ライフサイエンスコーパス: gonad

1 diting via Oviductal Nucleic Acids Delivery (GONAD).

2 ed germ cell abnormalities in the C. elegans gonad.

3 patterning within the Caenorhabditis elegans gonad.

4 nd enabled their subsequent removal from the gonad.

5 t to specify male cell identity in the mouse gonad.

6 ergo a long-range migration to the embryonic gonad.

7 can be faithfully replicated outside of the gonad.

8 for lnkn-1-like function in C. elegans male gonad.

9 migration in the developing C. elegans male gonad.

10 ellular bridge in the Caenorhabditis elegans gonad.

11 ormal differentiation in the Drosophila male gonad.

12 rom germ cells to meiocytes in the mammalian gonad.

13 y arrived primordial germ cells in the E10.5 gonad.

14 a subset of pre-meiotic oogonia in the adult gonad.

15 generation of testicular cords in the fetal gonad.

16 ng longevity in response to signals from the gonad.

17 nt as well as the function of the adult male gonad.

18 sonephros that induces Stra8 in the adjacent gonad.

19 line stem cell progenitors in the C. elegans gonad.

20 l self-fertilization in a mixed ovary/testis gonad.

21 channel diameter and dynamics throughout the gonad.

22 ASH protein ZYG-12 was mislocalized in ooc-5 gonads.

23 ly reduced Tspo levels in adrenal cortex and gonads.

24 eins silence transposon expression in animal gonads.

25 tropins that drive steroid production in the gonads.

26 work in the brain with little effects in the gonads.

27 ynthesized in the brain, adrenal glands, and gonads.

28 pts in cultured murine embryonic kidneys and gonads.

29 ely expressed in the germ cells of mammalian gonads.

30 s in the blood, morphology, and histology of gonads.

31 duces feminisation of male embryonic chicken gonads.

32 ises the female pathway in embryonic chicken gonads.

33 tes the Adamts16 gene in XX and XY embryonic gonads.

34 , heart, lungs, diaphragm, gut, kidneys, and gonads.

35 ome demethylated upon entry of PGCs into the gonads.

36 ns in thicklip gray mullet (Chelon labrosus) gonads.

37 ion in the post-temperature sensitive period gonads.

38 se in PGCs and a loss of germ cells from the gonads.

39 suppress transposable elements in the animal gonads.

40 ncoding VEGF receptor 2, in murine embryonic gonads.

41 steroidogenic cells in both male and female gonads.

42 ter than females instead of developing their gonads.

43 most of the somatic cells in both XX and XY gonads.

44 pecific Sox9 expression in developing murine gonads.

45 e testis-promoting gene Sox9 in embryonic XX gonads.

46 about Vtg levels, at least in marine mussel gonads.

47 F-acids) (38.2%) was detected in TAG of male gonads.

48 iencephalon, midbrain tegmentum, retina, and gonads.

49 pteropods but also the functioning of their gonads.

50 sex determination (SD) period and in mature gonads.

51 eased Adamts16 mRNA in cultured embryonic XY gonads (11.5 and 12.5 days postconception), and reduced

52 ion), and reduced Adamts16 transcripts in XX gonads (12.5 and 13.5 days postconception).

53 Of >7,000 transcripts found in the gonads, 243 (testes) and 3,600 (ovaries) occurred pairin

54 rred in the brain ( approximately 50%), male gonads (42%), and kidney (39%).

55 FA group in TAG of muscle (51.8%) and female gonads (47.8%) whereas high proportion of furan fatty ac

56 or component of both male (67.6%) and female gonad (58.6%) lipids.

57 d adult malignant GCTs, compared with normal gonads (a mixture of germ cells and somatic cells).

58 ent and function of several glands including gonads, adrenals, and thyroid.

59 d this protocol in adult testis, larval male gonads, adult intestine and Malpighian tubules.

60 with female-biased expression in developing gonads after the critical period during which sex is det

61 lly indifferent until the differentiation of gonads, after which sex differences in phenotype are cau

62 3 years and 9 months induced feminized male gonads, although the intersex condition was relatively m

63 crossing basement membranes and leaving the gonad altogether.

64 ulate testicular fate in the differentiating gonad and are the main regulators of spermatogenesis in

65 examined changes in steroid levels in brain, gonad and body muscle at either 24 hours or 6 days after

66 s DA levels and drives adult programs in the gonad and epidermis, thus conferring the irreversibility

67 istinct cell fate decisions in the mammalian gonad and even guards against transdifferentiation of ma

68 s and signalling in mesonephros and adjacent gonad and reveal that Stra8 expression in the fetal ovar

69 re initially co-expressed in the bipotential gonad and subsequently become male- or female-specific.

70 muscle, fat, liver, brain, gill, kidney and gonad and the tissue FA measured by gas-liquid chromatog

71 als from the somatic cells of the developing gonads and a suite of intrinsic receptors, signal transd

72 Morphological changes of gonads and accessory glands attributed to androgen effec

73 ation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues li

74 le (EpCAM), is also expressed in human fetal gonads and can be used as an effective selection marker

75 ntification of vitellogenin in marine mussel gonads and compared the results with those obtained with

76 d on the presence of individuals with mature gonads and conducted statistical analysis of the expecte

77 ssue of eels but maternally transferred into gonads and eggs.

78 oteins involved in the normal development of gonads and external genitalia.

79 the normal and pathologic development of the gonads and genitourinary tract and addresses the role of

80 (tissue in the body cavity comprising mainly gonads and hepatopancreas) differed significantly from m

81 nd/or immunohistochemistry also in embryonic gonads and in spermatids and granulosa cells of adult te

82 stages it became abundant in the developing gonads and osteogenic mesenchyme.

83 They act on gonads and promote their development and functions inclu

84 one in humans, produced by the adrenals, the gonads and the brain.

85 thway represses transposable elements in the gonads and thereby plays a vital role in protecting the

86 x differences precede differentiation of the gonads and/or are determined by non-gonadal effects of t

87 onic development stage at E34 in the XY(DSD) gonad, and high activation of the female specific genes,

88 tosis regulates germ cell homeostasis in the gonad, and propose a role for intercellular pressure in

89 in the brain, followed by liver, muscle, and gonads, and can be attributed to direct exposure to WWTP

90 terference with differentiation of brain and gonads, and consequently reproduction.

91 Females had more T than males in the gonads, and more E(2) in all tissues but there was no se

92 multiple GU tissues, including the kidneys, gonads, and reproductive ductal systems: the intermediat

93 ple vasa genes in the development of tilapia gonads, and will contribute to investigations of the mol

94 cell interactions necessary to create proper gonad architecture.

95 ertility, but their functions outside of the gonad are not well understood.

96 How sexually dimorphic gonads are generated is a fundamental question at the in

97 Sea urchin gonads are usually sold as a fresh chilled product.

98 Their essential roles include leading gonad arm outgrowth, serving as the germline niche, conn

99 the final U-shapes of the two hermaphrodite gonad arms are determined by migration of the distal tip

100 ished stem cell model system, the C. elegans gonad, as well as on two other model systems widely used

101 xpressed in somatic cells of male and female gonads, as well as in accessory reproductive tissues.

102 of transcripts of gonadotropin receptors in gonads, as well as less abundance of transcripts of estr

103 of human fetal testes explants called FEtal Gonad Assay (FEGA) with tissue obtained at 10 and 12 ges

104 en mature sperm and oocyte in the C. elegans gonad at the start of fertilization causes the oocyte to

105 As Amhr2-Cre is expressed in gonads at 12.5 dpc, these findings suggest preimplantati

106 reased Kdr transcripts in cultured embryonic gonads at multiple developmental stages.

107 re two major somatic cell types in mammalian gonads, but the mechanisms that control their differenti

108 Thus GONAD can bypass many complex steps in transgenic techno

109 embryogenesis; or (2) alterations of somatic gonad cell morphogenesis and differentiation in larval l

110 that DAF-16/FOXO activity in certain somatic gonad cells is required for germline progenitor maintena

111 Cell lineages of the early human gonad commit to one of the two mutually antagonistic org

112 P cluster fusion, germ cell ensheathment and gonad compaction.

113 ces of software we benchmarked on C. elegans gonad datasets.

114 cyst-derived embryonic stem cells (ESCs) and gonad-derived embryonic germ cells (EGCs) represent two

115 -Enk), and the opioid antagonist naloxone on gonad development in the Eastern lubber grasshopper, Rom

116 ms that control their differentiation during gonad development remain elusive.

117 phosphorylated proteins regardless of sex or gonad development stage.

118 ferentiation trajectory established early in gonad development under male- or female-producing temper

119 during four distinct stages of development: gonad development, gonad differentiation, development of

120 among female mussels at different stages of gonad development.

121 bility is incompatible with a normal pace of gonad development.

122 anism of somatic cell differentiation during gonad development.

123 f pelagic zooplankton for somatic growth and gonad development.

124 d energy in fat reserves, somatic growth and gonad development.

125 . elegans VAP homolog VPR-1 is essential for gonad development.

126 ation towards the region in which the future gonad develops.

127 is, testicular determination, gametogenesis, gonad differentiation, and possibly sex determination.

128 ct stages of development: gonad development, gonad differentiation, development of secondary sex char

129 ld, therefore, also play a role in zebrafish gonad differentiation.

130 the potential role of NF-kappaB in zebrafish gonad differentiation.

131 mportance of the nervous system for flatworm gonad differentiation.

132 not symmetric: loss of Fgf9 in XX Wnt4(-/-) gonads does not rescue their partial female-to-male sex-

133 also required for elastic deformation of the gonad during ovulation.

134 and respiration were up-regulated, while the gonad exhibited enrichment for DNA replication and trans

135 Indeed, piwi mutant larval gonads exhibited defective morphology and loss of Bam.

136 If this is the case, gonads explanted separately to culture should not coordi

137 The bipotential gonad expresses genes associated with both the male and

138 ryl esters (CEs) to the liver, adrenals, and gonads for product formation (bile acids and steroids).

139 In C. elegans, sexual dimorphism in gonad form and function largely originates in different

140 mechanism for the evolutionary plasticity of gonad form seen in nematodes [11-15].

141 Mid and Lola work in parallel in gonad formation and surprisingly Mid overexpression in a

142 ow temperatures during the initial stages of gonad formation develop as males, while those kept at hi

143 We find that gonad formation is regulated by multiple, independent pa

144 s in sexual development, but its function in gonad formation is still unclear.

145 In a screen for mutants affecting gonad formation we identified a SGP cell autonomous role

146 al region, and the male-bias increases after gonad formation.

147 c fashion in somatic cells of the developing gonads from 10.5 days postcoitum (dpc) to 12.5 dpc.

148 In gonads from male fish exposed to untreated OSPW the abun

149 onal composition and antioxidant activity of gonads from the sea urchin, Stomopneustes variolaris, in

150 To form a gonad, germ cells (GCs) and somatic gonadal precursor ce

151 uscle, with relatively low expression in the gonads, gizzard and subcutaneous fat tissues of chickens

152 In addition, whereas gonad growth was associated with an increase in DNA meth

153 Finally, a higher gonad growth was observed in fish from the reference sit

154 show that expression of ACS-1 in the somatic gonad guides the incorporation of C17ISO into certain ph

155 Some fish gonads had pathologic changes (e.g., infection, inflamma

156 appearance of female characteristics in male gonads, has been identified in a wide range of aquatic s

157 itions cannot be accurately evaluated unless gonads have fully matured under the new conditions.

158 an tissues and organs, including the kidney, gonads, heart and nervous system.

159 ions and adverse effects on reproduction and gonad histology at higher levels.

160 ession, plasma estradiol concentrations, and gonad histopathology were used to study biological condi

161 rphin were able to successfully colonize the gonad in 18% of recipient larvae and produce functional

162 onji genes are transcribed mostly within the gonad in adult oysters whereas they display a ubiquitous

163 Coalescence of the embryonic gonad in Drosophila melanogaster requires directed migra

164 s also confirm that signals from the somatic gonad in turn ensure that the sex appropriate gamete is

165 covered pairing-induced processes within the gonads including stem cell-associated and neural functio

166 Ectopic DMRT1 expression in female gonads induces localised SOX9 and AMH expression.

167 GnRH-1-ir cell bodies do not differ between gonad-intact breeders and subordinates within or between

168 to olfactory bub glomeruli in unmanipulated (gonad-intact) adult mice from both sexes, and found that

169 -response regulation between neurons and the gonad involving serotonin.

170 The formation of the Drosophila embryonic gonad, involving the fusion of clusters of somatic gonad

171 from their place of origin to the embryonic gonad is an essential reproductive feature in many anima

172 As SOX9 biological role in mammalian gonads is to determine Sertoli cells, we correlated this

173 However, the role of PRAME in normal gonads is unknown.

174 tion mutation, Cys342Tyr substitution in the gonad leads to loss of function, as demonstrated by sex

175 correlated with the prevalence of histologic gonad lesions.

176 T_F_OV) and XY(DMY-) female medaka (TA_F_OV) gonad libraries.

177 ndances of transcripts of genes in the brain-gonad-liver (BGL) axis in male and female fathead minnow

178 The highest TTX levels in gonads, livers, intestines and skins of female fish were

179 Changes in the levels of TTX in the gonads, livers, intestines, skins and muscles as a funct

180 in slow developing marine species with long gonad maturation times, as the effects of altered condit

181 n our experiments (e.g., during diapause and gonad maturation), and for contaminant transfer to eggs

182 A methylation status of their oocytes during gonad maturation.

183 from hemogenic endothelium within the aorta, gonad, mesonephros (AGM) region of the mammalian embryo

184 de of the PGE2-cAMP-PKA pathway in the aorta-gonad-mesonephros (AGM) abolished enhancement in hematop

185 poietic stem cells (HSCs) arise in the aorta-gonad-mesonephros (AGM) and mature as they transit throu

186 poietic stem cell emergence, viz., the aorta-gonad-mesonephros (AGM) and the fetal liver at 10.5-11.5

187 y putative direct Notch targets in the aorta-gonad-mesonephros (AGM) embryonic tissue by chromatin pr

188 hematopoietic stem cells (HSCs) in the aorta-gonad-mesonephros (AGM) of the developing mouse embryo.

189 aft irradiated adult mice arise in the aorta-gonad-mesonephros (AGM) on embryonic day 11.5 (E11.5).

190 Of them, the aorta-gonad-mesonephros (AGM) region drew particular attention

191 helium fates concurrently occur in the aorta-gonad-mesonephros (AGM) region prior to haematopoietic s

192 ascent HSCs were not released from the aorta-gonad-mesonephros (AGM) region, as evidenced by the accu

193 etic stem cells (HSCs) emerge from the aorta-gonad-mesonephros (AGM) region, but the molecular regula

194 essels such as the dorsal aorta of the aorta-gonad-mesonephros (AGM) region, suggesting that signals

195 ke cell population that resides in the aorta-gonad-mesonephros (AGM) region.

196 the ventral domain of the aorta in the aorta-gonad-mesonephros (AGM) region.

197 ls harvested from embryonic day 9 (E9) aorta-gonad-mesonephros (AGM) regions of GATA2 null embryos sh

198 Rare endothelial cells in the aorta-gonad-mesonephros (AGM) transition into hematopoietic st

199 merge, similar to hematopoiesis in the aorta-gonad-mesonephros (AGM).

200 hematopoietic stem cells (HSC) in the aorta-gonad-mesonephros by abrogating Smad1 expression and the

201 orming assay and in embryonic day 10.5 aorta-gonad-mesonephros explants.

202 pool undergoes dramatic growth in the aorta-gonad-mesonephros region and by E11.5 reaches the size t

203 progenitors are first generated in the aorta-gonad-mesonephros region between days 27 and 40 of human

204 cushion and atria earlier than in the aorta-gonad-mesonephros region, and is transient and definitiv

205 e: 1) CX3CR1(+) cells localized to the aorta-gonad-mesonephros region, and visualized at embryonic da

206 SCs as they are first generated in the aorta-gonad-mesonephros region, but at later developmental sta

207 to blood vessel walls in the yolk sac, aorta-gonad-mesonephros region, embryonic liver, and fetal bon

208 hematopoietic cluster formation in the aorta-gonad-mesonephros region; embryonic-to-adult transplanta

209 para-aortic splanchnopleura, yolk sac, aorta-gonad-mesonephros, liver, and bone marrow (BM).

210 oietic stem cells (HSCs) emerge in the aorta-gonads-mesonephros (AGM) region of the embryo.

211 n by de novo expression of Hes5 in the aorta/gonad/mesonephros (AGM) region of Hes1 mutants.

212 d hematopoietic stem cells (HSCs) from aorta/gonad/mesonephros (AGM) regions of midgestation mouse em

213 aw negatively regulates JNK signaling during gonad morphogenesis, and increased JNK signaling is suff

214 During gonad morphogenesis, SGPs send out cellular extensions t

215 In Caenorhabditis elegans gonad morphogenesis, the final U-shapes of the two herma

216 that in mice germline stem cells compete for gonad niches, and in mice and humans, blood-forming stem

217 and Sm-Sox19 are expressed differentially in gonads, no sex differences in their expression were obse

218 nally active oocyte precursors in the distal gonad, not in transcriptionally inactive oocytes that sy

219 In the male gonad of Drosophila melanogaster, germline cells are com

220 FGSCs were able to successfully colonize the gonad of sterile recipient fish and generate functional

221 The myoepithelial sheath in the somatic gonad of the nematode Caenorhabditis elegans has nonstri

222 In the gonad of the nematode worm Caenorhabditis elegans, ring

223 cyp19a1a were significantly increased in the gonad of the ZZ dmrt1 mutant.

224 cribed preferentially or specifically in the gonads of both genders, we uncovered pairing-induced pro

225 3 were also very active transcriptionally in gonads of female and intersex mullets, in comparison to

226 The gonads of female fish were toxic in all seasons (>2mug/g

227 PCR quantification of 5S rRNA expression, in gonads of histologically sexed individuals from differen

228 toxic in all seasons (>2mug/g), whereas the gonads of male fish were only toxic in the spring and au

229 In gonads of teneral and 15-day old insects, Spiroplasma de

230 pete less successful competitors both in the gonads of the genotype partner from which they arise and

231 ype partner from which they arise and in the gonads of the natural parabiotic partners.

232 The gonads of the remaining fish stayed undifferentiated unt

233 erm cells (PGCs) is determined in developing gonads on the basis of cues from somatic cells.

234 ndergoes a stereotyped migration that guides gonad organogenesis, occurs with precise timing, and req

235 sterol in mitochondria of adrenal glands and gonads/ovaries.

236 Here we show that gonad pairs from embryos incubated at the PvT share a st

237 DE-cadherin strongly enhances the raw mutant gonad phenotype, while increasing DE-cadherin function r

238 al mechanisms: (1) reduced number of somatic gonad precursors (SGP cells) specified during embryogene

239 nadal primordium, which contains two somatic gonad precursors (SGPs) and two primordial germ cells (P

240 les to three regulatory cells of the somatic gonad primordium in young larvae.

241 mig-38 is expressed in the gonad primordium, and expression continues throughout DT

242 tion products was detected during storage of gonads recovered from urchins held in air, with final K-

243 ld in air: 82.87 and 52.95), was observed in gonads recovered from urchins held in air.

244 During baseline conditions in mice whose gonads remained intact, males had more total sleep and n

245 ular dynamics and physical forces within the gonad remains poorly understood.

246 Deletion of either Fgf9 or Fgfr2 in an XY gonad resulted in up-regulation of Wnt4 and male-to-fema

247 Transcript profiling of the gonads revealed 10 mg/L Roundup and glyphosate induced c

248 matography-mass spectrometry (GC/MS) in male gonad samples, including less common 12,15-epoxy-13,14-d

249 In XY gonads, sex-determining region Y (SRY) triggers fibrobla

250 migratory distal tip cells and the proximal gonad sheath, where it becomes enriched in response to t

251 of live urchin's post-harvest conditions on gonad shelf-life, gonads were extracted either immediate

252 st-harvest handling can negatively impact on gonad shelf-life.

253 Masculinised gonads show evidence of cord-like structures and retarde

254 Mutant gonads showed a loss of cell polarity in the surface epi

255 y and quantitative real-time-PCR analysis of gonads showed elevated expression of NF-kappaB-regulated

256 al, characterized by obvious feminization of gonads, significant down-regulation of testicular marker

257 In mammalian embryonic gonads, SOX9 is required for the determination of Sertol

258 more elaborate pathway centered on the three gonad-specific Argonaute proteins (Piwi, Aubergine, and

259 Here, we identified Vreteno (Vret), a novel gonad-specific protein essential for germline developmen

260 Piwi-interacting RNAs (piRNAs) are gonad-specific small RNAs that provide defense against t

261 expression in microarray data from mammalian gonads, specifically during meiotic initiation and proph

262 e of sex, reproductive state, or presence of gonads, substantial numbers of kisspeptin-ir cell bodies

263 Estimated Se concentrations in yellow perch gonads suggest that in two of our study lakes one-third

264 vealed a lasting thermal effect on zebrafish gonads, suggesting new avenues for detection of function

265 In XY gonads, testis development is initiated by upregulation

266 Here, we report a key role for the male gonad, testosterone, and androgen receptor (AR) in CNS r

267 ns showed higher concentrations in liver and gonad than in muscle tissues.

268 For both sexes, E(2) was higher in the gonad than in other tissues while androgens were higher

269 tile fish that possessed minimally-developed gonads that lacked any gametes.

270 ression of Dmrt1 was induced in ZW embryonic gonads that were masculinized by aromatase inhibitor tre

271 and function of the anchor cell (AC) of the gonad, the critical organizer of uterine and vulval deve

272 Although its primary location is the gonad, the FSHR has also been reported in extragonadal t

273 present in select somatic cells outside the gonads, the role of a non-gonadal somatic piRNA pathway

274 ations and is specified within the embryonic gonad, thus making it an excellent model for studying ni

275 (FA) composition was analyzed in muscle and gonad tissues of marketed common carp (Cyprinus carpio).

276 ading the ovary, and sometimes breaching the gonad to infiltrate other tissues.

277 germ cell-derived signal acts on the somatic gonad to promote female development directly or indirect

278 rdinated rhythmic pumping and in the somatic gonad to promote ovulation.

279 rived signal acts on the bipotential somatic gonad to promote the female-specific program.

280 nes must remain active in the differentiated gonads to avoid genetic sex reprogramming, as described

281 sion of Sry in pre-Sertoli cells directs the gonad toward a male-specific fate.

282 linary team and include gonadectomy to avoid gonad tumours in later life, appropriate sex-hormone rep

283 The cells in the early bipotential gonad undergo de novo organization to form testis cords

284 Preconception radiation doses to the gonads, uterus, and pituitary gland and administered che

285 Total phenol content of the gonad was 9.90+/-0.01 mg GAE/g and the IC50 of the extra

286 Using GONAD, we show that NAs (e.g., eGFP mRNA or Cas9 mRNA/sg

287 A small reduction in gonad weight was detected at the vents, but no differenc

288 ing revealed that fish with undifferentiated gonads were all males, who grew larger than the genetic

289 post-harvest conditions on gonad shelf-life, gonads were extracted either immediately after harvestin

290 c chemotherapy and radiotherapy doses to the gonads were not associated with genetic defects in child

291 The gonads were rich in essential amino acids (ca. 32.1% of

292 Gonads were subsequently washed in brine and stored at 4

293 aggression and dominance, and ar and cyp17 (gonad) were elevated in nonexposed males paired with EE(

294 d in both germ-line and somatic cells in the gonad, where it is responsible for piRNA biogenesis and

295 isoform specific requirement for lola in the gonad which is distinct from that in nervous system deve

296 ring-dependent differentiation of the female gonads which finally leads to egg synthesis.

297 and somatic cell differentiation in the male gonad, which can be rescued by reducing Arm protein leve

298 ian sex determination initiates in the fetal gonad with specification of bipotential precursor cells

299 that vitellogenin is only detected in female gonads with expression levels that are rather variable a

300 of sex and effects of xenosterogens in fish gonads, with potential technological applications in the