well as mitochondrial remodeling and led t

119 posal of methylglyoxal, a toxic byproduct of glycolysis, as 1-propanol.

120 A block in glycolysis associated with monocyte deactivation by endo

121 Rapidly proliferating cells increase glycolysis at the expense of oxidative phosphorylation (

122 therapeutic potential of targeting YAP-BCAR4-glycolysis axis for breast cancer treatment.

123 K1), which is considered the "gatekeeper" of glycolysis because it catalyzes the step committing gluc

124 sphosphoglycerate into 3-phosphoglycerate in glycolysis but also participates in the reverse reaction

125 an important function of NAC1 in regulating glycolysis, but also identifies the NAC1-HDAC4-HIF-1alph

126 eases lactate efflux as a result of enhanced glycolysis, but it also enhances gluconeogenesis from la

127 mary, basal transmission can be sustained by glycolysis, but strong presynaptic demands are met prefe

128 tes oxidation of NADH and supports increased glycolysis by generating NAD(+), a substrate for GAPDH-m

129 1.62% dietary arginine level upregulated glycolysis by increasing GK mRNA level; 2.70% dietary ar

130 o mesenchymal transition, increasing aerobic glycolysis by upregulating the glycolytic enzymes hexoki

131 The metabolic rewiring of glycolysis can circumvent the normally lethal effects of

132 Glycolysis can provide energy and glutaminolysis can pro

133 Parasites with an intact glycolysis can tolerate genetic deletions of TgPEPCKmt a

134 ed movement of the first four enzymes of the glycolysis cascade: hexokinase, phosphoglucose isomerase

135 GAPDH and PGK, two sequential enzymes in the glycolysis catalytic cycle.

136 creases PFKP expression and promotes aerobic glycolysis, cell proliferation, and brain tumor growth.

137 rboxylase (TgPyC) is dispensable not only in glycolysis-competent but also in glycolysis-deficient ta

138 nd genetic inhibition of either mitophagy or glycolysis consistently inhibited RGC differentiation.

139 TgPEPCKnet can also be ablated in a glycolysis-deficient mutant, while TgPEPCKmt is refracto

140 not only in glycolysis-competent but also in glycolysis-deficient tachyzoites despite a mitochondrial

141 demonstrated a shift in energy production to glycolysis, despite an inability to increase glucose upt

142 , increased KI67 labeling index, upregulated glycolysis, DNA repair, mTORC1 signaling, features of th

143 olic enzymes are presumed regulators of this glycolysis-driven metabolic program, known as the Warbur

144 ng from oxidative phosphorylation to aerobic glycolysis, during which glucose is converted into lacta

145 uced mitochondrial respiration and increased glycolysis, energy expenditure, and fat metabolism.

146 dehydrogenase 1 (GAPDH1), which is primary a glycolysis enzyme but actually a quintessential multifun

147 n metabolism and morphogenesis, showing that glycolysis facilitates body elongation and balances neur

148 NAD(+)-sensitive pathways, such as glycolysis, flux through lactate dehydrogenase, and the

149 Endothelial cells typically rely on aerobic glycolysis for angiogenesis.

150 r cells were considered to utilize primarily glycolysis for ATP production, referred to as the Warbur

151 rmittent exercise relies less upon anaerobic glycolysis for ATP provision than continuous exercise; s

152 ow faster cancer cells must activate aerobic glycolysis for energy generation and uncouple NADH gener

153 uction, and effector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic fea

154 d IGF-1R activity became highly dependent on glycolysis for survival.

155 Tumor cells preferentially adopt aerobic glycolysis for their energy supply, a phenomenon known a

156 show that rod photoreceptors in mice rely on glycolysis for their outer segment biogenesis.

157 (PFKL), which catalyzes a bottleneck step of glycolysis, forms various sizes of cytoplasmic clusters

158 s, these novel findings demonstrate that the glycolysis gatekeeper PDK1 has a critical role in BCSC r

159 glycolytic flux, glucose use, expression of glycolysis genes, and lactate production.

160 t gene expression, whereas mRNAs involved in glycolysis, gluconeogenesis, and T cell activation were

161 se groups, including metabolites involved in glycolysis, gluconeogenesis, lipid metabolism, citric ac

162 -320a, -193b-3p, and -92b-3p co-regulate the glycolysis/gluconeogenesis and focal adhesion in cancers

163 binding of PPARalpha near genes involved in glycolysis/gluconeogenesis and uncovered a role for this

164 ogs demonstrated significant upregulation of glycolysis/gluconeogenesis intermediates (e.g., glucose/

165 tophan biosynthesis, ribosome biogenesis and glycolysis/gluconeogenesis were significantly associated

166 y lysine 2-hydroxyisobutyrylation, including glycolysis/gluconeogenesis, TCA cycle, starch biosynthes

167 reported in human T1D (e.g., alterations in glycolysis/gluconeogensis metabolites, bile acids, and e

168 strating how inhibitors of metabolism (e.g., glycolysis, glutamine metabolism, and fatty acid oxidati

169 We found that glycolysis, glutaminolysis, and FAS are all required for

170 s multiple metabolic pathways, including the glycolysis, glutaminolysis, and fatty acid synthesis (FA

171 rs of cellular metabolic pathways, including glycolysis, glutaminolysis, and fatty acid synthesis.

172 posure for 48 hours resulted in reduction in glycolysis, glutaminolysis, the citric acid (TCA) cycle

173 tion of the NAD required to support enhanced glycolysis has been attributed to the terminal glycolyti

174 The ability of neurons to up-regulate glycolysis has, however, been debated.

175 show that distal and proximal disruptions of glycolysis have opposite effects on proliferation, and t

176 pped significantly with gene sets related to glycolysis, hypoxia, and a colon cancer cell phenotype,

177 of a conditional mutant of TgPEPCKmt in the glycolysis-impaired strain was aborted upon induced repr

178 We also show the role of NAC1 in promoting glycolysis in a mouse xenograft model, and demonstrate t

179 Glucose transport and glycolysis in activated CD4(+) T cells were compromised

180 lthough Otto Warburg first described aerobic glycolysis in cancer cells >90 years ago, the primary pu

181 the expression levels of Glut1 and inhibited glycolysis in cancer cells.

182 e Warburg effect that describes an increased glycolysis in cancer cells.

183 1 isoform is considered critical for aerobic glycolysis in cancer cells.

184 ide phosphoribosyltransferase and stimulates glycolysis in cardiomyocytes.

185 LDH, which is a non-limiting enzyme of glycolysis in differentiated cells, was tightly regulate

186 induced retinopathy mouse model by promoting glycolysis in endothelial cells via the ERK/Akt/HIF-1alp

187 g of PTPB1 restored normal proliferation and glycolysis in heritable PAH BOECs, corrected the dysregu

188 Its central role in regulating glycolysis in human sarcomas was evaluated by short- and

189 Clinically, elevated GLUT1-mediated glycolysis in lung SqCC strongly correlates with high (1

190 Our data suggest that forcing tumor glycolysis in melanoma using zalcitabine or other simila

191 ion of lactate production, and inhibition of glycolysis in MiaPaCa2 pancreatic cancer and A673 sarcom

192 lcium Uptake 1 (MICU1/CBARA1) drives aerobic glycolysis in ovarian cancer.

193 ally nothing is known about the relevance of glycolysis in patients with allergic asthma.

194 ults from their limited capacity to increase glycolysis in response to metabolic stresses.

195 We examined alterations in glycolysis in sputum samples from asthmatic patients and

196 This evidence strongly suggests that glycolysis in the cilia and knob oxidative phosphorylati

197 ence and functionality of glucose uptake and glycolysis in the cilia.

198 ote oxidation of NADH to facilitate enhanced glycolysis in the cytosol and that pioglitazone may regu

199 esis in the fasted state and lipogenesis and glycolysis in the fed state.

200 de evidence for spatiotemporal regulation of glycolysis in the posterior region of mouse and chicken

201 Our results suggest that glycolysis in the tail bud coordinates Wnt and FGF signa

202 Sustained augmentation of glycolysis in TLR-primed cells was dependent, in part, o

203 isoenzyme M2 (PKM2), a critical regulator of glycolysis in tumors, as a target that CHIP mediated for

204 his unique method allows direct detection of glycolysis in vivo in the healthy brain in a noninvasive

205 increases oxidative capacities and decreases glycolysis, in association with a decreased pentose phos

206 ociated with tumour cell reliance on aerobic glycolysis, in promoting tumour cell exosome release.

207 This limits glycolysis, increases oxidative phosphorylation, and is

208 the increase in nephrogenesis observed after glycolysis inhibition.

209 bolites and an increased sensitivity towards glycolysis inhibition.

210 nuclear cells (PBMCs) in the presence of the glycolysis inhibitor 2-deoxyglucose and radiation treatm

211 ve to inhibition by 1 in the presence of the glycolysis inhibitor 2-deoxyglucose.

212 ger a dynamic metabolic flux conversion from glycolysis into acetate synthesis to stimulate the jasmo

213 hus, FGF-dependent regulation of endothelial glycolysis is a pivotal process in developmental and adu

214 Our findings suggest that glycolysis is a pivotal, cell-intrinsic determinant of N

215 We sought to determine whether glycolysis is altered in patients with allergic asthma a

216 ional consequences of MPI loss are striking: glycolysis is blocked and cells die.

217 Glycolysis is critical for cancer stem cell reprogrammin

218 etic activity could be a plant strategy when glycolysis is impaired to achieve metabolic adjustment a

219 Glycolysis is necessary for early gene transcription, wh

220 racellular replication but we confirmed that glycolysis is not strictly essential.

221 We have previously shown that aerobic glycolysis is required for the regulated proliferation o

222 Direct modulation of glycolysis is sufficient to change gammadelta IEL behavi

223 hondrial function, oxygen consumption rates, glycolysis, lactic acid, and ATP production in LMCs.

224 f FGF signalling inputs results in decreased glycolysis, leading to impaired endothelial cell prolife

225 NADH towards free NADH, indicating increased glycolysis-mediated metabolic activity.

226 a vitamin B2 biosynthetic intermediate) with glycolysis metabolites such as methylglyoxal.

227 trol of several metabolic pathways including glycolysis, mitochondrial respiration and glutamine meta

228 AD, and that therapies designed at targeting glycolysis must consider both dehydrogenases.

229 rts to block the oncogenic effect of aerobic glycolysis must target reactions upstream of PKM.

230 The elevated glycolysis observed in hPSCs requires elevated MYC/MYCN

231 haracterized by abnormal growth and enhanced glycolysis of pulmonary artery endothelial cells.

232 Oxidative phosphorylation, fueled by either glycolysis or endogenously released monocarboxylates, ca

233 ippocampal neurons, ATP production by either glycolysis or oxidative phosphorylation alone sustained

234 cells seem to display heterogeneity in using glycolysis or oxidative phosphorylation as an energy sou

235 Either glycolysis or oxidative phosphorylation can fuel low-fre

236 In the glycolysis pathway, triosephosphate isomerase was up-reg

237 ion, oxidative phosphorylation (OXPHOS), and glycolysis pathways in T cells were decreased as well.

238 d enriched by HBc in the nucleus to regulate glycolysis pathways.

239 of polar metabolites revealed a reduction in glycolysis, pentose phosphate pathway, polyamines and nu

240 ch from oxidative phosphorylation to aerobic glycolysis plus glutaminolysis, markedly increasing gluc

241 tissues-namely, the rate-limiting enzyme of glycolysis pyruvate kinase (PKM), which plays a critical

242 ewal medium, younger NPCs displayed a higher glycolysis rate than older NPCs.

243 in the cytosol during GIIS that favors high glycolysis rates.

244 ly derive their cellular energy from aerobic glycolysis rather than oxidative phosphorylation even in

245 (HSCs) produce most cellular energy through glycolysis rather than through mitochondrial respiration

246 Inhibition of glycolysis reduced inflammation suggesting a causal rela

247 se carbons to biosynthetic pathways early in glycolysis reduces the carbon supply to LDH.

248 Transcriptomic analyses showed that glycolysis regulates the expression of key genes involve

249 Thus, GCK-dependent glycolysis regulates Treg cell migration.

250 rotein lipids, fatty acids, amino acids, and glycolysis-related metabolites, reflect the presence of

251 es and in turn switches glucose flux towards glycolysis relative to the pentose phosphate pathway (PP

252 We show that a critical reliance on glycolysis renders lung SqCC vulnerable to glycolytic in

253 Attenuation of glycolysis rescued the mutant phenotype of premature car

254 al regulators for flavonoid biosynthesis and glycolysis, respectively.

255 ut not local monocarboxylates or by neuronal glycolysis.SIGNIFICANCE STATEMENT Neuronal energy levels

256 ux supporting self-renewal and inhibition of glycolysis stimulating differentiation.

257 Aerobic glycolysis supports proliferation through unresolved mec

258 took up less glucose and had lower levels of glycolysis than those of wild-type controls.

259 Hyperglycemia augments a branch pathway in glycolysis, the hexosamine biosynthetic pathway (HBP), t

260 d that the direction of glucose flux between glycolysis, the pentose phosphate pathway, and serine bi

261 ence of the sugar phosphates that constitute glycolysis, the pentose phosphate pathway, and the RNA a

262 axis regulates cell growth, metastasis, and glycolysis through regulation of hexokinase 2 (HK2).

263 inhibition of cell migration, invasion, and glycolysis through suppression of microRNA (miR)-455-3p.

264 ding metabolic tumor volume and total lesion glycolysis (TLG) with different thresholds, as well as b

265 etabolic tumor volume (MTV) and total lesion glycolysis (TLG), would more accurately risk-stratify pa

266 cted (SUL) SULpeak, SULmax, and total lesion glycolysis (TLG).

267 metabolic conditions established by aerobic glycolysis to both synthesize and accumulate high concen

268 The molecular mechanisms that couple glycolysis to cancer drug resistance remain unclear.

269 In HF, Astragaloside IV switched glycolysis to fatty acid beta-oxidation, as confirmed by

270 ted receptor signaling-dependent switch from glycolysis to fatty acid oxidation.

271 glucose can be catabolized anaerobically via glycolysis to lactate, which is itself also a potential

272 e metabolism in hypoxic cells from anaerobic glycolysis to oxidative phosphorylation (OXPHOS).

273 accumulated in hypoxic regions and activates glycolysis to promote stem-like traits.

274 Cancer cells actively promote aerobic glycolysis to sustain their metabolic requirements throu

275 dynamically expends glucose through enhanced glycolysis, tricarboxylic acid metabolism and pyruvate d

276 type, that is shifted MuSC metabolism toward glycolysis triggering their return to quiescence, while

277 Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal (MG) and ad

278 bolic adaptations of lipogenesis and aerobic glycolysis under the control of Akt2 activity, but the r

279 and a reduced capacity of T cells to engage glycolysis upon TCR stimulation.

280 (13)C]-Glyc) as a novel probe for evaluating glycolysis using hyperpolarized (13)C MRS.

281 nificant shift of metabolic activity towards glycolysis using potassium cyanide, and oxidative phosph

282 s master transcriptional regulators of yeast glycolysis via directly binding and activating genes enc

283 le-rat tissues avoids feedback inhibition of glycolysis via phosphofructokinase, supporting viability

284 ammalian embryos transiently exhibit aerobic glycolysis (Warburg effect), a metabolic adaptation also

285 Glycolysis was higher in explants incubated in 25 mM glu

286 In a murine model of allergic asthma, glycolysis was induced in the lungs in an IL-1-dependent

287 We show that glycolysis was instrumental for their migration and was

288 Enhanced glycolysis was required for IL-1beta- or IL-1alpha-media

289 either ambient monocarboxylates or neuronal glycolysis was sufficient to supply requisite substrate.

290 okinase-2, which catalyzes the first step of glycolysis, was significantly lower expressed in PET fal

291 RC1 activation, macrophage proliferation and glycolysis were identified as hallmarks that correlated

292 etabolic tumor volume (MTV) and total lesion glycolysis were measured at baseline, after BV, and afte

293 me quiescent cells to reenter growth through glycolysis when nutrients are limited.

294 levels due to diminished glucose uptake and glycolysis which was rescued by Vitamin E through the ac

295 T cells have an impaired metabolic switch to glycolysis, which can be restored by IL-2.

296 itophagy promotes a metabolic switch towards glycolysis, which in turn contributes to cellular differ

297 factor-1 (HIF-1)-dependent endothelial cell glycolysis, which is crucial for pathological angiogenes

298 Both showed typical features of anaerobic glycolysis, which were paralleled by increased pyruvate

299 olic reprogramming via CDK4 toward increased glycolysis while simultaneously inhibiting NF-kappaB sig

300 rowth factor signaling was found to regulate glycolysis, with antagonism of this pathway resulting in