ライフサイエンスコーパス: great promise

1 l inhibitor of Bruton tyrosine kinase, shows great promise.

2 erapeutics in neurodegenerative diseases has great promise.

3 ave been well-characterized, and others hold great promise.

4 merging immune-based therapies are providing great promise.

5 ibitor of P. aeruginosa quorum sensing shows great promise and validates our mechanistic approach to

6 ABSTRACT: Hmox1 protein holds great promise as a biomarker of in vivo stress responses

7 Succinylated Acha starches hold great promise as a good and cheaper replacement for gums

8 ayered molybdenum disulfide has demonstrated great promise as a low-cost alternative to platinum-base

9 ide perovskite solar cells (PSCs) have shown great promise as a low-cost, high-efficiency photovoltai

10 c deactivation of nerve agents, and it shows great promise as a new generic platform for a wide range

11 This aptasensor holds great promise as a new point-of-care diagnostic tool for

12 ping genetically engineered probiotics holds great promise as a new therapeutic paradigm to promote h

13 rminal domain protein inhibitors (BETi) hold great promise as a novel class of cancer therapeutics.

14 Fully integrated PET/MR imaging holds great promise as a novel hybrid imaging modality in onco

15 Gene transfer technology offers great promise as a potential therapeutic approach to the

16 erformance atomic Fe PGM-free catalyst holds great promise as a replacement for Pt in future PEMFCs.

17 by mobilizing endogenous progenitors, holds great promise as a therapeutic strategy for the diseases

18 AV)-mediated gene transfer to the liver held great promise as a therapeutic tool.

19 Despite their great promise as a tool for epidemiologists, social medi

20 olution-phase nanoscale materials, and holds great promise as a tool for monitoring dynamic self-asse

21 results suggest that oral vaccination holds great promise as a tool for the conservation of apes and

22 ation therapy with gemcitabine, it possesses great promise as a treatment of choice for PDAC/pancreat

23 Since its discovery, graphene has held great promise as a two-dimensional (2D) metal with massl

24 Ecoinformatics methods hold great promise as a vehicle for capitalizing on the explo

25 new lead-free inorganic perovskite may offer great promise as an alternative, highly efficient solar

26 Lithium metal has shown great promise as an anode material for high-energy stora

27 l and well-characterized self-molecule holds great promise as an ideal adjuvant for cutaneous vaccina

28 us, the PPARgamma ligands tested here showed great promise as antifibrotics, both in vitro and in viv

29 teria are photosynthetic prokaryotes showing great promise as biocatalysts for the direct conversion

30 es of tumors and tumor-associated cells hold great promise as biomarkers of clinical outcomes.

31 arbon-based radical chemistry, though it has great promise as building blocks for molecular electroni

32 anically coupled plasmonic devices thus hold great promise as building blocks for next-generation rec

33 These materials have shown great promise as catalysts for methane oxidation and sim

34 Transition metal oxides show great promise as Earth-abundant catalysts for the oxygen

35 ergy efficiency of Li-ion batteries, showing great promise as efficient electrical energy storage sys

36 x[4]arene-based container precursors exhibit great promise as enzyme mimics that function in organic

37 ility over thousands bending cycles, showing great promise as flexible electrodes for wearable optoel

38 quasi-two-dimensional nanoplates (NPLs) hold great promise as functional materials due to their combi

39 Ferroelectric domain walls hold great promise as functional two-dimensional materials be

40 The results show that these structures hold great promise as high load bearing and impact-resistant

41 nificant room for improvement and thus offer great promise as high-performance EUV resists for patter

42 thin organic semiconductors on graphene show great promise as highly efficient phototransistors.

43 able whirlpool-like spin textures that offer great promise as information carriers for future spintro

44 Bispecific antibodies show great promise as intrinsic combination therapies, but of

45 i-Conjugated organic oligomers/polymers hold great promise as long-range charge-transfer materials fo

46 n particular, nonhuman primates (NHPs) offer great promise as models for many aspects of human health

47 Live attenuated bacteria hold great promise as multivalent mucosal vaccines against a

48 range of cancers in clinical trials and show great promise as new additions to the cancer armamentari

49 Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents.

50 sieving of gas and solvated molecules shows great promise as novel separation platforms; however, sc

51 Plasmonic nanoparticles hold great promise as photon handling elements and as channel

52 Extracellular vesicles (EVs) hold great promise as potential therapeutic carriers.

53 ogether, the co-delivery system demonstrated great promise as potential treatment for MDR-related tum

54 In all, PR scaffolds hold great promise as potential treatments for visceral disea

55 Microscale soft-robots hold great promise as safe handlers of delicate micro-objects

56 teries (LiBs) and supercapacitors have shown great promise as sustainable energy storage systems [1-4

57 tide synthase (PKS) enzymes continue to hold great promise as synthetic biology platforms for the pro

58 ses has started to produce nanocrystals with great promise as the next-generation catalysts for a var

59 Immune checkpoint inhibitors show great promise as therapy for advanced melanoma, heighten

60 of nanomaterials within hydrogels has shown great promise, as a simple one-step approach, to generat

61 eterostructures of insulating materials hold great promise, as confirmed by perovskite oxide superlat

62 NAs for protein replacement therapies offers great promise but remains challenging.

63 of cross-species protein interactions holds great promise but requires sequencing many more species

64 Genomic testing carries great promise, but several ethical issues must be consid

65 ferroelectric (AFE) compounds, however, show great promise due to their atypical polarization-versus-

66 These optical nanomaterials also hold great promise for a broad range of applications spanning

67 These results suggest great promise for a broadly protective vaccine and also

68 (DASAs) are negative photochromes that hold great promise for a variety of applications.

69 Neuromorphic architectures offer great promise for achieving computation capacities beyon

70 cancer immunotherapy and future agents show great promise for achieving potent immune activation whi

71 Liquid biopsies hold great promise for achieving precision medicine.

72 ramatic results from AD animal models showed great promise for active and passive immune therapies ta

73 synthesize artificial genetic polymers hold great promise for advancing future applications in synth

74 n imaging and single-cell genomics that hold great promise for advancing our understanding of this in

75 costly, generating genome-edited pigs holds great promise for agricultural, biomedical, and pharmace

76 ts that this type of regulatory system holds great promise for applications in human gene therapy.

77 The results also hold great promise for applications in magnetic Dirac devices

78 CL) is a sensitive analytical technique with great promise for biological applications, especially wh

79 as components of drugs or cosmetics and hold great promise for biomedicine, yet their effects on cell

80 SCs) into hepatocyte-like cells (HLCs) holds great promise for both regenerative medicine and liver d

81 Tissue engineered conduits have great promise for bridging peripheral nerve defects by p

82 chnology is less than a decade old but holds great promise for bridging the gaps between patients, ge

83 ognition at individual level, but is also of great promise for broad physical sensing applications th

84 Overall, this therapeutic strategy holds great promise for calmodulinopathy patients as it repres

85 hese results suggest that the CDPGM NPs hold great promise for cancer theranostics.

86 conjugates (ADCs) of defined structure hold great promise for cancer therapies, but further advances

87 s indicate that several target pairings hold great promise for CAR therapy of AML.

88 Embryonic stem cells (ESCs) hold great promise for cardiac regeneration but are susceptib

89 beta-Cells derived from stem cells hold great promise for cell replacement therapy for diabetes.

90 onal insulin-producing beta-like cells holds great promise for cell replacement therapy for patients

91 T-cell genome engineering holds great promise for cell-based therapies for cancer, HIV,

92 rials to replace precious Pt catalysts holds great promise for clean energy technologies.

93 r to hydrogen through electrocatalysis holds great promise for clean energy, but its large-scale appl

94 Electronic health records hold great promise for clinical and epidemiologic research.

95 DNA detection with high sensitivity, showing great promise for clinical application and biomedical di

96 nsor exhibited high sensitivity and it holds great promise for clinical application and provides a ne

97 invasive and offers superb sensitivity, with great promise for clinical translation and quantitative

98 The presented methodology holds great promise for combinatorial screening of stem-cell a

99 Quantum information processing holds great promise for communicating and computing data effic

100 This holds great promise for compact accelerator building blocks an

101 templated UV-curing of the solvent, offering great promise for complex manufacturing, printing, seala

102 ructures with periodic phase separation hold great promise for creating two- and three-dimensional su

103 have such dual activity, our strategy holds great promise for cure research.

104 ch direct monitoring of the DNA damage holds great promise for designing new biosensors with modifica

105 ardiography, have emerged as techniques with great promise for determination of coronary microvascula

106 ectual disability in genetic disorders holds great promise for developing targeted treatments.

107 ctive loss-of-function (LoF) mutations holds great promise for devising novel therapeutic interventio

108 CRISPR-Cas9 genome editing technology holds great promise for discovering therapeutic targets in can

109 Human iPS cells hold great promise for disease modeling and treatment of dege

110 It holds great promise for drug development, and its optimization

111 Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G

112 dimensional semiconductors such as MoS2 hold great promise for electrical, optical and mechanical dev

113 atomically precise graphene nanoribbons hold great promise for electronic and optoelectronic applicat

114 nomaterials, such as graphene and MoS2, hold great promise for electronics and optoelectronics due to

115 Single cell RNA-Seq analysis holds great promise for elucidating the networks and pathways

116 On-chip photonic networks hold great promise for enabling next-generation high speed co

117 able energy production technology, it offers great promise for energy-sustainable developments and mi

118 midate morpholino oligomers (PMOs) has shown great promise for exon-skipping therapy of Duchenne Musc

119 show that Systems Biology-based methods have great promise for functional annotation of non-coding RN

120 ork demonstrates that these surfactants hold great promise for further application in the field of sy

121 ecific CTLs, and these ceramide analogs hold great promise for further development as adjunct agents

122 in the early phase of development, there is great promise for further development in structural magn

123 trol, demonstrating that this acceptor shows great promise for further optimization.

124 intracellular drug-release systems, holding great promise for future cancer therapy.

125 o achieve solar-to-chemical conversion is of great promise for future energy demands, but often limit

126 ia is emerging as a unique material, holding great promise for future market breakthroughs.

127 lded insights into sleep regulation and hold great promise for future research into sleep regulation

128 is viral vector and this delivery route hold great promise for gene therapy applications in both coch

129 ubject is less explored but may hold equally great promise for helping address fundamental questions

130 ransporter structural dynamics, and it holds great promise for high-throughput screening of chemical

131 time-resolved studies, the next decade holds great promise for hypothesis-driven research into the me

132 ained from camelid antibody libraries hold a great promise for immunoassay development.

133 e shortcomings, and how new initiatives hold great promise for improving gender equality in academia

134 utralizing antibody (bnAb) development holds great promise for improving the design of prophylactic i

135 These new 3D RVC-Au electrodes showed great promise for improving the power generation of EFC

136 th these limits at hand, nanomaterials offer great promise for improving transistor performance and a

137 sed on the adeno-associated virus (AAV) hold great promise for in vivo gene transfer; several unknown

138 o prepare a new generation of LFB, and shows great promise for in-field and point-of-care diagnosis o

139 onstrates how manipulating a few genes holds great promise for increasing recombination frequency in

140 Plasmonic photoconductive antennas have great promise for increasing responsivity and detection

141 This methodology holds great promise for investigating biologically significant

142 the development of liquid marbles, and shows great promise for liquid marbles based on UCNPs to be us

143 Silicon photonics holds great promise for low-cost large-scale photonic integrat

144 on of an electric field or vice versa, holds great promise for magnetic sensing and switching applica

145 Peptides containing silyl amino acids hold great promise for maintaining or reinforcing the biologi

146 major objective of nanotechnology and holds great promise for many applications.

147 ecognize biological macromolecules, and hold great promise for medical and clinical applications.

148 ost no immunogenicity in mice, demonstrating great promise for medical applications.

149 They hold great promise for metabolic engineering, but the behavio

150 Intestinal organoids offer great promise for modeling intestinal diseases; however,

151 d using the mono-exponential model has shown great promise for monitoring treatment response in prost

152 m, SN-38-encapsulated photonic micelles show great promise for multimodal cancer therapy.

153 noscale topological spin structures offering great promise for next-generation information storage te

154 induced pluripotent stem cells (hiPSCs) show great promise for obesity treatment as they represent an

155 l nonequilibrium macromolecular systems hold great promise for on-demand transformations, which resul

156 Self-assembled DNA nanostructures hold great promise for organizing biomolecules at the nanosca

157 therapeutic efficacy and safety demonstrate great promise for our strategy in future translational s

158 These data suggest great promise for pharmacological agents that prevent th

159 Moreover, BIA methods show great promise for portable analysis because battery-powe

160 smission electron microscopy (TEM) and holds great promise for potential applications in optoelectron

161 CoFe/BiFeO3 thin-film heterostructures show great promise for power-efficient electric field-induced

162 Thus, DD-SRM holds great promise for precisely measuring extremely low abun

163 Molecular imaging holds great promise for precision oncology, complementing tiss

164 est in vitro-in vivo extrapolation and holds great promise for predicting toxicokinetics of per- and

165 nversion of somatic cells into neurons holds great promise for regenerative medicine.

166 Direct cardiac reprogramming holds great promise for regenerative medicine.

167 thout going through a pluripotent state, has great promise for regenerative medicine.

168 rom < 0.1-10(4)ng/mL in blood), thus showing great promise for routine PSA diagnostics and for other

169 ctrolyte and abundant sodium resources, show great promise for safe, low-cost, and large-scale energy

170 DNA-coated colloids hold great promise for self-assembly of programmed heterogene

171 Noninvasive functional imaging holds great promise for serving as a translational bridge betw

172 Organic semiconductors hold great promise for SHC in an economical and environmental

173 ng under a dark-field microscope (DFM) holds great promise for single-particle analysis in bioimaging

174 -structured solid-state electrolyte exhibits great promise for SSLiBs owing to its high Li-ion conduc

175 thanide (Ln(3+)) doping in alumina has shown great promise for stabilizing and promoting desirable ph

176 Our rapid-scanning FT-CARS technique holds great promise for studying chemical dynamics and wide-fi

177 arbon-based porous thin film materials holds great promise for sustainable, energy-efficient desalina

178 Small-molecule inhibitors offer great promise for targeting pathways that are specifical

179 Eukaryotic microalgae hold great promise for the bioproduction of fuels and higher

180 lle-targeting of activity-based probes holds great promise for the characterization of enzyme activit

181 neration of high-quality graphene that holds great promise for the construction of hybrid materials.

182 analysis of large microbiome data sets holds great promise for the delineation of the biological and

183 Pharmacogenomics holds great promise for the development of biomarkers of drug

184 We believe that these promising results bear great promise for the development of microbubble-enhance

185 The field of microfluidics holds great promise for the development of simple and portable

186 f porous material (zeolites and MOFs) reveal great promise for the fabrication of sensors for exhaust

187 Engineered nanomaterials hold great promise for the future development of innovative p

188 lesterol acyltransferase-based therapy, hold great promise for the future.

189 Chimeric antigen receptors (CARs) have shown great promise for the immunological treatment of cancer.

190 s have now shown that this technology offers great promise for the improved diagnosis of the diseased

191 a of microbe discovery, now under way, holds great promise for the improvement of global health via t

192 Large-scale genome sequencing holds great promise for the interpretation of protein structur

193 al interfaces have been demonstrated to show great promise for the molecular charge storage and infor

194 ion, this PCQ-PCR-LFNAB cascade method shows great promise for the point-of-care diagnosis of cancer

195 ectrochemical exfoliation of graphite offers great promise for the preparation of graphene that can b

196 d magnetic resonance imaging (MRI) has shown great promise for the quantitative assessment of hepatic

197 Cu(2+) DEER with the dHis motif shows great promise for the resolution of precise, unambiguous

198 er, but chronnectome approaches already show great promise for the study of both the healthy and the

199 ficiency and safety of PAEs highlighting the great promise for the successful application of non-vira

200 f the shell of nano- and microcapsules holds great promise for the tailor-made design of new function

201 Regenerative medicine holds great promise for the treatment of degenerative retinal

202 Therapeutic nucleic acids hold great promise for the treatment of disease but require v

203 These cells show great promise for the treatment of neurological disorder

204 lls (Tregs) for clinical applications offers great promise for the treatment of undesirable immune re

205 Photoacoustic imaging holds great promise for the visualization of physiology and pa

206 Antibody-based immunotherapies hold great promise for treating a variety of diseases in huma

207 eutic proteins of wide-ranging function hold great promise for treating disease, but immune surveilla

208 ng adeno-associated viral (AAV) vectors hold great promise for treating Duchenne muscular dystrophy (

209 s of specific receptor populations, but hold great promise for treating numerous CNS disorders.

210 smart glucose-responsive Ex4 delivery holds great promise for type 2 diabetes therapy by providing s

211 anisms first be grown in pure culture, holds great promise for understanding key carbon transformatio

212 Thus, transcriptomic analysis offers great promise for understanding the integrative complexi

213 Monolayer WS2 offers great promise for use in optical devices due to its dire

214 ortable, low-cost, and scalable IM-PCR holds great promise for widespread biological, clinical, and e

215 nthanide(III)-based molecular scaffolds hold great promises for materials science and for biological

216 es for developing fluorescent platforms with great promises for use in imaging and sensor design.

217 py that target immune checkpoints have shown great promise in a variety of cancers, including metasta

218 reinforced with molecular strategies offers great promise in achieving more durable resistance and e

219 es, such as PG9, and its derivative RSH hold great promise in AIDS therapy and prevention.

220 of ultrabright fluorescent probes which hold great promise in biological imaging and analytical detec

221 Genetic engineering in pigs holds a great promise in biomedical research.

222 coherence Doppler tomography (ODT) has shown great promise in brain studies; however, high-speed micr

223 MicroRNAs (miRNAs) hold great promise in cancer research.

224 scovered small interfering RNA (siRNA) holds great promise in cancer therapy.

225 ically modified autologous T cells has shown great promise in cancer therapy.

226 Pluripotent stem cells (PSCs) hold great promise in cell-based therapy, but the genomic ins

227 PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models

228 miniscent of their parental cells, they show great promise in clinical diagnostics as EV analysis can

229 tration in cancer tissue samples which holds great promise in clinical screening of cancer biomarkers

230 choice for viral gene transfer and has shown great promise in clinical trials.

231 store or improve the clearance function hold great promise in delaying or preventing the onset of AD.

232 nd stability toward Lys detection may hold a great promise in developing other electrochemical sensor

233 ies of the terahertz waves in graphene holds great promise in enabling novel technologies for the con

234 Plasmonic nanostructures show great promise in enhancing the solar water splitting eff

235 High-throughput CRISPR screens have shown great promise in functional genomics.

236 rpretation, structural MRI continues to have great promise in furthering our understanding of how the

237 gh ion mobility spectrometry (IMS) has shown great promise in glycan isomer separation, conventional

238 inst human immunodeficiency virus (HIV) show great promise in HIV prevention as they are capable of p

239 tudies based on genes or pathways have shown great promise in interpreting association signals associ

240 tructures at near-atomic resolution and have great promise in molecular pharmacology, especially in t

241 Polygenic risk scores have shown great promise in predicting complex disease risk and wil

242 and sequencing projects, respectively, show great promise in providing a systems-level view of these

243 se is a rapidly growing field that has shown great promise in recent clinical trials.

244 This class of antibiotics holds great promise in recourse against infections by MRSA.

245 PMOs show great promise in reducing the cost of conversion of lign

246 f induced pluripotent stem (iPS) cells holds great promise in regenerative medicine.

247 ed diagnostic and therapeutic functions show great promise in terms of personalized nanomedicine for

248 of endogenous H2S in living cells, thus hold great promise in the analytical aspects of H2S.

249 D19 (chimeric antigen receptor [CAR19]) show great promise in the clinic to treat refractory CD19+ ac

250 oma viral oncogene)-Raf signaling have shown great promise in the clinic, but resistance remains a ma

251 c affinity for target biomacromolecules hold great promise in the development of novel tools for biol

252 inting and ultrasound techniques are showing great promise in the evolution of human musculoskeletal

253 Genetically encoded voltage indicators hold great promise in the study of neural circuitry, but real

254 Targeted antineoplastic agents show great promise in the treatment of cancer, having the abi

255 Antibody-based therapeutics exhibit great promise in the treatment of central nervous system

256 he BRAF-MEK-ERK signaling pathway have shown great promise in the treatment of malignant melanoma in

257 size dependent photoluminescence (PL) shows great promise in various optoelectronic and biomedical a

258 Such nanostructures have great promises in biomedical applications.

259 breakthrough in wavefront engineering shows great promises in controlling light propagation inside s

260 Therefore, this method offers great promises in providing a universal and efficient so

261 ctionality via a TE-EK approach, which holds great promises in translating the use of cultured CEnCs

262 hat the obtained hybrid nanoflowers may hold great promises in water remediation field and beyond.

263 This great promise is already justified in some early reports

264 Although TSPO imaging demonstrates great promise, its signal exhibits substantial interindi

265 Despite its great promise, neuroimaging has yet to substantially imp

266 Although these technologies show great promise, none are ready for widespread rollout for

267 While this technology holds great promise, obstacles to full implementation remain.

268 These studies show great promise of being applied within antibiotic drug di

269 ovel graphene-based materials but also shows great promise of designing new materials combined with u

270 Given the great promise of nanoRx with regard to engineering speci

271 In conclusion, this method shows great promise of opening new avenues in research on low-

272 es for devices utilizing ZCl demonstrate the great promise of symmetry-breaking charge transfer in or

273 Despite the great promise of the CRISPR-Cas9 technology, several cha

274 Despite the great promise of this technique for conservation biology

275 specificity and selectivity, indicating the great promise of this type of sensor for diagnostic appl

276 mplified electrochemical aptasensor offers a great promising protocol for ultrasensitive detection of

277 cells of the apical papilla (SCAP) represent great promise regarding treatment of neural tissue damag

278 Despite the great promise shown by these materials, their instabilit

279 While advances in neuroscience hold great promise, they also raise profound ethical, legal,

280 Genomic selection holds a great promise to accelerate plant breeding via early sel

281 ng wetlab and computational approaches holds great promise to accelerate TB biomarker discovery.

282 -vivo applications, and the technology holds great promise to advance the growing field of synthetic

283 f ectopic lymph node structures (ELNs) holds great promise to augment immunotherapy against multiple

284 Additionally, the fabricated thin film shows great promise to be integrated with the flexible electro

285 Collectively, PAI holds great promise to drive biomedical applications towards e

286 ome, transcriptome, and phenotype data holds great promise to extend the utility of genetic mapping,

287 vapour deposition technique (CVD) has shown great promise to generate high-quality TMD layers with a

288 re at an early stage of development but have great promise to improve MM treatment.

289 l drivers and growth rates in our model hold great promise to improve our understanding of ecosystem

290 n and treatment of critical illness, holding great promise to improve the acute and chronic outcomes

291 ially accumulate at sites of action and hold great promise to improve the therapeutic index of many d

292 nd accurate diagnosis of breast cancer holds great promise to improve treatability and curability.

293 with improved (micro)nutrient contents hold great promise to meet the increasing demand of nutrition

294 be established, but we believe that it holds great promise to provide targeted and highly effective t

295 ular vectors - known as BBB shuttles - offer great promise to safely overcome this formidable obstacl

296 hat LDLs reconstructed with fatty acids hold great promise to serve as effective and versatile nanoca

297 LncRNAs hold great promise to serve as important future therapeutic t

298 gnosis and individualized therapy, has shown great promise to transform medical care.

299 This device shows great promise toward use in enzyme-linked immunosorbent

300 Brain-inspired concepts have shown great promise towards addressing this need.