ライフサイエンスコーパス: glycosidic bond

1 of the l-histidine through a hydrolyzable N-glycosidic bond.

2 cid catalyst responsible for cleavage of the glycosidic bond.

3 ovements that occur during cleavage of the N-glycosidic bond.

4 non-paired adenosines and cleavage of the N-glycosidic bond.

5 to serine/threonine residues via an O-linked glycosidic bond.

6 ne closer to the cleavable substrate beta1,4-glycosidic bond.

7 rogen bond was directly across from the dCTP glycosidic bond.

8 Gal attached to the O-linked GlcNAc by a 1-3 glycosidic bond.

9 the anomeric-to-anomeric alpha, beta-1",11'-glycosidic bond.

10 involves the breakage and re-formation of a glycosidic bond.

11 was in the syn(chi)() conformation about the glycosidic bond.

12 substrate show events after cleavage of the glycosidic bond.

13 t base by catalyzing the hydrolysis of the N-glycosidic bond.

14 enzyme are induced by the hydrolysis of the glycosidic bond.

15 sidue for assisting in the hydrolysis of the glycosidic bond.

16 both bind in an anti conformation about the glycosidic bond.

17 e ligands at several positions including the glycosidic bond.

18 e their excision through hydrolysis of the N-glycosidic bond.

19 lution is predominantly direct cleave of the glycosidic bond.

20 arbon was retained on cleavage of the middle glycosidic bond.

21 sidue and thereby facilitate cleavage of the glycosidic bond.

22 lting in a Schiff base intermediate at the N-glycosidic bond.

23 ell characterized in cells due to its labile glycosidic bond.

24 the hyaluronic acid polymer at the beta-1,4 glycosidic bond.

25 talysis to achieve selective cleavage of the glycosidic bond.

26 uite indirect because of the lability of the glycosidic bond.

27 lly compatible with the presence of multiple glycosidic bonds.

28 (13)C coupling constants measured across the glycosidic bonds.

29 es a cyclic beta-glucan lacking beta-(1-->6)-glycosidic bonds.

30 nose units (D-GalpA) linked by alpha-(1-->4) glycosidic bonds.

31 t rotamer orientations about their beta(1,6) glycosidic bonds.

32 , that are linked by amide, ether, ester, or glycosidic bonds.

33 the LPMO mechanism for oxidative cleavage of glycosidic bonds.

34 es may utilize in catalyzing the cleavage of glycosidic bonds.

35 Due to the lability of the glycosidic bond, 8-nitrodG cannot be incorporated into o

36 f other dipterans in the linkage at a single glycosidic bond, a distinction with significant structur

37 risaccharide is presented in which all three glycosidic bonds, a 1,2-cis-equatorial, a 1,2-trans-axia

38 Hence, the glycosidic bonds act as mechanical levers, driving the c

39 with muramidase resulted in cleavage of the glycosidic bonds adjacent to muramic acid replaced by pe

40 The inherent flexibility around their glycosidic bonds allows them to easily assume a variety

41 om the formal hydrolysis of the nucleotides' glycosidic bonds, along with a variety of oxidized abasi

42 trong hyperconjugation between the elongated glycosidic bond and both of the C2'-H2' bonds.

43 MCDTs for alkali metal ion dissociation and glycosidic bond and cross-ring cleavages were resolved f

44 tation of the nicotinamide ring around the N-glycosidic bond and displacement of C1 of 6PG, facilitat

45 from the double-stranded DNA, cleaves the N-glycosidic bond and leaves the C1' hydrolyzed abasic sug

46 ows the phosphate group poised to attack the glycosidic bond and promote phosphorolysis.

47 formation from 1 involves rotation about the glycosidic bond and that the rate constant for this proc

48 on-canonical pair, with one G syn around the glycosidic bond and the other anti.

49 t base excision may occur by cleavage of the glycosidic bond and then attachment of Lys249.

50 in a high number of distance restraints per glycosidic bond and, consequently, a well-defined struct

51 ing cycle, which likely includes energy from glycosidic bonds and other sources.

52 degrees of conformational change around the glycosidic bonds and subsequently alter its function as

53 catalyze the highly specific biosynthesis of glycosidic bonds and, as such, are important both as dru

54 tivities: N-glycosylase (hydrolysis of the N-glycosidic bond) and AP lyase (elimination of the 3'-pho

55 n by the C2-alkoxide, an essentially cleaved glycosidic bond, and a slight shortening of the endocycl

56 are both in the anti conformation about the glycosidic bond, and both ribose rings are in approximat

57 ge backbone' conformation, wherein the inter-glycosidic bond angles were held constant at the mean of

58 asic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions

59 When the glycosidic bonds are equatorial (e), the torque is zero,

60 n of SEC and FTIR data showed that alpha-1,6-glycosidic bonds are more frequently split in pressurize

61 osyl urea derivatives, in which the O- and N-glycosidic bonds are replaced with the urea-glycosidic l

62 eonine residues of a protein via an O-linked glycosidic bond) are largely unknown.

63 presenting three of the four main classes of glycosidic bond, are formed with thioglycoside donors ac

64 ering by the value of the Psi angle for this glycosidic bond, are populated in solution.

65 f the cofactor to allow rotation about the N-glycosidic bond as it is reduced in the hydride transfer

66 read class of hydrolases and cleave beta-1,4-glycosidic bonds as part of their function.

67 the dA(6) base protons are typical of a syn glycosidic bond at the modified base.

68 degradation technique that only cleaves the glycosidic bond at the reducing end by beta-elimination

69 bose moiety of the substrate and cleaves the glycosidic bond at the very last stage.

70 h a 3-OH group and a 4-OH group (or alpha1-4-glycosidic bond) at the acceptor subsite +1 for the cata

71 o group with the pyrimidine ring, the N1-C1' glycosidic bond bends by approximately 19 degrees out of

72 acetolysis susceptible, indicative of a 1,6 glycosidic bond between CPS and the GlcNAc C-6.

73 NagZ hydrolyzes the beta-1,4 glycosidic bond between N-acetylglucosamine and anhydro-

74 alyltransferase catalyzes the formation of a glycosidic bond between N-acetylneuraminic acid and the

75 rns in terms of preferential cleavage of the glycosidic bond between O- and fructose C2 in both inuli

76 es early stage assembly of the acidic labile glycosidic bond between sugar and 2-methylchromone aglyc

77 ol+base)-H]-, resulting from cleavage of the glycosidic bond between the 2'-deoxyribose and base, cor

78 t excise the damaged base by cleavage of the glycosidic bond between the base and the DNA sugar-phosp

79 in three-stranded DNA via hydrolysis of the glycosidic bond between the crosslinked base and deoxyri

80 formation, concomitant with cleavage of the glycosidic bond between the residue undergoing epimeriza

81 Endoglycosidases F2 and H, which cleave the glycosidic bond between the two primary GlcNAc residues,

82 s (GH) are enzymes that mainly hydrolyze the glycosidic bond between two carbohydrates or a carbohydr

83 pore cortex PG and catalyzes the cleavage of glycosidic bonds between N-acetylmuramic acid (NAM) and

84 The two most stable structures had trans glycosidic bonds, but distinct pairing geometries, i.e.

85 city of the alpha-face on replacement of the glycosidic bond by the hydroxylamine linkage.

86 One of these LPMOs cleaves glycosidic bonds by oxidation of the C1 carbon, whereas

87 rom this structure, it may be concluded that glycosidic bond cleavage and the induced fit conformatio

88 y is initiated by spontaneous or enzymatic N-glycosidic bond cleavage creating an abasic or apurinic-

89 e kinetics and thermodynamics of gas-phase N-glycosidic bond cleavage induced by nucleophilic attack

90 by its insertion into the active site where glycosidic bond cleavage is catalyzed.

91 N-Glycosidic bond cleavage is much slower, taking place on

92 NDTs catalyze N-glycosidic bond cleavage of 2'-deoxynucleosides via a co

93 n maintaining genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions

94 ase, protects genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions,

95 genic 8-oxoguanine (oxoG) lesion, catalyzing glycosidic bond cleavage of oxoG to initiate base excisi

96 RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2'-deoxyribonucleosid

97 RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2'-deoxyribonucleosid

98 Nonetheless, the glycosidic bond cleavage step was not affected.

99 g by UDG have been studied in the absence of glycosidic bond cleavage using substrate analogues conta

100 -ethenoadenine (A) lesion, and the rate of N-glycosidic bond cleavage was identical to that of the wi

101 reported accounts that IRMPD results only in glycosidic bond cleavage, the fragmentation of singly pr

102 rate 2'-deoxyguridine (dU) residue abrogates glycosidic bond cleavage, thereby leading to the formati

103 ergy barrier and largest exothermicity for N-glycosidic bond cleavage.

104 lease of the abasic product is faster than N-glycosidic bond cleavage.

105 lyzed protonation of the nucleobase promotes glycosidic bond cleavage.

106 ielded ions characteristic of cross-ring and glycosidic bond cleavage.

107 sion deoxyribose participate in catalysis of glycosidic bond cleavage.

108 resistant to both enzyme- and acid-catalyzed glycosidic bond cleavage.

109 binding and base flipping in the absence of glycosidic bond cleavage.

110 ylation of crystalline cellulose, leading to glycosidic bond cleavage.

111 The glycan-specific ions mainly arose from glycosidic bond cleavages (B, Y, C, and Z ions) in addit

112 The relative dissociation thresholds of glycosidic bond cleavages and cross-ring cleavages were

113 The results suggest that glycosidic bond cleavages are charge-induced while cross

114 vatized glycans predominately generates C1-O glycosidic bond cleavages retaining the charge on the re

115 The activation barriers of glycosidic bond cleavages were found to depend on the si

116 acts to yield abundant cross-ring cleavages, glycosidic bond cleavages, and combinations of these typ

117 all possible heparin/HS sequences solely by glycosidic bond cleavages, without the need to generate

118 accharide and disaccharide ions derived from glycosidic bond cleavages.

119 es (G4 and G6 in (rGACGAGUGUCA)(2)) in a syn glycosidic bond conformation and forming a sheared GG pa

120 o modes, and the alternation, if any, of the glycosidic bond conformation between syn and anti.

121 of the templating base to maintain the anti glycosidic bond conformation in the binary complex in a

122 udouridine synthase, strongly prefer the syn glycosidic bond conformation, while that of the nonreact

123 e of the modified template adenine with anti glycosidic bond conformation, without disturbing critica

124 In both cases, the modified C adopts an anti glycosidic bond conformation; the equilenin distal ring

125 Both syn and anti glycosidic bond conformations are energetically feasible

126 sociated with the nucleophilic cleavage of N-glycosidic bond constitutes a major factor contributing

127 f uracil-DNA glycosylase hydrolysis of the N-glycosidic bond, converting 2'-deoxyuridine in DNA to an

128 nsition states are late with largely cleaved glycosidic bonds coupled to pyranosyl ring flattening ((

129 ee enzymatic activities, hydrolysis of the N-glycosidic bond (DNA glycosylase), beta-elimination (AP

130 on is reversed by hydrolases that cleave the glycosidic bonds either between ADP-ribose units or betw

131 eometric changes in the anions show that the glycosidic bond exhibits little change with excess charg

132 ines by reversible homolytic scission of the glycosidic bond following the dictates of the Fischer-In

133 , is described that allows for hydrolysis of glycosidic bonds for both hexose- and N-acetylhexosamine

134 s a control element in enzymic processes for glycosidic bond formation and hydrolysis are discussed.

135 Formidable challenges include glycosidic bond formation between ribose and the canonic

136 They catalyze a glycosidic bond formation between sugar donors and sugar

137 Both the C2-nitrogen transfer and the glycosidic bond formation proceed stereoselectively, all

138 a modification not directly involved in the glycosidic bond formation, 6F-N-acetyl-d-galactosamine (

139 on of an external nucleophile and subsequent glycosidic bond formation.

140 rides and the development of new methods for glycosidic bond formation.

141 g protecting groups on the donor favor alpha-glycosidic bond formation.

142 containing the characteristic ribose-ribose glycosidic bond formed during poly(ADP-ribosyl)ation.

143 nvolving excision of the nucleobase at the N-glycosidic bond forms abasic sites.

144 onfiguration is retained following gas-phase glycosidic bond fragmentation during tandem mass spectro

145 leavage channels that "protect" the N-linked glycosidic bond from cleavage.

146 protecting group is a bulky silyl ether or a glycosidic bond; however, even with a 3-O-benzyl ether,

147 s of AAG-catalyzed (k(st)) and spontaneous N-glycosidic bond hydrolysis (k(non)) for damaged and unda

148 ism in which the key amino acids driving the glycosidic bond hydrolysis act as catalytic acid/base an

149 Previous studies show that N-glycosidic bond hydrolysis follows a stepwise (S(N)1) me

150 the active site by exclusively impairing the glycosidic bond hydrolysis step.

151 icient despite the relatively slow rate of N-glycosidic bond hydrolysis.

152 cific excision of the thymine base through N-glycosidic bond hydrolysis.

153 atalytic itineraries" during the cleavage of glycosidic bonds, illustrating the relationship between

154 ith restricted diffusion (rocking) about the glycosidic bond in addition to sugar repuckering was cap

155 ejects the proton analogous to the cytosine glycosidic bond in DNA.

156 calar couplings and conformations around the glycosidic bond in oligonucleotides.

157 AdoCbl), in which the configuration of the N-glycosidic bond in the Ado ligand is inverted [(alpha-ri

158 be facilitated by binding the bases with the glycosidic bond in the anti and syn conformation, respec

159 eity involving a syn-anti equilibrium of the glycosidic bond in the modified adenine residue.

160 s the polyoxygenated saccharide and a labile glycosidic bond in the nucleosides, these reactions can

161 topological arrangement of the two bases and glycosidic bonds in a given base-pair.

162 G and AlkA are therefore able to hydrolyze O-glycosidic bonds in addition to N-glycosyl bonds.

163 Cellulase enzymes cleave glycosidic bonds in cellulose to produce cellobiose via

164 dicating the ability of MGIIa_P to hydrolyse glycosidic bonds in complex sugars in PRE.

165 nsertion and subsequent elimination to break glycosidic bonds in crystalline cellulose.

166 To achieve cleavage of the glycosidic bonds in host glycans, S. pneumoniae deploys

167 opening polymerization to generate multiple glycosidic bonds in one simple chemical step, allowing u

168 structurally related enzymes that hydrolyze glycosidic bonds in pectin, and are important extracellu

169 s (LPMOs) catalyze the oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides, such a

170 e of electrons to oxidize the C1 position of glycosidic bonds in starch substrates, but not in cellul

171 -xylanases (xylanases) hydrolyse the beta1,4 glycosidic bonds in the backbone of xylan.

172 ctor analogs with thio linkages instead of O-glycosidic bonds in the oligosaccharide backbone.

173 ases (LPMO10s) use redox chemistry to cleave glycosidic bonds in the two foremost recalcitrant polysa

174 o evidence that conformational strain of the glycosidic bond induced by serine pinching plays a major

175 ons indicate that the conformation about the glycosidic bond is anti.

176 However, when the glycosidic bond is axial (a), torque is generated, causi

177 and two hydrogen bond acceptors because the glycosidic bond is C-C rather than C-N as in uridine.

178 ting agent is that in which the newly formed glycosidic bond is cis to the epoxide moiety.

179 te transition state in which cleavage of the glycosidic bond is coupled to the transfer of a proton f

180 KIE (=1.201 +/- 0.021) indicate that (i) the glycosidic bond is essentially completely broken in the

181 displacement mechanism: the cleavage of the glycosidic bond is facilitated by the nucleophilic parti

182 ite adjacent to the anomeric carbon of the N-glycosidic bond is suggestive of direct attack by water,

183 The wild-type enzyme cleaves the N-glycosidic bond, leaving the ribose ring in the flipped

184 nitial substrate; with increasing numbers of glycosidic bonds, less glucose is formed.

185 c activity of ChiA was specific for beta,1-4 glycosidic bonds located between GlcNAc monomers in chit

186 low-mass negative ions containing the intact glycosidic bond (m/z 225, 207, 189, 165, 164, 139), whic

187 The enzymatic formation of glycosidic bonds may be catalyzed by the transfer of the

188 re due to the metabolic instability of the O-glycosidic bond (O-mannosides).

189 echanism to catalyze the hydrolysis of the N-glycosidic bond of 2'-deoxyuridine (2'-dUrd) in DNA as t

190 The metabolic instability in vivo of the glycosidic bond of 2,5, 6-trichloro-1-(beta-D-ribofurano

191 The reaction involves hydrolysis of the N-glycosidic bond of a particular deoxyguanosine residue,

192 have a syn conformational preference at the glycosidic bond of A, moA substitution results in stabil

193 ting the conformational preferences of the N-glycosidic bond of adenosine within DNA.

194 The half-life of the glycosidic bond of an FoU residue in single-stranded DNA

195 lity of the deficient variants to cleave the glycosidic bond of beta-NAD(+) into nicotinamide and ADP

196 groups showed that DspB hydrolyzed the 1-->4 glycosidic bond of beta-substituted N-acetylglucosamine,

197 ely recognize the anti conformation of the N-glycosidic bond of cAMP.G.U pairs occur frequently and h

198 uracil DNA glycosylase (UDG) hydrolyzes the glycosidic bond of deoxyuridine in DNA by a remarkable m

199 Uracil DNA glycosylase (UDG) cleaves the glycosidic bond of deoxyuridine in DNA using a hydrolyti

200 a powerful N-glycohydrolase that cleaves the glycosidic bond of deoxyuridine in DNA.

201 ir pathway, the hydrolytic cleavage of the N-glycosidic bond of deoxyuridine in DNA.

202 th the Ser88 pinching finger) shows that the glycosidic bond of dU has been cleaved, and that the enz

203 trate but instead by the reactivity of the N-glycosidic bond of each substrate.

204 nd 26, hydrolyze glucomannan by cleaving the glycosidic bond of mannosides at the -1 subsite.

205 ate group of the C-domain to the scissile, N-glycosidic bond of NAD suggest plausible modes of cataly

206 at LytB cleaves the GlcNAc-beta-(1,4)-MurNAc glycosidic bond of peptidoglycan building units.

207 (UDG) catalyzes hydrolytic cleavage of the N-glycosidic bond of premutagenic uracil residues in DNA b

208 s a consequence of the C-C (rather than C-N) glycosidic bond of pseudouridine, the otherwise common d

209 The glycosidic bond of psi32 is in the anti configuration an

210 ine DNA glycosylase (Tdg), which cleaves the glycosidic bond of the bases to give potentially harmful

211 Rotation about the glycosidic bond of the dCTP residue to this abnormal pos

212 indicate conformational averaging about the glycosidic bond of the nicotinamide nucleotide.

213 ncorrelated rotations are observed about the glycosidic bonds of a partially de-methyl-esterified dec

214 hydrolase (PARG) catalyzes the hydrolysis of glycosidic bonds of ADP-ribose polymers, producing monom

215 ChEWL catalyzes the hydrolysis of the glycosidic bonds of bacterial peptidoglycans and chitin-

216 uirements for the hydrolysis of the beta-1,4 glycosidic bonds of cellulose is an essential prerequisi

217 talline cellulose and hydrolyze the beta-1,4-glycosidic bonds of cellulose to produce fermentable sug

218 lividans performs hydrolysis of the beta-1,4-glycosidic bonds of cellulose, with net retention of ano

219 s suggested that phenolic hydroxyls, but not glycosidic bonds of melanoidin-bound phenolics are cleav

220 yses reveal that correlated rotations around glycosidic bonds of monosaccharide subunits at and immed

221 that catalyse the endohydrolysis of beta-1,4-glycosidic bonds of partially acetylated chitosan to rel

222 soamylase is essential to debranch alpha-1,6-glycosidic bonds of starch, yielding linear amylodextrin

223 The enzymatic cleavage of the nicotinamide-glycosidic bond on nicotinamide adenine dinucleotide (NA

224 he fungus Trichoderma reesei that hydrolyzes glycosidic bonds on cellulose randomly.

225 ed in cellular DNA due to instability of the glycosidic bond, particularly at purines and various oxi

226 an important fungal ligand for SP-D and that glycosidic bond patterns alone can determine if an exten

227 Nucleosides fragmented at the N-glycosidic bond provide nucleobase and/or ribose or 2'-d

228 ides, IRMPD causes extensive cleavage of the glycosidic bonds, providing structural information about

229 CH or sugar edge) and the orientation of the glycosidic bonds relative to the hydrogen bonds (cis or

230 ein, we disclose that compounds having the O-glycosidic bond replaced with carbon linkages had improv

231 ease selectivity of alpha-1,4 over alpha-1,6 glycosidic bonds, resulting in fewer alpha-1,6 linked re

232 on on the mannoside phenyl ring ortho to the glycosidic bond results in large potency enhancements se

233 The presence of the glycosidic bond results in the stereoselective induction

234 ces induce differences in the sugar puckers, glycosidic bond rotation, and backbone conformations.

235 iring, base stacking, backbone conformation, glycosidic bond rotation, and sugar puckering in the stu

236 , for example, that Cel7A cleaves about four glycosidic bonds/s during processive hydrolysis.

237 N-glycosidic bond scission is then facilitated by a backbo

238 Thus, hTDG specificity depends on N-glycosidic bond stability, and the discrimination agains

239 be more selective and also possess increased glycosidic bond stability.

240 ase cleavage is dependent on the intrinsic N-glycosidic bond stability.

241 omodeoxyuridine, dT) or have a more stable N-glycosidic bond (such as dT).

242 g mispair formation, but it also renders the glycosidic bond susceptible to base cleavage by DNA repa

243 physiologically relevant reverse reaction of glycosidic bond synthesis and thereby require prior know

244 The vast majority of glycosidic-bond synthesis in nature is performed by glyc

245 Cleavage of the N-glycosidic bond that connects the nucleobase to the back

246 In contrast, the beta-D-GlcNAc-(1-->3)-D-Gal glycosidic bond that connects the two Le(x) trisaccharid

247 tion through a spontaneous hydrolysis of the glycosidic bond, the ability of Rev1 to stabilize an aba

248 Following cleavage of the glycosidic bond, the liberated hemiacetal spontaneously

249 ectivity in the formation of 1,2-cis-2-amino glycosidic bonds, the glycosylation reaction is hampered

250 thesis of the so-called difficult classes of glycosidic bond: the 2-deoxy-beta-glycopyranosides, the

251 ither cross-ring cleavages or rupture of the glycosidic bonds, thereby allowing an unambiguous assign

252 uanosine adopts a syn conformation about the glycosidic bond; thermal melting studies and molecular m

253 esions and catalyzes the hydrolysis of the N-glycosidic bond to initiate the base excision repair pat

254 catalyzing the hydrolytic cleavage of the N-glycosidic bond to release the damaged nucleobase.

255 osine, and catalyzes the hydrolysis of the N-glycosidic bond to release the lesion base and initiate

256 n bonds, permitting dA* to rotate around the glycosidic bond to syn and incorporate dT via a Hoogstee

257 e on the nucleophilic aspartate (264) as the glycosidic bond to the aspartate is broken during the br

258 rate constant for enzymatic cleavage of the glycosidic bond to the strongly basic trifluoroethoxide

259 Glucosidases are enzymes that hydrolyze beta-glycosidic bonds to release non-reducing terminal glucos

260 ermore, lysozyme catalyzed the hydrolysis of glycosidic bonds to the end of the linear substrate but

261 allography and NMR, between the nicotinamide glycosidic bond torsion angle (anti/syn) and the stereos

262 e for an intermediate conformation about the glycosidic bond, unlike in the A(3)AR/3 complex, which f

263 ss units to its molecular mass and makes the glycosidic bond unusually labile during mass spectral an

264 demonstration of the anomeric memory of the glycosidic bond upon fragmentation.

265 enzymes that catalyze oxidative cleavage of glycosidic bonds using molecular oxygen and an external

266 ttention owing to their abilities to disrupt glycosidic bonds via oxidation instead of hydrolysis and

267 de thioglycosides containing 1,2-cis-2-amino glycosidic bonds, via cationic nickel-catalyzed glycosyl

268 ing flipping and the conformation of the 1,4-glycosidic bond was observed.

269 ion 1175-1157cm(-1), linked with breakage of glycosidic bonds, were the most useful for diagnostic mo

270 xist in anti or syn conformations around the glycosidic bond when paired opposite to U or G in the co

271 nge results from the torque generated by the glycosidic bonds when a force is applied to the pectin m

272 triguing because the anomeric oxygen forms a glycosidic bond, which means that the reaction must proc

273 ides possess the anti conformation about the glycosidic bond, while in the former, half possess the a

274 G adopted a syn orientation about the glycosidic bond, while the sugar puckers of A and C were

275 nd sialic acid receptors linked via alpha2-3 glycosidic bonds, while human-adapted hemagglutinins bin

276 a predominantly anti conformation about the glycosidic bond with a variety of conformations about th

277 Enzymes in this family hydrolyze beta-1,4-glycosidic bonds with inversion of the stereochemistry a

278 saccharides linked through 1,3- and 1,4-beta glycosidic bonds with subtle differences in structure th

279 w that each G flips independently around the glycosidic bond, with the anti G flipping to syn first.

280 )-meG adopts an anti conformation around its glycosidic bond, with the methyl group in the proximal o

281 roduct ions that result from dissociation at glycosidic bonds, with little occurrence of dissociation

282 fragment ions predominantly from cleavage of glycosidic bonds without breaking the peptide bond.

283 y providing a means for 1,2-trans-equatorial glycosidic bonds without recourse to neighboring group p

284 which selectively cleaves the nicotinamide's glycosidic bond yielding (tz)ADP-ribose.