ライフサイエンスコーパス: glycosidic linkage

1 formed best for the installation of the beta-glycosidic linkage.

2 are distinguished by atomic contacts at the glycosidic linkage.

3 ome of which differ by no more than a single glycosidic linkage.

4 n, regiochemistry and stereochemistry of the glycosidic linkage.

5 esidues, which are present in a mucin-type O-glycosidic linkage.

6 +II) for the reducing end from the scissile glycosidic linkage.

7 on the carbon atom that participates in the glycosidic linkage.

8 was connected to the sequence by a beta(1-6) glycosidic linkage.

9 y known enzymes to be able to hydrolyze this glycosidic linkage.

10 the inversion of the configuration of the N-glycosidic linkage.

11 t high concentration was key to making the C-glycosidic linkage.

12 to be assigned to the nonreducing side of a glycosidic linkage.

13 he natural sugar N-methylfucosamine in alpha-glycosidic linkage.

14 generally limited to catalysis of one unique glycosidic linkage.

15 ch for the stereoselective introduction of a glycosidic linkage.

16 only two unusual conformations at the LacNAc glycosidic linkage.

17 an-II, cleaving all but 1 of its 21 distinct glycosidic linkages.

18 and certain chondroitin sulfates at beta-1,4 glycosidic linkages.

19 ment ions, primarily through dissociation at glycosidic linkages.

20 rmation of the pyranose ring and the type of glycosidic linkages.

21 presence of multiple conformations about the glycosidic linkages.

22 cell wall, contain mannose in either O- or N-glycosidic linkages.

23 s, despite the high local flexibility of the glycosidic linkages.

24 eaction rates depend on the conformations of glycosidic linkages.

25 lysis of alpha-glycosidic linkages than beta-glycosidic linkages.

26 ansferase family members to catalyze beta1-2 glycosidic linkages.

27 ight on gas-phase dissociation mechanisms of glycosidic linkages.

28 e efficient in extracting dyes, but preserve glycosidic linkages.

29 formation in oligosaccharides containing 1,6-glycosidic linkages.

30 saccharides differing in the position of the glycosidic linkage (2alpha-mannobiose, 3alpha-mannobiose

31 ural substrates harboring the Fucalpha1-2Gal glycosidic linkage, a xyloglucan-derived nonasaccharide,

32 idases, which catalyze the hydrolysis of the glycosidic linkages, a function not required for the bio

33 For the alpha-O-GalNAc-Ser derivative, the glycosidic linkage adopts a high-energy conformation, ba

34 tions from AF4, carbohydrate composition and glycosidic linkage analysis for the dominating populatio

35 idase discriminates on the basis of both the glycosidic linkage and the sulfation pattern within its

36 The glycosidic linkages and acetamido side-chains are predic

37 te preference for alpha(1-6) over alpha(1-4) glycosidic linkages and produces glucose from isomaltose

38 nt structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.

39 instance, the sugar is aminoglucose in beta-glycosidic linkage, and in the other, two enantiomers ha

40 n the sugar itself, the presence and form of glycosidic linkage, and the environment in the crystal,

41 types, sugar types, chemical modifications, glycosidic linkages, and anomeric states.

42 ha-glucan with (alpha1-->3) and (alpha1-->6) glycosidic linkages, and was similar in structure to a p

43 iomers possessing the natural sugar in alpha-glycosidic linkage are the most potent inhibitors of the

44 e mutant glycosidases, that can readily form glycosidic linkages are addressing a lack of a wide rang

45 enzyl, and p-bromobenzyl ethers, esters, and glycosidic linkages are stable to these reaction conditi

46 GlycoSeq employs rules of glycosidic linkage as defined by glycan synthetic pathwa

47 For oligosaccharides containing glycosidic linkages at the 6-position (1-->6 linked), va

48 glycoconjugates bearing the 1,2-cis-2-amino glycosidic linkages because the saccharide thioglycoside

49 flight mass spectrometry confirmed a direct glycosidic linkage between CPS and PG and showed that a

50 s involved were the synthesis of the 1,2-cis-glycosidic linkage between galactose and the linker (spa

51 essential glycosyltransferase that forms the glycosidic linkage between N-acetyl muramyl pentapeptide

52 They cleave the glycosidic linkage between N-acetylmuramoyl and N-acetyl

53 The dihedral angles that describe the glycosidic linkage between the A and B rings for the two

54 chondroitin sulfates by cleaving the beta1,4-glycosidic linkage between the glycan units of these pol

55 The key steps are the creation of the glycosidic linkage between the trisaccharide donor, used

56 re symmetrically joined, by a "head-to-head" glycosidic linkage between their carbonyl groups (Chart

57 ymers of different lengths containing labile glycosidic linkages between monomer units necessitating

58 monosaccharide composition, the position of glycosidic linkages between monosaccharides, and the pos

59 -negative bacteria that cleaves the beta-1,4 glycosidic linkages between N-acetylmuramic acid (MurNAc

60 an be characterized by the torsion angles of glycosidic linkages between relatively rigid carbohydrat

61 matic detection and annotation of sugars and glycosidic linkages between sugar units and to proteins,

62 lycoprotein that catalyzes the hydrolysis of glycosidic linkages between terminal sialic acids and ad

63 These 24 substitutions stabilized the N-glycosidic linkage, blocking base loss and subsequent ba

64 ic C-glycosides); and 4) the cleavage of the glycosidic linkage by PNGase A or F (typical for N-glyca

65 couplings originating from both sides of the glycosidic linkage can be used collectively to evaluate

66 sis of their monosaccharide building blocks, glycosidic linkages, chain length, as well as additional

67 Of the two possible glycosidic linkages, chemically, 1,2-trans linkage is re

68 g in relatively long life-times for distinct glycosidic linkage conformations, despite the high local

69 nked glycopeptide analogues that replace the glycosidic linkages extending from the core pentasacchar

70 trehalose oxygen atoms most distant from the glycosidic linkage fluctuated around 7.5 x 10(-14) m(2)/

71 h sugar residues are all connected by native glycosidic linkages found in natural N-glycans.

72 es (GT) to catalyse formation of the various glycosidic linkages found in the polymer.

73 ) that sulfur-for-oxygen substitution in the glycosidic linkage fundamentally alters the energeticall

74 -glycosidic bonds are replaced with the urea-glycosidic linkages, has recently emerged with applicati

75 ain of xylose residues connected by beta-1,4 glycosidic linkages, has remained elusive.

76 that have restricted mobilities around their glycosidic linkages have been employed to determine how

77 uctural information, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacki

78 Using NMR spectroscopy to monitor glycosidic linkage hydrolysis, we find that only 47% of

79 a reduction of alpha(1-->6) and alpha(1-->2) glycosidic linkages illustrating a reduced degree of bra

80 amine 3-O sulfation at the reducing end of a glycosidic linkage imparts resistance to heparinase I, I

81 ure determined for enzymatic cleavage of the glycosidic linkage in a pyrimidine deoxyribonucleotide.

82 The metabolic instability of the glycosidic linkage in TCRB prompted us to synthesize the

83 ds a disaccharide that closely resembles the glycosidic linkage in the polylegionaminic acid from the

84 developed to confirm the presence of a beta-glycosidic linkage in the purified reaction product and

85 The construction of the 1,2-trans-glycosidic linkage in the terminal anthrose moiety was a

86 complementary specificities to hydrolyze the glycosidic linkages in agarose, a linear polymer compris

87 Glycoside hydrolases (GHs) cleave glycosidic linkages in carbohydrates, typically via inve

88 Cellulases hydrolyze beta-1,4 glycosidic linkages in cellulose, which are among the mo

89 rize anomeric configurations of newly formed glycosidic linkages in complex oligosaccharide synthesis

90 Cellobiohydrolases processively hydrolyze glycosidic linkages in individual polymer chains of cell

91 is a paradigm for the study of other unusual glycosidic linkages in model and parasitic organisms.

92 hich contains two of the most commonly found glycosidic linkages in N-linked oligosaccharides.

93 nd selective identification of alpha/beta1,2-glycosidic linkages in polysaccharides.

94 n and a reducing agent to oxidatively cleave glycosidic linkages in polysaccharides.

95 Challenging glycosidic linkages including alpha-gluco, beta-manno, a

96 ng as monoglucosylated oligosaccharides in N-glycosidic linkage interacted with the chaperone to the

97 The C-11' O-glycosidic linkage is highly unusual because it forms an

98 de thioglycosides containing 1,2-cis-2-amino glycosidic linkages is challenging.

99 The enzymatic hydrolysis of O-glycosidic linkages is one of the most diverse and wides

100 An immense variety of sugars and glycosidic linkages leads to an almost unlimited diversi

101 n-bond acceptor at the position ortho to the glycosidic linkage may not be required.

102 ygromycin B identified an orientation of one glycosidic linkage of hygromycin B consistent with metal

103 The glycosidic linkage of sialic acids is much more sensitiv

104 rate results in the cleavage of the beta-1,4 glycosidic linkage of the substrate chain and the unsatu

105 enzyme known to catalyse hydrolysis of the O-glycosidic linkages of ADP-ribose polymers, thereby reve

106 dase (GAA) cleaves the alpha1-4 and alpha1-6 glycosidic linkages of glycogen and related alpha-glucos

107 aride composed of partially acetylated 1-->4 glycosidic linkages of N-acetylgalactosamine and N-acety

108 the C1-O1 torsion angle (phi) comprising the glycosidic linkages of oligosaccharides.

109 The glycosidic linkages of the type 3 capsular polysaccharid

110 s ability to catalyze the hydrolysis of beta-glycosidic linkages once endocytosed, whereas equal conc

111 To prevent hydrolysis of acid-labile glycosidic linkages, optimal reaction conditions that ma

112 C-H protons is indicative of the position of glycosidic linkages or other substituents and can be rea

113 Moreover, glycans with unique glycosidic linkages, particularly from prokaryotes, whic

114 The glycosidic linkage positions are often determined by per

115 Glycosidic linkage preference originates from the minimi

116 e chemoselective introduction of a 1,2-trans glycosidic linkage prior to other linkages.

117 cture of the pentasaccharide complex found a glycosidic linkage psi torsion angle to be distorted by

118 dihedral angles has been determined for each glycosidic linkage relevant for the conformational prefe

119 fficient and stereoselective construction of glycosidic linkages remains one of the most formidable c

120 families acting on both axial and equatorial glycosidic linkages, respectively.

121 A review of its repertoire of glycosidic linkages suggests a minimum of 38 glycosyltra

122 sceptibility of the acid hydrolysis of alpha-glycosidic linkages than beta-glycosidic linkages.

123 re a measure of the amount of alpha- or beta-glycosidic linkages that are formed and a measure of the

124 ately 10(7) y),(5) of the 1-4 "head-to-tail" glycosidic linkages that join the common glucose polymer

125 The antibody recognizes O-GlcNAc in beta-O-glycosidic linkage to both serine and threonine.

126 is bound at the glycerol sn-3 position in O-glycosidic linkage to diacylglycerol, are abundant in pl

127 A direct glycosidic linkage to PG was also demonstrated for serot

128 ucin-type oligosaccharides is the beta 1-->3 glycosidic linkage to the core alpha-N-acetylgalactosami

129 gurations and of the (1 --> 4) and (1 --> 6) glycosidic linkages to the solution conformational entro

130 terized and revealed that in the complex the glycosidic linkage torsion angles between the two reduci

131 nc(II) alkoxide of acceptors establishes the glycosidic linkage under palladium catalysis to give ris

132 te alternating beta-(1-->5) and beta-(1-->6) glycosidic linkages using a single active site.

133 xtend this study to the synthesis of various glycosidic linkages using different sugar series.

134 trols stereoselective formation of 1,2-trans-glycosidic linkages via the arming participation effect.

135 ferases was performed, and the nature of the glycosidic linkages was determined by NMR.

136 om proton homonuclear coupling constants and glycosidic linkages were determined from 1H-13C heteronu

137 oic acid, with one of the hydroxyl groups in glycosidic linkage with glucuronic acid.

138 ortant glucoside containing multiple 1,2-cis-glycosidic linkages with complete anomeric control by us

139 ransferase in the GT41 family that creates N-glycosidic linkages with glucose and galactose at aspara

140 unction of the class of enzymes that cleaves glycosidic linkages with phosphate, the first mass spect

141 rocycles, melamine and barbituric acid, form glycosidic linkages with ribose and ribose-5-phosphate i

142 free energy landscapes obtained for the same glycosidic linkage within different oligosaccharides.

143 des information relating the location of the glycosidic linkage within the sequence of the glycan und

144 can show that the torsions of the different glycosidic linkages within the GPI tetrasaccharide can b