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1 was initially neutrophilic, and later became granulomatous.
2 oni is an opportunistic pathogen that causes granulomatous amoebic encephalitis (GAE), a chronic and
6 rizes the pathology of giant cell arteritis, granulomatous aortitis, and intracerebral varicella zost
7 y produces stroke, giant cell arteritis, and granulomatous aortitis, and it develops after virus reac
11 11 of 11 aortas with pathologically verified granulomatous arteritis, in 1 of 1 cases of nongranuloma
13 ing from mutations in the NOD2 gene, wherein granulomatous arthritis, uveitis, and dermatitis develop
15 delayed-onset combined immune deficiency and granulomatous/autoimmune manifestations (CID-G/AI), prod
17 f an infant with severe IBD characterized by granulomatous colitis and severe perianal disease, we id
18 to identify genetic factors that might cause granulomatous colitis and severe perianal disease, with
19 patients develop other complications such as granulomatous colitis and/or fatal pulmonary fibrosis.
21 hic epilepsy, lymphoma, mast cell tumour and granulomatous colitis; for morphological traits, we repo
23 thymectomy subsequently developed extensive granulomatous destruction of midface structures, palate,
24 unocompromising condition, including chronic granulomatous disease (CGD) (n=4), diabetes mellitus (DM
27 circulating B cells in patients with chronic granulomatous disease (CGD) and those with HIV infection
30 fective neutrophils in patients with chronic granulomatous disease (CGD) cause susceptibility to extr
32 leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal
33 educed in the blood of patients with chronic granulomatous disease (CGD) for reasons and consequences
37 ears of age) often resembles that of chronic granulomatous disease (CGD) in extent and features of co
44 aspergillosis (IA) in patients with chronic granulomatous disease (CGD) is Aspergillus fumigatus fol
49 NADPH oxidase 2 (Nox2)-deficient chronic granulomatous disease (CGD) mice that lack the gp91(phox
50 inhibited oxidase, or isolated from chronic granulomatous disease (CGD) patients and mice, formed mo
53 hosphate (NADPH) oxidase predisposes chronic granulomatous disease (CGD) patients to infection, and a
54 ide (NADPH) oxidase in patients with chronic granulomatous disease (CGD) results in susceptibility to
55 m-negative pathogen in patients with chronic granulomatous disease (CGD), a deficiency in the phagocy
56 r threat for patients suffering from chronic granulomatous disease (CGD), a primary immunodeficiency
57 bacterium that infects patients with chronic granulomatous disease (CGD), a primary immunodeficiency
58 hate oxidase 2 (NOX2) function cause chronic granulomatous disease (CGD), a primary immunodeficiency
60 ing mutations in this enzyme lead to chronic granulomatous disease (CGD), associated with increased s
61 (HSCT) is a successful treatment for chronic granulomatous disease (CGD), but the safety and efficacy
63 ) and lungs of A. fumigatus-infected chronic granulomatous disease (CGD), hydrocortisone-treated, and
72 model, because in mice with X-linked chronic granulomatous disease (X-CGD) that lack oxidase subunits
73 (iPSCs) from a patient with X-linked chronic granulomatous disease (X-CGD), a defect of neutrophil mi
74 In HSPCs from patients with X-linked chronic granulomatous disease (X-CGD), caused by mutations in th
76 Genetic defects in NADPH oxidase (chronic granulomatous disease [CGD]) and corticosteroid-induced
78 this complex have been implicated in chronic granulomatous disease and Crohn's disease, highlighting
80 articularly beneficial in areas with endemic granulomatous disease and may improve clinical managemen
82 abscess formation in a patient with chronic granulomatous disease and review the literature on Phaeo
84 acoronavirus, resulting in a lethal systemic granulomatous disease called feline infectious peritonit
85 ways of host immune cells in tuberculosis, a granulomatous disease caused by the intracellular pathog
88 G mutations associated with autoimmunity and granulomatous disease did not have altered overall diver
99 h compromise p40(phox) function in a chronic granulomatous disease patient, also perturbed class II A
100 fect on endothelial function in NOX2-chronic granulomatous disease patients (-0.9; 95% confidence int
101 d dilatation was not observed in p47-chronic granulomatous disease patients (-1.5%; 95% confidence in
109 SCID), Wiskott-Aldrich syndrome, and chronic granulomatous disease through retrospective, prospective
113 n age 12.7 years; IQR 6.8-17.3) with chronic granulomatous disease were enrolled from June 15, 2003,
114 age quiescence and prevents mTORC1-dependent granulomatous disease with clinical implications for sar
115 efects in oxidase function result in chronic granulomatous disease with hallmark recurrent microbial
116 6PD deficiency can be a phenocopy of chronic granulomatous disease with regard to the cellular and cl
117 ox), p47(phox), p67(phox) (autosomal chronic granulomatous disease), or gp91(phox) (X-linked chronic
118 the phagocyte NADPH oxidase complex (chronic granulomatous disease), severe congenital neutropenia (S
119 us disease), or gp91(phox) (X-linked chronic granulomatous disease), which result in variable product
120 mmatory disease, 15.4%; malabsorption, 5.9%; granulomatous disease, 9.7%; liver diseases and hepatiti
123 diates (ROIs) is the major defect in chronic granulomatous disease, causing recurrent infections and
124 ncies in the oxidative burst seen in chronic granulomatous disease, could lead to pathologic inflamma
125 such as Wiskott-Aldrich syndrome and chronic granulomatous disease, offering curative engraftment wit
128 gene therapy for immunodeficiencies, chronic granulomatous disease, suicide gene therapy for graft-ve
129 ranswells and cells of patients with chronic granulomatous disease, we show that this downregulation
130 OS) because cells from patients with chronic granulomatous disease, which are defective in ROS produc
131 as also observed in individuals with chronic granulomatous disease, who lack NADPH oxidase activity b
132 ts with the NADPH oxidase deficiency chronic granulomatous disease, who require antibiotic and antimy
148 hic macrophages constitutes the basis of all granulomatous diseases, such as tuberculosis or sarcoido
155 Similar abnormalities may extend to other granulomatous disorders, but not diseases such as ulcera
158 erculosis (MAP), occurs worldwide as chronic granulomatous enteritis of domestic and wild ruminants.
159 murafenib treatment, the patient developed a granulomatous eruption, which resolved 3 weeks after ces
160 o patients with melanoma developed cutaneous granulomatous eruptions during targeted BRAF inhibitor t
166 se includes indolent chronic rhinosinusitis, granulomatous fungal sinusitis, and acute fulminant fung
167 Herein, a case of severe vemurafenib-induced granulomatous hepatitis leading to chronic cholestasis i
168 e characterized by immune dysregulation with granulomatous hyperinflammation and autoimmunity, with r
177 small vessel disease and other inflammatory, granulomatous, infective, metabolic, and genetic causes
179 the predominant finding (42.2%), followed by granulomatous inflammation (29%), steatosis/steatohepati
180 i develop severe CD4 T cell-mediated hepatic granulomatous inflammation against parasite eggs associa
181 nonhematopoietic cells may partly facilitate granulomatous inflammation and bacterial dissemination.
182 a from the tissues, leading to local chronic granulomatous inflammation and compensatory adaptive imm
183 humans is attributed to parasite egg-induced granulomatous inflammation and fibrosis in the host live
184 thermore, a significant reduction of hepatic granulomatous inflammation and IL-17 production in inter
185 Crohn disease (CD) are both characterized by granulomatous inflammation and related to nucleotide oli
186 yllium (Be) exposure and is characterized by granulomatous inflammation and the accumulation of Be-re
187 occupational lung disorder characterized by granulomatous inflammation and the accumulation of beryl
188 crotizing vasculitis that is associated with granulomatous inflammation and the presence of anti-neut
189 at while a reduction in IL-4/IL-13-dependent granulomatous inflammation and tissue eosinophilia was o
190 nsure that any further complications such as granulomatous inflammation are managed and documented.
191 CBA/J (CBA) mice develop severe hepatic granulomatous inflammation associated with prominent Th1
192 Exserohilum provokes robust neutrophilic and granulomatous inflammation capable of thwarting fungal g
193 understanding of the pathways underlying the granulomatous inflammation characteristic of sarcoidosis
194 ysis of all 3 cases revealed elastolysis and granulomatous inflammation characterized by multinucleat
197 racterized by pronounced hepatic egg-induced granulomatous inflammation in a proinflammatory cytokine
200 ritical for the development of Th17-mediated granulomatous inflammation in the lung in response to S.
201 dritic cell-mediated development of a type 1 granulomatous inflammation in the lung in response to SC
202 responses are required for the generation of granulomatous inflammation induced by inhaled S. chartar
205 such as periprosthetic osteolysis, in which granulomatous inflammation is initiated by particle phag
208 pportunistic pathogenic bacterium, developed granulomatous inflammation of the ileum, characterized b
209 se resulting from lymphocytic and frequently granulomatous inflammation of the peripheral airways, al
210 is (GPA; or Wegener's granulomatosis) is the granulomatous inflammation of the upper respiratory trac
211 is syndrome had chronic active colitis, with granulomatous inflammation present in 7 of 11 patients (
214 in 2 patients and demonstrated noncaseating granulomatous inflammation surrounding tattoo ink in the
215 ith schistosome helminths is associated with granulomatous inflammation that forms around parasite eg
216 nge with 10(6) S. chartarum spores developed granulomatous inflammation with multinucleate giant cell
217 and challenged with 10(6) SC spores develop granulomatous inflammation with multinucleate giant cell
219 exclude infectious and autoimmune causes of granulomatous inflammation, followed by dermatologic wor
220 Since both responses usually correlate with granulomatous inflammation, we tested six prominently ex
227 of HPS and CD, 2 entities characterized by a granulomatous inflammatory reaction pattern but with uni
230 two models, with CFA causing a nonresolving granulomatous inflammatory response whereas tissue incis
231 amination revealed the presence of bilateral granulomatous keratic precipitates, anterior chamber cel
233 ve to conditions likely to be present within granulomatous lesions and mediate aspects of M. tubercul
234 lammatory myeloid neoplasia characterized by granulomatous lesions containing pathological CD207(+) d
235 there are no good models that replicate the granulomatous lesions found in granulomatosis with polya
236 f Crohn disease (CD); however, mucocutaneous granulomatous lesions have not been considered among the
238 his study, we show that Wnt6 is expressed in granulomatous lesions in the lung of Mycobacterium tuber
239 hich were observed in close proximity within granulomatous lesions in the lungs of GPA patients.
240 D4(+) T cells and macrophages form organized granulomatous lesions in the walls of affected arteries,
241 induced in the lungs and particularly in the granulomatous lesions of macaques experimentally infecte
242 ammoma body calcifications indicative of the granulomatous lesions that occur during Leishmania infec
250 n exposure, these mice developed more robust granulomatous lung fibrosis than wild-type counterparts.
251 -4Ralpha were associated with development of granulomatous lung inflammation triggered by silica.
254 necrotizing vasculitis, glomerulonephritis, granulomatous lymphadenitis, and bronchointerstitial pne
255 , HP is characterized by a bronchiolocentric granulomatous lymphocytic alveolitis, which evolves to f
256 d manifestations (notably the development of granulomatous-lymphocytic interstitial lung disease in C
257 sy of 2 eyes of 1 patient revealed prominent granulomatous lymphohistiocytic choroiditis with giant c
258 anent vision loss, 30 (94%) had a subretinal granulomatous mass/scar, peripheral granuloma with tract
261 emarkably, one celiac patient presented with granulomatous nodulae in the ileum, thus reflecting an i
262 t, metastatic disease, where ulcerations and granulomatous nodules can affect multiple secondary site
264 ing complaint for systemic disorders such as granulomatous or eosinophilic polyangiitis, and sarcoido
266 antly diminished clinical manifestations and granulomatous pathology and characterized by the presenc
267 that a subset of severe "asthma" manifests a granulomatous pathology, which we term "asthmatic granul
270 her, variable manifestations included atopy, granulomatous rash, autoimmune thyroiditis, the presence
271 ines from these CAR T cells in vivo drives a granulomatous reaction resulting in chronic toxicity.
272 ells in the mediastinal lymph nodes and lung granulomatous regions while concomitantly accelerating t
273 57BL6/J lacking SK1), to investigate how the granulomatous response and SK1-S1P pathway are interrela
274 y showed that B cells can modulate the local granulomatous response in M. tuberculosis-infected macaq
275 perienced a maturation defect of the ex vivo granulomatous response involving monocytes as well as na
276 apped eggs induce a distinct immune-mediated granulomatous response that causes local and systemic pa
277 ant cells is a distinguishing feature of the granulomatous response to inflammation, infection, and f
280 en- (Ag-) Ag-coated beads to elicit a recall granulomatous response, CCR4(-/-) mice displayed abrogat
281 ormation was not affected during a secondary granulomatous response, even though IL-5 and IL-13 were
285 the phenotypes of recruited T cells, and the granulomatous responses were also similar between WT and
286 y pulmonary infections, chronic invasive and granulomatous rhinosinusitis, and aspergillus bronchitis
288 -FDG PET/CT for detection of inflammation in granulomatous sites and management of patients with chro
291 are found within the mycobacterially induced granulomatous structure in the livers of infected Rag2(-
293 eficient macrophages formed mTORC1-dependent granulomatous structures in vitro and showed constitutiv
296 These data demonstrate that surveillance of granulomatous tissue by CD11c+ cells is continuous and t
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