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1 l diacylglycerol synthesized by a processive glycosyltransferase.
2 by cellulose synthase, a processive family-2 glycosyltransferase.
3 ucleotide-activated form, acting as a Leloir glycosyltransferase.
4 nes encodes a protein that is likely to be a glycosyltransferase.
5 perty not previously described for any other glycosyltransferase.
6 a systemic supply of FKRP protein acting as glycosyltransferase.
7 ransferase domain and a predicted C-terminal glycosyltransferase.
8 d serine-rich repeat adhesins by a series of glycosyltransferases.
9 process regulated by the availability of key glycosyltransferases.
10 ntrasted with common properties of canonical glycosyltransferases.
11 to the cell membrane and is hence exposed to glycosyltransferases.
12 endogenous nucleotide sugar transporters and glycosyltransferases.
13 nto LacNAc and then elaborated by a panel of glycosyltransferases.
14 s, whose interactions can be tuned by Fringe glycosyltransferases.
15 cy of IgA1 via coordinated modulation of key glycosyltransferases.
16 new mechanistic insight into this family of glycosyltransferases.
17 ns of functionally distinct glycosidases and glycosyltransferases.
18 anisms responsible for Golgi localization of glycosyltransferases.
19 novel feature not observed before for lipid glycosyltransferases.
20 mmalian expression vectors encoding specific glycosyltransferases.
21 tion of sequentially acting glycosidases and glycosyltransferases.
22 T/JBP, pyrimidine hydroxymethylases, Mom and glycosyltransferases.
23 cture even in the presence of the other five glycosyltransferases.
24 sting that they are synthesized by retaining glycosyltransferases.
25 diverse range of substrates required for the glycosyltransferases.
26 the nucleotide-sugar substrates required by glycosyltransferases.
27 separately from related Golgi-resident GT32 glycosyltransferases.
28 hat CgT represents a new member of GT-A-type glycosyltransferases.
29 s then extended to up to 11 HMOs by 4 robust glycosyltransferases.
30 by virtue of the inherent specificity of the glycosyltransferases.
31 amine (UDP-GlcNAc), a substrate for cellular glycosyltransferases.
32 inds the sugar nucleotide UDP-glucose, as do glycosyltransferases.
33 ouse model was generated to excise exostosin glycosyltransferase 1 (Ext1) in keratin 14-positive cell
34 dentified a unique hybrid protein dGT1 (dual glycosyltransferase 1) that contains two distinct domain
36 yzed by the integral membrane lipid-to-lipid glycosyltransferase 4-amino-4-deoxy-L-arabinose transfer
37 18 from SW1990 cells increased levels of UDP-glycosyltransferase 8 and miR-218 was found to bind to i
39 ped FKRP might circulate as an extracellular glycosyltransferase, able to exert a "glycan remodelling
40 at such that the cleavage region lies in the glycosyltransferase active site above uridine diphosphat
41 ure of a previously disordered region in the glycosyltransferase active site and discuss its implicat
43 d have widespread and significant impacts on glycosyltransferase activities and would be responsible
44 oreover, so far unknown chitin hydrolase and glycosyltransferase activities were detected using GlcNA
50 tein-protein interaction and crucial for the glycosyltransferase activity of CgT in vitro and in vivo
51 l number of enzyme activities comprising the glycosyltransferase activity of class A PBP1b and the D,
52 rate Srr2-GlcNAc, concurrently abolished the glycosyltransferase activity of GtfC, and also altered g
58 njugates that takes advantage of recombinant glycosyltransferases and a corresponding sugar nucleotid
61 ately related to the spatial distribution of glycosyltransferases and glycosyl hydrolases within the
62 nzymatic labeling (or SEEL) uses recombinant glycosyltransferases and nucleotide-sugar analogues to a
63 neer glycans using different permutations of glycosyltransferases and to investigate biosynthetic pat
64 such as the kinetoplastid J-base generating glycosyltransferase (and its homolog GREB1), the catalyt
65 PG synthase with glycan chain polymerizing (glycosyltransferase) and peptide cross-linking (transpep
66 iver is the most noted among the circulatory glycosyltransferases, and decorates marrow hematopoietic
67 ent signaling pathways regulated by O-GlcNAc glycosyltransferase are thus fundamental for T cell biol
69 g target for control of the pathogen, as the glycosyltransferases are absent from mammalian hosts.
72 y ligation assay, we found that all examined glycosyltransferases are in the vicinity of these UDP-su
74 genetic analyses, we found that Caulobacter glycosyltransferases are primarily redundant but that Pb
77 neer glycans using different permutations of glycosyltransferases as well as to investigate biosynthe
82 in the center of the plant secondary product glycosyltransferase box (A389V) reduced the enzymatic ac
83 gle amino acid changes in cps genes encoding glycosyltransferases can alter substrate specificities,
84 ts a convenient strategy to rapidly optimize glycosyltransferase catalysts for the synthesis of compl
86 integration of the general reversibility of glycosyltransferase-catalyzed reactions, artificial glyc
88 that they both belong to the branch-forming glycosyltransferase cluster, but are distantly related a
89 we examined the functions of three capsular glycosyltransferases (Cps2F, Cps2G, and Cps2I) involved
91 ly required for induction of Fut7 and Gcnt1, glycosyltransferases critical for selectin ligand biosyn
92 mal and pathological conditions, but several glycosyltransferase-deficient mice exhibit no or only mi
93 cdB-L543A, delayed toxicity in mice, whereas glycosyltransferase-deficient TcdB demonstrated no toxic
95 llographic model for inhibition of the PBP1b glycosyltransferase domain by the potent substrate analo
98 proteolytic fragment containing the putative glycosyltransferase domain was tested in isolation for a
99 mer in which each blade contains a GT-B-type glycosyltransferase domain with a typical Rossmann fold.
100 The csaA gene product contains a predicted glycosyltransferase domain with structural homology to G
103 we propose the linkage specificities of the glycosyltransferase domains are conserved in KpsC homolo
105 rases (ppGalNAc-Ts) on catalytic activity of glycosyltransferases during O-GalNAc glycan biosynthesis
106 n vivo glycoengineering technologies and the glycosyltransferase-enabled in vitro engineering method,
107 pids are synthesized by a single promiscuous glycosyltransferase encoded by the ORF atu2297, with UDP
108 of Xoc flagellin was altered by deletion of glycosyltransferase-encoding rbfC, but this had little e
109 or is regulated in part by the repertoire of glycosyltransferase enzymes (which make the glycan ligan
110 beta-Kdo counterparts were not identified as glycosyltransferase enzymes by bioinformatics tools and
113 ypoxia, suggesting that hypoxia up-regulates glycosyltransferase expression required for F77 antigen
115 epresented among the 98 currently recognized glycosyltransferase families in the Carbohydrate-Active
117 gene, At3g57630, in clade E of the inverting Glycosyltransferase family GT47 as a candidate for the t
118 e of the adaptation by trypanosomes of beta3-glycosyltransferase family members to catalyze beta1-2 g
119 ests that the parasite has adapted the beta3-glycosyltransferase family to catalyze beta1-2 linkages.
120 hat TbGT15, another member of the same beta3-glycosyltransferase family, encodes an equally divergent
121 ted C-terminal GT-B domain and defines a new glycosyltransferase family, GT97, in CAZy (Carbohydrate-
125 IBP was first catalyzed by P450, and then by glycosyltransferase, followed by further storage or meta
126 rimetric screen to enable the engineering of glycosyltransferases for combinatorial sugar nucleotide
127 ngs to a large family of membrane-associated glycosyltransferases for which the understanding of the
128 how that due to the asymmetric effect of the glycosyltransferase Fringe, different outcomes are gener
129 found that Toxoplasma utilizes a cytoplasmic glycosyltransferase from an ancient clade of CAZy family
130 tidine monophosphate-Kdo-dependent alpha-Kdo glycosyltransferase from LPS assembly is well characteri
135 ene, a lipB (kpsS)-like gene, and a putative glycosyltransferase gene designated csaA (capsule synthe
136 ant (DeltaepsE) lacking the putative priming glycosyltransferase gene located within a predicted eps
138 agellin glycosylation, including a predicted glycosyltransferase gene that is linked to the flagellin
140 P716Y1 with oxidosqualene cyclase, P450, and glycosyltransferase genes available from other plant spe
141 I (TbGnTI) among a set of putative T. brucei glycosyltransferase genes belonging to the beta3-glycosy
143 an biosynthesis in mycobacteria involves two glycosyltransferases, GlfT1 and GlfT2, which have been t
144 ormation of this polymer is catalyzed by the glycosyltransferase GlfT2, a processive carbohydrate pol
145 tribution of processing machineries, such as glycosyltransferases, glycosidases, and nucleotide sugar
146 s created by the collaborative activities of glycosyltransferases, glycosidases, nucleotide-sugar tra
148 discovered that the gene Mgat3 encoding the glycosyltransferase GnT-III is elevated in epithelial ov
149 ified by five sugars via the action of three glycosyltransferases, Gnt1, PgtA, and AgtA, which are re
151 re members of the carbohydrate-active enzyme glycosyltransferase (GT) 31 family (CAZy GT31) involved
154 rstood, largely because of the resistance of glycosyltransferase (GT) enzymes to structural character
158 mannosyltransferase A (PimA) is an essential glycosyltransferase (GT) that initiates the biosynthetic
159 e EpsHIJK proteins suggest EpsH and EpsJ are glycosyltransferases (GT) with a GT-A fold; EpsI is a GT
161 lyzed the mechanism by which the cytosolic O-glycosyltransferase GtfA/B of Streptococcus gordonii mod
162 own previously that gtfA and gtfB encode two glycosyltransferases, GtfA and GtfB, that catalyze the t
163 O-antigen can be modified by the activity of glycosyltransferase (gtr) operons acquired by horizontal
166 zymes such as glycoside hydrolases (GHs) and glycosyltransferases (GTs) are of growing importance as
167 al MUCILAGE-RELATED (MUCI) genes that encode glycosyltransferases (GTs) involved in the production of
168 c analysis identified six main proteins: two glycosyltransferases (GTs) TaGT43-4 and TaGT47-13; two p
171 the first time that a Michaelis complex of a glycosyltransferase has been described, and it clearly s
173 their organizational interplay and show that glycosyltransferase homomers are assembled in the endopl
174 is predicted to possess a typical GT-A-type glycosyltransferase, however, the activity remains unkno
175 ion of a dual specificity cis-AB blood group glycosyltransferase in complex with a synthetic UDP-GalN
177 nd instead promotes the phosphorylation of a glycosyltransferase in the biosynthetic pathway, thereby
179 understanding of the function of glycan and glycosyltransferase in the tumorigenesis, progression an
181 Predictions for the function of two UDP-glycosyltransferases in flavonoid metabolism were confir
183 l processes mediated by 2 distinct groups of glycosyltransferases in oral streptococci that are impor
185 sugars, which serve as donor substrates for glycosyltransferases in the lumen of Golgi vesicles and
186 rcially available and recombinantly produced glycosyltransferases including key N-acetylglucosaminylt
187 creased abundance of transcripts for several glycosyltransferases indicated the enzymes that may be i
189 RG-II in cell elongation and the utility of glycosyltransferase inhibitors as new tools for studying
190 udy, we show that using moenomycin and other glycosyltransferase inhibitors as templates, we were abl
192 ations affecting exostosin-like 3 (EXTL3), a glycosyltransferase involved in heparan sulfate (HS) bio
193 e genes identified was lpsB, which encodes a glycosyltransferase involved in lipopolysaccharide (LPS)
194 nt with the predicted functions of the WbkD (glycosyltransferase involved in the biosynthesis of the
195 R XYLEM9-LIKE [IRX9L]) encodes a family GT43 glycosyltransferase involved in xylan backbone biosynthe
197 fold of ppGalNAc-Ts in enzymatic activity of glycosyltransferases involved in the O-glycan biosynthes
198 role in the process; thus understanding the glycosyltransferases involved is key to identifying new
199 role in the process, thus understanding the glycosyltransferases involved is key to identifying new
202 and dependent on the expression of both like-glycosyltransferase (LARGE) and partially functional FKR
203 HepII) are controlled by phase-variable LOS glycosyltransferase (lgt) genes; we sought to define how
205 this binding requires Mg(2+) Mutation of the glycosyltransferase-like metal ion binding motif in H3 g
206 synthesis, while UPEX1 encodes a family GT31 glycosyltransferase likely involved in galactosylation o
207 dentified colonization genes, epaX encodes a glycosyltransferase located in a variable region of the
208 Thus, bryophytes and algae likely lack the glycosyltransferase machinery required to synthesize api
210 y studies have suggested the significance of glycosyltransferase-mediated macromolecule glycosylation
211 ontaining multiple cellulose synthase (CESA) glycosyltransferases mediates cellulose microfibril form
212 ing transcription factors, cytochrome P450s, glycosyltransferases, methyltransferases and transporter
213 on between nucleotide sugar transporters and glycosyltransferases might be a more common phenomenon t
217 nt fibroblasts, while microarray analysis of glycosyltransferase mRNAs detected modestly increased ex
218 nd LAM molecules produced by three different glycosyltransferase mutants of Mycobacterium smegmatis w
220 the cytoplasm and is mediated by a soluble N-glycosyltransferase (NGT) that uses nucleotide-activated
224 uences is cleaved by the nutrient-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-Glc
227 ar mechanism of the toxin component Afp18 as glycosyltransferase opens new perspectives in studies of
229 example, Caulobacter crescentus encodes six glycosyltransferase paralogs of largely unknown function
230 T-IV, and GnT-V in cells revealed that these glycosyltransferases, particularly GnT-IV, play importan
231 previously shown that loss of a conserved O-glycosyltransferase (PGANT4) in Drosophila results in ab
232 These synthetic enzymes each possess a PG glycosyltransferase (PGT) domain and a transpeptidase (T
233 ers to the pathway in which Protein N- and O-glycosyltransferases (PGTases) sequentially add monosacc
234 mpounds that bind to bacterial peptidoglycan glycosyltransferases (PGTs) and inhibit cell wall biosyn
235 that perform these reactions, polyisoprenyl-glycosyltransferases (PI-GTs) include dolichol phosphate
237 t, mice double heterozygous for Jag1 and the glycosyltransferase, Poglut1 (Rumi), start showing a sig
238 l interaction between GOLPH3 and a mammalian glycosyltransferase, POMGnT1, which is involved in the O
239 n display unexpected promiscuity, with human glycosyltransferase pp-alpha-GanT2 able to utilize both
240 saminyltransferase (LARGE) is a bifunctional glycosyltransferase previously shown to hyperglycosylate
247 anscribed with SMU.2067, encoding a putative glycosyltransferase referred to here as PgfS (protein gl
248 h the physiological function of blood stream glycosyltransferases remains unclear, they are likely re
249 cell surface glycans where remotely produced glycosyltransferases remodel surfaces of target cells an
250 transferase 1 gene (Pofut1), which encodes a glycosyltransferase required for NotchR-mediated cell-ce
257 reatly increased in CSCs; (ii) among various glycosyltransferases tested, mRNA levels for ST3GAL5, B4
260 deletion of bshA (sa1291), which encodes the glycosyltransferase that catalyzes the first step of BSH
261 thin a GBS-specific gene encoding a putative glycosyltransferase that confers resistance to HMOs, sug
264 mannosyltransferase A (PimA) is an essential glycosyltransferase that initiates the biosynthetic path
265 cNAc transferase (OGT) is a serine/threonine glycosyltransferase that is essential for development an
266 demonstrated that lymphostatin is a putative glycosyltransferase that is important in intestinal colo
269 l, deeply conserved family of plant-specific glycosyltransferases that add arabinose sugars to divers
270 hway nor the roles of many known or putative glycosyltransferases that are essential for this process
271 mediators in vivo by engineering solubilized glycosyltransferases that attach galactose or sialic aci
272 ted organizational interplay between Golgi N-glycosyltransferases that involves dynamic and organelle
273 ically relevant substrates of small-molecule glycosyltransferases that often show broad sugar accepto
274 esized by membrane-integrated and processive glycosyltransferases that polymerize UDP-activated gluco
276 Quantitative PCR gene expression studies of glycosyltransferases that regulate display of sLe(X) rev
277 model, we highlight new features of several glycosyltransferases that sequentially modify the serine
278 motile DeltahpsE-G strain, which lacks three glycosyltransferases that synthesize hormogonium polysac
279 n to chaperones or other known regulators of glycosyltransferases, the ENPP3-mediated hydrolysis of n
281 Thus, DUF1792 represents a new family of glycosyltransferases; therefore, we designate it as a GT
282 is study reports the discovery of a second S-glycosyltransferase, ThuS, and shows that ThuS catalyzes
283 d compounds could be selectively extended by glycosyltransferases to give libraries of asymmetrical m
284 ic strategy, using a limited number of human glycosyltransferases, to access a collection of 60 asymm
285 e detected; however, activities of the other glycosyltransferases together with bioinformatic analyse
286 N-terminal DUF1792 is a novel GT-D-type glycosyltransferase, transferring Glc residues to Glc-Gl
287 s study, we determine that CgT is a distinct glycosyltransferase, transferring GlcNAc residues to Glc
288 cluding a phage protein and a phase-variable glycosyltransferase ubiquitous among the diverse set of
291 ed to involve a family 1 UDP-sugar dependent glycosyltransferase (UGT) to facilitate acetophenone acc
292 th similarity to terpene URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASES (UGTs) from Arabidopsis (Arabidopsi
294 uding cytochrome P450 monooxygenases and UDP-glycosyltransferases, was shared between both treatments
296 candidate gene in this region encodes a GT61 glycosyltransferase, which has been implicated in arabin
297 ntibiotic moenomycin that inhibits bacterial glycosyltransferases, which are essential for peptidogly
298 I pilins are O-glycosylated through the TfpO glycosyltransferase with a single subunit of O-antigen (
299 arge clostridial toxins, which are retaining glycosyltransferases with a DXD motif involved in bindin
300 ted a family of putative UDP-sugar-dependent glycosyltransferases with similarity to the mammalian be
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