ライフサイエンスコーパス: granulation

1 the surface of the Sun-a phenomenon known as granulation.

2 c myelocytes that showed abnormal basophilic granulation.

3 poor re-epithelialization, angiogenesis and granulation.

4 s of key parameters such as inflammation and granulation.

5 model of CSF outflow across human arachnoid granulations (AGs) as an approximation of in vivo condit

6 tion (2-3 weeks after insertion to allow for granulation and fixation of viscera) and formation of th

7 ewly grown microvessels resembled vessels of granulation and neoplastic tissue in many aspects.

8 thelialization, contraction and formation of granulation and scar tissue.

9 The pattern and amount of collagen-rich granulation bed tissue, manufactured by fibroblasts, was

10 on, interstitial fibrosis, desquamation, and granulation by an experienced pulmonary pathologist.

11 e particles enhanced reepithelialization and granulation, by 2- and 3-fold respectively, when compare

12 ated with respect to their botanical origin, granulation, colour and sensory properties.

13 Granulation, colour, and sensory properties of honey wer

14 se in wound healing (reepithelialization and granulation) compared to the wild-type control.

15 as longer in subjects with lesser degrees of granulation/connective tissue deposition (fibroblastic f

16 res of IPF, i.e., fibrosis, cellularity, the granulation/connective tissue deposition, and the total

17 Secretion occurs through de-granulation during post-infective development, and the p

18 aphy, we also directly observe dilatancy and granulation effects, which lead to fracture above a crit

19 a model using human arachnoid membrane with granulations for the study of conditions such as Alzheim

20 nflammation, epidermis re-epithelialization, granulation formation, and proper wound healing in mice.

21 ions on skull radiographs, seen as arachnoid granulations fovea in CT.

22 Fibroblasts of healthy and granulation gingiva are phenotypically heterogeneous wit

23 ferences may affect activities of normal and granulation gingiva.

24 uch as cell proliferation, angiogenesis, and granulation growth were investigated.

25 defies typically postulated requirements for granulation in biotechnology, i.e., the need for hydrody

26 ements can be used to probe the processes of granulation in concentrated colloidal suspensions.

27 o the mouse Ren1d-null background, restoring granulation in juxtaglomerular cells.

28 er in the arachnoid membrane adjacent to the granulations, in addition to the flow through the AGs.

29 The brain's arachnoid membrane with granulations is an important biological barrier whose re

30 tion, and that it reduces vascularization of granulation issue, probably through disabling of the sho

31 te granulocytic differentiation with profuse granulation, mature, clumped chromatin, and myeloperoxid

32 Anterior lamellar repair was by granulation (n = 2), local skin flaps (n = 3), or skin g

33 red by vacuum drying, freeze drying or spray granulation of aqueous mixtures of omega-3 oil and beta-

34 The Fourier power of granulation on a star's surface correlates physically wi

35 ibrations can be used to control jamming and granulation, resulting in a flowable fluid.

36 variations on timescales of hours arise from granulation, then such variations should correlate with

37 ocardium, acutely cryoinjured myocardium, or granulation tissue (6 days after injury).

38 sis, were occluded with mucus (syngeneic) or granulation tissue (allogeneic).

39 ounds curetted on day 5 were 23% filled with granulation tissue 1 day later and 99% filled 3 days lat

40 Fbln5 is upregulated in the granulation tissue 14 days after full-thickness wounding

41 We identified wound granulation tissue 3 days post-CD in both strains, albei

42 afts demonstrated significantly less lumenal granulation tissue 35.3%+/-32 than the allograft implant

43 roup demonstrated significantly less lumenal granulation tissue 48.3%+/-23.7 when compared with the i

44 histologic response (three of four with >95% granulation tissue and <5% necrosis, one of four with 95

45 the number of myofibroblasts present in the granulation tissue and accelerates wound closure and con

46 inases are rapidly induced in the dermis and granulation tissue and at the leading edge of the epider

47 alse-positive findings due to enhancement of granulation tissue and benign breast tissue remain limit

48 , cryopyrin, and caspase-1, localized to the granulation tissue and cardiomyocytes bordering the infa

49 reases in blood flow and permeability in rat granulation tissue and corresponding vascular changes in

50 n preventing the anisotropic organization of granulation tissue and delaying wound healing.

51 wiss mice resulted in a large stimulation of granulation tissue and fibrosis at the site of injection

52 ontrol), especially in cells re-epithelizing granulation tissue and in mucosa in proximity to the ulc

53 Additionally, cells in the granulation tissue and keratinocytes at wound edges show

54 resorption, and extensive inflammation with granulation tissue and polymorphonuclear leukocytes.

55 serve as a "barrier," limiting expansion of granulation tissue and protecting the noninfarcted myoca

56 ration, and vessel formation to form a thick granulation tissue and re-epithelialization of the wound

57 9.5 were expressed by fibroblasts during the granulation tissue and remodeling phases wound healing.

58 ed transgene expression in myofibroblasts in granulation tissue and responsiveness to transforming gr

59 es of cutaneous wounding resulted in reduced granulation tissue and scarring.

60 ed wound closure, decreased inflammation and granulation tissue area, and normalized mechanical prope

61 Granulation tissue area, vascularity, and IGF1 and EGF r

62 rkable increase in the vascular component in granulation tissue as compared to Ad-LacZ controls.

63 chondrification centers and persisted within granulation tissue at the expanding soft callus front.

64 On postoperative day 7, the thickness of granulation tissue at the graft-wound bed interface was

65 r-BB protein (n = 2) resulted in only modest granulation tissue at the margin, but no significant dif

66 lized in the preliminary matrix organized in granulation tissue before trabecular bone formation in t

67 ross-linked collagenous matrix is formed and granulation tissue cells become apoptotic.

68 and platelet releasate were 14% filled with granulation tissue compared with less than 4% granulatio

69 concept that IL-1Ra modulates MCL-localized granulation tissue components and cytokine production to

70 ing by enhancing basement membrane proteins, granulation tissue components, and angiogenic factors.

71 mulating the M2 macrophages and altering the granulation tissue components.

72 he fibrin inside the chambers is replaced by granulation tissue consisting of new blood vessels, macr

73 is a significant reduction in the extent of granulation tissue deposition and the subsequent formati

74 ing agent, enhancing reepithelialization and granulation tissue deposition by 64+/-5 and 83+/-12% ove

75 in response to injury, resulting in delayed granulation tissue deposition in PKCalpha-/- wounds.

76 analysis showed that epithelium ingrowth and granulation tissue deposition were significantly impaire

77 ithelialization, angiogenesis, inflammation, granulation tissue deposition, and enhanced collagen org

78 , malformed vasculature followed by abundant granulation tissue deposition.

79 thrombus deposition and acute inflammation, granulation tissue development, and ultimately smooth mu

80 repair a 3-day lag occurs between injury and granulation tissue development.

81 Granulation tissue did not form in day 3 wounds, which h

82 exhibited impaired development of functional granulation tissue due to severely reduced differentiati

83 in vessels that developed in sponge-induced granulation tissue during 1 month derived from circulati

84 e is highly induced in dermal fibroblasts of granulation tissue during cutaneous wound repair.

85 the organization and vascularization of the granulation tissue during healing, possibly by modulatin

86 tly stimulates neovascularization within the granulation tissue during the first week of treatment, f

87 y and function in specific cell types in the granulation tissue during the healing process is unknown

88 fter receiving the lower viral dose, cardiac granulation tissue expressed MyoD mRNA and protein, but

89 CTX also reduced dermal granulation tissue fibroblast population increases induc

90 Once granulation tissue filled the wound and invasive angioge

91 The granulation tissue filling the wound during healing also

92 increased keratinocyte migration (7.5-fold), granulation tissue formation (2.8-fold), cell proliferat

93 nsgenic mice and was associated with reduced granulation tissue formation and highly diminished wound

94 imulatory effect of overexpressed activin on granulation tissue formation and reepithelialization of

95 This work directly relates to both granulation tissue formation and regression during wound

96 d cardiomyocytes, while mediating aspects of granulation tissue formation and remodeling.

97 d results in accelerated healing and reduced granulation tissue formation and scarring.

98 into the fibrin-laden wound is critical for granulation tissue formation and subsequent healing.

99 into the fibrin-laden wound is critical for granulation tissue formation and subsequent healing.

100 e, or response to infection, but it promoted granulation tissue formation and suppressed leukocyte ne

101 synthesis or action reduces TGF-beta-induced granulation tissue formation by inhibiting both collagen

102 GA-LL37 NP-treated wounds displayed advanced granulation tissue formation by significant higher colla

103 We initiated local granulation tissue formation either by implanting small

104 to the fibrin matrix significantly increased granulation tissue formation in a dose-dependent manner.

105 sient, role during invasive angiogenesis and granulation tissue formation in a healing wound.

106 on of miR-21 inhibited epithelialization and granulation tissue formation in a rat wound model.

107 onists of alphaVbeta3 specifically inhibited granulation tissue formation in a transient manner durin

108 pendent increase in epithelial migration and granulation tissue formation in both murine and porcine

109 ic blocking of alphavbeta3 function inhibits granulation tissue formation in cutaneous wounds.

110 complete re- epithelialization and profound granulation tissue formation in excisional and incisiona

111 Granulation tissue formation in punch wounds of juvenile

112 Lovastatin (5 microM, 8 d) reduced granulation tissue formation in the wound chambers by 64

113 the myocardial scar, suggesting expansion of granulation tissue formation into the noninfarcted terri

114 Granulation tissue formation is a critical step in infar

115 Granulation tissue formation is an example of new tissue

116 During early granulation tissue formation of wound repair, new capill

117 Thus, granulation tissue formation resumed promptly and indepe

118 ial cell chemotaxis, vascular sprouting, and granulation tissue formation upon skin injury, these act

119 ared to their wild-type littermates although granulation tissue formation was nonhomogeneous and ther

120 During granulation tissue formation, alphaVbeta3 was expressed

121 g was induced by rapid re-epithelialization, granulation tissue formation, and accompanied by angioge

122 uced, and careful analysis of wound closure, granulation tissue formation, and angiogenesis revealed

123 with compromised wound closure, insufficient granulation tissue formation, and blunted induction of M

124 fibroblast activation is a limiting step of granulation tissue formation, and continued cell stimula

125 t mice show suppressed inflammation, delayed granulation tissue formation, and markedly reduced colla

126 g delayed contraction, decreased and delayed granulation tissue formation, and reduced new blood vess

127 Wound closure, reepithelialization, granulation tissue formation, and remodeling were delaye

128 ed to accelerate wound re-epithelialization, granulation tissue formation, and synergistically improv

129 telets and macrophages, is not important for granulation tissue formation, and that it reduces vascul

130 are known to be associated with significant granulation tissue formation, and this property provides

131 l-thickness, cutaneous wounds, with enhanced granulation tissue formation, angiogenesis, cell prolife

132 The rate of granulation tissue formation, based on the time to 76-10

133 PO and observed dose-dependent inhibition of granulation tissue formation, consistent with an importa

134 with reepithelialization and is followed by granulation tissue formation, including neutrophil and m

135 hese studies show that re-epithelialization, granulation tissue formation, including the establishmen

136 ssociated with a proangiogenic effect during granulation tissue formation.

137 ridge formation, decreased inflammation, and granulation tissue formation.

138 ctivation might be the rate-limiting step in granulation tissue formation.

139 nduced in peri-infarct cardiomyocytes during granulation tissue formation.

140 cantly accelerated, resulting in the limited granulation tissue formation.

141 mal and steroid-impaired pigs, CRT increased granulation tissue formation.

142 is study provided histological evidence that granulation tissue forming under clinically exposed and

143 In 14 and 21 d incised wounds and in chronic granulation tissue from nonhealing ulcers there was stro

144 sions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially conj

145 ranulation tissue compared with less than 4% granulation tissue in control wounds.

146 Furthermore, granulation tissue in fibrinogen-deficient mice failed t

147 at in wild-type mice, the early formation of granulation tissue in fibrinogen-deficient mice was edem

148 roximately 1600 mum within wound (neodermis)/granulation tissue in lesions made on the skin of mice.

149 by topical application of VEGF and FGF-2 to granulation tissue in skin chambers, and 2) suramin, a c

150 is caused by expansion of microvascular-rich granulation tissue in some locations and collagen-rich s

151 backs of Sprague-Dawley rats and 1 wk later, granulation tissue in the chamber was exposed twice dail

152 Some patients developed granulation tissue in the larynx, urethra, lacrimal duct

153 wounds, which corresponds with the increased granulation tissue in these wounds.

154 p-regulated in newly formed blood vessels of granulation tissue in vivo.

155 The prerequisites for granulation tissue induction are not known but hypotheti

156 ests angiogenesis with transformation of the granulation tissue into a scar.

157 ocal angiogenesis, and limiting expansion of granulation tissue into the noninfarcted area.

158 accelerated replacement of cardiomyocytes by granulation tissue leading to a thin mature scar at 14 d

159 processes including re-epithelialization and granulation tissue matrix deposition.

160 Vbeta3 showed little or no expression in the granulation tissue microvasculature.

161 Granulation tissue myofibroblasts and infiltrating macro

162 e recipient airway demonstrated less lumenal granulation tissue obstruction and better preservation o

163 Four patients with granulation tissue occluding the airway were treated wit

164 dy, we show that CCN3 is highly expressed in granulation tissue of cutaneous wounds 5-7 days after in

165 ntron was expressed in myofibroblasts within granulation tissue of cutaneous wounds in a pattern that

166 showed that, similar to TSP1-null mice, the granulation tissue of double-null mice was not excessive

167 margins of human keloid samples, and in the granulation tissue of newly deposited ECM in a mouse mod

168 ransgene expression in myofibroblasts within granulation tissue of skin wounds.

169 round the healing margins and throughout the granulation tissue of superficial ulcerative wounds.

170 cells of adjacent hair follicles, and to the granulation tissue of the wounds.

171 in processes involved in development of the granulation tissue of wounds, but little is known about

172 onia without histological evidence of either granulation tissue or pulmonary fibrosis.

173 PDGF B-chain did not decrease the extent of granulation tissue or vascular lesion formation, and tha

174 e healing (24days) and exhibited accelerated granulation tissue production, epithelial maturation, an

175 iferation, in vivo engraftment, experimental granulation tissue reconstitution, and tissue vascularit

176 ptozotocin-induced diabetic rats to elicit a granulation tissue response and to collect acute wound f

177 ll surgical sponges to elicit a foreign body granulation tissue response, or by ligating the left com

178 hol sponges were implanted to elicit a naive granulation tissue response, removed at defined time poi

179 N-terminal domain is a key regulator of the granulation tissue response, with important implications

180 pyogenic granuloma is an exuberant growth of granulation tissue secondary to irritation.

181 ponge implants in Flk-1(LacZ) knock-in mice, granulation tissue showed many more LacZ-positive cells

182 ells/blood vessel lumen, M2 macrophages, and granulation tissue size without compromising the mechani

183 Hypoxia peaked in the granulation tissue stage at day 4 and correlated with in

184 In the tuberculous granulation tissue surrounding caseous and liquefied pul

185 terized by decreased contraction and reduced granulation tissue thickness.

186 preparation, a palatal mini-flap was raised, granulation tissue was eliminated by means of ultrasonic

187 tion, generation of thick, well-vascularized granulation tissue was enhanced, in parallel with increa

188 hire pigs and harvested at various times, no granulation tissue was observed before day 4.

189 In contrast, granulation tissue was observed in wounds receiving fibr

190 nt of inflammatory macrophages, formation of granulation tissue with angiogenesis, and finally tissue

191 The subacute response exhibited granulation tissue with early fibrous encapsulation (pan

192 unctional enzyme expression by repair cells (granulation tissue) growing into the gap.

193 latelet and fibrin deposition, inflammation, granulation tissue, and finally, fibrous encapsulation.

194 mages correlated with liquefaction necrosis, granulation tissue, and tumor.

195 g wound re-epithelialization, formulation of granulation tissue, and vascularization.

196 Day 4 wounds were 3% filled with granulation tissue, day 5 wounds 48% filled, and day 7 w

197 of TGF beta leading to enhanced formation of granulation tissue, even in the absence of obvious infec

198 istology showed channel remnants composed of granulation tissue, fibrosis, and new vessels (NV).

199 ion (loss of respiratory epithelium, luminal granulation tissue, lymphocytic tracheitis) with increas

200 The rates of granulation tissue, otalgia, and facial palsy were 90.9%

201 is, early wound provisional matrix, and late granulation tissue, respectively.

202 monocyte infiltration/giant cell formation (granulation tissue, the intimal and subintimal synovial

203 alpha-smooth muscle actin and are present in granulation tissue, where they are responsible for wound

204 activation of alpha-SMA in myofibroblasts in granulation tissue.

205 d replacement of injured cardiomyocytes with granulation tissue.

206 of alpha-SMA expression in myofibroblasts in granulation tissue.

207 d replacement of injured cardiomyocytes with granulation tissue.

208 in myofibroblasts and smooth muscle cells of granulation tissue.

209 tion of necrotic tissue and replacement with granulation tissue.

210 nificantly inhibited in vivo angiogenesis in granulation tissue.

211 f inducible nitric oxide synthase protein in granulation tissue.

212 ient has chronic refractory otorrhea and ear granulation tissue.

213 ermal wound margin and over fibronectin-rich granulation tissue.

214 skin wounds and impaired angiogenesis in the granulation tissue.

215 gnificantly reduced vascularity of the wound granulation tissue.

216 growth factor, is highly expressed in dermal granulation tissue.

217 emonstrated peripheral flow at US because of granulation tissue.

218 rregularly organized and highly vascularized granulation tissue.

219 th the abnormal collagen organization in the granulation tissue.

220 d associated with the formation of abdominal granulation tissue.

221 epithelialization and increased formation of granulation tissue.

222 placement by a thin layer of highly vascular granulation tissue.

223 necrotic areas, connective tissue stroma or granulation tissue.

224 tion of fibroblasts, and angiogenesis in the granulation tissue.

225 cterized by more inflammatory, necrotic, and granulation tissue.

226 ement of an intrauterine device, and vaginal granulation tissue.

227 g the formation of new arterioles within the granulation tissue.

228 r, increasingly in antigen-negative areas of granulation tissue.

229 d regulates their cytokine production in the granulation tissue.

230 elimination of tumor cells and formation of granulation tissue.

231 ar density of MRL-MSC-generated experimental granulation tissue.

232 ce re-epithelialization and the formation of granulation tissue.

233 lar weight S100A7 in human wound exudate and granulation tissue.

234 tor (VEGF), Flk1, and VE-cadherin in ECs and granulation tissues (GTs) of full-thickness wounds.

235 ts show that Cyr61 is inducibly expressed in granulation tissues after wounding and that Cyr61 activa

236 of active wounds of living T1D subjects, and granulation tissues from mice with streptozotocin-induce

237 r, specifically with the transition from the granulation to the remodeling phases of the wound healin

238 Spray granulation was found to be the superior drying method f

239 heric velocities are dominated by convective granulation (which has been considered before for spicul

240 c rises in viscosity, leading to jamming and granulation, with increasing shear rate.

241 genic determination gene, MyoD, into cardiac granulation (wound repair) tissue.