ライフサイエンスコーパス: granulation tissue

1 tion of fibroblasts, and angiogenesis in the granulation tissue.

2 f inducible nitric oxide synthase protein in granulation tissue.

3 ermal wound margin and over fibronectin-rich granulation tissue.

4 skin wounds and impaired angiogenesis in the granulation tissue.

5 gnificantly reduced vascularity of the wound granulation tissue.

6 growth factor, is highly expressed in dermal granulation tissue.

7 emonstrated peripheral flow at US because of granulation tissue.

8 epithelialization and increased formation of granulation tissue.

9 rregularly organized and highly vascularized granulation tissue.

10 th the abnormal collagen organization in the granulation tissue.

11 d associated with the formation of abdominal granulation tissue.

12 placement by a thin layer of highly vascular granulation tissue.

13 necrotic areas, connective tissue stroma or granulation tissue.

14 cterized by more inflammatory, necrotic, and granulation tissue.

15 ement of an intrauterine device, and vaginal granulation tissue.

16 g the formation of new arterioles within the granulation tissue.

17 r, increasingly in antigen-negative areas of granulation tissue.

18 d regulates their cytokine production in the granulation tissue.

19 ce re-epithelialization and the formation of granulation tissue.

20 elimination of tumor cells and formation of granulation tissue.

21 ar density of MRL-MSC-generated experimental granulation tissue.

22 lar weight S100A7 in human wound exudate and granulation tissue.

23 activation of alpha-SMA in myofibroblasts in granulation tissue.

24 d replacement of injured cardiomyocytes with granulation tissue.

25 of alpha-SMA expression in myofibroblasts in granulation tissue.

26 d replacement of injured cardiomyocytes with granulation tissue.

27 ient has chronic refractory otorrhea and ear granulation tissue.

28 in myofibroblasts and smooth muscle cells of granulation tissue.

29 tion of necrotic tissue and replacement with granulation tissue.

30 nificantly inhibited in vivo angiogenesis in granulation tissue.

31 ounds curetted on day 5 were 23% filled with granulation tissue 1 day later and 99% filled 3 days lat

32 Fbln5 is upregulated in the granulation tissue 14 days after full-thickness wounding

33 We identified wound granulation tissue 3 days post-CD in both strains, albei

34 afts demonstrated significantly less lumenal granulation tissue 35.3%+/-32 than the allograft implant

35 roup demonstrated significantly less lumenal granulation tissue 48.3%+/-23.7 when compared with the i

36 ocardium, acutely cryoinjured myocardium, or granulation tissue (6 days after injury).

37 ts show that Cyr61 is inducibly expressed in granulation tissues after wounding and that Cyr61 activa

38 sis, were occluded with mucus (syngeneic) or granulation tissue (allogeneic).

39 histologic response (three of four with >95% granulation tissue and <5% necrosis, one of four with 95

40 the number of myofibroblasts present in the granulation tissue and accelerates wound closure and con

41 inases are rapidly induced in the dermis and granulation tissue and at the leading edge of the epider

42 alse-positive findings due to enhancement of granulation tissue and benign breast tissue remain limit

43 , cryopyrin, and caspase-1, localized to the granulation tissue and cardiomyocytes bordering the infa

44 reases in blood flow and permeability in rat granulation tissue and corresponding vascular changes in

45 n preventing the anisotropic organization of granulation tissue and delaying wound healing.

46 wiss mice resulted in a large stimulation of granulation tissue and fibrosis at the site of injection

47 ontrol), especially in cells re-epithelizing granulation tissue and in mucosa in proximity to the ulc

48 Additionally, cells in the granulation tissue and keratinocytes at wound edges show

49 resorption, and extensive inflammation with granulation tissue and polymorphonuclear leukocytes.

50 serve as a "barrier," limiting expansion of granulation tissue and protecting the noninfarcted myoca

51 ration, and vessel formation to form a thick granulation tissue and re-epithelialization of the wound

52 9.5 were expressed by fibroblasts during the granulation tissue and remodeling phases wound healing.

53 ed transgene expression in myofibroblasts in granulation tissue and responsiveness to transforming gr

54 es of cutaneous wounding resulted in reduced granulation tissue and scarring.

55 latelet and fibrin deposition, inflammation, granulation tissue, and finally, fibrous encapsulation.

56 mages correlated with liquefaction necrosis, granulation tissue, and tumor.

57 g wound re-epithelialization, formulation of granulation tissue, and vascularization.

58 ed wound closure, decreased inflammation and granulation tissue area, and normalized mechanical prope

59 Granulation tissue area, vascularity, and IGF1 and EGF r

60 rkable increase in the vascular component in granulation tissue as compared to Ad-LacZ controls.

61 chondrification centers and persisted within granulation tissue at the expanding soft callus front.

62 On postoperative day 7, the thickness of granulation tissue at the graft-wound bed interface was

63 r-BB protein (n = 2) resulted in only modest granulation tissue at the margin, but no significant dif

64 lized in the preliminary matrix organized in granulation tissue before trabecular bone formation in t

65 ross-linked collagenous matrix is formed and granulation tissue cells become apoptotic.

66 and platelet releasate were 14% filled with granulation tissue compared with less than 4% granulatio

67 concept that IL-1Ra modulates MCL-localized granulation tissue components and cytokine production to

68 ing by enhancing basement membrane proteins, granulation tissue components, and angiogenic factors.

69 mulating the M2 macrophages and altering the granulation tissue components.

70 he fibrin inside the chambers is replaced by granulation tissue consisting of new blood vessels, macr

71 Day 4 wounds were 3% filled with granulation tissue, day 5 wounds 48% filled, and day 7 w

72 is a significant reduction in the extent of granulation tissue deposition and the subsequent formati

73 ing agent, enhancing reepithelialization and granulation tissue deposition by 64+/-5 and 83+/-12% ove

74 in response to injury, resulting in delayed granulation tissue deposition in PKCalpha-/- wounds.

75 analysis showed that epithelium ingrowth and granulation tissue deposition were significantly impaire

76 ithelialization, angiogenesis, inflammation, granulation tissue deposition, and enhanced collagen org

77 , malformed vasculature followed by abundant granulation tissue deposition.

78 thrombus deposition and acute inflammation, granulation tissue development, and ultimately smooth mu

79 repair a 3-day lag occurs between injury and granulation tissue development.

80 Granulation tissue did not form in day 3 wounds, which h

81 exhibited impaired development of functional granulation tissue due to severely reduced differentiati

82 in vessels that developed in sponge-induced granulation tissue during 1 month derived from circulati

83 e is highly induced in dermal fibroblasts of granulation tissue during cutaneous wound repair.

84 the organization and vascularization of the granulation tissue during healing, possibly by modulatin

85 tly stimulates neovascularization within the granulation tissue during the first week of treatment, f

86 y and function in specific cell types in the granulation tissue during the healing process is unknown

87 of TGF beta leading to enhanced formation of granulation tissue, even in the absence of obvious infec

88 fter receiving the lower viral dose, cardiac granulation tissue expressed MyoD mRNA and protein, but

89 CTX also reduced dermal granulation tissue fibroblast population increases induc

90 istology showed channel remnants composed of granulation tissue, fibrosis, and new vessels (NV).

91 Once granulation tissue filled the wound and invasive angioge

92 The granulation tissue filling the wound during healing also

93 increased keratinocyte migration (7.5-fold), granulation tissue formation (2.8-fold), cell proliferat

94 nsgenic mice and was associated with reduced granulation tissue formation and highly diminished wound

95 imulatory effect of overexpressed activin on granulation tissue formation and reepithelialization of

96 This work directly relates to both granulation tissue formation and regression during wound

97 d cardiomyocytes, while mediating aspects of granulation tissue formation and remodeling.

98 d results in accelerated healing and reduced granulation tissue formation and scarring.

99 into the fibrin-laden wound is critical for granulation tissue formation and subsequent healing.

100 into the fibrin-laden wound is critical for granulation tissue formation and subsequent healing.

101 e, or response to infection, but it promoted granulation tissue formation and suppressed leukocyte ne

102 synthesis or action reduces TGF-beta-induced granulation tissue formation by inhibiting both collagen

103 GA-LL37 NP-treated wounds displayed advanced granulation tissue formation by significant higher colla

104 We initiated local granulation tissue formation either by implanting small

105 to the fibrin matrix significantly increased granulation tissue formation in a dose-dependent manner.

106 sient, role during invasive angiogenesis and granulation tissue formation in a healing wound.

107 on of miR-21 inhibited epithelialization and granulation tissue formation in a rat wound model.

108 onists of alphaVbeta3 specifically inhibited granulation tissue formation in a transient manner durin

109 pendent increase in epithelial migration and granulation tissue formation in both murine and porcine

110 ic blocking of alphavbeta3 function inhibits granulation tissue formation in cutaneous wounds.

111 complete re- epithelialization and profound granulation tissue formation in excisional and incisiona

112 Granulation tissue formation in punch wounds of juvenile

113 Lovastatin (5 microM, 8 d) reduced granulation tissue formation in the wound chambers by 64

114 the myocardial scar, suggesting expansion of granulation tissue formation into the noninfarcted terri

115 Granulation tissue formation is a critical step in infar

116 Granulation tissue formation is an example of new tissue

117 During early granulation tissue formation of wound repair, new capill

118 Thus, granulation tissue formation resumed promptly and indepe

119 ial cell chemotaxis, vascular sprouting, and granulation tissue formation upon skin injury, these act

120 ared to their wild-type littermates although granulation tissue formation was nonhomogeneous and ther

121 During granulation tissue formation, alphaVbeta3 was expressed

122 g was induced by rapid re-epithelialization, granulation tissue formation, and accompanied by angioge

123 uced, and careful analysis of wound closure, granulation tissue formation, and angiogenesis revealed

124 with compromised wound closure, insufficient granulation tissue formation, and blunted induction of M

125 fibroblast activation is a limiting step of granulation tissue formation, and continued cell stimula

126 t mice show suppressed inflammation, delayed granulation tissue formation, and markedly reduced colla

127 g delayed contraction, decreased and delayed granulation tissue formation, and reduced new blood vess

128 Wound closure, reepithelialization, granulation tissue formation, and remodeling were delaye

129 ed to accelerate wound re-epithelialization, granulation tissue formation, and synergistically improv

130 telets and macrophages, is not important for granulation tissue formation, and that it reduces vascul

131 are known to be associated with significant granulation tissue formation, and this property provides

132 l-thickness, cutaneous wounds, with enhanced granulation tissue formation, angiogenesis, cell prolife

133 The rate of granulation tissue formation, based on the time to 76-10

134 PO and observed dose-dependent inhibition of granulation tissue formation, consistent with an importa

135 with reepithelialization and is followed by granulation tissue formation, including neutrophil and m

136 hese studies show that re-epithelialization, granulation tissue formation, including the establishmen

137 ssociated with a proangiogenic effect during granulation tissue formation.

138 ridge formation, decreased inflammation, and granulation tissue formation.

139 ctivation might be the rate-limiting step in granulation tissue formation.

140 nduced in peri-infarct cardiomyocytes during granulation tissue formation.

141 cantly accelerated, resulting in the limited granulation tissue formation.

142 mal and steroid-impaired pigs, CRT increased granulation tissue formation.

143 is study provided histological evidence that granulation tissue forming under clinically exposed and

144 In 14 and 21 d incised wounds and in chronic granulation tissue from nonhealing ulcers there was stro

145 of active wounds of living T1D subjects, and granulation tissues from mice with streptozotocin-induce

146 unctional enzyme expression by repair cells (granulation tissue) growing into the gap.

147 tor (VEGF), Flk1, and VE-cadherin in ECs and granulation tissues (GTs) of full-thickness wounds.

148 sions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially conj

149 ranulation tissue compared with less than 4% granulation tissue in control wounds.

150 Furthermore, granulation tissue in fibrinogen-deficient mice failed t

151 at in wild-type mice, the early formation of granulation tissue in fibrinogen-deficient mice was edem

152 roximately 1600 mum within wound (neodermis)/granulation tissue in lesions made on the skin of mice.

153 by topical application of VEGF and FGF-2 to granulation tissue in skin chambers, and 2) suramin, a c

154 is caused by expansion of microvascular-rich granulation tissue in some locations and collagen-rich s

155 backs of Sprague-Dawley rats and 1 wk later, granulation tissue in the chamber was exposed twice dail

156 Some patients developed granulation tissue in the larynx, urethra, lacrimal duct

157 wounds, which corresponds with the increased granulation tissue in these wounds.

158 p-regulated in newly formed blood vessels of granulation tissue in vivo.

159 The prerequisites for granulation tissue induction are not known but hypotheti

160 ests angiogenesis with transformation of the granulation tissue into a scar.

161 ocal angiogenesis, and limiting expansion of granulation tissue into the noninfarcted area.

162 accelerated replacement of cardiomyocytes by granulation tissue leading to a thin mature scar at 14 d

163 ion (loss of respiratory epithelium, luminal granulation tissue, lymphocytic tracheitis) with increas

164 processes including re-epithelialization and granulation tissue matrix deposition.

165 Vbeta3 showed little or no expression in the granulation tissue microvasculature.

166 Granulation tissue myofibroblasts and infiltrating macro

167 e recipient airway demonstrated less lumenal granulation tissue obstruction and better preservation o

168 Four patients with granulation tissue occluding the airway were treated wit

169 dy, we show that CCN3 is highly expressed in granulation tissue of cutaneous wounds 5-7 days after in

170 ntron was expressed in myofibroblasts within granulation tissue of cutaneous wounds in a pattern that

171 showed that, similar to TSP1-null mice, the granulation tissue of double-null mice was not excessive

172 margins of human keloid samples, and in the granulation tissue of newly deposited ECM in a mouse mod

173 ransgene expression in myofibroblasts within granulation tissue of skin wounds.

174 round the healing margins and throughout the granulation tissue of superficial ulcerative wounds.

175 cells of adjacent hair follicles, and to the granulation tissue of the wounds.

176 in processes involved in development of the granulation tissue of wounds, but little is known about

177 onia without histological evidence of either granulation tissue or pulmonary fibrosis.

178 PDGF B-chain did not decrease the extent of granulation tissue or vascular lesion formation, and tha

179 The rates of granulation tissue, otalgia, and facial palsy were 90.9%

180 e healing (24days) and exhibited accelerated granulation tissue production, epithelial maturation, an

181 iferation, in vivo engraftment, experimental granulation tissue reconstitution, and tissue vascularit

182 is, early wound provisional matrix, and late granulation tissue, respectively.

183 ptozotocin-induced diabetic rats to elicit a granulation tissue response and to collect acute wound f

184 ll surgical sponges to elicit a foreign body granulation tissue response, or by ligating the left com

185 hol sponges were implanted to elicit a naive granulation tissue response, removed at defined time poi

186 N-terminal domain is a key regulator of the granulation tissue response, with important implications

187 pyogenic granuloma is an exuberant growth of granulation tissue secondary to irritation.

188 ponge implants in Flk-1(LacZ) knock-in mice, granulation tissue showed many more LacZ-positive cells

189 ells/blood vessel lumen, M2 macrophages, and granulation tissue size without compromising the mechani

190 Hypoxia peaked in the granulation tissue stage at day 4 and correlated with in

191 In the tuberculous granulation tissue surrounding caseous and liquefied pul

192 monocyte infiltration/giant cell formation (granulation tissue, the intimal and subintimal synovial

193 terized by decreased contraction and reduced granulation tissue thickness.

194 preparation, a palatal mini-flap was raised, granulation tissue was eliminated by means of ultrasonic

195 tion, generation of thick, well-vascularized granulation tissue was enhanced, in parallel with increa

196 hire pigs and harvested at various times, no granulation tissue was observed before day 4.

197 In contrast, granulation tissue was observed in wounds receiving fibr

198 alpha-smooth muscle actin and are present in granulation tissue, where they are responsible for wound

199 nt of inflammatory macrophages, formation of granulation tissue with angiogenesis, and finally tissue

200 The subacute response exhibited granulation tissue with early fibrous encapsulation (pan