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5 r five model glycans, ISD produced extensive glycosidic and cross-ring cleavages in the positive ion
7 s that fragments to produce information-rich glycosidic and cross-ring product ions which can be used
10 wine odorant aglycones from odourless grape glycosidic aroma precursors previously isolated from whi
13 ed carbohydrate amino acid core, followed by glycosidic attachment of thymine at C-1, and peptidic li
15 docked state, which requires an unusual syn glycosidic base conformation at A38 for active site asse
16 asic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions
19 from the double-stranded DNA, cleaves the N-glycosidic bond and leaves the C1' hydrolyzed abasic sug
20 formation from 1 involves rotation about the glycosidic bond and that the rate constant for this proc
21 in a high number of distance restraints per glycosidic bond and, consequently, a well-defined struct
24 rns in terms of preferential cleavage of the glycosidic bond between O- and fructose C2 in both inuli
25 es early stage assembly of the acidic labile glycosidic bond between sugar and 2-methylchromone aglyc
26 ol+base)-H]-, resulting from cleavage of the glycosidic bond between the 2'-deoxyribose and base, cor
27 in three-stranded DNA via hydrolysis of the glycosidic bond between the crosslinked base and deoxyri
28 Endoglycosidases F2 and H, which cleave the glycosidic bond between the two primary GlcNAc residues,
29 s (GH) are enzymes that mainly hydrolyze the glycosidic bond between two carbohydrates or a carbohydr
31 e kinetics and thermodynamics of gas-phase N-glycosidic bond cleavage induced by nucleophilic attack
35 n maintaining genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions
36 ase, protects genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions,
37 genic 8-oxoguanine (oxoG) lesion, catalyzing glycosidic bond cleavage of oxoG to initiate base excisi
40 -ethenoadenine (A) lesion, and the rate of N-glycosidic bond cleavage was identical to that of the wi
41 reported accounts that IRMPD results only in glycosidic bond cleavage, the fragmentation of singly pr
47 The glycan-specific ions mainly arose from glycosidic bond cleavages (B, Y, C, and Z ions) in addit
48 vatized glycans predominately generates C1-O glycosidic bond cleavages retaining the charge on the re
49 acts to yield abundant cross-ring cleavages, glycosidic bond cleavages, and combinations of these typ
50 all possible heparin/HS sequences solely by glycosidic bond cleavages, without the need to generate
52 es (G4 and G6 in (rGACGAGUGUCA)(2)) in a syn glycosidic bond conformation and forming a sheared GG pa
53 of the templating base to maintain the anti glycosidic bond conformation in the binary complex in a
54 udouridine synthase, strongly prefer the syn glycosidic bond conformation, while that of the nonreact
55 In both cases, the modified C adopts an anti glycosidic bond conformation; the equilenin distal ring
56 sociated with the nucleophilic cleavage of N-glycosidic bond constitutes a major factor contributing
57 ines by reversible homolytic scission of the glycosidic bond following the dictates of the Fischer-In
58 s a control element in enzymic processes for glycosidic bond formation and hydrolysis are discussed.
61 a modification not directly involved in the glycosidic bond formation, 6F-N-acetyl-d-galactosamine (
63 containing the characteristic ribose-ribose glycosidic bond formed during poly(ADP-ribosyl)ation.
64 onfiguration is retained following gas-phase glycosidic bond fragmentation during tandem mass spectro
65 ism in which the key amino acids driving the glycosidic bond hydrolysis act as catalytic acid/base an
69 be facilitated by binding the bases with the glycosidic bond in the anti and syn conformation, respec
70 s the polyoxygenated saccharide and a labile glycosidic bond in the nucleosides, these reactions can
71 and two hydrogen bond acceptors because the glycosidic bond is C-C rather than C-N as in uridine.
72 te transition state in which cleavage of the glycosidic bond is coupled to the transfer of a proton f
73 displacement mechanism: the cleavage of the glycosidic bond is facilitated by the nucleophilic parti
74 lity of the deficient variants to cleave the glycosidic bond of beta-NAD(+) into nicotinamide and ADP
77 ine DNA glycosylase (Tdg), which cleaves the glycosidic bond of the bases to give potentially harmful
79 ein, we disclose that compounds having the O-glycosidic bond replaced with carbon linkages had improv
80 on on the mannoside phenyl ring ortho to the glycosidic bond results in large potency enhancements se
82 ces induce differences in the sugar puckers, glycosidic bond rotation, and backbone conformations.
83 iring, base stacking, backbone conformation, glycosidic bond rotation, and sugar puckering in the stu
86 g mispair formation, but it also renders the glycosidic bond susceptible to base cleavage by DNA repa
88 In contrast, the beta-D-GlcNAc-(1-->3)-D-Gal glycosidic bond that connects the two Le(x) trisaccharid
89 esions and catalyzes the hydrolysis of the N-glycosidic bond to initiate the base excision repair pat
90 osine, and catalyzes the hydrolysis of the N-glycosidic bond to release the lesion base and initiate
91 n bonds, permitting dA* to rotate around the glycosidic bond to syn and incorporate dT via a Hoogstee
92 e on the nucleophilic aspartate (264) as the glycosidic bond to the aspartate is broken during the br
93 ss units to its molecular mass and makes the glycosidic bond unusually labile during mass spectral an
96 xist in anti or syn conformations around the glycosidic bond when paired opposite to U or G in the co
98 tivities: N-glycosylase (hydrolysis of the N-glycosidic bond) and AP lyase (elimination of the 3'-pho
100 h a 3-OH group and a 4-OH group (or alpha1-4-glycosidic bond) at the acceptor subsite +1 for the cata
102 n by the C2-alkoxide, an essentially cleaved glycosidic bond, and a slight shortening of the endocycl
104 f uracil-DNA glycosylase hydrolysis of the N-glycosidic bond, converting 2'-deoxyuridine in DNA to an
106 ed in cellular DNA due to instability of the glycosidic bond, particularly at purines and various oxi
107 tion through a spontaneous hydrolysis of the glycosidic bond, the ability of Rev1 to stabilize an aba
109 )-meG adopts an anti conformation around its glycosidic bond, with the methyl group in the proximal o
117 thesis of the so-called difficult classes of glycosidic bond: the 2-deoxy-beta-glycopyranosides, the
118 uanosine adopts a syn conformation about the glycosidic bond; thermal melting studies and molecular m
120 degrees of conformational change around the glycosidic bonds and subsequently alter its function as
121 catalyze the highly specific biosynthesis of glycosidic bonds and, as such, are important both as dru
122 n of SEC and FTIR data showed that alpha-1,6-glycosidic bonds are more frequently split in pressurize
123 osyl urea derivatives, in which the O- and N-glycosidic bonds are replaced with the urea-glycosidic l
124 pore cortex PG and catalyzes the cleavage of glycosidic bonds between N-acetylmuramic acid (NAM) and
126 nsition states are late with largely cleaved glycosidic bonds coupled to pyranosyl ring flattening ((
127 on is reversed by hydrolases that cleave the glycosidic bonds either between ADP-ribose units or betw
133 opening polymerization to generate multiple glycosidic bonds in one simple chemical step, allowing u
134 structurally related enzymes that hydrolyze glycosidic bonds in pectin, and are important extracellu
135 s (LPMOs) catalyze the oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides, such a
136 e of electrons to oxidize the C1 position of glycosidic bonds in starch substrates, but not in cellul
138 ases (LPMO10s) use redox chemistry to cleave glycosidic bonds in the two foremost recalcitrant polysa
139 ncorrelated rotations are observed about the glycosidic bonds of a partially de-methyl-esterified dec
140 talline cellulose and hydrolyze the beta-1,4-glycosidic bonds of cellulose to produce fermentable sug
141 s suggested that phenolic hydroxyls, but not glycosidic bonds of melanoidin-bound phenolics are cleav
142 yses reveal that correlated rotations around glycosidic bonds of monosaccharide subunits at and immed
143 that catalyse the endohydrolysis of beta-1,4-glycosidic bonds of partially acetylated chitosan to rel
144 soamylase is essential to debranch alpha-1,6-glycosidic bonds of starch, yielding linear amylodextrin
146 Glucosidases are enzymes that hydrolyze beta-glycosidic bonds to release non-reducing terminal glucos
147 ermore, lysozyme catalyzed the hydrolysis of glycosidic bonds to the end of the linear substrate but
148 enzymes that catalyze oxidative cleavage of glycosidic bonds using molecular oxygen and an external
149 ttention owing to their abilities to disrupt glycosidic bonds via oxidation instead of hydrolysis and
150 saccharides linked through 1,3- and 1,4-beta glycosidic bonds with subtle differences in structure th
151 fragment ions predominantly from cleavage of glycosidic bonds without breaking the peptide bond.
152 The two most stable structures had trans glycosidic bonds, but distinct pairing geometries, i.e.
153 atalytic itineraries" during the cleavage of glycosidic bonds, illustrating the relationship between
155 ectivity in the formation of 1,2-cis-2-amino glycosidic bonds, the glycosylation reaction is hampered
156 ither cross-ring cleavages or rupture of the glycosidic bonds, thereby allowing an unambiguous assign
157 de thioglycosides containing 1,2-cis-2-amino glycosidic bonds, via cationic nickel-catalyzed glycosyl
158 ion 1175-1157cm(-1), linked with breakage of glycosidic bonds, were the most useful for diagnostic mo
159 nd sialic acid receptors linked via alpha2-3 glycosidic bonds, while human-adapted hemagglutinins bin
164 linked GalNAc polymers that lack significant glycosidic branching and may be connected by glycine pep
165 l chain C-O, C-N, and C-C bond cleavages and glycosidic C-O and cross ring cleavages, thus providing
169 nteraction was observed by the change in the glycosidic CO, and the CH stretch vibrations of the treh
170 erties, permeabilities, zeta potentials, and glycosidic compositions of capsules from young and old c
172 ymorphisms of G-quadruplexes relate to these glycosidic conformational patterns and the lengths of th
174 on among species were assigned as kaempferol glycosidic conjugates, with kaempferol-3-O-[glucopyranos
175 cones show higher bioavailability than their glycosidic counterparts and thus may have greater potenc
178 strong sensitizer, so this compound and its glycosidic derivative can contribute to the allergic pot
184 e charge results in the generation of C-type glycosidic fragments, highly informative A-type cross-ri
185 ed oligopeptide tree structure appended with glycosidic groups at its multiple N-termini were investi
187 a nonreducing end GlcNAc that has a beta1-6-glycosidic link and that are analogous to either N-glyca
188 For the alpha-O-GalNAc-Ser derivative, the glycosidic linkage adopts a high-energy conformation, ba
189 tions from AF4, carbohydrate composition and glycosidic linkage analysis for the dominating populatio
190 iomers possessing the natural sugar in alpha-glycosidic linkage are the most potent inhibitors of the
192 flight mass spectrometry confirmed a direct glycosidic linkage between CPS and PG and showed that a
193 s involved were the synthesis of the 1,2-cis-glycosidic linkage between galactose and the linker (spa
195 re symmetrically joined, by a "head-to-head" glycosidic linkage between their carbonyl groups (Chart
196 trehalose oxygen atoms most distant from the glycosidic linkage fluctuated around 7.5 x 10(-14) m(2)/
197 ) that sulfur-for-oxygen substitution in the glycosidic linkage fundamentally alters the energeticall
198 ds a disaccharide that closely resembles the glycosidic linkage in the polylegionaminic acid from the
201 ygromycin B identified an orientation of one glycosidic linkage of hygromycin B consistent with metal
204 dihedral angles has been determined for each glycosidic linkage relevant for the conformational prefe
206 terized and revealed that in the complex the glycosidic linkage torsion angles between the two reduci
207 free energy landscapes obtained for the same glycosidic linkage within different oligosaccharides.
208 ural substrates harboring the Fucalpha1-2Gal glycosidic linkage, a xyloglucan-derived nonasaccharide,
209 instance, the sugar is aminoglucose in beta-glycosidic linkage, and in the other, two enantiomers ha
210 n the sugar itself, the presence and form of glycosidic linkage, and the environment in the crystal,
211 uctural information, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacki
219 te preference for alpha(1-6) over alpha(1-4) glycosidic linkages and produces glucose from isomaltose
220 nt structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.
221 e mutant glycosidases, that can readily form glycosidic linkages are addressing a lack of a wide rang
222 enzyl, and p-bromobenzyl ethers, esters, and glycosidic linkages are stable to these reaction conditi
223 glycoconjugates bearing the 1,2-cis-2-amino glycosidic linkages because the saccharide thioglycoside
224 ymers of different lengths containing labile glycosidic linkages between monomer units necessitating
225 monosaccharide composition, the position of glycosidic linkages between monosaccharides, and the pos
226 an be characterized by the torsion angles of glycosidic linkages between relatively rigid carbohydrat
227 matic detection and annotation of sugars and glycosidic linkages between sugar units and to proteins,
230 a reduction of alpha(1-->6) and alpha(1-->2) glycosidic linkages illustrating a reduced degree of bra
231 complementary specificities to hydrolyze the glycosidic linkages in agarose, a linear polymer compris
234 rize anomeric configurations of newly formed glycosidic linkages in complex oligosaccharide synthesis
235 Cellobiohydrolases processively hydrolyze glycosidic linkages in individual polymer chains of cell
236 is a paradigm for the study of other unusual glycosidic linkages in model and parasitic organisms.
241 enzyme known to catalyse hydrolysis of the O-glycosidic linkages of ADP-ribose polymers, thereby reve
242 aride composed of partially acetylated 1-->4 glycosidic linkages of N-acetylgalactosamine and N-acety
243 s ability to catalyze the hydrolysis of beta-glycosidic linkages once endocytosed, whereas equal conc
244 C-H protons is indicative of the position of glycosidic linkages or other substituents and can be rea
245 fficient and stereoselective construction of glycosidic linkages remains one of the most formidable c
247 ately 10(7) y),(5) of the 1-4 "head-to-tail" glycosidic linkages that join the common glucose polymer
250 trols stereoselective formation of 1,2-trans-glycosidic linkages via the arming participation effect.
252 ortant glucoside containing multiple 1,2-cis-glycosidic linkages with complete anomeric control by us
253 ransferase in the GT41 family that creates N-glycosidic linkages with glucose and galactose at aspara
254 rocycles, melamine and barbituric acid, form glycosidic linkages with ribose and ribose-5-phosphate i
255 can show that the torsions of the different glycosidic linkages within the GPI tetrasaccharide can b
257 ha-glucan with (alpha1-->3) and (alpha1-->6) glycosidic linkages, and was similar in structure to a p
258 sis of their monosaccharide building blocks, glycosidic linkages, chain length, as well as additional
260 -glycosidic bonds are replaced with the urea-glycosidic linkages, has recently emerged with applicati
271 ains a polycyclic ring system (rings A-D), a glycosidic moiety at C4, and a pendant ring (E-ring) at
272 d of a polycyclic ring system (rings A-D), a glycosidic moiety at the C4 position, and a pendent ring
273 ising from the C-ring, the D-ring, or the C4 glycosidic moiety were observed with either enzyme, sugg
274 residue was found to be too distant from the glycosidic oxygen (>4.3 A) to serve directly as a genera
275 thuss proton shuttle between Glu-796 and the glycosidic oxygen, permitting this residue to serve as t
276 riables, such as coordination numbers of the glycosidic oxygen, yielded a variety of chemical reactio
278 nsted acidic OH-defect sites and constrained glycosidic oxygens (i.e., those juxtaposed adjacent to t
280 eral acid/base Glu-288 nearest the predicted glycosidic position, whereas the open conformation possi
282 The aim of this work was to identify the glycosidic precursors of the key volatile compounds resp
286 ne bearing redox-active osmium complexes and glycosidic residues (lactose) is used to create a self-a
287 peating ADP-ribose units linked via a unique glycosidic ribose-ribose bond, and is synthesized from N
288 f long chains of ADP-ribose units, linked by glycosidic ribose-ribose bonds, and is critical for a wi
294 After a glycan search is complete, each glycosidic torsion angle distribution is displayed in te
295 wever, for K14M with adenyl nucleotides, the glycosidic torsion angle was 30 +/- 5 degrees with MgATP
296 omplexes, GKy.MgADP.[u-(13)C]GMP, the guanyl glycosidic torsion angle, chi, is 51 +/- 5 degrees for R
298 ww.glycanstructure.org, is a database of the glycosidic torsion angles derived from the glycan struct
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