ライフサイエンスコーパス: gordonii

1 w-pH-dependent expression of ADS genes in S. gordonii.

2 edent oral biofilm constituent Streptococcus gordonii.

3 A from mixed cultures of S. sanguinis and S. gordonii.

4 hogenic potential of F. nucleatum than of S. gordonii.

5 . gingivalis in heterotypic biofilms with S. gordonii.

6 forms biofilms on substrata of Streptococcus gordonii.

7 imal coadhesion between P. gingivalis and S. gordonii.

8 ely related Streptococcal species such as S. gordonii.

9 oxidative stress response (osr) operon in S. gordonii.

10 uctose phosphotransferase system (PTS) in S. gordonii.

11 n of GAPDH may be a similar adaptation by S. gordonii.

12 tivity of another species, H2O2-producing S. gordonii.

13 sed in the cdhR mutant after contact with S. gordonii.

14 elevated accumulation on a substratum of S. gordonii.

15 ies Streptococcus sanguinis or Streptococcus gordonii.

16 sfer of plasmid DNA from E. faecalis into S. gordonii.

17 eptor polysaccharides (RPS) of Streptococcus gordonii 38 and Streptococcus oralis J22 was eliminated

18 Type 2Gn RPS of Streptococcus gordonii 38 and type 2G RPS of Streptococcus oralis J22

19 ransferases encoded by downstream wefC in S. gordonii 38 and wefH in S. oralis 34.

20 -Gal and UDP-GalNAc for RPS production by S. gordonii 38 depends on the dual specificity of the epime

21 he cell wall polysaccharide of Streptococcus gordonii 38 functions as a coaggregation receptor for su

22 o identify and partially characterize the S. gordonii 38 RPS gene cluster.

23 and wefD in the type 2Gn gene cluster of S. gordonii 38 with wefF and wefG from the type 2G cluster

24 olysaccharide in transformable Streptococcus gordonii 38.

25 produced by the wefB-deficient mutant of S. gordonii 38.

26 ently inhibits P. gingivalis adherence to S. gordonii (50% inhibitory concentration = 1.3 microM) and

27 pecies plaque interactions, the effect of S. gordonii AbpB on S. mutans Gtf-B activity was also teste

28 tudy assessed a multi-species (Streptococcus gordonii, Actinobacillus actinomycetemcomitans, and Fuso

29 The S. gordonii adc operon, consisting of the four ORFs adcR, a

30 onii and that the transposon insertion in S. gordonii adcR::Tn917-lac had resulted in a polar mutatio

31 occus oralis (RPS bearing) and Streptococcus gordonii (adhesin bearing).

32 Next, putative S. gordonii adhesins were analyzed for contributions to int

33 at results in increased expression of the S. gordonii alpha-amylase-encoding gene amyB.

34 determinant of colonization by Streptococcus gordonii, an oral commensal and opportunistic pathogen o

35 s role in biofilm formation by Streptococcus gordonii, an organism that colonizes human tooth enamel

36 performed comparative analyses on 14 new S. gordonii and 5 S. sanguinis strains using various bioinf

37 Contact between S. gordonii and a CdhR mutant resulted in increased transcr

38 two other initial colonizers, Streptococcus gordonii and Actinomyces oris, as well as with Veillonel

39 onal changes that accompany competence in S. gordonii and form a basis for future intra- and interspe

40 ermed P57AS3 (P57), was isolated from Hoodia gordonii and found to have homologies to the steroidal c

41 xamined their subcellular localization in S. gordonii and in Escherichia coli expressing the streptoc

42 required for disulfide bond formation in S. gordonii and indicate that this enzyme may represent a n

43 GspB is glycosylated in the cytoplasm of S. gordonii and is then transported to the cell surface via

44 n is involved in manganese acquisition in S. gordonii and manganese homeostasis and appears to modula

45 o bacterial species, commensal Streptococcus gordonii and pathogenic Streptococcus mutans.

46 rstanding of the regulation of the ADS in S. gordonii and related organisms is needed to develop ways

47 pment of anti-adhesive agents that target S. gordonii and related streptococci.

48 mab, protected 45%-88% of animals against S. gordonii and S. aureus IE (P < .05).

49 ited the interaction of gp340 with intact S. gordonii and S. mutans cells, respectively.

50 While both S. gordonii and S. mutans were abundant colonizers of rat's

51 r, P. gingivalis grew in combination with S. gordonii and S. oralis, demonstrating its ability to ove

52 We revealed S. gordonii and S. sanguinis harbor open pan-genomes and sh

53 hts into the genetic distinctions between S. gordonii and S. sanguinis, which yields understanding of

54 rize the related pheromone determinant in S. gordonii and show that the peptide it encodes, gordonii-

55 r activity is also secreted by Streptococcus gordonii and Staphylococcus aureus.

56 Streptococcus gordonii and Streptococcus mutans avidly colonize teeth.

57 Streptococcus gordonii and Streptococcus sanguinis are pioneer coloniz

58 l flora (Streptococcus mutans, Streptococcus gordonii and Streptococcus sanguinis) to determine the u

59 revealed that S. oralis, like Streptococcus gordonii and Streptococcus sanguinis, binds platelets vi

60 ively, in the S-ECC group, and Streptococcus gordonii and Streptococcus sanguinis, which were 5- and

61 ginine metabolism is tightly regulated in S. gordonii and that arginine is critical for gene regulati

62 adcRCBA are cotranscribed as an operon in S. gordonii and that the transposon insertion in S. gordoni

63 arginine-responsive regulatory network of S. gordonii and the basis for conditional arginine auxotrop

64 ulture with the oral commensal Streptococcus gordonii and the opportunistic commensal Fusobacterium n

65 ress tolerance between the oral commensal S. gordonii and the oral pathogen Streptococcus mutans.

66 mice were first infected with Streptococcus gordonii and then challenged with P. gingivalis in the a

67 In a closed system containing S. gordonii and V. atypica, flow cytometric analysis showed

68 Streptococcus gordonii and Veillonella atypica, two early colonizing m

69 Streptococcus gordonii and Veillonella atypica, two early-colonizing m

70 to Streptococcus pyogenes, S. agalactiae, S. gordonii, and Escherichia coli.

71 zed, and Streptococcus mutans, Streptococcus gordonii, and Streptococcus sanguinis were chosen to for

72 nd fruI are cotranscribed as an operon in S. gordonii, and the transposon insertion in S. gordonii fr

73 Oral streptococci such as Streptococcus gordonii are facultative anaerobes that initiate biofilm

74 asp5) essential for export in Streptococcus gordonii are missing in S. aureus.

75 Oral streptococci, such as Streptococcus gordonii, are the predominant early colonizers that init

76 on, indicating that arcB levels may limit S. gordonii arginine biosynthesis.

77 als provide encouragement that the use of S. gordonii as a live mucosal vaccine vector is a feasible

78 By using Streptococcus gordonii as a model organism for streptococcal H(2)O(2)

79 Using Streptococcus gordonii as a model, we now show the mechanistic basis o

80 In Streptococcus gordonii, Asp2 is required for the transport of the SRR

81 The same RPS has now been identified from S. gordonii AT, a partially sequenced strain.

82 nent system regulated in association with S. gordonii biofilm formation in vitro.

83 ast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-defi

84 nced heterotypic P. gingivalis-Streptococcus gordonii biofilm formation.

85 sponse, some of which may be important in S. gordonii biofilm formation.

86 h altered microcolony architecture within S. gordonii biofilms formed in saliva during a time frame c

87 uses release of DNA from S. sanguinis and S. gordonii but does not result in obvious lysis of cells.

88 microcolonies on substrata of Streptococcus gordonii but not on Streptococcus mutans.

89 onstrated that cell protein extracts from S. gordonii, but not from A. naeslundii, interfered with S.

90 S. oralis coaggregated with S. gordonii by an RPS-dependent mechanism, and both strepto

91 pA, and eep each resulted in the ablation of gordonii-cAM373 activity in culture supernatants.

92 , the last 7 residues of which represent the gordonii-cAM373 heptapeptide SVFILAA.

93 rdonii and show that the peptide it encodes, gordonii-cAM373, does indeed induce transfer of plasmid

94 Streptococcus gordonii can mediate its platelet attachment through a c

95 Surprisingly, S. sanguinis and S. gordonii cell integrity appears unaffected by conditions

96 The Streptococcus gordonii cell surface glycoprotein GspB mediates high-af

97 Conversely, aggregation of S. gordonii cells by fluid-phase gp340 was not affected by

98 Planktonic Streptococcus gordonii CH1 killed HUVEC over a 5-h period by peroxidog

99 Following invasion by S. gordonii CH1, HUVEC monolayers showed 63% cell lysis ove

100 ly similar to Hsa, a protein expressed by S. gordonii Challis that has been characterized as a sialic

101 though Hsa is required for the binding of S. gordonii Challis to sialic acid, most of the Hsa express

102 ntaining V. atypica expressed GFP; nearby S. gordonii colonies that lacked V. atypica did not express

103 Caries induction reflected S. mutans or S. gordonii colonization abundance: the former highly cario

104 interaction has been proposed to promote S. gordonii colonization at multiple sites within the host.

105 Streptococcus gordonii colonizes multiple sites within the human oral

106 nes) exposed on the surface of Streptococcus gordonii commensal bacterial vectors: (i) a shorter N-te

107 S. gordonii competed with S. sanguinis more effectively tha

108 Results supported published findings on S. gordonii competence, showing up-regulation of 12 of 16 g

109 ica, flow cytometric analysis showed that S. gordonii containing the PamyB-'gfp reporter plasmid exhi

110 in this observation, we hypothesized that S. gordonii could compete with S. sanguinis to adhere to sa

111 at were infected with either 10(9) CFU of S. gordonii DL-1 or 10(7) CFU of P. gingivalis 33277 did no

112 as used together with an antibody against S. gordonii DL1 (anti-DL1).

113 I polypeptides and Hsa in interactions of S. gordonii DL1 (Challis) with host receptors.

114 t Hsa directs primary adhesion events for S. gordonii DL1 (Challis) with immobilized gp340, epithelia

115 Adhesion of S. gordonii DL1 cells to gp340 was sialidase sensitive, ver

116 The accessory Sec system in Streptococcus gordonii DL1 is a specialized export system that transpo

117 regation, streptococci such as Streptococcus gordonii DL1 recognize receptor polysaccharides (RPS) bo

118 milarly to sHA, yet 10- to 50-fold excess S. gordonii DL1 reduced binding of S. sanguinis SK36 by 85

119 and AgI/II proteins mediated adhesion of S. gordonii DL1 to human HEp-2 epithelial cells.

120 n and initial biofilm formation on teeth, S. gordonii DL1 was incubated with saliva-coated hydroxyapa

121 Five strains, including S. gordonii DL1, caused severe disease, while the other two

122 In Streptococcus gordonii DL1, inactivation of the ccpA gene and a gene e

123 lonizers of the tooth surface (Streptococcus gordonii DL1, Streptococcus oralis 34, and Actinomyces n

124 r biofilm formation on sHA than wild-type S. gordonii DL1.

125 ch greater recovery of rifampin-resistant S. gordonii DLl than of streptomycin-resistant S. gordonii

126 S. gordonii does not appear to be a good candidate for repl

127 In contrast, S. gordonii early CSP-responsive genes were not preceded by

128 The arginine deiminase system (ADS) of S. gordonii enables cells to produce, ornithine, ammonia, C

129 We also identified determinants in S. gordonii encoding a signal peptidase and an Eep-like zin

130 eparation for clinical trials to evaluate S. gordonii engineered to express group A streptococcal M p

131 ry Sec system in E. coli matched those in S. gordonii, establishing the validity of this approach.

132 Thus, A. naeslundii stabilizes S. gordonii expression of arginine biosynthesis genes in co

133 olated from the same intraoral sites, yet S. gordonii fails to be excluded and survives as a species

134 o participate in metabolic communication; S. gordonii ferments carbohydrates to form lactic acid, whi

135 However, infection with 10(9) CFU of S. gordonii followed by 10(7) CFU of P. gingivalis induced

136 ation of approximately 12 +/- 5 muM above S. gordonii, followed by a gradual decrease in H2O2 concent

137 gordonii, and the transposon insertion in S. gordonii fruK::Tn917-lac resulted in a nonpolar mutation

138 ase found in culture fluids of Streptococcus gordonii FSS2, was purified and characterized, and its g

139 Cell fractionation studies with S. gordonii further corroborated these microscopy results.

140 results in increased transcription of the S. gordonii gene amyB, encoding an alpha-amylase.

141 The majority of S. gordonii genes examined were observed to be downregulate

142 Streptococcus gordonii genes involved in beta-glucoside metabolism are

143 used to quantify changes in expression of S. gordonii genes known or thought to be involved in biofil

144 A DNA microarray identified Streptococcus gordonii genes regulated in response to coaggregation wi

145 creening a plasmid integration library of S. gordonii, genes were identified that are crucial for the

146 S. gordonii glucosyltransferase (GtfG) and amylase-binding

147 The Streptococcus gordonii glucosyltransferase gene, gtfG, is positively r

148 The results suggest that S. gordonii governs the development of heterotypic oral bio

149 ultures containing coaggregates, however, S. gordonii grew to high cell density at low arginine conce

150 ion by Streptococcus mutans or Streptococcus gordonii grown in human plasma.

151 , low concentrations of arginine promoted S. gordonii growth, whereas high concentrations (> 5 mM arg

152 the predicted catalytic triad of Asp2 of S. gordonii had no effect upon GspB transport but did resul

153 In mixed cultures of S. mutans and S. gordonii harbouring a shuttle plasmid, plasmid DNA trans

154 However, strain FSS2 of S. gordonii has been found to produce several extracellular

155 atory network that controls P. gingivalis-S. gordonii heterotypic communities.

156 ry for platelet aggregation, and modulate S. gordonii-host engagements into biologically productive p

157 f cdhR is elevated following contact with S. gordonii; however, regulation of cdhR did not occur in a

158 S. mutans out-competed S. gordonii in in vivo plaque biofilm.

159 n normal adhesion and biofilm function of S. gordonii in response to exogenous oxidants therefore msr

160 th beta-glucoside metabolism may regulate S. gordonii in vitro adhesion, biofilm formation, growth, a

161 ignificantly impacted by F. nucleatum and S. gordonii included the mitogen-activated protein kinase (

162 S. gordonii-infected mice that were subsequently challenged

163 , Streptococcus sanguinis, and Streptococcus gordonii, inhibit the growth of P. aeruginosa and that t

164 ed production of these cytokines, whereas S. gordonii inhibited secretion from the epithelial cells.

165 oneer oral bacteria, including Streptococcus gordonii, initiate the formation of oral biofilms on too

166 lis and the accessory pathogen Streptococcus gordonii interact to form communities in vitro and exhib

167 multidimensional aspect to P. gingivalis-S. gordonii interactions and establish pABA as a critical c

168 The oral commensal bacterium Streptococcus gordonii interacts with salivary amylase via two amylase

169 ntal plaque colonizers such as Streptococcus gordonii interfere with the subsequent colonization of S

170 ggregation regulator (ScaR) of Streptococcus gordonii is a manganese-dependent transcriptional regula

171 Streptococcus gordonii is a pioneer colonizer of the teeth, contributi

172 Streptococcus gordonii is a primary colonizer of the multispecies biof

173 Streptococcus gordonii is a primary etiological agent in the developme

174 Streptococcus gordonii is an oral commensal and an early coloniser of

175 The accessory Sec system of Streptococcus gordonii is comprised of SecY2, SecA2, and five proteins

176 In vitro, S. gordonii is conditionally auxotrophic for arginine in mo

177 r findings illustrate that H2O2-producing S. gordonii is dominant while the buffering capacity of sal

178 The accessory Sec system of Streptococcus gordonii is essential for transport of the glycoprotein

179 n of fructose transport and metabolism in S. gordonii is intricately tied to carbon catabolite contro

180 Platelet binding by Streptococcus gordonii is mediated in large part by GspB, a high-molec

181 Interaction of Mfa fimbriae with S. gordonii is necessary to initiate signalling through Cdh

182 A and CylB system by the alpha-haemolytic S. gordonii is presented.

183 Like wild-type S. gordonii, isogenic mutants with mutations in antigen I/I

184 Mutants of S. gordonii lacking components of the CiaRH, ComDE, or VicR

185 etence sigma factor, were found preceding S. gordonii late responsive genes.

186 (P < .005) but failed to protect against S. gordonii (<30% protection).

187 d primer extension analyses revealed that S. gordonii luxS is monocistronic.

188 An S. gordonii luxS mutant that did not produce AI-2 was const

189 hat the A regions from the two Streptococcus gordonii M5 antigen I/II proteins (SspA and SspB) intera

190 face glycoprotein expressed by Streptococcus gordonii M99 that mediates binding of this organism to h

191 -glycosyltransferase GtfA/B of Streptococcus gordonii modifies the Ser/Thr-rich repeats of adhesin.

192 trongly (10- to 100-fold) up-regulated in S. gordonii monocultures after 3 h of growth when exogenous

193 The oral commensal Streptococcus gordonii must adapt to constantly fluctuating and often

194 d to be coupled with the induction of the S. gordonii natural competence system.

195 ted singly, S. mutans always out-competed S. gordonii on the teeth, independent of diet, strain of S.

196 2 days before inoculation with Streptococcus gordonii or Staphylococcus aureus.

197 ) S. sanguis than with PAAP(-) Streptococcus gordonii or type II collagen, suggesting an Ag-specific

198 the crucial role AbpB appears to play in S. gordonii oral colonization.

199 stimulated with oral commensal Streptococcus gordonii, oral pathogens Porphyromonas gingivalis and Ac

200 e Streptococcus sanguinis than Streptococcus gordonii organisms are consistently isolated from the sa

201 hus, Hsa confers a selective advantage to S. gordonii over S. sanguinis in competitive binding to sHA

202 the high degree of similarity between the S. gordonii paralogues, analysis of SecA-SecA2 chimeras ind

203 The S. gordonii PepV gene is homologous to the PepV gene family

204 Overall, F. nucleatum and S. gordonii perturbed the gingival epithelial cell transcri

205 The ADS of the oral bacterium Streptococcus gordonii plays major roles in physiologic homeostasis, a

206 Contact with S. gordonii propagates a tyrosine phosphorylation-dependent

207 ls Streptococcus sanguinis and Streptococcus gordonii release DNA in a process induced by pyruvate ox

208 We have investigated genes of S. gordonii required to support a heterotypic biofilm commu

209 Comparison of isogenic pairs of S. gordonii revealed a requirement for several surface prot

210 Zymographic analysis of wild-type S. gordonii revealed peptidoglycan hydrolase activities wit

211 tion, or presence/absence of mutations of S. gordonii's abpA and gtfG genes known to negatively or po

212 Probe SSA-3 hybridized to DNA from S. gordonii, S. mitis, S. oralis, S. parasanguinis, and S.

213 UVEC was exhibited by selected strains of S. gordonii, S. sanguis, S. mutans, S. mitis, and S. oralis

214 ius (two strains); and one strain each of S. gordonii, S. sanguis, S. sobrinus, and S. vestibularis.

215 h high homology to that of the Streptococcus gordonii ScaR binding domain.

216 Comparison of the S. gordonii SecA and SecA2 proteins in vitro revealed that

217 biochemical methods to assess whether the S. gordonii SecA2 functions similarly to SecA.

218 To test this theory, S. gordonii secY2, asp4, and asp5 were co-expressed in Esch

219 In biofilms, S. gordonii selectively expresses the msrA gene.

220 n Porphyromonas gingivalis and Streptococcus gordonii serves to constrain development of dual species

221 n peroxide in solution above a Streptococcus gordonii (Sg) bacterial biofilm was studied in real time

222 65 +/- 10 muM H2O2 produced by Streptococcus gordonii (Sg) in a simulated biofilm at 50 mum above its

223 commensal streptococci such as Streptococcus gordonii (Sg).

224 Streptococcus gordonii (Sg)/S. oralis (So)/S. sanguinis (Ss) and Sg/Fu

225 By contrast, an hsa-deficient mutant of S. gordonii showed significantly reduced binding and compet

226 Streptococcus gordonii shows promise as a live mucosal vaccine vector

227 rdonii DLl than of streptomycin-resistant S. gordonii SK12 from the hearts of animals coinfected with

228 e, while the other two strains, including S. gordonii SK12, caused minimal or no disease.

229 The S. gordonii SspA and SspB polypeptides mediated higher bind

230 thin the C-terminal portion of Streptococcus gordonii SspB (AgI/II) is bound by Porphyromonas gingiva

231 treptococcus mutans AgI/II and Streptococcus gordonii SspB in their interaction with the SRCRs.

232 e.g., Veillonella parvula and Streptococcus gordonii, stimulated higher levels of ROS and NET releas

233 Each S. gordonii strain aggregated with human platelets and boun

234 However, Streptococcus gordonii strain M99 encodes SecA and SecY homologues tha

235 The gspB-secY2A2 locus of Streptococcus gordonii strain M99 encodes the platelet-binding glycopr

236 Platelet binding by Streptococcus gordonii strain M99 is dependent on expression of the ce

237 Platelet binding by Streptococcus gordonii strain M99 is mediated predominantly by the cel

238 Platelet binding by Streptococcus gordonii strain M99 is predominantly mediated by the 286

239 Platelet binding by Streptococcus gordonii strain M99 is strongly correlated with the expr

240 imately 1.5 x 10(9) CFU of SP204(1-1), an S. gordonii strain not bearing vaccine antigens.

241 Adhesin-mediated binding of each S. gordonii strain to PMNs also triggered phagocytosis.

242 On the contrary, genomic islands of S. gordonii strains contain additional copies of comCDE quo

243 -rich surface glycoproteins of Streptococcus gordonii strains M99 and Challis, respectively, that med

244 nce among seven representative Streptococcus gordonii strains were observed by using the rat model of

245 , one of which was exclusively present in S. gordonii strains.

246 , Corynebacterium matruchotii, Streptococcus gordonii, Streptococcus cristatus, Capnocytophaga gingiv

247 y polypeptides from strains of Streptococcus gordonii, Streptococcus intermedius and Streptococcus mu

248 reus, Streptococcus sanguinis, Streptococcus gordonii, Streptococcus oralis, and Streptococcus pneumo

249 ng of accessory Sec systems in Streptococcus gordonii, Streptococcus parasanguinis, Mycobacterium sme

250 closely related oral species, Streptococcus gordonii, Streptococcus sanguinis, and cariogenic Strept

251 produced by the oral bacterium Streptococcus gordonii, suggesting the potential for cross-feeding in

252 t also glucosyltransferase G (Gtf-G) from S. gordonii supernatants.

253 rough a cell wall glycoprotein termed GspB ('gordonii surface protein B').

254 ly on the sgc protease knockout mutant of S. gordonii than on the parent biofilms.

255 nes developed more abundant biofilms with S. gordonii than the parental strain developed.

256 cascade dominantly control phenotypes of S. gordonii that are critical to colonization, persistence,

257 ogous surface glycoproteins of Streptococcus gordonii that bind sialic acid moieties on platelet memb

258 uorescence levels 20-fold higher than did S. gordonii that had not been incubated with V. atypica.

259 nization of smooth surfaces by Streptococcus gordonii that incorporates the nutrient flux that occurs

260 e-rich glycoprotein adhesin of Streptococcus gordonii that is exported to the bacterial surface by th

261 In the gram-positive Streptococcus gordonii, the ability to form disulfide bonds affected a

262 In Streptococcus gordonii, the SRR glycoprotein GspB has a 90-residue ami

263 that P. gingivalis adheres to Streptococcus gordonii through interaction of the minor fimbrial antig

264 An isolated S. gordonii::Tn917-lac biofilm-defective mutant contained a

265 Investigation of an S. gordonii::Tn917-lac biofilm-defective mutant isolated by

266 An S. gordonii::Tn917-lac biofilm-defective mutant was isolate

267 trast, did not significantly compete with S. gordonii to adhere.

268 d that attachment of A. naeslundii and of S. gordonii to glass flowcells was enhanced by a salivary c

269 sp5 are necessary for optimal adhesion of S. gordonii to glycoproteins gp340 and fibronectin, known H

270 le nutrient showed that V. atypica caused S. gordonii to increase expression of a PamyB-'gfp transcri

271 I/II family proteins) can bind Streptococcus gordonii to other oral bacteria and also to salivary agg

272 constraint against S. sanguinis, enabling S. gordonii to persist within the oral cavity, despite the

273 huttle plasmid, plasmid DNA transfer from S. gordonii to S. mutans was observed in a CSP and mutacin

274 3 also resulted in an impaired ability of S. gordonii to secrete GspB.

275 ution of GspB and Hsa to the adherence of S. gordonii to selected glycoproteins.

276 Thus, the ability of S. gordonii to survive in PMNs following adhesin-mediated p

277 The capacity of S. gordonii to synthesize arginine was assessed using a che

278 of pioneer organisms, such as Streptococcus gordonii, to tooth surfaces.

279 icated by transformation frequencies, the S. gordonii transcriptome was analyzed at various time poin

280 Comparison of CSP-induced S. gordonii transcriptomes to results published for Strepto

281 In Streptococcus gordonii, transport of the serine-rich glycoprotein GspB

282 emonstrated an increased DNA release from S. gordonii upon addition of the partially purified mutacin

283 ing aerotolerant ones, such as Streptococcus gordonii, use pyruvate dehydrogenase to decarboxylate py

284 S. sanguinis and S. gordonii used oxygen availability and the differential p

285 o simulate pioneer colonization of teeth, S. gordonii V288 was incubated with sHA for 4 h in THB with

286 rmation, a plasmid integration library of S. gordonii V288 was used.

287 lysis, the entire accessory Sec system of S. gordonii was expressed in Escherichia coli.

288 maximum AI-2 induction was detected when S. gordonii was grown in the presence of serum and carbonat

289 s, Streptococcus sanguinis, or Streptococcus gordonii was investigated using flow cell devices that a

290 Biofilm formation by S. gordonii was observed to be influenced by the presence o

291 expression of argC, argG, and pyrA(b) in S. gordonii was partially up-regulated although arginine wa

292 in a dose-dependent manner while that of S. gordonii was unaffected.

293 In coaggregation assays, SspB from S. gordonii was unique in mediating coaggregation with only

294 ncoding a major autolysin from Streptococcus gordonii, was identified and characterized.

295 te disulfide bond formation in Streptococcus gordonii, we identified five putative TDORs from the seq

296 o the platelet adhesin GspB in Streptococcus gordonii, were identified.

297 sis, the 20-kDa AbpA protein is unique to S. gordonii, whereas the 82-kDa AbpB protein appears to sha

298 rast, type 1 fimbriated A. naeslundii and S. gordonii, which bound purified proline-rich proteins (PR

299 both species and well-defined mutants of S. gordonii with interrupted abpA and gtfG genes were studi

300 Furthermore, communities of S. gordonii with P. gingivalis or with A. actinomycetemcomi