ライフサイエンスコーパス: glycosidase

1 yclitol derivatives was tested against alpha-glycosidase.

2 howed significant inhibition of at least one glycosidase.

3 frame confirmed that this gene encodes an O-glycosidase.

4 enetic complementation and the addition of O-glycosidase.

5 e peptide moieties are released by peptide-N-glycosidase.

6 probed by various perturbants, proteases, or glycosidase.

7 amily, DUF2233 functions as a phosphodiester glycosidase.

8 enoic and benzenoic aglycones than the yeast glycosidases.

9 ure-specific catabolism based on a number of glycosidases.

10 se to recognize and modify certain lysosomal glycosidases.

11 as their specific inhibitory behavior toward glycosidases.

12 e-suppression protein that has homology with glycosidases.

13 ere assayed as inhibitors against a panel of glycosidases.

14 eutic agents due to their ability to inhibit glycosidases.

15 man red blood cell (RBC) glycoproteins using glycosidases.

16 njugates could release NO in the presence of glycosidases.

17 n reaction mechanism for both alpha and beta-glycosidases.

18 s their immunogenicity and susceptibility to glycosidases.

19 st glycans as they are modified by bacterial glycosidases.

20 e as acid/base catalyst, which is unique for glycosidases.

21 to the mechanisms accepted for 'retaining' O-glycosidases.

22 oped a rapid electrochemical assay to detect glycosidases.

23 c group that could be easily bioactivated by glycosidases.

24 proteins, including glycosyltransferases and glycosidases.

25 ediated by the consecutive action of several glycosidases.

26 rides using two glycosidases, multisubstrate glycosidase A (MsgA) and neuraminidase (NanA).

27 These results suggest that glycosidases acting on nonreducing ends digest large amo

28 elivery of nitric oxide (NO), a new class of glycosidase activated NO donors has been developed.

29 etary compounds and xenobiotics, while other glycosidase activities are involved in the conversion of

30 rtantly, the increased lipase, protease, and glycosidase activities associated with periodontitis gen

31 These new substrates can be used to assay glycosidase activities in a wide pH range (4-11) and wit

32 The newly discovered DNA-O-glycosidase activities of both enzymes compare favorably

33 iluminescence (ECL)-based detection of RNA N-glycosidase activities of toxins.

34 Other faecal glycosidase activities showed little or no change over a

35 to tumor cells with cell surface or secreted glycosidase activities.

36 Nitrogen addition significantly increased glycosidase activity (GA) by 13.0%, alpha-1,4-glucosidas

37 Manipulation of beta-glycosidase activity and isoflavone composition can be u

38 mide gel electrophoresis and showed strong N-glycosidase activity as manifested by the depurination o

39 ha-synuclein, suggesting that increasing the glycosidase activity can modulate alpha-synuclein proces

40 y of enzymes long believed to possess rRNA N-glycosidase activity directed solely at the universally

41 nant gelonin-LMWP chimera (rG-L) possessed N-glycosidase activity equivalent to that of unmodified re

42 ectrochemiluminescence-based assay for RNA N-glycosidase activity has been modified to permit its use

43 we use this designed switch to modulate beta-glycosidase activity in living cells using indole.

44 Mutational loss of this glycosidase activity in Y. pestis may have contributed t

45 Analysis of glycosidase activity in zebrafish and medaka eggs reveal

46 ble that these are products of an additional glycosidase activity of lyase III, although other mechan

47 e mutant, indicating that it is due to the N-glycosidase activity of the protein.

48 ontact with residues involved in RTA's RNA N-glycosidase activity or induced notable allosteric chang

49 beta-Glycosidase activity was quantified using p-nitrophenol-

50 Almond beta-glycosidase activity was significantly (p<0.001) reduced

51 SIM beta-glycosidase activity, however, increased, with steaming

52 ricin A chain, which contains the toxin's N-glycosidase activity.

53 ycosidase evolved its highly efficient trans-glycosidase activity.

54 The conformational analysis of glycosidases affords a route to their specific inhibitio

55 he intracellular activities of the lysosomal glycosidases alpha-galactosidase, alpha-mannosidase and

56 s (conduramines) were tested against several glycosidases (alpha- and beta-glucosidase, alpha- and be

57 to a glycosynthase derived from a retaining glycosidase, an important class of enzymes for carbohydr

58 their efficacy as enzyme inhibitors of beta-glycosidase and against several solid-tumor cell lines f

59 Analysis with glycosidase and cell surface biotinylation indicates tha

60 ximide led to intracellular depletion of the glycosidase and concomitant ablation of asparagine-linke

61 Besides glycosidase and glycanase activities, five new transglyc

62 components are hydrolysed by numerous plant glycosidase and glycanase activities.

63 AlnA and AlnB, members of the pseudouridine glycosidase and haloacid dehalogenase enzyme families, r

64 ng a sensitive approach that combines in-gel glycosidase and protease digestions, permethylation of r

65 esign of synthetic agents that mimic natural glycosidases and address current problems for biological

66 Treatment with various glycosidases and binding to soybean agglutinin indicated

67 Cells treated with glycosidases and coinjected with the peptide formed live

68 dification of the initial oligosaccharide by glycosidases and glycosyltransferases during the glycopr

69 consecutive actions of functionally distinct glycosidases and glycosyltransferases.

70 ra-Golgi localization of sequentially acting glycosidases and glycosyltransferases.

71 ose (sugar) used as a potential inhibitor of glycosidases and low-calorie carbohydrate sweeteners.

72 Several hydrolytic activities, including glycosidases and proteases, have been previously correla

73 lin A (SIgA) as a substrate of BV-associated glycosidases and proteases.

74 leoside analogues as potential inhibitors of glycosidases and purine nucleoside phosphorylase (PNP) h

75 of the properties and mechanisms of GH1 beta-glycosidases and related enzymes that modulate their act

76 re due to a deficiency of certain hydrolases/glycosidases and subsequent accumulation of nonhydrolyza

77 alts, and other ingredients (e.g., PNGase F, glycosidase, and transferase reaction mixtures).

78 rts are also potent inhibitors of intestinal glycosidases, and because of this characteristic, we reg

79 Cell surface biotinylation, sensitivity to glycosidases, and fluorescence microscopy analyses sugge

80 g machineries, such as glycosyltransferases, glycosidases, and nucleotide sugar transporters, but als

81 ese hydrolases comprise an array of lipases, glycosidases, and proteases and thus, they have the pote

82 ested against several commercially available glycosidases, and some of them showed good and selective

83 osed-system assay and uses a dUTP/uracil DNA glycosidase anti-PCR contamination control.

84 nts, Glycoside Hydrolase (GH) Family 1 beta -glycosidases are believed to play important roles in man

85 Glycosidases are essential enzymes that cleave glycoside

86 e site glutamate residues found in retaining glycosidases are present in hydroxyisourate hydrolase as

87 r glycosylation-the glycosyltransferases and glycosidases-are essential in the development and physio

88 es for their kinetic competency with a given glycosidase as a step to name these enzymes not just for

89 tracts containing recombinant, overexpressed glycosidase as the easily accessible enzyme source.

90 g flavin mononucleotide-binding proteins and glycosidases as examples, we show how the evolutionary p

91 pment of substrate probes for monitoring exo-glycosidases, as well as a range of other enzymes having

92 Common glycosidase assays rely on the hydrolysis of non-natural

93 Additional glycosidase assays were performed to identify potential

94 s/group, 5 samples/pool) and complemented by glycosidase assisted analysis using sialidase and endogl

95 Glycosidase assisted LC-MS-MRM analysis of individual pa

96 the synthesis of fluorogenic substrates for glycosidases based on a sulfonated 7-hydroxycoumarin sca

97 conju-gates as well as for identifying other glycosidases belonging to the new GH98 family.

98 tallographic symmetry) of the 6-phospho-beta-glycosidase, BglT, from T.maritima in native and complex

99 Using a specific glycosidase, both phages penetrate the capsule and infec

100 logous to family 1 glycosyl hydrolases (beta-glycosidases), but the predicted AtSFR2 protein is diver

101 conclude that certain proteins annotated as glycosidases can function as transglycosidases.

102 catalytic function of this enzyme as a beta-glycosidase capable of catalyzing the hydrolysis of gluc

103 use of food-grade commercial plant cell-wall glycosidases (Celluclast/Novozyme plus Viscozyme) allows

104 ecificity was studied on a panel of relevant glycosidases (cellulases and xylanases) in microtiter pl

105 r and high density of N-linked glycans, with glycosidase digestion abrogating 2G12 cross-reactivity.

106 Glycosidase digestion confirmed the identity of the nonr

107 Glycosidase digestion of the 2 m eluate yielded protein

108 Glycosidase digestion revealed that inhibition of DGK re

109 Glycosidase digestion showed that rat and human corin pr

110 y activated CTL clones combined with various glycosidase digestions and GC-MS linkage analyses.

111 released from DSP following N- and O-linked glycosidase digestions, but these digestions had little

112 nt of myotubes with neuraminidase and endo-O-glycosidase diminished alpha-dystroglycan binding to pea

113 cteriophages can digest these capsules using glycosidases displayed on the phage particle.

114 to arginine should destabilize the putative glycosidase domain (KL1) of KL, thereby attenuating prod

115 NET37 mutated at a conserved residue in the glycosidase domain and found that this predicted catalyt

116 taKlotho, a membrane protein with 2 putative glycosidase domains, have increased Cyp7a1 mRNA levels a

117 rovide novel insight into the role of acidic glycosidases during yolk utilization and the evolution o

118 In addition to the K1-specific glycosidase, each K1-5 particle carries a second enzyme

119 ia, the simultaneous characterization of all glycosidases employed by bacteria for the catabolism of

120 porters were often coregulated with adjacent glycosidase-encoding genes.

121 d between a constitutive promoter and a beta-glycosidase-encoding reporter gene (TK1761).

122 We used the glycosidase endoglycosidase H to determine that this dif

123 ide evidence that P2X(7) is sensitive to the glycosidases EndoH and PNGase F and that the human recep

124 We present two examples, W33G in a beta-glycosidase enzyme (beta-gly) and W492G in a beta-glucur

125 on the basis of the partition coefficient of glycosidase enzyme activity (Kca).

126 l five iminosugars were studied with various glycosidase enzymes and compared with natural d-gluco-1-

127 Thus, combinations of acid hydrolysis and glycosidase enzymes in almond and flax seed were most ef

128 , we digested recombinant gp120 with various glycosidase enzymes of known specificities and showed th

129 In vitro screening against several glycosidase enzymes showed highly specific inhibition of

130 ere found to be potent inhibitors of various glycosidase enzymes with Ki and IC50 values in the micro

131 ical practice has been the lack of efficient glycosidase enzymes.

132 and subsequently were digested with specific glycosidase enzymes.

133 on glass slides were incubated with selected glycosidase enzymes.

134 e is strikingly similar to that of retaining glycosidases, even though it catalyzes hydrolysis of an

135 herent dynamic framework to understand how a glycosidase evolved its highly efficient trans-glycosida

136 The collective action of BV-associated glycosidases exposes underlying mannose residues of SIgA

137 ized by the classical glycosidases peptide-N-glycosidase F (PNGase F) and endoglycosidase H (Endo H).

138 in electrophoretic mobility after peptide-N-glycosidase F (PNGase F) digestion suggest that both PED

139 nline enzyme reactor incorporating peptide-N-glycosidase F (PNGase F) on a monolithic polymer support

140 Deglycosylation with protein-N-glycosidase F (PNGase F) reduced the size of both lung a

141 ies, dual digestion by trypsin and peptide-N-glycosidase F (PNGase F), and analysis by LC-MS/MS.

142 -linked glycosylated peptides via peptide- N-glycosidase F (PNGase F).

143 ed with GPVI, deglycosylation with peptide-N-glycosidase F (PNGase F; specific for complex N-linked g

144 A deglycosylation step using Peptide-N-Glycosidase F (PNGaseF) has been introduced in a standar

145 Application of an endoglycosidase, peptide N-glycosidase F (PNGaseF), directly on tissues followed by

146 Moreover, treatment with peptide N-glycosidase F abrogated F240 neutralization, in an isola

147 munoprecipitated TPP I proenzyme with both N-glycosidase F and endoglycosidase H as well as treatment

148 ith Flavobacterium meningosepticum peptide N-glycosidase F and trypsin, with matrix-assisted laser de

149 P-2 is resistant to digestion with peptide N-glycosidase F but is sensitive to release under alkaline

150 Peptide-N-glycosidase F digestion of solubilized hKOR or incubatio

151 etreatment of the lactoferrin with peptide N-glycosidase F or addition of heparin or chondroitin sulf

152 ted species and was converted to 27 kDa by N-glycosidase F or tunicamycin treatments.

153 Treatment with peptide-N-glycosidase F reduced the size of the mammalian cell- an

154 e glycosylated, and treatment with peptide N-glycosidase F reduces the apparent molecular mass on SDS

155 Treatment of heart lysates with peptide-N-glycosidase F revealed that while giant obscurin-B local

156 beta-N-acetylglucosaminidase H and peptide:N-glycosidase F sensitivity assays on CDKAL1 constructs ca

157 t of kidney membrane proteins with peptide N-glycosidase F showed that GLUT9 and GLUT9DeltaN are expr

158 Etanercept was first treated with peptide N-glycosidase F to release the N-glycans.

159 bound fractions, and treated with peptide: N-glycosidase F to remove N-linked glycans.

160 cosylation was responsible because peptide N-glycosidase F treatment of isolated 170-kDa EGFR yielded

161 oproteins and molecular mass after peptide-N-glycosidase F treatment was 38 and 45 kDa, respectively.

162 N-linked carbohydrate was removed by using N-glycosidase F was markedly less effective in protecting

163 uronic acid as well as proteoglycan N-linked glycosidase F(PNGaseF)- and sialidase A-treated human er

164 tein-tagged mCLCA6 with PNGase F (peptide: N-glycosidase F) to remove N-linked glycosyl groups shows

165 Peptide N-glycosidase F, but not endoglycosidase H, digestion conv

166 y 120 kDa following treatment with peptide:N-glycosidase F, consistent with N-glycosylation being the

167 Digestion with N-glycosidase F, endoglycosidase H and lectin blotting did

168 y released from glycoproteins with peptide N-glycosidase F, followed by purification with graphitized

169 e cultured medium, and upon treatment with N-glycosidase F, the molecular mass was lowered by approxi

170 mass spectrometry on purified and peptide N-glycosidase F-deglycosylated CD36 and also by comparing

171 ately 160 kDa after treatment with peptide N-glycosidase F.

172 more rapid migration after treatment with N-glycosidase F.

173 pproaches, including use of either peptide:N-glycosidases F and A (PNGase F and A) or anhydrous hydra

174 g sequential endoglycosidase H and peptide:N-glycosidase-F digestions.

175 of the full-length homotrimer with peptide N-glycosidase-F under native conditions abolished recognit

176 NET37, a member of glycosidase family 31, is highly expressed in mouse skel

177 select agent toxin and a member of the RNA N-glycosidase family of medically important plant and bact

178 h trans and then medial glycosyltransferases/glycosidases found in the scattered, nascent Golgi.

179 mparable to profiling by PNGase F (peptide N-glycosidase from Flavobacterium meningosepticum) digesti

180 owed by an enzymatic treatment with the beta-glycosidase from Periplaneta americana allowed the effic

181 This study investigated the role of beta-glycosidase from processed soy-ingredient mixture (SIM)

182 able insight into the mechanism of a novel N-glycosidase from the structural point of view, which in

183 Removal of the oligosaccharides by glycosidase from wild-type carboxylase or by elimination

184 er homology to the sequences of several beta-glycosidases from thermophilic archea and bacteria.

185 iously unreported sites that are crucial for glycosidase function.

186 Glycosidase gel shift analysis suggested that K(v)2.1, K

187 ed unusually frequent mutation of the beta-D-glycosidase gene (lacS) of a shuttle plasmid (pJlacS) pr

188 of the regulation of expression of the beta-glycosidase gene (lacS) were conducted.

189 Here we report two bacterial glycosidase gene families that provide enzymes capable o

190 on OC cell lines targeted by mAb-A4, we used glycosidases, glycan microarray, siRNA, and advanced hig

191 stence of monofunctional transpeptidases and glycosidases (glycoside hydrolases), trimeric peptide cr

192 The presence of glycosidases have been widely used to detect pathogens,

193 By protease mapping we show that its glycosidase homology domain is located in the lumen of t

194 elopment of FRET-quenched substrates for exo-glycosidases, however, has been hindered by their constr

195 ot disruptable by a variety of exo- and endo-glycosidases, implying recognition of a non-glycan epito

196 761, a gene that encodes a nonessential beta-glycosidase in Thermococcus kodakaraensis.

197 tudy investigates the collateral activity of glycosidases in commercial pectinase preparations, and t

198 l gut and become activated by bacterial beta-glycosidases in the distal gut.

199 lases and recently discovered apoplastic exo-glycosidases in the hydrolytic modification of matrix xy

200 chemical properties, and function of several glycosidases in zebrafish eggs, embryos, and adult tissu

201 ween hydroxyisourate hydrolase and retaining glycosidases; in particular, the conserved active site g

202 f their binding affinities toward a panel of glycosidases including the Jack Bean alpha-mannosidase (

203 ymes, such as lipoxygenases, peroxidases and glycosidases, including myrosinase in broccoli, is key t

204 Endogenous glycosidases, including neuraminidase 1 (Neu1), neuramin

205 e detected with other adenine-specific RNA N-glycosidases, including Ricinus communis agglutinin (RCA

206 ced to lower Mr bands by neuraminidase and O-glycosidase, indicating that the hKOR contains O-linked

207 ynthesized molecules have been evaluated for glycosidase inhibition against 6 commercially available

208 Glycosidase inhibition and lectin deficiencies increased

209 A definitive side-by-side comparison of the glycosidase inhibition of a panel of 13 glycosidases sho

210 , and some of them showed good and selective glycosidase inhibition.

211 iminosugars have been recently explored for glycosidase inhibition.

212 the structural features and their effect on glycosidase inhibitions.

213 active approach to the rapid optimization of glycosidase inhibitor potency and pharmacokinetic behavi

214 ion to the concise preparation of the potent glycosidase inhibitor, (-)-swainsonine.

215 rry 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency in the su

216 pseudoviruses produced in the presence of a glycosidase inhibitor, kifunensine.

217 labeled thiosugar was prepared as a putative glycosidase inhibitor.

218 its d-enantiomer, l-NBDNJ does not act as a glycosidase inhibitor.

219 lipids, and biguanides, sulfonylureas, alpha-glycosidase inhibitors [AGIs], and insulin adjusted for

220 The importance of glycosidase inhibitors and especially the bicyclic molec

221 -throughput assays for identifying retaining glycosidase inhibitors by FluoPol-ABPP on cell extracts

222 itive patterns of inhibition for a number of glycosidase inhibitors.

223 al processing of N-glycans was blocked using glycosidase inhibitors.

224 ased iminocyclitols are a promising class of glycosidase inhibitors.

225 yl substituted aminocyclitols were tested as glycosidase inhibitors.

226 of pseudoviruses in the presence of various glycosidase inhibitors; and (iii) the growth of pseudovi

227 xhibiting outstanding biological activity as glycosidases inhibitors.

228 The glycosidase inhibitory activities of all five iminosugar

229 addition of various glycosyltransferases and glycosidases into nascent, golgin-enriched structures af

230 The low basal concentration of the glycosidase is believed to coordinate the glycan cleavag

231 pecific enzymes like proteases, esterases or glycosidases is often higher in tumor cells than in norm

232 of five distinct protein domains, including glycosidase, leucine-rich repeat, hybrid Ig, carbohydrat

233 grade glycans into monosaccharides using two glycosidases, multisubstrate glycosidase A (MsgA) and ne

234 the long held view that potent inhibitors of glycosidases must mimic an oxacarbenium ion like transit

235 The ability of the O-glycosidase mutant to cleave this glycan structure was r

236 fin granule membranes in the presence of the glycosidase N-glycanase shifted the apparent molecular w

237 borative activities of glycosyltransferases, glycosidases, nucleotide-sugar transporters, sulfotransf

238 are efficiently turned over by the human exo-glycosidase O-GlcNAcase (OGA).

239 ce protein with sequence similarity to the O-glycosidase of Bifidobacterium longum.

240 in is divergent from all other family 1 beta-glycosidases of Arabidopsis, showing closer homology to

241 dies, respectively, as they do not carry out glycosidase or glycosyl transferase reactions, and they

242 l applications, but the use of either enzyme glycosidases or small-molecule catalysts in biological s

243 d insensitive to physiological temperatures, glycosidases, or host cell degradation.

244 ly N-glycans not recognized by the classical glycosidases peptide-N-glycosidase F (PNGase F) and endo

245 After incubation with beta-glycosidase, percentage of aglycone (total aglycone/tota

246 processing alpha1,2-mannosidases (family 47 glycosidases) play critical roles in the maturation of A

247 Moreover, O-glycosidase-pretreated mucin did not block gene transfer

248 reciated that some bacterial species express glycosidases, previous studies have not considered wheth

249 Glycosidases produced by some normal colonic bacteria an

250 Remarkably, sequential glycosidase-protease digests led to a complete or near-c

251 Using glycosidases, proteases, Western blotting, confocal micr

252 ding cleft topologies of the other family 47 glycosidases provides a framework for understanding the

253 ugh the biological significance of the DNA-O-glycosidase reactions is not known, the evolution of new

254 of electrochemically inactive substrates to glycosidases releases glucose, which can be measured eas

255 idues, and binding to gp120 was abrogated by glycosidase removal of high-mannose glycans and terminal

256 and celery were used to test the effects of glycosidase-rich foods and thermal processing on the sta

257 ur method to map the activity of millions of glycosidase sequence variants.

258 the glycosidase inhibition of a panel of 13 glycosidases showed that 8 of the 10 stereoisomers showe

259 Knowledge of lectin and glycosidase specificities is fundamental to the study of

260 determination and description of lectin and glycosidase specificities.

261 The anti-aging hormone klotho and other glycosidases stimulate TRPV5-dependent Ca(2+) uptake.

262 ce that S. pneumoniae expresses a secreted O-glycosidase that cleaves galactose beta1-3 N-acetylgalac

263 some-inactivating protein (RIP) and an RNA N-glycosidase that removes specific purine residues from t

264 active HA degradation by treatment with beta-glycosidases that act at the nonreducing end.

265 Using specific glycosidases that convert A and B glycans to the underly

266 osome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific adenine residue

267 proteins (RIPs) from angiosperms are rRNA N-glycosidases that have been proposed as defence proteins

268 S. pneumoniae is known to encode a number of glycosidases that may modify these glycoconjugates in vi

269 Ribosome-inactivating proteins (RIPs) are N-glycosidases that remove a specific adenine from the sar

270 Ribosome-inactivating proteins are N-glycosidases that remove a specific adenine from the sar

271 code enzymes termed glycosyltransferases and glycosidases that reside in the Golgi apparatus where th

272 to the upregulation of CsBGLU18 (an ABA beta-glycosidase) that cleaves ABAGE.

273 Glycosynthases, which are mutant glycosidases, that can readily form glycosidic linkages

274 While Rpf proteins are clearly peptidoglycan glycosidases, the mechanism and role of Rpf in mediating

275 u; however, in contrast to proteases and exo-glycosidases, there are no simple guidelines for the des

276 an sequentially be decaged by an appropriate glycosidase to liberate a terminal beta-GlcNAc moiety, w

277 type Kv1.2 channels on the cell surface with glycosidase to remove sialic acids also results in the f

278 odel glycoconjugate demonstrated that this O-glycosidase, together with the neuraminidase NanA, is re

279 differentiated from a larger selection of N-glycosidase toxins than was previously examined.

280 g of purified components indicated that both glycosidase-treated and untreated FVa(IIa) expressed ide

281 Experiments with glycosidase-treated fetuin, gp120, and CD4 revealed that

282 Analyses of the APC-catalyzed cleavage of glycosidase-treated FV at Arg(306), the initial cleavage

283 When glycosidase-treated FV was analyzed in an aPTT (activate

284 tylgalactosamine, and N-glycosylated but not glycosidase-treated model glycoproteins bound DltA.

285 Endoglycosidase H and peptide N-glycosidase treatment and cell surface immunoprecipitati

286 Glycosidase treatment that removed O-linked sugars reduc

287 ion site, which is reduced to 26 kDa after N-glycosidase treatment.

288 e can function as a protease-resistant major glycosidase under the conditions of stomach and intestin

289 g Env production, followed by treatment with glycosidases under conditions that preserve Env trimer i

290 H group that, in all other known families of glycosidase using this mechanism, is an aspartate or glu

291 The transiently expressed recombinant human glycosidase was subject to rapid intracellular turnover

292 mannose phosphorylation of several lysosomal glycosidases was observed in morphant lysates, consisten

293 CA in targeting and protecting two lysosomal glycosidases, we have defined a role for the proteolytic

294 Five different glycosidases were detected rapidly within 1 h using disp

295 is rather than the Glu or Asp found in other glycosidases were not apparent.

296 N-glycans can be released by glycosidases, whereas O-glycans are often cleaved by che

297 uding humans, comprising two-sub families of glycosidases which all cleave the chitobiose core of N-l

298 e antibiotics, the availability of macrolide glycosidases, which can be used for the activation of ne

299 repurposed glucose meters to rapidly detect glycosidases, which in turn could be useful to report th

300 of phenotypes in mutants defective for other glycosidases, which trim Gal or Fuc, suggests that XYL1