ライフサイエンスコーパス: groundwork

1 This groundwork allowed us to achieve higher resolution in th

2 ed approach and initial findings provide the groundwork and stimulus for establishing international h

3 We then outline a groundwork computational model that can simulate cellula

4 ISPR/Cas9 technologies were built on as this groundwork demonstrated the need for solutions and the b

5 der these findings in the context of earlier groundwork exploring the contribution of chemokines to T

6 The results lay groundwork for 3D layer-on-layer nanomaterial assemblies

7 stic effects of human impacts are laying the groundwork for a comparably great Anthropocene mass exti

8 The present findings provide the groundwork for a comprehensive bottom-up account of spee

9 c stem-cell transplantation has provided the groundwork for a cure of chronic myelogenous leukemia.

10 ity and aggresome formation and also lay the groundwork for a direct test of the role of aggresome fo

11 These results provide the groundwork for a genetic linkage analysis to identify th

12 nication during mouse courtship, and lay the groundwork for a mechanistic dissection of communication

13 al motifs of this channel family and lay the groundwork for a mechanistic understanding of how Piezos

14 tion of an embedding spindle matrix lays the groundwork for a more complete understanding of microtub

15 nt environmental conditions and thus lay the groundwork for a more complete understanding of the matr

16 This analysis lays the groundwork for a more comprehensive understanding of the

17 n made both in diagnostic methods and in the groundwork for a neurobiological model, no clear rationa

18 ture diameter and rigidity, establishing the groundwork for a new generation of biomimetic material i

19 Our findings lay the groundwork for a new generation of versatile, biomedical

20 malignant vascular tumors and have laid the groundwork for a promising treatment of angiosarcomas in

21 otocol is that it does not appear to lay the groundwork for a self-enforcing treaty).

22 erved for RNA folding processes and lays the groundwork for a significantly improved understanding of

23 ewing acoustic sensor data and lays down the groundwork for a surface technique where quantitative in

24 Together, these results lay the groundwork for a theoretical framework to connect ecolog

25 fer community assembly processes but lay the groundwork for a theoretically justified trait-based com

26 ave laid the methodological and experimental groundwork for a vastly improved knowledge of the as yet

27 is electromagnetic forming approach lays the groundwork for a versatile, time- and energy-efficient m

28 These results lay the groundwork for AAV-mediated gene therapy experiments in

29 These studies lay the groundwork for an improved mechanistic understanding of

30 This study lays the groundwork for an understanding of the mechanisms of the

31 This study provides the groundwork for analysis of the binding kinetics of longe

32 Here we establish a theoretical groundwork for analyzing protein thermodynamics using si

33 s to a relatively simple system, it lays the groundwork for application to biologically important com

34 ibutes of monolayer graphene resonators, the groundwork for applications of these devices, including

35 This system lays the groundwork for applications to an environmentally friend

36 Here we lay the groundwork for appreciating the mechanisms and consequen

37 h residual kinesthetic sense and provide the groundwork for augmenting cortically controlled BMIs wit

38 luation and medical optimization provide the groundwork for best medical practice in an otherwise hig

39 develop over long time periods and lays the groundwork for by using RNAi in phenotype-based, forward

40 This study begins to lay the groundwork for calculating pediatric IOL power in catara

41 This provides the groundwork for calculation of regional myocardial oxygen

42 of this slit diaphragm protein and lays the groundwork for characterizing the interactions between k

43 regulation of Rab12 activation and lays the groundwork for characterizing the regulation of other DE

44 therapeutic approaches for CMT1A and lay the groundwork for clinical trials in humans afflicted with

45 nocot angiosperms, and lays the phylogenetic groundwork for comparative analyses of the drivers and c

46 dules with tissue-specific activity lays the groundwork for complete characterization and deciphering

47 These results lay the groundwork for continued translational development of th

48 ty of the real-time intervention, laying the groundwork for controlled trials with larger sample size

49 These studies lay the groundwork for correlating defects in different Dhc gene

50 These findings laid important groundwork for current in-vivo studies on the role of fi

51 n rodents across the lifespan, providing the groundwork for deciphering disease mechanisms and develo

52 s important for hippocampal CaCC, laying the groundwork for deciphering the dynamic CaCC modulation o

53 This study lays the groundwork for detailed investigations of the mechanisms

54 The present study lays the groundwork for developing a systematic and automated met

55 g a simple, cost-effective means and lay the groundwork for developing additional highly sensitive bi

56 This research lays the groundwork for developing an alternative in situ remedia

57 These observations lay the groundwork for developing cardiospheres as a novel off-t

58 This comparative study lays the groundwork for developing improved tools and formalized

59 Taken together, these results lay the groundwork for developing new diagnostics and individual

60 The discovery of CER9 lays new groundwork for developing novel cuticle-based strategies

61 This study lays the groundwork for development of a diagnostic test that can

62 erences among prokaryotic SODs, and lays the groundwork for development of antimicrobial drugs that s

63 This establishes groundwork for development of molecular MR imaging-guide

64 cancer target, and our studies could lay the groundwork for development of novel cancer therapeutics.

65 from this study are important for laying the groundwork for discovery and design of high-affinity lig

66 interneuron subtypes, these studies lay the groundwork for elucidating the molecular bases for their

67 of a common polymorphism of CFH and lays the groundwork for elucidating the role of CFH in AMD pathog

68 These innovations provide the groundwork for enabling enhanced and more natural fine m

69 Numerous legal precedents have laid the groundwork for end-of-life decision making.

70 The results provide the groundwork for energy policies focused to maximize socio

71 al type II polyketide synthases and lays the groundwork for engineered biosynthesis of new bioactive

72 To lay a groundwork for engineering novel barrel proteins, we inv

73 Our studies lay the groundwork for epigenetic modification and mechanistic s

74 The results lay the groundwork for establishing a novel animal model and a n

75 Our findings lay the groundwork for establishing gene expression profiles tha

76 in nutrient absorption in vivo and lays the groundwork for examining integrated acid-base physiology

77 lish plaque stability, these studies lay the groundwork for exploration of mechanisms by which gap ju

78 e for activated astrocytes in AD and lay the groundwork for exploration of other novel astrocyte-base

79 efine this class of noncoding RNAs, lays the groundwork for functional studies, and provides the tool

80 ni-, bi- and multivariate scales and lay the groundwork for further clinical studies that might lead

81 This ability lays the groundwork for further enhancing the assay throughput by

82 Together, the results of this study lay the groundwork for further evaluation of mechanisms underlyi

83 This paper set the groundwork for further evaluation of the input of other

84 This study provides the groundwork for further exploration into the application

85 ities in this model, and lay the mechanistic groundwork for further improvements in this gene therapy

86 monary bacterial infections and provides the groundwork for further investigation into SPMs as altern

87 Our analysis lays the groundwork for further molecular studies of lung adenoca

88 HFGP studies presented in this issue lay the groundwork for further studies aimed at understanding th

89 une subphenotype may exist in MS and lay the groundwork for further studies focusing on the pathogeni

90 Our insights lay the groundwork for further studies of CNbeta1, whose physiol

91 t model for giant phage research, laying the groundwork for future analyses of their highly unusual v

92 the auditory pathway in rodents and lays the groundwork for future applications of cochlear optogenet

93 These results provide the groundwork for future behavioral studies.

94 Our study provides the groundwork for future characterization of ARE-binding pr

95 important class of antibiotics and sets the groundwork for future combinatorial biosynthesis for new

96 Our results provide groundwork for future development of clinical protocols

97 r function and hepatic steatosis, laying the groundwork for future diagnostic and therapeutic applica

98 These studies lay the groundwork for future enzyme engineering to broaden the

99 These studies provide the groundwork for future improvements in device design.

100 This work provides important groundwork for future in-depth studies of VF dynamics an

101 Our results provide important groundwork for future investigations of predator-prey dy

102 This study lays the groundwork for future investigations to identify the mol

103 that provides proof of concept and lays the groundwork for future investigations.

104 ity of primary mouth formation, and lays the groundwork for future molecular analyses of this importa

105 This study lays the groundwork for future molecular studies of Apis neuropep

106 This study lays the groundwork for future pHis proteomics studies in bacteri

107 This study lays the groundwork for future research related to the environmen

108 The results of these studies lay the groundwork for future strategies to therapeutically expl

109 These results lay the groundwork for future structural and functional dissecti

110 re anti-HBs seroconversion and represent the groundwork for future studies aimed at assessing whether

111 mechanisms of iNOS dimerization and lays the groundwork for future studies aimed at modulating iNOS a

112 These results lay the groundwork for future studies aimed at understanding the

113 ession and metastasis, these results lay the groundwork for future studies assessing the therapeutic

114 ng with structural insight provides critical groundwork for future studies for the family of AMPylato

115 with detoxification genes and lay important groundwork for future studies in the field of evolutiona

116 t, long-range spin interactions and lays the groundwork for future studies of many-body dynamics in s

117 This work lays the groundwork for future studies on the functional roles of

118 er, the results of these two studies lay the groundwork for future studies to determine how, in the f

119 these mutant p53 knock-in mice has laid the groundwork for future studies to elucidate the in vivo p

120 Together, the results of this study lay the groundwork for future studies to explore the role of DNA

121 rease gene targeting efficiency and lays the groundwork for future studies using aptamers for gene ta

122 This report provides the groundwork for future studies using IP CsA, both as a ch

123 y applied to study PNS disorders and lay the groundwork for future therapeutic application of optogen

124 ica in response to infection and provide the groundwork for future virulence studies.

125 These results lay the groundwork for identifying genes responsible for the ear

126 These results lay the groundwork for identifying the Dice1.1 and Dice1.2 genes

127 ism at the TI-FMI interface but also lay the groundwork for imaging magnetic domains and domain bound

128 This review sets the groundwork for implementing a value-based, patient-cente

129 to unlock this riddle, however, and lay the groundwork for improved cancer therapies.

130 These studies lay the groundwork for incorporating the effects of grouping int

131 l constituents of the human gut will set the groundwork for interpreting how the gastrointestinal mic

132 It also lays a groundwork for investigating the role of DE-cadherin in

133 To lay groundwork for investigating unequal divisions in the le

134 l characterization of EGF816 and provide the groundwork for its current evaluation in phase I/II clin

135 Our work lays the groundwork for label-free drug screening in pharmaceutic

136 The data presented here lay the groundwork for mapping the location of one of the sites

137 This work lays the groundwork for mechanistic and structural analysis of GT

138 These results lay the groundwork for mechanistic/deconstruction experiments to

139 Finally, our methodology provides the groundwork for more chemically detailed investigations o

140 This study lays the groundwork for more comprehensive models that can handle

141 all formation, and cell polarity, laying the groundwork for more detailed investigations on the funct

142 Overall, these results lay the groundwork for more detailed studies of venom function a

143 The results lay a conceptual groundwork for more effective studies of heterogeneity a

144 t into RV2 rhadinovirus biology and sets the groundwork for more intensive next-generation (Next-Gen)

145 detect single locus differences, laying the groundwork for mutation screens for new neuroexcitabilit

146 Our findings lay the groundwork for new applications of colloids and liquid c

147 er chronic degenerative diseases, laying the groundwork for new therapeutic strategies.

148 i flux in acute inflammation and provide the groundwork for novel anti-inflammatory strategies for tr

149 signaling during cardiac healing and provide groundwork for novel anti-inflammatory strategies in tre

150 al phase transition provide the experimental groundwork for opening the research on novel topological

151 Simple cells are thought to lay the groundwork for orientation selectivity.

152 systems biology perspective and provides the groundwork for other models that can be directly tied to

153 all these observations lay the groundwork for our understanding of how a noncontractile

154 hird-generation EGFR inhibitors will lay the groundwork for overcoming the next generation of resista

155 s for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale n

156 -dependent plasticity, these results lay the groundwork for probing microanatomical rearrangements th

157 erlie important cell functions is laying the groundwork for quantitative identification of protein-in

158 at regulate platelet function and to lay the groundwork for rational pharmacogenetic approaches.

159 This provides mechanistic groundwork for repurposing clinically approved JAK1/JAK2

160 hput rapidly increases, promising to lay the groundwork for revolutionizing our understanding of the

161 In addition, we set the groundwork for similar reciprocal inhibition approaches

162 cludes interactions and decoherence lays the groundwork for simulations of the transverse-field Ising

163 These studies lay the groundwork for strategies to target essential chaperone-

164 ion and dephosphorylation by CN and lays the groundwork for structure-based development of new CN inh

165 These measurements lay the groundwork for studying and exploiting spatial and tempo

166 scriptome of an expanding cell, and lays the groundwork for studying fundamental biological processes

167 ain recent experimental findings and lay the groundwork for studying the hierarchical molecular mecha

168 Here, we lay the groundwork for such a theory, starting with a key observ

169 ve long-range signaling pathways and lay the groundwork for systematic exploration of how induced-fit

170 ues that direct cleavage of CSF and laid the groundwork for testing whether other Phr peptides are pr

171 wo GluRS enzymes in one organism may lay the groundwork for the acquisition of the canonical glutamin

172 tent map of the critical region provides the groundwork for the construction of a transcription map a

173 This lays the groundwork for the construction of a transcriptional map

174 f simple biological systems may also lay the groundwork for the construction of more complex systems

175 This research lays the groundwork for the control of complex elastic deformatio

176 derstanding of this process while laying the groundwork for the creation of new chemical and biologic

177 nderstanding of protein folding and laid the groundwork for the creation of unprecedented structures

178 ticles and block copolymers, and it lays the groundwork for the design of cooperatively assembled fun

179 These results lay the groundwork for the design of effective Cry5B-based anthe

180 This work lays the groundwork for the design of ligand-based NP formulation

181 lum stress in myelinating cells has laid the groundwork for the design of new therapeutic strategies

182 me function, while simultaneously laying the groundwork for the design of novel catalysts.

183 tTGase in Celiac Sprue, our results lay the groundwork for the design of small molecule mimetics of

184 ross-inhibitor of PlasmodiumSUB1, laying the groundwork for the development of a globally active smal

185 These findings lay the groundwork for the development of assembly inhibitors as

186 ction, the results of this study may lay the groundwork for the development of effective clinical str

187 ls and highlight studies that are laying the groundwork for the development of effective therapeutic

188 mplified human genomic DNA samples, lays the groundwork for the development of high-density arrays ab

189 Therefore, our findings provide groundwork for the development of highly specific and sa

190 investigating lncRNAs in cancer and lays the groundwork for the development of new diagnostics and tr

191 orate in protein remodeling will provide the groundwork for the development of new therapeutic strate

192 d understanding its pathophysiology will lay groundwork for the development of new treatments.

193 ification of Notch target genes, and lay the groundwork for the development of Notch pathway inhibito

194 Gal-deficient IgA1 hinge region and lay the groundwork for the development of reliable diagnostic to

195 f siphovirus-mediated HGT, but also lays the groundwork for the development of sensitive affinity-bas

196 ueous conditions in high yield, and lays the groundwork for the development of sulfinic acid detectio

197 neurodegenerative diseases and establish the groundwork for the development of therapeutic strategies

198 ned from these studies contributed important groundwork for the eventual development of antiviral dru

199 This study lays the groundwork for the eventual identification of common TS

200 These results provide the groundwork for the experimental verification of the func

201 These data lay the groundwork for the exploration of EC therapies that can

202 association, thereby establishing important groundwork for the functional characterization of FtsB i

203 The results of this study lay the groundwork for the further evaluation of CAR-expressing

204 These findings provide a solid groundwork for the future application of this method for

205 This methodology constitutes the groundwork for the future development of a spray to dete

206 mutation with direct visualization laid the groundwork for the future development of detector-free t

207 have contributed to and laid the conceptual groundwork for the growth in the number of reports of di

208 Our data provide groundwork for the implementation of molecular ultrasoun

209 t molecules, the endeavor laid the important groundwork for the next-generation drives toward the CP-

210 This fundamental concept laid the groundwork for the notion of a modular sensory cortex, c

211 This study lays the groundwork for the on-going development of image-guided

212 ctural properties of chiral peptoids lay the groundwork for the rational design of more complex polyp

213 omal peptide synthetases (NRPSs) and lay the groundwork for the rational reengineering of NRPSs by sw

214 h miniaturized detection systems may lay the groundwork for the real-time, point-of-care detection of

215 These results lay the groundwork for the study of variation in sporulation eff

216 Therefore, these experiments lay the groundwork for the time course of differentiation, regen

217 Much of the groundwork for the understanding of mast cells was estab

218 r proteins and monogenic autism, and lay the groundwork for the use of mGlu5 receptor antagonists in

219 The groundwork for these changes began a decade ago with the

220 Our goal is to lay the groundwork for this technique and establish it as a new

221 uding the foundational efforts that laid the groundwork for today's investigations, and detail the mo

222 3 types of human breast cancers and lay the groundwork for translation of these measures to the clin

223 s unique to hvKP, which is needed to lay the groundwork for translational approaches to prevent or tr

224 gn criteria derived from this study lays the groundwork for ultrabright fluorescence bullets for in v

225 This finding lays the groundwork for understanding cell-based biological pacem

226 production--findings that ultimately lay the groundwork for understanding how more complex musical se

227 These data provide the groundwork for understanding the architecture of modulat

228 EMT in avian lip development lays important groundwork for understanding the causes of human cleft l

229 These results lay the groundwork for understanding the differential sensitivit

230 and pathways associated with OS, and set the groundwork for understanding the functions of OS-related

231 physical data, these results lay the initial groundwork for understanding the genetic processes respo

232 Collectively, our study lays the groundwork for understanding the molecular basis of a ke

233 Simple perceptual tasks have laid the groundwork for understanding the neurobiology of decisio

234 In doing so, we lay the groundwork for understanding these elaborate protein com

235 These studies have laid the groundwork for unraveling new enzymatic strategies for d

236 Our results lay the groundwork for using a phylogenetic approach to correct

237 This study lays the groundwork for using alkaline-earth atoms as testbeds fo

238 to an arbitrary reference frame, laying the groundwork for using backbone residual dipolar couplings

239 arcoma clinical characterization and lay the groundwork for using Boolean-based probabilities to iden

240 Our results lay the groundwork for using fermionic optical lattice clocks to

241 nfected fish to healthy fish, which lays the groundwork for using LJ001 as a possible therapeutic for

242 hysiological function of PrP(C), and lay the groundwork for using PrP-expressing yeast to study other

243 Nevertheless, the groundwork has been created for a new class of boron-con

244 These preliminary results lay the groundwork in determination of potential roles for a neg

245 Moreover, groundwork in this area using engineered protein nanopor

246 ng knowledge gleaned from the aforementioned groundwork, including stem cell transplantation, likely

247 egies for therapy are not yet available, the groundwork is being laid for cell or gene therapy.

248 Thus the groundwork is being laid for researchers to exploit exis

249 This work lays the critical groundwork necessary to access even higher oxidized taxa

250 craniofacial complex in baboons provides the groundwork needed to establish the baboon as an animal m

251 This study provides the groundwork needed to uncover the correlation among oxida

252 These results lay the groundwork needed to understand the structure of the CA-

253 These results provide the valuable groundwork required to further understand how Nature cod

254 Our research contributes to the groundwork studies to determine the geographical origin

255 will result in a more thorough model of the groundwork the human brain was built upon.

256 data tables presented provide the scientific groundwork to assist physicians and other policy-makers

257 This lays the groundwork to design longer, and therefore stickier, off

258 tarvation and recovery, and lays the initial groundwork to develop Methyloprofundus as a model chemos

259 and validated that establishes the necessary groundwork to enable large population-based assessments

260 lpha-syn lysosomal degradation, establishing groundwork to explore mechanisms to enhance their cellul

261 at this noncovalent interaction provides the groundwork to explore molecular mechanisms linking PD wi

262 mitochondrial apoptotic p53 program lays the groundwork to further investigate its efficacy and safet

263 e challenging, recent advances have laid the groundwork to initiate these biotechnological solutions

264 directly in a biological matrix, laying the groundwork to perform in vivo measurements in a near fut

265 proaches like this will be useful to lay the groundwork to reconstruct regulatory networks on the lev

266 f early functional adaptations could lay the groundwork to test therapeutic interventions that halt o

267 As such, they provide initial groundwork toward understanding how ER stress sensors ca