ライフサイエンスコーパス: glycosylphosphatidylinositol anchor

1 lacks a predicted transmembrane domain or a glycosylphosphatidylinositol anchor.

2 perfamily member with three Ig domains and a glycosylphosphatidylinositol anchor.

3 e, is attached to the parasite surface via a glycosylphosphatidylinositol anchor.

4 ransfection or spontaneous insertion via its glycosylphosphatidylinositol anchor.

5 -terminal peptide specifying attachment of a glycosylphosphatidylinositol anchor.

6 hich is attached to the plasma membrane by a glycosylphosphatidylinositol anchor.

7 express proteins linked to the membrane by a glycosylphosphatidylinositol anchor.

8 ransferase, is imbedded in the membrane by a glycosylphosphatidylinositol anchor.

9 r is linked to the plasma membrane only by a glycosylphosphatidylinositol anchor.

10 ke (LE) domains and a C' region containing a glycosylphosphatidylinositol anchor.

11 ts because it is attached to membranes via a glycosylphosphatidylinositol anchor.

12 of endogenous ephrinAs by cleavage of their glycosylphosphatidylinositol anchor.

13 NADases) that are linked to T lymphocytes by glycosylphosphatidylinositol anchors.

14 es against the cross-reacting determinant of glycosylphosphatidylinositol anchors.

15 , unlike the Yac-1 enzyme, appears not to be glycosylphosphatidylinositol-anchored.

16 eins, but we found evidence that they can be glycosylphosphatidylinositol-anchored.

17 ell-surface molecules, MAM domain-containing glycosylphosphatidylinositol anchor 1 (MDGA1) and 2 (MDG

18 ptor protein tyrosine phosphatase mu) domain glycosylphosphatidylinositol anchor 1 (MDGA1), a unique

19 ore mature myotubes primarily synthesize the glycosylphosphatidylinositol-anchored 130-kD isoform whi

20 ) expression of an aberrant form lacking the glycosylphosphatidylinositol anchor, 2) increased aggreg

21 sma membrane after enzymatic cleavage of its glycosylphosphatidylinositol anchor, a property that we

22 or by deletion of the C-terminal signal for glycosylphosphatidylinositol anchor addition.

23 e BiP C-terminal tetrapeptide (MDDL) and the glycosylphosphatidylinositol-anchor addition sequence of

24 Collectively, these studies indicate that glycosylphosphatidylinositol-anchored AGPs function to l

25 red for a late step of membrane fusion, as a glycosylphosphatidylinositol-anchored analogue of HA onl

26 finger proteins, is membrane-tethered with a glycosylphosphatidylinositol anchor and modulates the ac

27 ells, where it was previously shown that the glycosylphosphatidylinositol anchor and N-linked carbohy

28 le and from mouse lymphoma (Yac-1) cells are glycosylphosphatidylinositol-anchored and have similar e

29 orientation in the PM (transmembrane versus glycosylphosphatidylinositol-anchored), and ubiquitinati

30 ferences in the mechanisms by which soluble, glycosylphosphatidylinositol-anchored, and transmembrane

31 a mannose donor for protein N-glycosylation, glycosylphosphatidylinositol-anchoring, and C- and O-man

32 in or are attached to the cell membrane by a glycosylphosphatidylinositol anchor are expressed on bot

33 ART1 synthesized in Escherichia coli, glycosylphosphatidylinositol-anchored ART1 released with

34 of a huge bias in these organisms toward the glycosylphosphatidylinositol anchor as a mechanism for t

35 GPAA1 (glycosylphosphatidylinositol anchor attachment 1) is an

36 factor (DAF), which contains the signal for glycosylphosphatidylinositol anchor attachment.

37 chondrial structure and function, as well as glycosylphosphatidylinositol anchor biosynthesis.

38 inhibitors linked to the plasma membrane by glycosylphosphatidylinositol anchors, but not in the lev

39 n accelerated fusion rate when driven by the glycosylphosphatidylinositol-anchored, but not by the tr

40 a soluble N-terminal fragment (PrPN1) and a glycosylphosphatidylinositol-anchored C-terminal fragmen

41 completely alleviated down regulation of the glycosylphosphatidylinositol-anchored CD46 in Biken-CV-1

42 Fluorescently labeled glycosylphosphatidylinositol-anchored CD48 and CD58 were

43 raft-resident markers, ganglioside GM1, and glycosylphosphatidylinositol-anchored CD48.

44 d transient axonal glycoprotein-1 (TAG-1), a glycosylphosphatidylinositol-anchored cell adhesion mole

45 ADP-ribosyltransferase (ADPRT) is a glycosylphosphatidylinositol-anchored cell surface enzym

46 Glypicans are a family of glycosylphosphatidylinositol-anchored cell surface hepar

47 Prostate Stem Cell Antigen (PSCA) is a glycosylphosphatidylinositol-anchored cell surface prote

48 PHR1 and PHR2 encode putative glycosylphosphatidylinositol-anchored cell surface prote

49 l wall re-modeling by removal and release of glycosylphosphatidylinositol-anchored cell wall proteins

50 essor gene hyaluronidase 2 (HYAL2) encodes a glycosylphosphatidylinositol-anchored cell-surface prote

51 PSCA is a glycosylphosphatidylinositol-anchored cell-surface prote

52 Second, the glycosylphosphatidylinositol-anchored cell-surface prote

53 Here we demonstrate that glycosylphosphatidylinositol-anchored cell-surface recep

54 Glypican 3 (GPC3) is a family of glycosylphosphatidylinositol-anchored, cell-surface hepa

55 Glypican 3 (GPC3) belongs to a family of glycosylphosphatidylinositol-anchored, cell-surface hepa

56 hat, in agreement with its substitution by a glycosylphosphatidylinositol anchor, COB was polarly tar

57 ntified COBRA-LIKE2 (COBL2), a member of the glycosylphosphatidylinositol-anchored COBRA-LIKE gene fa

58 to APC-activated serum due to deficiency of glycosylphosphatidylinositol- anchored complement regula

59 lysis, and probably in Asn glycosylation and glycosylphosphatidylinositol anchor composition, exist b

60 to beta(1-->6)-glucan through a remnant of a glycosylphosphatidylinositol anchor containing five alph

61 Cells expressing glycosylphosphatidylinositol-anchored DAF but not the tr

62 The cells expressing glycosylphosphatidylinositol-anchored DAF contained a si

63 Glycosylphosphatidylinositol-anchored derivatives of sFR

64 brane and cytoplasmic domains of CD46 with a glycosylphosphatidylinositol anchor did not prevent cell

65 In contrast, for cells that express a glycosylphosphatidylinositol-anchored ectodomain of HA,

66 However, delivery of glycosylphosphatidylinositol-anchored endolyn was inhibi

67 was N-glycan independent, as was delivery of glycosylphosphatidylinositol-anchored endolyn.

68 GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell p

69 GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell p

70 drase IV (G267X CA IV) converts the normally glycosylphosphatidylinositol-anchored enzyme into a solu

71 ion, and showed that carbonic anhydrase 4, a glycosylphosphatidylinositol-anchored enzyme, functions

72 Because T-cadherin is a glycosylphosphatidylinositol-anchored extracellular prot

73 The glycosylphosphatidylinositol-anchored FcgammaRIIIb induc

74 Thus native CSP appears as a glycosylphosphatidylinositol-anchored, flexible rod-like

75 a subset of molecules that, like PrP, use a glycosylphosphatidylinositol anchor for membrane attachm

76 e molecule has two forms, an apically sorted glycosylphosphatidylinositol-anchored form and a basolat

77 dress this, we created a transmembrane and a glycosylphosphatidylinositol-anchored form of LPS-bindin

78 In contrast, YW3458, an inhibitor of glycosylphosphatidylinositol anchor formation, prevented

79 d to FK506-binding protein and clustering of glycosylphosphatidylinositol-anchored GFP at cell surfac

80 al through receptor tyrosine kinase TrkA and glycosylphosphatidylinositol-anchored glial cell-derived

81 GPIHBP1, a glycosylphosphatidylinositol-anchored glycoprotein of mi

82 ulticomplex receptor system in which CD14, a glycosylphosphatidylinositol-anchored glycoprotein, and

83 update on the structure of GPIHBP1, a 28-kDa glycosylphosphatidylinositol-anchored glycoprotein, and

84 llular prion protein (PrP(c)), a ubiquitous, glycosylphosphatidylinositol-anchored glycoprotein.

85 T binding proteins and we show that they are glycosylphosphatidylinositol-anchored glycoproteins in n

86 insoluble membrane vesicles, of two neuronal glycosylphosphatidylinositol-anchored (GPI) proteins: Th

87 rP) is a highly conserved, widely expressed, glycosylphosphatidylinositol-anchored (GPI-anchored) cel

88 Glypicans are a member of a family of glycosylphosphatidylinositol anchored heparan sulfate pr

89 cesses in nervous tissue, are ligands of the glycosylphosphatidylinositol-anchored heparan sulfate pr

90 ation in nervous tissue of glypican, a major glycosylphosphatidylinositol-anchored heparan sulfate pr

91 However, in vivo LPL is often complexed to glycosylphosphatidylinositol-anchored high density lipop

92 terstitial spaces; it then binds to GPIHBP1 (glycosylphosphatidylinositol-anchored high density lipop

93 Glycosylphosphatidylinositol-anchored high density lipop

94 e of either heparan sulfate proteoglycans or glycosylphosphatidylinositol-anchored high density lipop

95 Glycosylphosphatidylinositol-anchored high density lipop

96 To summarize recent data indicating that glycosylphosphatidylinositol-anchored high density lipop

97 nt new developments include the discovery of glycosylphosphatidylinositol-anchored high-density lipop

98 dulates lipoprotein metabolism by binding to glycosylphosphatidylinositol-anchored high-density lipop

99 lycerol-rich lipoproteins in the vicinity of glycosylphosphatidylinositol-anchored high-density lipop

100 Lateral mobility of the glycosylphosphatidylinositol-anchored HpHbR, and a appro

101 LY6E is a glycosylphosphatidylinositol-anchored, IFN-inducible pro

102 or its extracellular IgV domain linked to a glycosylphosphatidylinositol anchor-(IgV-GPI) enhanced l

103 are variants in MDGAs (MAM domain-containing glycosylphosphatidylinositol anchors), including multipl

104 Glycosylphosphatidylinositol-anchored influenza hemagglu

105 contrast, BiPN fusion proteins containing a glycosylphosphatidylinositol anchor instead of the ISG65

106 Membrane attachment via a C-terminal glycosylphosphatidylinositol anchor is critical for conv

107 ly restores fertility to ms1d, and encodes a glycosylphosphatidylinositol-anchored lipid transfer pro

108 matrix metalloproteinase (MMP) (MMP25) is a glycosylphosphatidylinositol-anchored matrix metalloprot

109 MMP25 (MT6-MMP) is one of the two glycosylphosphatidylinositol-anchored matrix metalloprot

110 CD160, a glycosylphosphatidylinositol-anchored member of the immu

111 Here we show that DRAGON, a glycosylphosphatidylinositol-anchored member of the repu

112 Carboxypeptidase M, a glycosylphosphatidylinositol-anchored membrane glycoprot

113 CD59 is a glycosylphosphatidylinositol-anchored membrane glycoprot

114 Decay-accelerating factor ([DAF] CD55) is a glycosylphosphatidylinositol-anchored membrane inhibitor

115 Like LPS, sPGN and LTA bind to the glycosylphosphatidylinositol-anchored membrane protein C

116 a protein called LPS-binding protein and the glycosylphosphatidylinositol-anchored membrane protein C

117 Decay-accelerating factor (DAF, CD55) is a glycosylphosphatidylinositol-anchored membrane protein t

118 Decay-accelerating factor (DAF) is a glycosylphosphatidylinositol-anchored membrane protein t

119 While PrPC is principally a glycosylphosphatidylinositol-anchored membrane protein,

120 that LORELEI (LRE), which encodes a putative glycosylphosphatidylinositol-anchored membrane protein,

121 cay-accelerating factor (DAF) and CD59 are 2 glycosylphosphatidylinositol-anchored membrane proteins

122 n in the PIGA gene leads to membrane loss of glycosylphosphatidylinositol-anchored membrane proteins,

123 nsmembrane serine protease, and prostasin, a glycosylphosphatidylinositol-anchored membrane serine pr

124 ht the common and distinct properties of the glycosylphosphatidylinositol-anchored membrane type-matr

125 creted collagenases MMP-1 and MMP-13 and the glycosylphosphatidylinositol-anchored membrane-type MMPs

126 We have identified CD48, a glycosylphosphatidylinositol-anchored molecule, to be th

127 Members of the IgLON family of glycosylphosphatidylinositol-anchored neural cell adhesi

128 Glycosylphosphatidylinositol-anchored neurotoxin-like re

129 ix metalloproteinase (leukolysin/MT6-MMP), a glycosylphosphatidylinositol-anchored neutrophil matrix

130 t axon regeneration in vitro and bind to the glycosylphosphatidylinositol-anchored Nogo receptor (NgR

131 ts identify gangliosides (GD1a and GT1b) and glycosylphosphatidylinositol-anchored Nogo receptors (Ng

132 The role of extracellular domains and the glycosylphosphatidylinositol anchor of DAF in the proces

133 Replacing the glycosylphosphatidylinositol anchor of DAF with the tran

134 her associated with cell membranes through a glycosylphosphatidylinositol anchor or released as a sol

135 Proteins having glycosylphosphatidylinositol anchors or single transmemb

136 ific phospholipase C (PI-PLC), which cleaves glycosylphosphatidylinositol anchors, or by NEP1-40, a p

137 9167), glutathione metabolism (P = 0.01281), glycosylphosphatidylinositol anchor (P = 0.01949), adher

138 Furthermore, engineered CEACAMs appended to glycosylphosphatidylinositol anchors partitioned with TX

139 A double mutant with pmr6 (defective in a glycosylphosphatidylinositol-anchored pectate lyase-like

140 luciferase, adsorbed to antibodies against a glycosylphosphatidylinositol-anchored plasma membrane pr

141 report that the female gametophyte-expressed glycosylphosphatidylinositol-anchored protein (GPI-AP) L

142 stribution of a crosslinked or uncrosslinked glycosylphosphatidylinositol-anchored protein (the folat

143 We show that LYSIN MOTIF DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED PROTEIN 2 (LYM2),

144 using cyan/yellow fluorescent protein-tagged glycosylphosphatidylinositol-anchored protein and vesicu

145 cholesterol analog, dehydroergosterol, and a glycosylphosphatidylinositol-anchored protein are largel

146 al PM area by the addition of membrane via a glycosylphosphatidylinositol-anchored protein compartmen

147 homology to Saccharomyces cerevisiae GAS1, a glycosylphosphatidylinositol-anchored protein essential

148 CD14 is a glycosylphosphatidylinositol-anchored protein expressed

149 erived neurotrophic factor family, binds the glycosylphosphatidylinositol-anchored protein GFRalpha3

150 l surface marker for human fetal liver HSCs, glycosylphosphatidylinositol-anchored protein GPI-80, th

151 a secretory, cytoplasmic, transmembrane, or glycosylphosphatidylinositol-anchored protein in T. cruz

152 The cDNA sequence predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 ami

153 GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capilla

154 CD14, a glycosylphosphatidylinositol-anchored protein on the sur

155 PLAP (glycosylphosphatidylinositol-anchored protein placental

156 CD59 is a glycosylphosphatidylinositol-anchored protein that inhib

157 monstrate that neogenin may stabilize HJV, a glycosylphosphatidylinositol-anchored protein that inter

158 n the UMOD gene, which encodes Uromodulin, a glycosylphosphatidylinositol-anchored protein that is ex

159 er/sleepless (qvr/sss) gene encodes a small, glycosylphosphatidylinositol-anchored protein that plays

160 D59 is a ubiquitously expressed cell-surface glycosylphosphatidylinositol-anchored protein that prote

161 of reactive lysis (MIRL, CD59) is an 18-kDa glycosylphosphatidylinositol-anchored protein that regul

162 We observed that Golgi, lysosomes, and glycosylphosphatidylinositol-anchored protein vesicles a

163 d Golgi exocytosis but not the exocytosis of glycosylphosphatidylinositol-anchored protein vesicles o

164 tly less time in TCZs compared with Thy-1, a glycosylphosphatidylinositol-anchored protein, and GM1,

165 sis that a lynx family member, or indeed any glycosylphosphatidylinositol-anchored protein, could act

166 ion behavior of urokinase receptor (uPAR), a glycosylphosphatidylinositol-anchored protein, in a plan

167 hy profile strongly suggested that Shu1 is a glycosylphosphatidylinositol-anchored protein.

168 The sleepless gene encodes a brain-enriched, glycosylphosphatidylinositol-anchored protein.

169 rnal hemoglobinuria (PNH) with antibodies to glycosylphosphatidylinositol-anchored proteins (anti-CD5

170 Both are predicted glycosylphosphatidylinositol-anchored proteins (GPI-APs)

171 nt-mediated hemolysis due to deficiencies of glycosylphosphatidylinositol-anchored proteins (GPI-APs)

172 Most glycosylphosphatidylinositol-anchored proteins (GPI-APs)

173 n of cholesterol-rich membranes that contain glycosylphosphatidylinositol-anchored proteins (GPI-APs)

174 brane of cells that are highly enriched with glycosylphosphatidylinositol-anchored proteins and chole

175 king transmembrane or intracellular domains, glycosylphosphatidylinositol-anchored proteins can modul

176 pacity is saturated during stress, misfolded glycosylphosphatidylinositol-anchored proteins dissociat

177 Loss of glycosylphosphatidylinositol-anchored proteins had no ef

178 buoyant microdomains including those rich in glycosylphosphatidylinositol-anchored proteins has been

179 a role for heparan sulfate proteoglycans and glycosylphosphatidylinositol-anchored proteins in axon g

180 that the defective surface expression of the glycosylphosphatidylinositol-anchored proteins is caused

181 versibly impaired the PD localization of the glycosylphosphatidylinositol-anchored proteins Plasmodes

182 SAG1, these new SRS genes encode apparently glycosylphosphatidylinositol-anchored proteins that shar

183 cosaminoglycans, glycoproteins, glycolipids, glycosylphosphatidylinositol-anchored proteins) and the

184 embrane that is highly enriched in caveolin, glycosylphosphatidylinositol-anchored proteins, and sign

185 Alkaline phosphatase, as well as five other glycosylphosphatidylinositol-anchored proteins, and tran

186 oxide synthase) and are markedly depleted in glycosylphosphatidylinositol-anchored proteins, beta-act

187 d in Chinese hamster ovary-K1 fibroblasts as glycosylphosphatidylinositol-anchored proteins, both cou

188 Yet how nonubiquitinated proteins, such as glycosylphosphatidylinositol-anchored proteins, enter MV

189 Glycosylphosphatidylinositol-anchored proteins, GPI-prot

190 The folate receptor, like many glycosylphosphatidylinositol-anchored proteins, is found

191 The mode of internalization of glycosylphosphatidylinositol-anchored proteins, lacking

192 ggesting that raft assembly does not require glycosylphosphatidylinositol-anchored proteins, raft pro

193 They included eight glycosylphosphatidylinositol-anchored proteins, several

194 oxysmal nocturnal hemoglobinuria, which lack glycosylphosphatidylinositol-anchored proteins, show sig

195 monocytogenes ortholog, had high activity on glycosylphosphatidylinositol-anchored proteins.

196 not require heparan sulfate proteoglycan- or glycosylphosphatidylinositol-anchored proteins.

197 sting of 12 members, all predicted to encode glycosylphosphatidylinositol-anchored proteins.

198 enriched in cholesterol, sphingolipids, and glycosylphosphatidylinositol-anchored proteins.

199 n with other cell surface proteins including glycosylphosphatidylinositol-anchored proteins.

200 gi apparatus and as the lipid moiety in many glycosylphosphatidylinositol-anchored proteins.

201 g lipid mixtures is also applicable to other glycosylphosphatidylinositol-anchored proteins.

202 pid rates of endocytosis and lateral flow of glycosylphosphatidylinositol-anchored proteins.

203 In contrast, cells transfected with the glycosylphosphatidylinositol-anchored proteoglycan glypi

204 for identification of the myristoylated and glycosylphosphatidylinositol-anchored proteome with sele

205 Mammalian prions refold host glycosylphosphatidylinositol-anchored PrP(C) into beta-s

206 Consistent with the presence of a glycosylphosphatidylinositol anchor, pypAg-2 fractionate

207 nase-type plasminogen activator (uPA) to its glycosylphosphatidylinositol-anchored receptor (uPAR) in

208 Previously, a high affinity, glycosylphosphatidylinositol-anchored receptor for folat

209 id cells to LPS are mediated through CD14, a glycosylphosphatidylinositol-anchored receptor that bind

210 eptor with a truncated death domain, DcR1, a glycosylphosphatidylinositol-anchored receptor, and OPG

211 ctivator (uPA) binds to cells via a specific glycosylphosphatidylinositol-anchored receptor.

212 Recently, we identified the glycosylphosphatidylinositol-anchored repulsive guidance

213 lipoprotein lipase minigene construct with a glycosylphosphatidylinositol anchoring sequence on the c

214 Here we showed that testisin, a glycosylphosphatidylinositol-anchored serine protease, c

215 In skin, matriptase acts upstream of the glycosylphosphatidylinositol-anchored serine protease, p

216 mediated via its activation of prostasin, a glycosylphosphatidylinositol-anchored serine protease.

217 terminal tags (FLAG-His6) replace the native glycosylphosphatidylinositol anchor signal sequences.

218 lta-1 constructs truncated at their putative glycosylphosphatidylinositol anchor site, located before

219 sive O glycosylation, followed by a putative glycosylphosphatidylinositol anchor site.

220 ceptors that contain a common ligand-binding glycosylphosphatidylinositol-anchored subunit termed the

221 t of HJV, hemojuvelin, contains a C-terminal glycosylphosphatidylinositol anchor, suggesting that it

222 (PrP) is usually attached to membranes by a glycosylphosphatidylinositol-anchor that associates with

223 hat form chitin, N-linked glycosylation, and glycosylphosphatidylinositol anchors, the mutant phenoty

224 Because uPAR is glycosylphosphatidylinositol-anchored, the signaling rec

225 ular prion protein, PrP(C), is attached by a glycosylphosphatidylinositol anchor to the outer leaflet

226 in is a trypsin-like serine protease that is glycosylphosphatidylinositol-anchored to the epithelial

227 PrPC is tethered to the plasma membrane by a glycosylphosphatidylinositol anchor, topological variant

228 binding to uPA receptor (uPAR/CD87), but how glycosylphosphatidylinositol-anchored uPAR mediates sign

229 pe tissue plasminogen activator (TPA) or for glycosylphosphatidylinositol-anchored urokinase-type pla

230 uthentic, secreted form of brevican, not the glycosylphosphatidylinositol-anchored variant, is the pr

231 itol-specific phospholipase C, showing it is glycosylphosphatidylinositol-anchored, whereas apical ca

232 coli and demonstrate the significance of the glycosylphosphatidylinositol anchor, which determines th

233 rting and trafficking of proteins containing glycosylphosphatidylinositol anchors with cells.

234 in the form of water-soluble domain lacking glycosylphosphatidylinositol anchor (ws-LYNX1;) revealed