ライフサイエンスコーパス: greatly

1 rmal life and increasing the risk of suicide greatly.

2 f antibodies binding specific epitopes could greatly accelerate discovery of therapeutics as compared

3 ilization and acetic acid tolerance, and may greatly accelerate future genome-scale engineering endea

4 illary ligands have been identified that can greatly accelerate the C-H alkenylation of O-, S-, and N

5 find that those additional interactions can greatly accelerate the searching.

6 on of 4-OPA with AS and ammonium nitrate was greatly accelerated by evaporation of the solution sugge

7 ous release of fresh class-enzyme leads to a greatly accelerated enzymatic reaction processes without

8 Release of Tr-A from both formulations was greatly accelerated in vivo compared to in vitro using a

9 g declared a public health emergency and has greatly accelerated the pace of ZIKV research and discov

10 edicted to increase the mobility of this lid greatly accelerates LSD's binding kinetics and selective

11 The boronic acid moiety greatly accelerates the initial formation of a semicarba

12 catalytic arginine to the opposing subunit, greatly accelerating the rate of GTP hydrolysis.

13 l analysis and genome sequencing continue to greatly advance our understanding of this biochemical co

14 uding acute myeloid leukemia (AML), has been greatly advanced by genomics discovery studies that use

15 Quantifying this important metric has been greatly advanced by noninvasive techniques that allow em

16 e stress induction over the last decades has greatly advanced our understanding of stress responses i

17 ar magnetic resonance spectroscopy (NMR) has greatly advanced our understanding of the composition of

18 anscriptome analysis on diseased tissues has greatly advanced our understanding of the regulatory net

19 photonic devices and architectures, besides greatly advancing the fundamental understanding of tempo

20 atic conditions along geographical gradients greatly affect soil nutrient cycling processes.

21 etabolites involved in redox regulation were greatly affected 4 hours post-exposure in BAT, while no

22 Interaction of filoviruses with hosts is greatly affected by the viral interferon (IFN)-inhibitin

23 nd temperature, and the thermal conductivity greatly affected pore water signals.

24 In general, the oral conditions greatly affected the antioxidants, while gastric digesti

25 near-normal thresholds, whereas others were greatly affected.

26 ns used for existing representations without greatly affecting the rate of change of these representa

27 olarity influences the deactivation pathway, greatly affecting the strength of ion pairing between th

28 This loss greatly affects full recovery of motor function.

29 The human microbiota greatly affects physiology and disease; however, the con

30 Live imaging greatly aids these efforts, but the horizontal sample po

31 though the contexts in which they occur vary greatly, all are of concern.

32 Regulatory T cell counts and % varied greatly among cGvHD patients, and the increase post-ECP

33 le of UH vs. individual stochasticity varies greatly among demographic outcomes.

34 nitude and direction of these changes varied greatly among groups.

35 complexity of the protein-surface systems is greatly amplified by those of the polymer-fluid interfac

36 rmers able to recognize a chiral analyte and greatly amplify its chiroptical readout.

37 et of cells can, through population effects, greatly amplify oscillatory synchrony amongst unconnecte

38 The fitness value of leaves varies greatly and leaves are protected by jasmonate (JA)-induc

39 found that nucleosome occupancy in G1 varies greatly around origins across the S. cerevisiae genome,

40 he development of novel Ub-based reagents is greatly assisting in uncovering unknown aspects of Ub si

41 The loss of nsp15 activity also resulted in greatly attenuated disease in mice and stimulated a prot

42 ta indicate that a recent isolate of HFMG is greatly attenuated in the chicken host relative to the i

43 mor-opsonizing monoclonal antibodies, KWAR23 greatly augments myeloid cell-dependent killing of a col

44 This platform will greatly benefit both researchers and clinicians for inte

45 e most common bacterial infections and would greatly benefit from a rapid point-of-care diagnostic te

46 ct screening for new bioactive compounds can greatly benefit from low reagents consumption and high t

47 utic potential of these small molecules will greatly benefit the future of periodontal patient care.

48 Rationally designed AuNPs could greatly benefit their antimigration property, but the mo

49 While plant breeding efforts have greatly benefited from advances in genomics, profiling t

50 cade, knowledge of pathogen life history has greatly benefited from the advent and development of mol

51 erse generation of off-target mutations vary greatly between different organisms.

52 inetics and their activation by F-actin vary greatly between myosin-2 isoforms.

53 .The degree of strictness and agreement vary greatly between NP models applicable to marketing restri

54 tensively studied and has been found to vary greatly between species, but much less is known about th

55 eat-related deaths across the 33 GCMs varied greatly by RCP and adaptation and population change scen

56 ein-based bioconjugates has been facilitated greatly by recent developments in chemoselective methods

57 ew York City in coming centuries to increase greatly compared with preindustrial or modern flood heig

58 ed to almost zero, implying that IGEs indeed greatly contribute to the occurrence of evolutionary sta

59 Oral administration of vancomycin greatly dampened both CT immunogenicity and adjuvanticit

60 ble Ni, but accounting for Fe oxide-bound Ni greatly decreased variation in effect thresholds between

61 r LCLUC was excluded, EVI trend still varied greatly, decreasing in the windward but increasing in th

62 Human societies greatly depend on tools, which spare us considerable tim

63 ronic and optical properties of graphene are greatly dependent on the the number of layers.

64 strength of that influence, however, varies greatly depending upon the internal state of the body.

65 Overall, the in situ affinity ranking greatly depends on the on-rate instead of the off-rate.

66 V) are members of the Ebolavirus genus which greatly differ in their pathogenicity.

67 mprise individuals with the same genomes but greatly different behavioral repertoires.

68 Strikingly, chromatin shows greatly diminished higher-order structure after fertiliz

69 Moreover, the absence of Wnt7b led to greatly diminished levels of vascular endothelial (VE)-c

70 LCO nanoparticles, where the basal plane is greatly diminished to expose the edge sites, consistent

71 activation and folding of the WW domain are greatly diminished using evolutionary couplings-guided a

72 ohol misuse could substantially decrease the greatly elevated mortality risk among these patients.

73 eceptor expressed on myeloid cells 2) confer greatly elevated risk for developing the disease.

74 Such a priori knowledge would greatly empower serial monitoring strategies for drug re

75 ecially using accessible biospecimens, could greatly enable patient selection for targeted therapy.

76 ike histone chaperones interact with CSB and greatly enhance CSB-mediated chromatin remodeling.

77 and that transcriptomics has the capacity to greatly enhance ecological investigations of species dis

78 gional ozone precursors emissions and, thus, greatly enhance O3 attribution to source region.

79 ironmental epidemiology has the potential to greatly enhance our understanding of how environmental t

80 We show that CKS proteins greatly enhance the ability of Cdk2 to phosphorylate the

81 Also, the presence of "superemitters" greatly enhance the effectiveness of IR leak detection.

82 findings show how GSK3 kinase inhibition can greatly enhance the mature character of NK cells most de

83 d by applying a -0.45% compressive strain to greatly enhance the PD's response to 442 nm illumination

84 we developed a novel and simple strategy to greatly enhance the potency of the existing peptide-base

85 ed molecular domains prior to reaction could greatly enhance the regioselectivity of the dehydrocycli

86 g with a positive allosteric modulator would greatly enhance their function in physiological settings

87 heets with adjustable hole sizes that enable greatly enhanced alkali-ion storage properties.

88 Binding affinity is greatly enhanced by residues flanking the crystallograph

89 s with modest affinity and that affinity was greatly enhanced for mannose-linked alpha1-2 or alpha1-4

90 The resulting bicyclic peptide has greatly enhanced proteolytic stability as well as cell-p

91 Deoxycholic acid, a strong detergent, greatly enhanced the conjugation yield likely due to the

92 The addition of NZVI (0.5 g/L) greatly enhanced the decolourization rate of X-3B from 6

93 or and mitochondrial uptake of (177) Lu-PPNs greatly enhanced the efficacies of RT and/or PDT.

94 using a clinically available AhR antagonist greatly enhanced the in vitro generation of inducible Tr

95 The development of molecular genetics has greatly enhanced the study of the biology and pathology

96 ing to and infection of mucosal explants was greatly enhanced upon destruction of the respiratory epi

97 Here we show greatly enhanced valley spitting in monolayer WSe2, util

98 Moreover, glycogen synthase expression was greatly enhanced, consistent with elevations in muscle g

99 ed distant to the active site, the C2 domain greatly enhances catalytic turnover.

100 oglobulin-like fold generated a vaccine that greatly enhances leptospiral protection over vaccination

101 interfering RNA or selective inhibitor Ex527 greatly enhances MK-1775-induced growth inhibition and a

102 plication of X-ray free-electron lasers that greatly enhances our ability to determine protein struct

103 ich avoids use of a phase-transfer catalyst, greatly enhances synthetic effectiveness.

104 in the contact pathway and report that polyP greatly enhances the rate of all seven, while RNA is eff

105 oup 3 and Group 4 medulloblastoma subgroups, greatly enhancing previous knowledge.

106 e statistical fluctuations in the sample and greatly enhancing the final QDS rate in the finite-size

107 20 min to prepare 8 samples simultaneously, greatly enhancing the sample preparation throughput (<3

108 oxyporines, including enlarged mandibles and greatly enlarged apical labial palpomeres with dense spe

109 s ion manipulations (SLIM) that enables both greatly enlarged trapped ion charge capacities and also

110 n misophonic subjects, trigger sounds elicit greatly exaggerated blood-oxygen-level-dependent (BOLD)

111 an alter super-enhancer activity in a manner greatly exceeding repression of individual constituents.

112 unique to each ST ranges from 6.2% to 20.5%, greatly exceeding the differences observed within parasi

113 high soil Hg concentrations, with Hg masses greatly exceeding the levels found in temperate soils.

114 een reported and with sample throughput that greatly exceeds other existing proteomic methods.

115 , which also scales with nutrient uptake but greatly exceeds the requirement for growth.

116 In addition, these studies greatly expand the number of known thiostrepton analogue

117 en by specific non-covalent interactions can greatly expand the structural and functional space of su

118 the Hofmann House, where it centralized its greatly expanded literary activity including abstracts a

119 past several decades, numerous studies have greatly expanded our knowledge about how microtubule org

120 rious filoviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune r

121 Mass cytometry (CyTOF) has greatly expanded the capability of cytometry.

122 o samples from 10 countries and territories, greatly expanding the observed viral genetic diversity f

123 uces the overall energy requirements thereby greatly expanding the range of semiconductors that can b

124 This work greatly expands doping chemistry for tailoring the struc

125 Our study greatly expands the compendium of insulin promoter regul

126 This study greatly expands the number of genetic variants that may

127 the existing multichannel capabilities for a greatly extended number of volume channels, but also ena

128 The new proposed mechanism greatly extends the bandwidth of RCS reduction.

129 This greatly extends the flexibility in selecting the conjuga

130 functionality of this impedance sensor would greatly facilitate applications in portable medical devi

131 the development of this novel strategy could greatly facilitate our understanding of the role of BMP

132 s of gene networks from gene expression data greatly facilitate our understanding of underlying biolo

133 ored structures and a high growth rate would greatly facilitate research into the structure-property

134 ults to those obtained in male mice and will greatly facilitate studying female stress susceptibility

135 Identification of genes would greatly facilitate the elucidation of the biological mec

136 Bioorthogonally activated smart probes greatly facilitate the selective labeling of biomolecule

137 Our robot thus can greatly facilitate the study of in vivo full morphology

138 ing of multiple genes in a single vector has greatly facilitated both basic and translational studies

139 ing sensory processing and motor control are greatly facilitated by technologies that allow us to sim

140 Although superresolution microscopy has greatly facilitated high-resolution imaging of microtubu

141 This abundance of data has greatly facilitated maize research, but may not be amena

142 s in 3D electron microscopy (EM) imaging has greatly facilitated neuroscience research in high-throug

143 model organism Dictyostelium discoideum has greatly facilitated our understanding of the signal tran

144 anized connectivity of the visual system has greatly facilitated the discovery of novel mechanisms th

145 Quantitative analysis of 2D T1-T2 maps greatly facilitated the interpretation of T1 relaxation

146 rporated during reverse transcription, which greatly facilitates the protocol by eliminating two PAGE

147 Findings from central laboratories differed greatly for patients with lower levels of antibodies, bu

148 nized spatial patterns are likely to benefit greatly from conservation and restoration actions that u

149 Research on CTE would benefit greatly from incorporating principles established within

150 ion) can easily induce the sintering of NPs, greatly hampering their use in synthesis of novel cataly

151 le drug classes and now multidrug resistance greatly hampers patient management.

152 of this species are poorly understood, which greatly hampers practical research and conservation work

153 w drug delivery and therapeutic efficacy are greatly hindered by barriers presented by the vascular e

154 e small-animal model of dengue infection has greatly hindered the study of dengue pathogenesis and th

155 d evolutionary trajectory are unclear, which greatly hinders functional studies.

156 pation of light, photosensitizer, and oxygen greatly hinders the broad application of PDT as a first-

157 of a suitable third-order nonlinear material greatly hinders the development of this technology.

158 al ecosystem, and contains immune cells that greatly impact overall inflammatory homeostasis.

159 ein, dietary fibre, phenolics, and minerals, greatly impacted the flour properties.

160 n-2 gene, barr2, in beta-cells of adult mice greatly impairs insulin release and glucose tolerance in

161 antly reduces joint inflammation in vivo and greatly impairs the ability of neutrophils to form neutr

162 The knowledge of carbohydrate composition is greatly important to determine the properties of natural

163 iral delivery of CRISPR/Cas components would greatly improve future therapeutic utility.

164 geon ticks as a trigger of anaphylaxis would greatly improve medical care and advice for these patien

165 f contact regions between competitors should greatly improve our ability to understand and forecast c

166 These data also greatly improve the annotations of P. vivax gene untrans

167 Therefore, sulfidation can greatly improve the efficiency of utilization of reducin

168 ernels placed on similar orientation did not greatly improve the prediction ability.

169 mutant, here called "betaHP," that exhibits greatly improved amyloid nucleation without measurably e

170 ayer, the stability of the Ag-NW film can be greatly improved by 150-times compared with that of PVP-

171 s moving against less resistance, but can be greatly improved by positing a front-to-back gradient in

172 losses of microwaves in foams, leading to a greatly improved EMI shielding performance.

173 HSCT would be greatly improved if patient-specific hematopoietic stem

174 Despite greatly improved knowledge of the disease, therapeutic c

175 of a fully assembled biological system with greatly improved light penetration.

176 The greatly improved onset potential for electrocatalytic CO

177 Greatly improved performance in terms of discharged ener

178 the artemisinin derivatives while exhibiting greatly improved pharmacokinetics, low projected cost of

179 erotonin agonist (lorcaserin) to septic rats greatly improved repetitive firing and motor unit force

180 intestinal digestion (pepsin-trypsin system) greatly improved the antioxidant properties.

181 (IMiDs) and proteasome inhibitors (PIs) has greatly improved the overall survival of patients with M

182 We show that Secmarker greatly improves the accuracy of previously existing met

183 As such, this approach greatly improves the fluorescence image quality for exam

184 es of synthetic model compounds, but it also greatly improves the isolation of dO...N as a variable c

185 ng base-resolution methylation data, REPTILE greatly improves upon current methods for annotation of

186 therapeutics used to treat anemic patients, greatly improving their quality of life.

187 how that emission flow patterns have changed greatly in both domestic and foreign trade since the fin

188 nt with fast and slow components that differ greatly in time course.

189 stimulants like cocaine and methamphetamine greatly increase HS content and sulfation levels in the

190 ions of the terminal extensions of Drs2p can greatly increase its ATPase activity in the presence of

191 Our findings greatly increase knowledge about the geographic distribu

192 Visual inspection can greatly increase the confidence in calls, reduce the ris

193 MRI and serological and genetic testing have greatly increased accuracy in distinguishing multiple sc

194 ved closures that interrupt open bursts, was greatly increased at pHi 5.8 and 6.3.

195 unveiled that the copy numbers of NLRs were greatly increased by LTR-retrotransposon-mediated retrod

196 rther found that Matrigel substrate coatings greatly increased cell proliferation and uniquely affect

197 he health benefits of pomegranate juice have greatly increased consumer interest in this fruit.

198 s of the human plasma proteome that provides greatly increased depth of detection, improved quantitat

199 In addition, spawning duration was greatly increased for E. mordax, as the presence of larv

200 nd chevron-shaped features, whose density is greatly increased for higher contents.

201 While IRF3, STAT1/2, and IRF9 all greatly increased in concentration, there were no corres

202 er hypoxic conditions, HIF-1alpha levels are greatly increased in glioma stem-like cells.

203 ylation of ERK1/2 downstream of Ras are both greatly increased in Nf123aIN/23aIN mouse brain lysates,

204 ene associated with reduced bone density, is greatly increased in the cetacean liver under hypoxic co

205 Notably, gga-miR-429 was greatly increased in the CS group compared to levels in

206 tion of an IL-4-expressing adenoviral vector greatly increased in vivo ESC proliferation.

207 neutrophil uptake of P. aeruginosa and also greatly increased inhibition of T3S function, allowing f

208 Injection of TNF greatly increased levels of cell death in intestinal tis

209 ho wheeze during rhinovirus illnesses have a greatly increased likelihood of developing childhood ast

210 Next-generation sequencing technologies have greatly increased our ability to identify gene expressio

211 tions and multimorbidity are associated with greatly increased perceived stress among people in low-

212 new subtelomeric transcription in yeast, and greatly increased pervasive transcription in both yeast

213 People with epilepsy have greatly increased probability of premature mortality due

214 Here we show rapid evolution of greatly increased rates of dispersal by developmental ch

215 optimization of high-potency antibodies have greatly increased the chances for finding binding molecu

216 reater than the Tolerable Upper Intake Level greatly increased the odds of having high serum folate (

217 f Rev1 inhibited the activity of Polzeta and greatly increased the rate of all three 'X-dCTP' mispair

218 the interaction of warming and N deposition greatly increased the soil C input by 49%.

219 Removal of the core fucose of this glycan greatly increases the affinity for FcgammaRIII, resultin

220 is thaliana We then show that MMR deficiency greatly increases the frequency of both smaller-scale in

221 d library preparation strategy, our approach greatly increases the library complexity per unit of sta

222 tests, including pharmacological challenges, greatly increases the likelihood of diagnosis in familie

223 Electron beam illumination greatly increases the local concentration of free radica

224 Our study not only greatly increases the number of MPB loci, illuminating t

225 We show that Recycler greatly increases the number of true plasmids recovered

226 reduction in BAT vascular resistance, which greatly increases vascular perfusion of BAT.

227 ancestral threonine was mutated to alanine, greatly increasing resistance to DCV.

228 )] formation is quite rare, the prion can be greatly induced by overexpression of the prion domain of

229 ing factors linked to hemodynamic status can greatly influence the relationship between the severity

230 ilding onto existing protein scaffolds, have greatly influenced the course of enzyme evolution.

231 Genomic analysis has greatly influenced the diagnosis and clinical management

232 Both the technique and the coating material greatly influenced the encapsulation of antioxidant PC.

233 tion, AR gene expression knockdown via siRNA greatly inhibited cell growth and viability.

234 DN), or the specific Rac1 inhibitor NSC23766 greatly inhibits mutant p53 GOF in promoting tumor growt

235 ence on altered protein homeostasis has been greatly limited by intrinsic and acquired resistance.

236 turbations compared to conductive probes and greatly limits unwanted electrical pickup between probe

237 Although re-formation rates vary greatly, many megabase-sized loops recovered in under an

238 ry tests, suggesting that irrigation did not greatly modify wine quality under the conditions of this

239 The apparent mode-shift depended greatly on recording conditions.

240 ins and statin toxicity estimates but depend greatly on the disutility caused by daily medication use

241 organisms from specific domains of life, or greatly outdated.

242 e three- mitochondrial genome alignments and greatly outperformed the method currently used to visual

243 of the set-point compared to normal textile, greatly outperforming other radiative heating textiles b

244 Calculated sediment-water diffusive fluxes greatly overwhelmed the atmospheric depositional flux to

245 oposed mechanism that avoids such a shift is greatly preferred.

246 ration of the nanofibrils in rats results in greatly prolonged exposure, with a constant oxyntomoduli

247 ut next generation sequencing technology has greatly promoted the field of metagenomics where previou

248 out from MCF7 and A549 cells via Crispr/Cas9 greatly promotes cell viability, colony formation, and i

249 mitted by the Paschen law at these pressures greatly raise the separation speed, providing fair resol

250 uggests catalyzed diesel particulate filters greatly reduce emissions of SOA precursors along with pr

251 First, we greatly reduce off-target base editing by installing mut

252 the requirement for loss of both proteins to greatly reduce or ablate XRCC1 chromatin binding followi

253 th (EM-path) algorithm has been developed to greatly reduce the computational cost and facilitate mod

254 edes aegypti mosquitoes has the potential to greatly reduce the public health burden of the disease.

255 with versatile, preassembled reagents could greatly reduce the time and cost of in vitro or ex vivo

256 se intrinsic forms of phonon dissipation are greatly reduced (by >90%) by nonlinear saturation using

257 syringae Although SARD4 knockout plants show greatly reduced accumulation of Pip in leaves distal to

258 G175R is highly prone to aggregation and has greatly reduced activity.

259 Sample variance is greatly reduced after normalization, hence the power of

260 e species whose annual productivity was most greatly reduced by asynchrony.

261 The palmitic and stearic-based surfactants greatly reduced cocoa butter crystal size whereas the ol

262 Of note, the CTSD KO greatly reduced CTSB and trypsinogen activation in acina

263 -random structures in the Fourier space with greatly reduced design dimensionality.

264 epetitive spiking is restored, although at a greatly reduced firing frequency.

265 e-specific overexpression of beta-arrestin 2 greatly reduced hepatic GCGR signaling and protected mic

266 ir cells and hence cochlear amplification is greatly reduced in CD-1Cx30(A88V/A88V) mice.

267 Deleting MYC ESEs greatly reduced MYC expression and LCL growth.

268 e and probed over week-long experiments show greatly reduced rates of ageing.

269 '-tetrafluoro) were highly stable and showed greatly reduced susceptibility to CYP2D6-mediated metabo

270 Tyrosinase greatly reduced the solubility of oat protein despite li

271 However, these 5' deletions greatly reduced the synthesis of viral RNA in vitro, whi

272 Lake trout greatly reduced their use of littoral habitat and occupi

273 idization and washes at low temperatures, we greatly reduced this bias to enable nearly equivalent de

274 ns in the neighborhood of a tipping point to greatly reduced vaccine uptake and large epidemics.

275 aline on the capsaicin-activated current was greatly reduced, suggesting that activation of adrenergi

276 atic nuclei (SCN) by light was paradoxically greatly reduced, while the downstream activation of the

277 The LINORel combination greatly reduces bacterial adhesion and biofilm formation

278 ty acid (FFA) uptake by CD8(+) TRM cells and greatly reduces their long-term survival in vivo, while

279 ised law, could end illegal deforestation by greatly reducing the cost of monitoring, enforcement, an

280 eport that fibroblast-specific PTEN deletion greatly restricts mammary ductal elongation and induces

281 d transforming them into new solid fibers is greatly significant for applications.

282 Downstream interpretation is greatly simplified by preprocessing such a dataset as fo

283 ructural protein 1 and immunoglobulin M) has greatly simplified laboratory-based dengue diagnosis.

284 as other compressive sensing techniques with greatly simplified post processing, resulting in signifi

285 icrobial oligosaccharides are subjected to a greatly simplified purification scheme followed by struc

286 emerged as promising alternative to PCR and greatly simplify the implementation of amplification met

287 rug-repurposing/repositioning approaches can greatly speed up the traditional drug discovery process.

288 s recruitment to membrane-bound H-Ras, which greatly speeds the formation of a stable, membrane-bound

289 ue of redox ECs and has the added benefit of greatly stabilizing the reactive bromine generated durin

290 and IL-33 (1-100 ng/mL) in combination also greatly stimulate TNF secretion (by 4,500-fold).

291 protein unique to eukaryotes, binds CMG and greatly stimulates its helicase activity in vitro.

292 ecruits LRRK2 to the trans-Golgi network and greatly stimulates its kinase activity.

293 during hypoxia or anesthesia and contributes greatly to the hypertension caused by baroreceptor deaff

294 of motor cortex plasticity has been advanced greatly using rodents as experimental animals.

295 Data values also have greatly varying magnitudes.

296 to neoplasia; risk for progression increased greatly when all 3 pathologists agreed on LGD (odds rati

297 This greatly widens the range of applications for the cryogen

298 Since then, the field has progressed greatly, winning two Nobel Prizes and seeing the impleme

299 nditions classically used to elicit USV vary greatly with the animal's age (isolation from the dam in

300 Membrane lipid composition varies greatly within submembrane compartments, different organ