ライフサイエンスコーパス: glycyl-tRNA

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1 Glycyl tRNA synthetase (GlyRS) provides a unique case am

2 t point mutations in the gene GARS, encoding glycyl tRNA synthetase (GlyRS).

3 disease-associated missense mutations in the glycyl tRNA synthetase gene in families with CMT2D and d

4 itochondrial forms of Caenorhabditis elegans glycyl-tRNA synthetase (CeGlyRS) are encoded by the same

5 ly implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and

6 a unique disease caused by mutations in the glycyl-tRNA synthetase (GARS) gene.

7 throughout the primary sequence of the human glycyl-tRNA synthetase (GARS).

8 a Drosophila model for CMT with mutations in glycyl-tRNA synthetase (GARS).

9 axonal neuropathy, is caused by mutations in glycyl-tRNA synthetase (GARS).

10 ctions may explain why dominant mutations in glycyl-tRNA synthetase (GlyRS) and tyrosyl-tRNA syntheta

11 res and biochemical analyses show that human glycyl-tRNA synthetase (GlyRS) produces Ap4A by direct c

12 Here we focus on mutations in glycyl-tRNA synthetase (GlyRS) that cause an axonal form

13 e gene GARS, encoding the ubiquitous enzyme, glycyl-tRNA synthetase (GlyRS), cause peripheral nerve d

14 in the housekeeping gene GARS, which encodes glycyl-tRNA synthetase (GlyRS), mediate selective periph

15 cerevisiae, two genes (GRS1 and GRS2) encode glycyl-tRNA synthetase (GlyRS1 and GlyRS2, respectively)

16 SR1 glycyl-tRNA synthetase acylates tRNA(Gly)UCA with glycin

17 Pol gamma B shows high similarity to glycyl-tRNA synthetase and dimerizes through an unusual

18 Coexpression of SR1 glycyl-tRNA synthetase and tRNA(Gly)UCA in Escherichia c

19 h a significant conformational transition in glycyl-tRNA synthetase coupled to the binding of GSAd.

20 of horizontal transfer of the gene encoding glycyl-tRNA synthetase from a bacterium of the Thermus-D

21 by the expression of the only known gene for glycyl-tRNA synthetase in Schizosaccharomyces pombe.

22 Unfolding of glycyl-tRNA synthetase is complex with a native state, a

23 erential scanning calorimetry indicated that glycyl-tRNA synthetase is stabilized by nucleotides.

24 Thus, a single gene for glycyl-tRNA synthetase likely encodes both cytoplasmic a

25 ATP and nonsubstrate ATP analogues render glycyl-tRNA synthetase more resistant to digestion by a

26 Unfolding of Bombyx mori glycyl-tRNA synthetase was examined by multiple spectros

27 The interaction of adenine nucleotides with glycyl-tRNA synthetase was examined by several experimen

28 f the Bacillus subtilis glyQS gene (encoding glycyl-tRNA synthetase) can be reproduced in a purified

29 fferent mutant alleles of GARS (the gene for glycyl-tRNA synthetase) have been reported to cause a do

30 mutation in Aats-gly (also known as gars or glycyl-tRNA synthetase), the Drosophila melanogaster ort

31 f the Bacillus subtilis glyQS gene, encoding glycyl-tRNA synthetase, depends on stabilization of an a

32 GARS encodes glycyl-tRNA synthetase, the enzyme that couples glycine

33 AMPPNP and AMPPCP were not substrates for glycyl-tRNA synthetase.

34 ied as GRS1, which encodes the S. cerevisiae glycyl-tRNA synthetase.

35 Interestingly, significant homology to glycyl-tRNA synthetases from prokaryotic organisms revea

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