ライフサイエンスコーパス: gonadal hormone

1 afferents is highly responsive to changes in gonadal hormones.

2 in the arcuate nucleus, a target tissue for gonadal hormones.

3 al to hippocampal function and influenced by gonadal hormones.

4 pe are caused by the differential effects of gonadal hormones.

5 h organizational and activational effects of gonadal hormones.

6 and thus expression may be regulated also by gonadal hormones.

7 ex chromosome genes that are not mediated by gonadal hormones.

8 ion and behavior are regularly attributed to gonadal hormones.

9 these differences precede the influences of gonadal hormones.

10 ate regulation of the CNS by male and female gonadal hormones.

11 in the male genome, without any mediation by gonadal hormones.

12 ding attributed to the protective effects of gonadal hormones.

13 red from mice that were capable of secreting gonadal hormones.

14 e brain has been attributed to the action of gonadal hormones.

15 d secretion of gonadotropins and, therefore, gonadal hormones.

16 dence from animal studies indicates that the gonadal hormone 17beta-estradiol (E(2)) impacts the stru

17 ary outcome measure) and had blood drawn for gonadal hormone and neurosteroid levels determined on ea

18 These data demonstrate a link between gonadal hormones and APC activity and suggest that these

19 ie a two-way interaction between circulating gonadal hormones and behavioral responses to socially sa

20 dimorphism have emphasized the importance of gonadal hormones and cell-autonomous influences in mamma

21 Correlations between circulating gonadal hormones and certain prefrontal functions have a

22 e hypothalamopituitary axis and suggest that gonadal hormones and female presence independently regul

23 central nervous system (CNS) factors, genes, gonadal hormones and receptors, genitalia, and social/en

24 Here, we review the mechanisms by which gonadal hormones and sex chromosome complement each cont

25 ales that depends on the interaction between gonadal hormones and the central mu-opioid system.

26 e organizational and activational effects of gonadal hormones and to genes on the sex chromosomes.

27 alamus, brain receptors for gonadotropic and gonadal hormones are concentrated in specific subcortica

28 Gonadal hormones are known to act during development to

29 Many effects of these gonadal hormones are mediated by nuclear steroid hormone

30 It seems that gonadal hormones are responsible for adaptive variation;

31 se dimorphisms are maintained by circulating gonadal hormones, as castration of adult male rats reduc

32 nxiety were not because of altered levels of gonadal hormones, as serum estrogen and progesterone lev

33 Removing gonadal hormones before puberty eliminates these sex dif

34 Removing gonadal hormones before puberty eliminates these sex dif

35 Gonadal hormones contribute to ischemic neuroprotection,

36 y and provide a potential mechanism by which gonadal hormones could regulate the maturation of the as

37 Among evolocumab-treated patients, gonadal hormones did not change from baseline to week 52

38 Here, we report that manipulations of gonadal hormones do significantly alter the maturation o

39 ned for a female phenotype unless exposed to gonadal hormones during a perinatal sensitive period.

40 brain can be attributed to known effects of gonadal hormones during development or adulthood, and fa

41 l nervous system to low levels of endogenous gonadal hormones during development, the central nervous

42 Exposure to gonadal hormones during perinatal life influences later

43 in photic responsiveness are independent of gonadal hormone effects during development.

44 halves of the brain were exposed to a common gonadal hormone environment, the lateral differences ind

45 An emerging hypothesis is that fluctuating gonadal hormones, especially estrogen, in the menstrual

46 inatal sensitive period, when organizational gonadal hormones establish the sexually dimorphic brain,

47 llowing experiments examined the role of the gonadal hormone estrogen in comparison to the neurotroph

48 adverse effects were observed in steroid or gonadal hormones, even at very low LDL-C levels.

49 Importantly, duration of gonadal hormone exposure, weight, and height at maturity

50 nation of underlying genetic differences and gonadal hormone exposure.

51 (HUVECs) were propagated in phenol red-free gonadal hormone-free medium and pretreated with 17 beta-

52 trogen receptor-positive) were propagated in gonadal hormone-free medium and were E2-pretreated for 4

53 stimulating hormones from the pituitary, and gonadal hormones from the ovaries and testes.

54 ted status, suggesting that dysregulation of gonadal hormone function may be a characteristic trait o

55 pothalamus become sexually differentiated by gonadal hormones giving rise to sexually differentiated

56 is more common in males than females; thus, gonadal hormones have been a focal point for research in

57 Although gonadal hormones have been shown to influence the expres

58 specting the breadth and depth of the impact gonadal hormones have on brain functioning and its rich

59 involving neonatal organizational effects of gonadal hormones have previously been shown to profoundl

60 Gonadal hormones have primarily slow, genomically mediat

61 f the disease in jck male mice, while female gonadal hormones have protective effects.

62 astrocytes persisted even in the absence of gonadal hormones in adulthood, suggesting that androgens

63 in these sites is influenced by circulating gonadal hormones in adults, which may be related to chan

64 discriminable, suggesting opposite roles for gonadal hormones in influencing male and female olfactor

65 ssion is sexually dimorphic and modulated by gonadal hormones in lateral regions of the rat dorsal st

66 J and SJL/J mice to assess the role of adult gonadal hormones in regulating clinical and histopatholo

67 nessed increased confusion as to the role of gonadal hormones in the development of neuroeffectors fo

68 tivity are sexually dimorphic or affected by gonadal hormones in the MePD.

69 ffects of stress, where the rapid decline of gonadal hormones in women combined with cellular aging p

70 In adulthood, gonadal hormones, including both androgens and estrogens

71 PR expression, suggesting the presence of a gonadal hormone-independent PR regulatory mechanism.

72 Thus, dephosphorylation of tau is gonadal hormone-independent, but while its hyperphosphor

73 activity of c-Jun NH(2)-terminal kinase was gonadal hormone-independent.

74 tradiction between the dependence on ERK for gonadal hormone-induced neuroprotection and the lack of

75 ontext of genetic heterogeneity, circulating gonadal hormones influence both clinical and histopathol

76 Gonadal hormones influence brain functions, including mo

77 We report that gonadal hormones influence brain mitochondrial ROS produ

78 onitase activity, suggesting that endogenous gonadal hormones influence mitochondrial ROS production

79 nt work illustrating how sex differences and gonadal hormones influence sleep and circadian rhythms t

80 uggest a limited organizational-activational gonadal hormone interaction in the mediation of systemic

81 e (ERbeta effect), while having no effect on gonadal hormone levels (ERalpha effect) at 10x the effic

82 Fluctuations in gonadal hormone levels trigger the symptoms, and thus in

83 of these sex differences, but whether adult gonadal hormones maintain the increased number and compl

84 nisms responsible for the effects of the two gonadal hormones may be different.

85 Gonadal hormones may exert permanent organizational effe

86 ded that prenatal, organizational effects of gonadal hormones may play a role in the development of A

87 ng vehicle treatment, the presence of female gonadal hormones may underlie the sex differences in mor

88 smission to the GnRH neurons, independent of gonadal hormone milieu.

89 involving the adult activational effects of gonadal hormones minimally alter these analgesic sex dif

90 Gonadal hormones modulate behavioral responses to sexual

91 We then assessed in vivo effects of gonadal hormones on brain mitochondrial oxidative stress

92 ural mechanisms underlying the influences of gonadal hormones on human behavior are beginning to be i

93 The influence of gonadal hormones on multiple sclerosis (MS) is not well

94 itary males independent of pheromonal input, gonadal hormones, opponents, or social context.

95 here is also a sex difference independent of gonadal hormones: OVX females exhibit a greater magnitud

96 t experimental data in rodents, suggest that gonadal hormones play a role in modulating this system.

97 nd gonadectomized male rats, suggesting that gonadal hormones play an important role in modulating th

98 This review discusses the role that gonadal hormones play in these sexually dimorphic patter

99 In evolutionary terms, gonadal hormones precede adrenal hormones.

100 printed genes is most likely attributable by gonadal hormones rather than by sex chromosome complemen

101 To investigate the role of gonadal hormones, rats were ovariectomized (OVX), orchie

102 Gonadal hormones regulate dopamine release in the MPOA o

103 al steroid hormones and is a likely site for gonadal hormone regulation of sexually dimorphic social

104 Are sex differences in levels of circulating gonadal hormones robust enough to account for the full s

105 changes during puberty that may be driven by gonadal hormone secretion during this developmental peri

106 x chromosomes and the consequent sex-typical gonadal hormone secretions may play important roles in t

107 o derive exclusively from sex differences in gonadal hormone secretions.

108 rient intakes may be associated with altered gonadal hormone status of these dieters.

109 robust immediate early gene expression after gonadal hormone stimulation.

110 ence indicates that prenatal exposure to the gonadal hormone, testosterone, influences the developmen

111 rentiation of the gonads, which then secrete gonadal hormones that act directly on tissues to induce

112 onding and in other hypothalamic sites after gonadal hormone treatments sufficient to activate lordos

113 s in model systems have revealed that, while gonadal hormones undoubtedly play an important role in s

114 adotropins without the concomitant loss of a gonadal hormone, we crossed INH(-/-) mice with a transge

115 s were not the consequence of the actions of gonadal hormones, we induced gonadal sex reversal to alt

116 , cortisol, adrenocorticotropic hormone, and gonadal hormones were analyzed at baseline and week 52.