ライフサイエンスコーパス: glycopeptide

1 forms were detected on the Asn144-containing glycopeptide.

2 nt methods for enrichment of N- and O-linked glycopeptides.

3 drous hydrazine to cleave the N-glycans from glycopeptides.

4 was also accomplished to yield bivalent M6P-glycopeptides.

5 ycosylation site and the structure of intact glycopeptides.

6 type improved the identification of N-linked glycopeptides.

7 proteins and enrichment for glycoproteins or glycopeptides.

8 dem mass spectrometry data for assignment of glycopeptides.

9 acid linkage isomers on both N- and O-linked glycopeptides.

10 yield and identification of N- and O-linked glycopeptides.

11 pecific MALDI-TOF-MS analysis of tryptic IgG glycopeptides.

12 n of the common trimannosyl core of N-linked glycopeptides.

13 used for the structural characterization of glycopeptides.

14 d (ii) mass-independent assignment of intact glycopeptides.

15 c fragmentation of differentially sialylated glycopeptides.

16 et for antibiotics, such as beta-lactams and glycopeptides.

17 engine that interprets ETD data of N-linked glycopeptides.

18 aches in current LC-MS(2) analysis of intact glycopeptides.

19 mmonly used to enrich intact N- and O-linked glycopeptides.

20 us differentiation of glycopeptides from non-glycopeptides.

21 utomated LC/MS(E) protocol to identify the O-glycopeptides.

22 nd tetra-antennary N-glycans in the forms of glycopeptides.

23 ic peptides, hydrophilic di-/tripeptides and glycopeptides.

24 the analysis of sialyl oligosaccharides and glycopeptides.

25 also improve the characterization of intact glycopeptides.

26 ephalosporins, macrolides and ketolides, and glycopeptides.

27 y facilitates the analysis of acidic and hMW glycopeptides.

28 hromatographic resolution for acidic and hMW glycopeptides.

29 guish between the spectra of N- and O-linked glycopeptides.

30 build a spectral database of N- and O-linked glycopeptides.

31 Simultaneously with these N-glycopeptides, 53 compositional glycoforms of the hinge

32 As many as 236 N-linked glycopeptides (80%) were uniquely identified by one of t

33 To search the HCD-MS data for glycopeptides, a novel spectral-aligning strategy was de

34 f islets with synthetic AFP analog antiaging glycopeptide (AAGP) would enhance posttransplant engraft

35 68 (57%) spectra were assigned to 460 unique glycopeptides accommodating 19 N-linked and one O-linked

36 In particular, isobaric tag labeled glycopeptides after C18 desalting could be readily enric

37 Fmoc chemistry solid phase synthesis of the glycopeptide-(alpha) thioester building block.

38 nalysis by integrating glycan sequencing and glycopeptide analysis in a single experiment.

39 niversal workflow for site-specific N- and O-glycopeptide analysis of Pronase treated glycoproteins w

40 A common approach to calculate FDRs for glycopeptide analysis, adopted from the target-decoy str

41 ation with a high-fidelity profiling method, glycopeptide analysis, an unprecedented level of molecul

42 of glycoproteins for site-specific N- and O-glycopeptide analysis, resulting in a good glycopeptide

43 lectrophoresis (CE)-ESI-MS was evaluated for glycopeptide analysis.

44 n contained within for simultaneous N- and O-glycopeptide analysis.

45 A ligand-receptor interaction between a glycopeptide and a phosphopeptide produces sPGPs that fo

46 fference between the precursor ion of intact glycopeptide and the glycosite-containing peptide to a g

47 Combinations of glycopeptides and beta-lactams exert synergistic antibac

48 hed for randomized clinical trials comparing glycopeptides and beta-lactams for prophylaxis in adults

49 tion cephalosporins and any potential use of glycopeptides and carbapenems need to be addressed urgen

50 ilitated the selective characterization of O-glycopeptides and enabled the O-glycans to be identified

51 d by the presence of glycans on their intact glycopeptides and further confirmed by specific inhibiti

52 ing approach to the synthesis of homogeneous glycopeptides and glycoproteins highly demanded for func

53 on for the production of biologically active glycopeptides and glycoproteins, including therapeutic m

54 could fucosylate a wide variety of complex N-glycopeptides and intact glycoproteins by using alpha-fu

55 -MS system for analysis of released glycans, glycopeptides and monosaccharides.

56 e variety of homogeneous, core-fucosylated N-glycopeptides and N-glycoproteins that are hitherto diff

57 evidence that MRSA is becoming resistant to glycopeptides and newer therapies raises concern about t

58 We structurally assigned 32 N-glycopeptides and over 500 intact and fully elaborated O

59 his strategy depends on the observation that glycopeptides and the corresponding deglycosylated pepti

60 and universal tool through permethylation of glycopeptides and their tandem mass spectrometric analys

61 intensity of oxonium ions in the spectra of glycopeptides and utilized this information to improve t

62 research articles: 15 on beta-lactams, 10 on glycopeptides, and 12 on other antibacterial agents.

63 of complex RiPPs, including lanthipeptides, glycopeptides, and azole-containing peptides.

64 ated SCARs were able to tolerate quinolones, glycopeptides, and carbapenems.

65 mprise free oligosaccharides, glycoproteins, glycopeptides, and glycolipids.

66 ivity toward an array of selected N-glycans, glycopeptides, and glycoproteins.

67 di-/tripeptides, large hydrophobic peptides, glycopeptides, and hydrophobic drug-linked peptides.

68 d constitutes a new route to access original glycopeptide- and glycolipid-type analogues possessing a

69 to protoplasts that were pretreated with the glycopeptide antibiotic phleomycin, a nonspecific DNA do

70 distinct hydroxyl groups within the complex glycopeptide antibiotic teicoplanin A2-2.

71 Vancomycin is a glycopeptide antibiotic used for the treatment of Gram-p

72 ly established dimerization of the important glycopeptide antibiotic vancomycin in four different aqu

73 Glycopeptide antibiotics (GPAs) are nonribosomal peptide

74 VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regu

75 ycin, and we show that the activity of other glycopeptide antibiotics with this feature can also be s

76 ed total syntheses of vancomycin and related glycopeptide antibiotics, their agylcons, and key analog

77 synthesis of core-fucosylated, complex CD52 glycopeptide antigen.

78 gp120 can facilitate the rational design of glycopeptide antigens for HIV vaccine development.

79 d epithelial tumour cells, tumour-associated glycopeptide antigens have been chemically synthesised a

80 erated by the immune system, these synthetic glycopeptide antigens were conjugated to immune stimulat

81 tides are analysed by LC-MS/MS, while intact glycopeptides are characterised using a dedicated MS met

82 erize acidic and high-molecular-weight (hMW) glycopeptides are still lacking.

83 These glycopeptides are therefore of great interest in HIV vac

84 While the resulting glycopeptides are very useful for tandem mass spectromet

85 The decoys, along with target glycopeptides, are scored against the ETD data, from whi

86 lidinone and called into question the use of glycopeptides as first-line therapy.

87 lective recognition of the tumour-associated glycopeptides as was shown by neutralisation and micro-a

88 d to accurately determine FDRs for automated glycopeptide assignments, we developed GlycoPep Evaluato

89 crystal structure of IGH526 Fab with this E1 glycopeptide at 1.75A resolution revealed that the antib

90 r deglycosylation of labeled peptic N-linked glycopeptides at HDX quench conditions, i.e., acidic pH

91 cterization of intact, metabolically labeled glycopeptides at the whole-proteome scale.

92 er, it is a viable alternative to deduce the glycopeptide backbone particularly in cases when the pep

93 The structural features of MUC1-like glycopeptides bearing the Tn antigen (alpha-O-GalNAc-Ser

94 omo- and heterodimers were mis-identified as glycopeptides bearing well-defined N-linked structures,

95 Intriguingly, these glycopeptides bind in a bidirectional yet conserved conf

96 rminal selectivity is presumably due to weak glycopeptide binding to the lectin domain, whose orienta

97 in future studies as potential targets in a glycopeptide biomarker panel to further improve accuracy

98 ePhe(4),Gly-ol(5)]enkephalin (DAMGO)-related glycopeptides by altering the charged residues of the am

99 of N-glycans prior to enrichment of O-linked glycopeptides by HILIC improved identification of O-link

100 Analysis of intact glycopeptides by mass spectrometry is essential to deter

101 by HILIC improved identification of O-linked glycopeptides by mass spectrometry.

102 an use these diagnostic oxonium ions to find glycopeptides, by showing that a wealth of different gly

103 The results show that IgG glycopeptides can be analyzed directly from serum (witho

104 tides, by showing that a wealth of different glycopeptides can be found in a published phosphopeptide

105 The glycan structure of intact glycopeptides can be identified from MS/MS spectra of th

106 gorithm for glycoproteomics in which complex glycopeptides can be identified in complex mixtures to a

107 The ligated glycopeptides can be smoothly deprotected by UV irradiat

108 ally applicable for the synthesis of complex glycopeptides carrying multiple different N-glycans.

109 two sets of tandem mass spectra of N-linked glycopeptides cell lines acquired from breast cancer pat

110 admissions, greater use of fluoroquinolones, glycopeptides, cephalosporins and other expensive antibi

111 n compositions directly from intact N-linked glycopeptide collision-induced-dissociation spectra.

112 method for in vitro selection of multivalent glycopeptides, combining mRNA display with incorporation

113 Glycopeptide composition and structure can be determined

114 red that: (i) solve for both N- and O-linked glycopeptide compositions, structures and glycosites in

115 ed two variant structures, revealed that the glycopeptide contained, in addition to carbohydrate moie

116 This is the first time that a glycopeptide containing aspartic acid and an O-sulfated

117 irst synthesis of a glycosaminoglycan family glycopeptide containing two different heparan sulfate ch

118 al degradation of a plant N-glycan using a N-glycopeptide containing two GlcNAcs, three mannoses, one

119 From libraries of ~10(13) glycopeptides containing multiple Man9 glycan(s), we sel

120 A total of 501 glycopeptides corresponding to 234 proteins were identif

121 Overall, 38 unique intact glycopeptides corresponding to eight glycosylation sites

122 O-glycopeptide analysis, resulting in a good glycopeptide coverage within a single sample run and, th

123 odies specific to a gluco-asparagine (N-Glc) glycopeptide, CSF114(N-Glc), were identified in sera of

124 f N-linked glycopeptide matches, because the glycopeptide data set is considerably smaller compared t

125 GPE generates decoy glycopeptides de novo for every target glycopeptide, in

126 Glycopeptide dendrimers with high affinity to the lectin

127 erogeneous physicochemical properties of the glycopeptides depending on the peptide sequence as well

128 HLA class I presentation of O- and N-linked glycopeptides derived from membrane proteins.

129 Label-free LC-MS quantification of glycopeptides derived from these purified glycoproteins

130 rent enzymatic digestions were performed and glycopeptide detection was improved by enrichment method

131 We demonstrate herein that V1V2 glycopeptide dimers bearing Man5GlcNAc2 glycan units bin

132 mannose spacing and valency dictate whether glycopeptides engage GRFT in a face-to-face or an interm

133 y, using food-compatible processing methods, glycopeptide-enriched and beta-glucan-depleted products

134 Additionally, glycopeptide enrichment and N-glycosylation analysis ide

135 otein isolation from biofluid and subsequent glycopeptide enrichment in a single tube.

136 Most importantly, this highly efficient N-glycopeptide enrichment method enables the simultaneous

137 ty of CD4 binding site (CD4bs) and glycan or glycopeptide epitope-specific broadly neutralizing monoc

138 ictive model was evaluated in HILIC enriched glycopeptides extracted from human serum.

139 gp120, this "copy-paste" spectral pattern of glycopeptides facilitated identification of 2224 spectra

140 y deprotected single glycan chain containing glycopeptides first, followed by union of the glycan-bea

141 to either Thr-99 or Thr-101, forming a core glycopeptide for subsequent additions of in all 11 GalNA

142 ins and cephalosporins for SJS/TEN and AGEP; glycopeptides for DRESS.

143 efficient and specific enrichment of intact glycopeptides for identification and quantitation.

144 n, were used separately to generate suitable glycopeptides for online LC tandem MS analysis.

145 ectiveness of switching from beta-lactams to glycopeptides for preoperative antibiotic prophylaxis ha

146 d as a therapeutic alternative to the use of glycopeptides for the treatment of pneumonia caused by m

147 this assay we were able to directly quantify glycopeptide formation by Actinobacillus pleuropneumonia

148 A glycoproteomics approach of the wild type glycopeptide fraction revealed Asn-732 peptide fragments

149 The final assembly of the individual glycopeptide fragments involved a stepwise native chemic

150 elucidation of the glycan structure within a glycopeptide from its collision-induced dissociation tan

151 Eight glycoforms of an O-linked glycopeptide from Nucleobindin-1 are distinguished on th

152 We identified 291 unique glycopeptides from 195 glycoproteins; the comparative st

153 s and over 500 intact and fully elaborated O-glycopeptides from 250 proteins across three human cance

154 (2) spectra in 3 min on a PC and reported 36 glycopeptides from 26 glycoproteins.

155 his framework, 103 highly confident N-linked glycopeptides from 53 sites across 33 glycoproteins were

156 d protein chips showed the ability to enrich glycopeptides from complex mixtures with subsequent MALD

157 r key areas: enrichment of glycoproteins and glycopeptides from complex mixtures, emphasizing methods

158 Tandem spectra of glycopeptides from fetuin, glycophorin A, ovalbumin and

159 Without enrichment of glycopeptides from global tryptic peptides and at a fals

160 A mixture of novel glycopeptides from glycosylation between cold water fish

161 which led to the identification of 7 tryptic glycopeptides from HRP and 16 glycopeptides from the mix

162 ubstantially unbiased enrichment of N-linked glycopeptides from human serum.

163 the characterization of glycan structures in glycopeptides from MS/MS analysis.

164 ions enabled unambiguous differentiation of glycopeptides from non-glycopeptides.

165 n of 7 tryptic glycopeptides from HRP and 16 glycopeptides from the mixture via Mascot.

166 ptidome leads to the identification of 609 N-glycopeptides from the secretome and lysates of Huh7 cel

167 e mass spectrometer to identify low abundant glycopeptides from virion-associated gp120.

168 to examine fragmentation patterns of intact glycopeptides generated from a mixture of standard glyco

169 lisional dissociation (HCD) fragmentation of glycopeptides generates mono- or disaccharide ions calle

170 rolling multivalent interactions we designed glycopeptide HMTG mimetics with systematically varied ma

171 al framework for identifying intact N-linked glycopeptides, i.e. glycopeptides with N-linked glycans

172 sis is a major bottleneck to high-throughput glycopeptide identification based on ETD data, due to th

173 Although impressive numbers of glycopeptide identification by a direct database search

174 present a mass spectrometry-based automated glycopeptide identification platform (MAGIC) to identify

175 These studies suggest that glycopeptide immunogens can be designed to stabilize the

176 t characterization of intact N- and O-linked glycopeptides in a single liquid chromatography-tandem m

177 the HCD LC-MS/MS generated spectra of intact glycopeptides in an automated and high-throughput manner

178 information to improve the identification of glycopeptides in biological samples.

179 chniques have facilitated analysis of intact glycopeptides in complex biological samples by allowing

180 lation requires the identification of intact glycopeptides in samples, including identification of th

181 leading to the presence of false glycans or glycopeptides in the sample.

182 TD) is commonly used in fragmenting N-linked glycopeptides in their mass spectral analyses to complem

183 samine, leading to the synthesis of epimeric glycopeptides in vitro.

184 decoy glycopeptides de novo for every target glycopeptide, in a 1:20 target-to-decoy ratio.

185 ence of m-NBA the charge state of sialylated glycopeptides increased and the chromatographic separati

186 all permeability and is complementary to the glycopeptide inhibition of cell wall synthesis, was foun

187 ides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9

188 omain enables free acceptor sites binding of glycopeptides into the catalytic domain.

189 AVATA3 (CLV3) gene, which encodes a secreted glycopeptide involved in the regulation of the centrally

190 Additionally, an acceptor glycopeptide is a less efficient substrate for POMGNT2 w

191 al infusion concentration of 5 mg.mL(-1) all glycopeptide is dimerized whilst at 19 microg.mL(-1) (a

192 This glycopeptide is more resistant to hydrolytic degradation

193 lycoform on the ionization properties of the glycopeptide is observed.

194 The use of vaccines based on MUC1 glycopeptides is a promising approach to treat cancer.

195 d on our discovery that the fragmentation of glycopeptides is glycan-structure dependent and glycans

196 se spectra, leading to identification of the glycopeptides, is challenging.

197 on-induced dissociation (CID) data of intact glycopeptides isolated from mouse liver tissue are prese

198 otential in achieving automation of N-linked glycopeptide isolation for high-throughput sample prepar

199 vised and an integrated workflow of N-linked glycopeptide isolation using hydrazide tips was presente

200 fore, to facilitate high throughput N-linked glycopeptide isolation, in this study, a novel hydrazide

201 nt identification of these glycoforms at the glycopeptide level by mass spectrometry (MS) requires a

202 ation profile, albeit mainly at a glycan and glycopeptide level of analysis.

203 pecific glycosylation analysis of IgG at the glycopeptide level.

204 entified for the Asn340-containing tailpiece glycopeptide, mainly of the diantennary complex type, an

205 imal in measuring the confidence of N-linked glycopeptide matches, because the glycopeptide data set

206 Peptidoglycan (PG) is an extracytoplasmic glycopeptide matrix essential for the integrity of the e

207 The trivalent glycopeptide mimetic and analogues have the potential to

208 ynthesis and binding analysis of a trivalent glycopeptide mimetic.

209 Opioid binding affinities of the O-linked glycopeptides (mono- or disaccharides) and unglycosylate

210 ides, resulting in assignment of each intact glycopeptide MS/MS spectrum to a specific glycosite-cont

211 d complex-type N-glycans in the context of N-glycopeptides, N-glycoproteins, and intact antibodies.

212 infection, is a 12-amino acid arabinosylated glycopeptide (named GrCLE1-1Hyp4,7g) with striking struc

213 The glycopeptide nanostructures amplified signalling of bone

214 We report here on supramolecular sulfated glycopeptide nanostructures, which display a trisulfated

215 exemplified by an efficient synthesis of the glycopeptide neutralizing epitope of broadly HIV-neutral

216 for Sequencing and Identification of Intact Glycopeptides", noncovalent homo- and heterodimers were

217 a strategy for the permethylation of intact glycopeptides, obtained via controlled protease digest,

218 ng many hurdles in synthesizing proteoglycan glycopeptides, one challenge is the incorporation of asp

219 For the glycoforms of a given glycopeptide or set of derivatized glycans, the slope of

220 intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides),

221 orm separation for both released glycans and glycopeptides over that reported for chromatography mode

222 s to be unfeasible in the alpha-O-GalNAc-Thr glycopeptide owing to the more limited flexibility of th

223 enzymatically removing sugars outside the N-glycopeptide pentasaccharide core with exoglycosidases.

224 hout compromising much sensitivity in intact glycopeptide positive spectrum matches.

225 The Flavourzyme-derived glycopeptides prepared at 37 degrees C (FFC37 and FFT37)

226 enzymes, allowed us to propose a model of N-glycopeptide processing by X. campestris pv. campestris.

227 Y1 fragment from the HCD spectra of N-linked glycopeptides, producing an abundant Y1-48 Da ion instea

228 f immune suppression, render these unnatural glycopeptides promising candidates for designing alterna

229 Finally, NMR analysis of flagellin glycopeptides provided complementary information.

230 Glycopeptides reduce the risk of resistant staphylococca

231 However, compared with beta-lactams, glycopeptides reduced the risk of resistant staphylococc

232 Glycopeptides related to beta-endorphin penetrate the bl

233 Detailed analysis of a LLDGSSTEIR glycopeptide released by tryptic digestion, which carrie

234 The analysis of N- and O-glycopeptides remains challenging due to the microhetero

235 effectiveness to enrich isobarically labeled glycopeptides remains unclear.

236 were assigned to 769 unique intact N-linked glycopeptides, representing 344 N-linked glycosites with

237 nomeric enterococcal VanS kinase involved in glycopeptide resistance regulation.

238 d (9 glycopeptides) or without enrichment (6 glycopeptides), respectively.

239 hms are presented for tandem mass spectra of glycopeptides resulting from collision-induced dissociat

240 examine the gas-phase structures of a set of glycopeptides resulting from proteolytic digestion of th

241 ention times: sialic acid addition increases glycopeptide retention times significantly; replacing th

242 matographic separation of neutral and acidic glycopeptides revealed a remarkable improvement.

243 We also describe the properties of glycopeptide scaffolds from the V1/V2 domain also expres

244 proach, however, important information about glycopeptide sialylation is not duly covered because of

245 re, we present the first study revealing AFP glycopeptide signatures of individual HCC patients, comp

246 ) is the method of choice in analyzing these glycopeptides since the glycan side chain remains intact

247 It allows postacquisition extraction of glycopeptide-specific fragment-ion chromatograms to be a

248 he lectin domains of GalNAc-Ts contribute to glycopeptide specificity and catalysis remains unclear.

249 origins of its unique N-terminal long-range glycopeptide specificity, which is the opposite of GalNA

250 Interpretation of intact glycopeptide spectra is crucial but challenging.

251 ng glycan oxonium ions as signature ions for glycopeptide spectra.

252 ing four human OGA structures complexed with glycopeptide substrates containing a single O-GlcNAc mod

253 of OGA in complex with each of four distinct glycopeptide substrates that contain a single O-GlcNAc m

254 -selective alteration including polyketides, glycopeptides, terpenoids, macrolides, alkaloids, carboh

255 further limits the number of possible decoy glycopeptides tested in a database search.

256 S analysis) to identify a number of putative glycopeptides that carried a variety of glycoform substi

257 al ultracentrifugation, and microcalorimetry glycopeptides that fully recapitulate the specificity an

258 al structures of complexes of GalNAc-T2 with glycopeptides that together with enhanced sampling molec

259 ed for the glycoforms of individual N-linked glycopeptides, the deglycosylated peptides, and the rele

260 This feature enables the correct glycopeptide to receive a high score while keeping score

261 n, as a bait, we narrowed a library of 10(8) glycopeptides to 86 leads that share a consensus motif,

262 y (GE-FBD) uses selection of phage-displayed glycopeptides to dock a glycan fragment at the CRD and g

263 chemical enrichment and isotopic recoding of glycopeptides to select peptides for targeted glycoprote

264 , for site-specific identification of intact glycopeptides using higher-energy collisional dissociati

265 bles rapid setup and analysis of glycans and glycopeptides using mass spectrometry.

266 eous analysis of serum-derived IgA1 N- and O-glycopeptides using matrix-assisted laser/desorption ion

267 red the enrichment of intact N- and O-linked glycopeptides using other chromatography methods and fou

268 ably distinguish between the N- and O-linked glycopeptides using the spectral features of the oxonium

269 d the use of this method to design potential glycopeptide vaccines against HIV.

270 The glycan structure of a given glycopeptide was determined by collision-induced dissoci

271 ersion of homoserine to aspartic acid in the glycopeptide was successfully accomplished by late stage

272 ive and comprehensive enrichment of N-linked glycopeptides was developed to facilitate detection of m

273 The enrichment of O-linked glycopeptides was further improved when a Retain AX cart

274 approach for measuring arginine-GlcNAcylated glycopeptides, we assessed the global profile of arginin

275 mpositional glycoforms of the hinge region O-glycopeptide were profiled in a single high resolution M

276 IgG tryptic glycopeptides were analyzed by liquid chromatography ele

277 Two series of glycopeptides were assessed for opioid receptor binding

278 Glycopeptides were assigned to proteins using RefSeq (Na

279 Glycopeptides were enriched using zwitterionic HILIC zip

280 Up to 25-fold higher sensitivities for model glycopeptides were obtained, allowing for limits of dete

281 human serum, multiple parallel isolations of glycopeptides were performed using hydrazide tips with a

282 N-linked plasma glycopeptides were quantified by solid-phase extraction

283 Spectra of intact glycopeptides were selected by using glycan oxonium ions

284 Of these, 66 glycopeptides were unique to the survivor group and corr

285 proteoglycan core proteins by identifying CS-glycopeptides with a combination of biochemical enrichme

286 largely overcome this problem by generating glycopeptides with a small peptide portion.

287 Moreover, glycopeptides with an identical peptide backbone show ne

288 The ionization properties of the glycopeptides with different classes of glycan structura

289 wing the users to generate spectra of intact glycopeptides with glycans attached to each specific gly

290 s, methodologies to synthesize this class of glycopeptides with homogeneous glycans are not well deve

291 ntifying intact N-linked glycopeptides, i.e. glycopeptides with N-linked glycans attached to their gl

292 Using synthetic glycopeptides with O-GalNAc (the Tn antigen) or O-GlcNAc

293 emonstrated that the method is selective for glycopeptides with O-GalNAc and can distinguish between

294 undecaprenol diphosphate-linked glycans and glycopeptides with site-specific introduction of azide f

295 y the MS(3) spectra of the oligomannosylated glycopeptides with the same Y1 ion.

296 thod and confidence in the identification of glycopeptides with the Tn antigen by mass spectrometry.

297 ity to base treatment and the instability of glycopeptides with two glycan chains towards catalytic h

298 assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total gl

299 ic protein glycosylation information, intact glycopeptides, with the glycan attached to the peptide s

300 ol that helps to measure FDRs in identifying glycopeptides without using a decoy database.