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1                            We then outline a groundwork computational model that can simulate cellula
2 ISPR/Cas9 technologies were built on as this groundwork demonstrated the need for solutions and the b
3 der these findings in the context of earlier groundwork exploring the contribution of chemokines to T
4                              The results lay groundwork for 3D layer-on-layer nanomaterial assemblies
5                  This understanding lays the groundwork for a better control of the growth of vdW het
6                           Our study lays the groundwork for a class of injectable therapeutic enzymes
7 stic effects of human impacts are laying the groundwork for a comparably great Anthropocene mass exti
8             The present findings provide the groundwork for a comprehensive bottom-up account of spee
9 uct, and that data-driven ontologies lay the groundwork for a cumulative psychological science.
10                              SQUICH lays the groundwork for a general solution to a fundamental probl
11 nication during mouse courtship, and lay the groundwork for a mechanistic dissection of communication
12 al motifs of this channel family and lay the groundwork for a mechanistic understanding of how Piezos
13 quired for precise segmentation and lays the groundwork for a mechanistic understanding of how the pa
14 of this article is, consequently, to lay the groundwork for a more coherent concept of empathy and th
15 tion of an embedding spindle matrix lays the groundwork for a more complete understanding of microtub
16 nt environmental conditions and thus lay the groundwork for a more complete understanding of the matr
17                       This analysis lays the groundwork for a more comprehensive understanding of the
18 n made both in diagnostic methods and in the groundwork for a neurobiological model, no clear rationa
19 ture diameter and rigidity, establishing the groundwork for a new generation of biomimetic material i
20                         Our findings lay the groundwork for a new generation of versatile, biomedical
21  malignant vascular tumors and have laid the groundwork for a promising treatment of angiosarcomas in
22 lems produced by the pandemic and to lay the groundwork for a scientific agenda to capture and unders
23 erved for RNA folding processes and lays the groundwork for a significantly improved understanding of
24 ewing acoustic sensor data and lays down the groundwork for a surface technique where quantitative in
25              Together, these results lay the groundwork for a theoretical framework to connect ecolog
26 fer community assembly processes but lay the groundwork for a theoretically justified trait-based com
27 ave laid the methodological and experimental groundwork for a vastly improved knowledge of the as yet
28 is electromagnetic forming approach lays the groundwork for a versatile, time- and energy-efficient m
29                        These results lay the groundwork for AAV-mediated gene therapy experiments in
30 in, and repair tissues and have provided the groundwork for additional exploration and discovery of p
31 and their progression, while also laying the groundwork for additional modeling and validation in adv
32                 These findings might lay the groundwork for an improved CRC risk stratification-based
33                        These studies lay the groundwork for an improved mechanistic understanding of
34                          This study lays the groundwork for an understanding of the mechanisms of the
35              Here we establish a theoretical groundwork for analyzing protein thermodynamics using si
36                       These insights lay the groundwork for animating crystal structures with biochem
37 s to a relatively simple system, it lays the groundwork for application to biologically important com
38 ibutes of monolayer graphene resonators, the groundwork for applications of these devices, including
39                         This system lays the groundwork for applications to an environmentally friend
40                              Here we lay the groundwork for appreciating the mechanisms and consequen
41                          Our results lay the groundwork for assessing longitudinal changes in working
42 h residual kinesthetic sense and provide the groundwork for augmenting cortically controlled BMIs wit
43 luation and medical optimization provide the groundwork for best medical practice in an otherwise hig
44                          This study lays the groundwork for better understanding the circuit-level un
45                 This study begins to lay the groundwork for calculating pediatric IOL power in catara
46  of this slit diaphragm protein and lays the groundwork for characterizing the interactions between k
47  regulation of Rab12 activation and lays the groundwork for characterizing the regulation of other DE
48 s in working memory in childhood and lay the groundwork for characterizing the ways in which they cha
49 therapeutic approaches for CMT1A and lay the groundwork for clinical trials in humans afflicted with
50 nocot angiosperms, and lays the phylogenetic groundwork for comparative analyses of the drivers and c
51 dules with tissue-specific activity lays the groundwork for complete characterization and deciphering
52                        These results lay the groundwork for continued translational development of th
53 ty of the real-time intervention, laying the groundwork for controlled trials with larger sample size
54 ighlighted, with the objective of laying the groundwork for creating a normal quality and duration of
55 oy formation revealed here may establish the groundwork for creating bimetallic and multimetallic nan
56                These findings laid important groundwork for current in-vivo studies on the role of fi
57 n rodents across the lifespan, providing the groundwork for deciphering disease mechanisms and develo
58 s important for hippocampal CaCC, laying the groundwork for deciphering the dynamic CaCC modulation o
59 understanding of the CCM, thereby laying the groundwork for deeper study and engineering of the cell
60                          This study lays the groundwork for detailed investigations of the mechanisms
61                          This study lays the groundwork for developing a better understanding of the
62                   The present study lays the groundwork for developing a systematic and automated met
63 g a simple, cost-effective means and lay the groundwork for developing additional highly sensitive bi
64                         It also provides the groundwork for developing additional studies to investig
65                       This research lays the groundwork for developing an alternative in situ remedia
66                   These observations lay the groundwork for developing cardiospheres as a novel off-t
67              This comparative study lays the groundwork for developing improved tools and formalized
68        Taken together, these results lay the groundwork for developing new diagnostics and individual
69               The discovery of CER9 lays new groundwork for developing novel cuticle-based strategies
70                          This study lays the groundwork for development of a diagnostic test that can
71  of organo-Bcat compound classes and lay the groundwork for development of additional practical boryl
72                             This establishes groundwork for development of molecular MR imaging-guide
73 cancer target, and our studies could lay the groundwork for development of novel cancer therapeutics.
74 from this study are important for laying the groundwork for discovery and design of high-affinity lig
75                       These findings lay the groundwork for editing the loop sequence and structure f
76 of energy transfer in materials and provides groundwork for efficient utilization in artificial photo
77                                   To set the groundwork for elucidating neural roles for Nrg3, we stu
78 of a common polymorphism of CFH and lays the groundwork for elucidating the role of CFH in AMD pathog
79                These innovations provide the groundwork for enabling enhanced and more natural fine m
80                      The results provide the groundwork for energy policies focused to maximize socio
81 al type II polyketide synthases and lays the groundwork for engineered biosynthesis of new bioactive
82                          Our studies lay the groundwork for epigenetic modification and mechanistic s
83                          The results lay the groundwork for establishing a novel animal model and a n
84                         Our findings lay the groundwork for establishing gene expression profiles tha
85 lish plaque stability, these studies lay the groundwork for exploration of mechanisms by which gap ju
86 e for activated astrocytes in AD and lay the groundwork for exploration of other novel astrocyte-base
87 ni-, bi- and multivariate scales and lay the groundwork for further clinical studies that might lead
88          The strategy proposed here lays the groundwork for further comparative analyses between huma
89               We believe this study lays the groundwork for further development of this series as a t
90                        This ability lays the groundwork for further enhancing the assay throughput by
91  Together, the results of this study lay the groundwork for further evaluation of mechanisms underlyi
92                           This paper set the groundwork for further evaluation of the input of other
93 prefrontal asymmetry in affect, and lays the groundwork for further exploration into the cortical mec
94         Collectively, these findings lay the groundwork for further exploration of MgSnN(2) as a mode
95        This thought-provoking study lays the groundwork for further exploration of this adapted antib
96 monary bacterial infections and provides the groundwork for further investigation into SPMs as altern
97                        Our analysis lays the groundwork for further molecular studies of lung adenoca
98                       These findings lay the groundwork for further preclinical translation of this a
99 These results bring new insights and lay the groundwork for further research on acylated anthocyanins
100 HFGP studies presented in this issue lay the groundwork for further studies aimed at understanding th
101 une subphenotype may exist in MS and lay the groundwork for further studies focusing on the pathogeni
102                         Our insights lay the groundwork for further studies of CNbeta1, whose physiol
103                           This work lays the groundwork for further use of this technology in nuclear
104 t model for giant phage research, laying the groundwork for future analyses of their highly unusual v
105 the auditory pathway in rodents and lays the groundwork for future applications of cochlear optogenet
106 time and accuracy) of this technique lay the groundwork for future applications of FC-ICP-MS for the
107                    These results provide the groundwork for future behavioral studies.
108 anism of SEDS-family polymerases and lay the groundwork for future biochemical and structural studies
109 ic plaques and stenosis using NETs may lay a groundwork for future clinical detection and improving C
110 l therapy of DNMTi and dasatinib, laying the groundwork for future clinical investigations.
111                    These experiments lay the groundwork for future construction of programmable auto-
112                          Our results provide groundwork for future development of clinical protocols
113 r function and hepatic steatosis, laying the groundwork for future diagnostic and therapeutic applica
114                           Our study lays the groundwork for future efforts to repurpose prazole-based
115                        These studies lay the groundwork for future enzyme engineering to broaden the
116 on to unpredictable environments and lay the groundwork for future evolution studies in rotifers.
117 ting social cognition and action, laying the groundwork for future experiments that can illuminate th
118                    These studies provide the groundwork for future improvements in device design.
119 hich BFT induces tumor formation and lay the groundwork for future in vivo studies to explore the imp
120                 This work provides important groundwork for future in-depth studies of VF dynamics an
121                Our results provide important groundwork for future investigations of predator-prey dy
122 ity of primary mouth formation, and lays the groundwork for future molecular analyses of this importa
123                          This study lays the groundwork for future molecular studies of Apis neuropep
124 lated cognitive impairment and contribute to groundwork for future non-pharmacological interventions
125                          This study lays the groundwork for future pHis proteomics studies in bacteri
126                          This study lays the groundwork for future research related to the environmen
127 insight into PNN structure and lay important groundwork for future strategies to specifically disrupt
128         The results of these studies lay the groundwork for future strategies to therapeutically expl
129                        These results lay the groundwork for future structural and functional dissecti
130 re anti-HBs seroconversion and represent the groundwork for future studies aimed at assessing whether
131 ession and metastasis, these results lay the groundwork for future studies assessing the therapeutic
132 ssing in psychiatric conditions, and lay the groundwork for future studies examining how reduced inte
133 ng with structural insight provides critical groundwork for future studies for the family of AMPylato
134  with detoxification genes and lay important groundwork for future studies in the field of evolutiona
135                       These findings lay the groundwork for future studies into the potential role of
136                          Our results lay the groundwork for future studies of AlkB and its human homo
137 t, long-range spin interactions and lays the groundwork for future studies of many-body dynamics in s
138                           This work lays the groundwork for future studies on adapting the blocker mo
139 egulator of epithelial mechanics and lay the groundwork for future studies on how anillin may contrib
140                           This work lays the groundwork for future studies on the functional roles of
141 er, the results of these two studies lay the groundwork for future studies to determine how, in the f
142  these mutant p53 knock-in mice has laid the groundwork for future studies to elucidate the in vivo p
143  Together, the results of this study lay the groundwork for future studies to explore the role of DNA
144 walking on a spherical treadmill, laying the groundwork for future studies to image the brain during
145 rease gene targeting efficiency and lays the groundwork for future studies using aptamers for gene ta
146 y applied to study PNS disorders and lay the groundwork for future therapeutic application of optogen
147 ica in response to infection and provide the groundwork for future virulence studies.
148                             Our data lay the groundwork for genetically informed conservation and adv
149 ing the mechanism of this inhibitor lays the groundwork for identifying cancer targets.See related ar
150                        These results lay the groundwork for identifying genes responsible for the ear
151                                This lays the groundwork for identifying individuals who may benefit f
152 ism at the TI-FMI interface but also lay the groundwork for imaging magnetic domains and domain bound
153                         This review sets the groundwork for implementing a value-based, patient-cente
154  to unlock this riddle, however, and lay the groundwork for improved cancer therapies.
155      Collectively, this information lays the groundwork for improved understanding of the endogenous
156                      Broadly, we provide the groundwork for incorporating pH effects into empirical a
157 udies of immune cell populations and lay the groundwork for informed cell engineering and precision m
158                       These findings lay the groundwork for intercalation- and termination-engineered
159 l constituents of the human gut will set the groundwork for interpreting how the gastrointestinal mic
160                          This study lays the groundwork for interventions aimed at modulating V. chol
161                                       To lay groundwork for investigating unequal divisions in the le
162 enerative signaling, and ultimately lays the groundwork for investigations on the therapeutic efficac
163 l characterization of EGF816 and provide the groundwork for its current evaluation in phase I/II clin
164                            Our work lays the groundwork for label-free drug screening in pharmaceutic
165                       This approach lays the groundwork for large-scale and cost-effective bacterial
166 ently, international consortia have laid the groundwork for large-scale genomics and microbiome studi
167                        These results lay the groundwork for mechanistic/deconstruction experiments to
168                    This study lays important groundwork for metabolic engineering efforts aimed at im
169 ed neural computing introduced here lays the groundwork for more advanced metabolic circuits for rapi
170        Finally, our methodology provides the groundwork for more chemically detailed investigations o
171                          This study lays the groundwork for more comprehensive models that can handle
172               Overall, these results lay the groundwork for more detailed studies of venom function a
173                 The results lay a conceptual groundwork for more effective studies of heterogeneity a
174                          Our results lay the groundwork for more in-depth explorations of the propert
175 t into RV2 rhadinovirus biology and sets the groundwork for more intensive next-generation (Next-Gen)
176                         Our findings lay the groundwork for new applications of colloids and liquid c
177 er chronic degenerative diseases, laying the groundwork for new therapeutic strategies.
178   The determination of VOC profiles lays the groundwork for non-invasive probes of bacterial metaboli
179 i flux in acute inflammation and provide the groundwork for novel anti-inflammatory strategies for tr
180 signaling during cardiac healing and provide groundwork for novel anti-inflammatory strategies in tre
181 al phase transition provide the experimental groundwork for opening the research on novel topological
182                          Our method lays the groundwork for other generalizations of graph-theoretic
183           These mainstays of therapy set the groundwork for other possible interventions such as medi
184 hird-generation EGFR inhibitors will lay the groundwork for overcoming the next generation of resista
185 s for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale n
186                          Our results lay the groundwork for potential investigations of the efficacy
187 -dependent plasticity, these results lay the groundwork for probing microanatomical rearrangements th
188 twork during persistent activity and lay the groundwork for quantitative comparisons to theoretical m
189 erlie important cell functions is laying the groundwork for quantitative identification of protein-in
190             In the present study, we lay the groundwork for quantitative single-molecule measurements
191 he selective inhibition of TRPV5 and lay the groundwork for rational design of new classes of TRPV5 m
192 ry proteins, these results lay the potential groundwork for repurposing cancer drugs for neuropsychop
193                    This provides mechanistic groundwork for repurposing clinically approved JAK1/JAK2
194                          This study lays the groundwork for resolving the origin of the SLE transcrip
195 hput rapidly increases, promising to lay the groundwork for revolutionizing our understanding of the
196  measure PSD activity in vitro have laid the groundwork for screening chemical libraries for PSD inhi
197                      In addition, we set the groundwork for similar reciprocal inhibition approaches
198 cludes interactions and decoherence lays the groundwork for simulations of the transverse-field Ising
199                        These studies lay the groundwork for strategies to target essential chaperone-
200                           This work lays the groundwork for structure determination of other lasso pe
201 ion and dephosphorylation by CN and lays the groundwork for structure-based development of new CN inh
202 ain recent experimental findings and lay the groundwork for studying the hierarchical molecular mecha
203                             Here, we lay the groundwork for such a theory, starting with a key observ
204                          This study lays the groundwork for synthetic signalling networks between pla
205 ement cell shapes, and lays the quantitative groundwork for testing hypotheses about pavement cell fo
206 ues that direct cleavage of CSF and laid the groundwork for testing whether other Phr peptides are pr
207  engineering, is highlighted, which lays the groundwork for the clinical trial approval of Nell-1.
208 f simple biological systems may also lay the groundwork for the construction of more complex systems
209                       This research lays the groundwork for the control of complex elastic deformatio
210 derstanding of this process while laying the groundwork for the creation of new chemical and biologic
211 ticles and block copolymers, and it lays the groundwork for the design of cooperatively assembled fun
212                        These results lay the groundwork for the design of effective Cry5B-based anthe
213                           This work lays the groundwork for the design of ligand-based NP formulation
214 lum stress in myelinating cells has laid the groundwork for the design of new therapeutic strategies
215 ross-inhibitor of PlasmodiumSUB1, laying the groundwork for the development of a globally active smal
216 ction, the results of this study may lay the groundwork for the development of effective clinical str
217 ls and highlight studies that are laying the groundwork for the development of effective therapeutic
218              Therefore, our findings provide groundwork for the development of highly specific and sa
219 investigating lncRNAs in cancer and lays the groundwork for the development of new diagnostics and tr
220 orate in protein remodeling will provide the groundwork for the development of new therapeutic strate
221 d understanding its pathophysiology will lay groundwork for the development of new treatments.
222 ification of Notch target genes, and lay the groundwork for the development of Notch pathway inhibito
223  Gal-deficient IgA1 hinge region and lay the groundwork for the development of reliable diagnostic to
224 f siphovirus-mediated HGT, but also lays the groundwork for the development of sensitive affinity-bas
225 lational modification cross talk may lay the groundwork for the development of specific therapeutic c
226 ueous conditions in high yield, and lays the groundwork for the development of sulfinic acid detectio
227 neurodegenerative diseases and establish the groundwork for the development of therapeutic strategies
228 ned from these studies contributed important groundwork for the eventual development of antiviral dru
229                          This study lays the groundwork for the eventual identification of common TS
230                    These results provide the groundwork for the experimental verification of the func
231                           These data lay the groundwork for the exploration of EC therapies that can
232  association, thereby establishing important groundwork for the functional characterization of FtsB i
233            The results of this study lay the groundwork for the further evaluation of CAR-expressing
234             This methodology constitutes the groundwork for the future development of a spray to dete
235  mutation with direct visualization laid the groundwork for the future development of detector-free t
236 lved in vivo habenula imaging, and provide a groundwork for the future development of magnetic suscep
237                             Our data provide groundwork for the implementation of molecular ultrasoun
238            This fundamental concept laid the groundwork for the notion of a modular sensory cortex, c
239                          This study lays the groundwork for the on-going development of image-guided
240 omal peptide synthetases (NRPSs) and lay the groundwork for the rational reengineering of NRPSs by sw
241 h miniaturized detection systems may lay the groundwork for the real-time, point-of-care detection of
242           Our study lays important technical groundwork for the realization of human kidney regenerat
243 al activity to control materials and lay the groundwork for the rise of materials science beyond equi
244                        These results lay the groundwork for the study of variation in sporulation eff
245                                  Much of the groundwork for the understanding of mast cells was estab
246 r proteins and monogenic autism, and lay the groundwork for the use of mGlu5 receptor antagonists in
247                                          The groundwork for these changes began a decade ago with the
248 ceptor complexes can be drugged, and lay the groundwork for this nascent area of research.
249                       Our goal is to lay the groundwork for this technique and establish it as a new
250 uding the foundational efforts that laid the groundwork for today's investigations, and detail the mo
251                                          The groundwork for tracing the evolution of regulatory eleme
252  3 types of human breast cancers and lay the groundwork for translation of these measures to the clin
253 s unique to hvKP, which is needed to lay the groundwork for translational approaches to prevent or tr
254 al in the pathophysiology of AUD and lay the groundwork for treatments targeting the epigenetic mecha
255 gn criteria derived from this study lays the groundwork for ultrabright fluorescence bullets for in v
256                        This finding lays the groundwork for understanding cell-based biological pacem
257  primates, as well as establishing essential groundwork for understanding future work linking genetic
258 he tracking of local confidence, and lay the groundwork for understanding how a formation of global s
259                          This study lays the groundwork for understanding Ric8A function at the molec
260                        These results lay the groundwork for understanding the differential sensitivit
261             Collectively, our study lays the groundwork for understanding the molecular basis of a ke
262  bacterial chaperone system will provide the groundwork for understanding the more complex eukaryotic
263        Simple perceptual tasks have laid the groundwork for understanding the neurobiology of decisio
264                          Our studies lay the groundwork for understanding the role of Pax7 in orchest
265 rmeation, selectivity and gating and lay the groundwork for understanding the role of TMEM175 in lyso
266                      In doing so, we lay the groundwork for understanding these elaborate protein com
267                  These studies have laid the groundwork for unraveling new enzymatic strategies for d
268                          Our results lay the groundwork for using a phylogenetic approach to correct
269                          This study lays the groundwork for using alkaline-earth atoms as testbeds fo
270 arcoma clinical characterization and lay the groundwork for using Boolean-based probabilities to iden
271                          Our results lay the groundwork for using fermionic optical lattice clocks to
272 nfected fish to healthy fish, which lays the groundwork for using LJ001 as a possible therapeutic for
273                           Our study lays the groundwork for using moire superlattices to simulate a w
274                        First, we lay out the groundwork in the 1950s aimed at the development of a ph
275                                    Moreover, groundwork in this area using engineered protein nanopor
276                                     Thus the groundwork is being laid for researchers to exploit exis
277                  This work lays the critical groundwork necessary to access even higher oxidized taxa
278 craniofacial complex in baboons provides the groundwork needed to establish the baboon as an animal m
279                      This study provides the groundwork needed to uncover the correlation among oxida
280                        These results lay the groundwork needed to understand the structure of the CA-
281           These results provide the valuable groundwork required to further understand how Nature cod
282              Our research contributes to the groundwork studies to determine the geographical origin
283  will result in a more thorough model of the groundwork the human brain was built upon.
284  population-wide treatment approach lays the groundwork to achieve HCV elimination in coinfected MSM.
285                                This lays the groundwork to design longer, and therefore stickier, off
286 tarvation and recovery, and lays the initial groundwork to develop Methyloprofundus as a model chemos
287 and validated that establishes the necessary groundwork to enable large population-based assessments
288 mortem and clinical studies that can lay the groundwork to evaluate the potential of locus coeruleus
289 lpha-syn lysosomal degradation, establishing groundwork to explore mechanisms to enhance their cellul
290 at this noncovalent interaction provides the groundwork to explore molecular mechanisms linking PD wi
291 mitochondrial apoptotic p53 program lays the groundwork to further investigate its efficacy and safet
292 e challenging, recent advances have laid the groundwork to initiate these biotechnological solutions
293                 Our data lay the fundamental groundwork to investigate microglia-astrocyte cross talk
294  directly in a biological matrix, laying the groundwork to perform in vivo measurements in a near fut
295 proaches like this will be useful to lay the groundwork to reconstruct regulatory networks on the lev
296 ematic approach to drug repurposing lays the groundwork to streamline future drug development efforts
297 f early functional adaptations could lay the groundwork to test therapeutic interventions that halt o
298 time studies in monkeys had begun to lay the groundwork to understand the functional organization of
299                          This study lays the groundwork to understand the transcription factors that
300                As such, they provide initial groundwork toward understanding how ER stress sensors ca

 
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