ライフサイエンスコーパス: growth control

1 properties, which impacts on E2F-1-dependent growth control.

2 as a negative regulator of Fat signaling in growth control.

3 wound protection, tube expansion and larval growth control.

4 eostatic feedback so as to favor escape from growth control.

5 ormalization of both p57-Kip2 expression and growth control.

6 hormone pathways both contribute to diurnal growth control.

7 uperfamily, is known to play a major role in growth control.

8 urther dissect the molecular basis for tumor growth control.

9 idespread roles for promoter lncRNAs in cell-growth control.

10 ponent of the Hippo pathway in imaginal disk growth control.

11 wth, suggesting a unique function other than growth control.

12 gulated MAPK and Rho GTPase signaling in NF2 growth control.

13 TOR) plays a central role in eukaryotic cell growth control.

14 and cyclin D1 playing key roles in MRT cell growth control.

15 ient availability, Ribi gene regulation, and growth control.

16 te immunity and deregulate p53-mediated cell growth control.

17 as uncovering a function for Smad8 in normal growth control.

18 by 28%, suggesting a role for IGF-1 in brain growth control.

19 s but has not been shown to function in cell-growth control.

20 strain-mediated effects on endothelial cell growth control.

21 bstrates of AMPK that mediate its effects on growth control.

22 late insulin signaling and thus exert global growth control.

23 tory pathways that are critical for cellular growth control.

24 which JunD exerts a pivotal role in cellular growth control.

25 ulation of ErbB2-dependent Src signaling and growth control.

26 XW8-CUL7 complex plays a significant role in growth control.

27 utant have normal intestines without loss of growth control.

28 ed TSC signalling as a conserved pathway for growth control.

29 ic link between cell fate, proliferation and growth control.

30 s screening strategy for studying epithelial growth control.

31 llular programs, such as differentiation and growth control.

32 Warts and the significance of these links to growth control.

33 erse array of processes involved in cellular growth control.

34 an important role in host defense and tumor growth control.

35 ctor proteins in TGFbeta-mediated pancreatic growth control.

36 rete cellular signaling pathways involved in growth control.

37 rial calcification, signal transduction, and growth control.

38 h and Wnt signaling pathways in keratinocyte growth control.

39 s development, differentiation, and cellular growth control.

40 roles in inhibiting other proteinases and in growth control.

41 emonstrated a critical role for dMyc in cell growth control.

42 esting a link between TAF9 function and cell growth control.

43 F9 involvement in cell cycle progression and growth control.

44 kinase that plays an essential role in cell growth control.

45 t should be 80% inhibition compared with the growth control.

46 erse array of processes involved in cellular growth control.

47 signaling machinery that is responsible for growth control.

48 rylation following deregulation of normal Rb growth control.

49 chanistic descriptions of the cell cycle and growth control.

50 ecies (ROS) by the NADPH oxidase to cellular growth control.

51 uggesting important roles in development and growth control.

52 role in malignant transformation and/or cell growth control.

53 ude and range of Hh signaling, and disrupted growth control.

54 l-cell interaction, signal transduction, and growth control.

55 2 in adipogenesis, osteogenesis, and general growth control.

56 ning and memory, and mammary epithelial cell growth control.

57 reading of 80% inhibition as compared to the growth control.

58 on glycolytic commitment independent of cell growth control.

59 reading of 80% inhibition as compared to the growth control.

60 could provide a novel feedback mechanism for growth control.

61 fying the molecular mechanisms that underpin growth control.

62 tional phenotype, resulting in better tumour growth control.

63 bblestone appearance, Yap1 localization, and growth control.

64 the inherent limitations of surfactants for growth control.

65 target gene domains as well as DPP's role in growth control.

66 hway is essential for development and tissue growth control.

67 ge between the small GTPases RhoA and Rac in growth control.

68 nserved tRNA nucleotide modification in cell growth control.

69 lved in both pleiotropic drug resistance and growth control.

70 s have been implicated in the SWH network in growth control [5-8].

71 ng to a functional equilibrium important for growth control, a reservoir of P-TEFb is maintained in a

72 reading of 50% inhibition as compared to the growth control and 88 to 99% agreement at a visual endpo

73 reading of 50% inhibition as compared to the growth control and 96% agreement at a visual endpoint re

74 at has important implications for studies of growth control and adult progenitor/stem cell population

75 cell cycle inhibition, restores endothelial growth control and arterial gene expression.

76 ole of insulin-like growth factor (IGF)-1 in growth control and bone mineralization, circulating IGF-

77 ns of the observed difference between normal growth control and cancer for drug development, and the

78 n > liposomal doxorubicin) of improved tumor growth control and decreased viable tumor compared with

79 issue, we explored the role of eIF2alpha in growth control and demonstrated that the eIF2alpha-S51A

80 es a homeostatic mechanism balancing HPC/HSC growth control and differentiation decisions in response

81 amily of transcription factors that regulate growth control and differentiation of various tissues.

82 onal repressor involved in the regulation of growth control and DNA damage response.

83 that Zyx is a functional antagonist of Ex in growth control and establish a link between actin filame

84 ected at promoters of genes involved in cell growth control and genomic stability.

85 ent mechanisms for mTOR-dependent glial cell growth control and gliomagenesis relevant to the design

86 connections of MYST proteins to development, growth control and human cancers.

87 ular communication correlates with decreased growth control and increased neoplastic potential, there

88 ncRNA has been implicated in development and growth control and is associated with human genetic diso

89 hway signaling plays a critical role in cell growth control and is often upregulated in human cancer.

90 The p53-MDM2 feedback loop is vital for cell growth control and is subjected to multiple regulations

91 PIP(3) has many cellular roles, notably in growth control and macropinocytosis as well as cell moti

92 As such, their role in cellular growth control and malignant transformation has been the

93 ides an improved theoretical basis for tumor growth control and may also find utility in therapeutic

94 biology involving cellular differentiation, growth control and morphogenesis.

95 c consequences that include loss of cellular growth control and neoplastic transformation.

96 raded will enhance our understanding of cell growth control and offer a basis for potential therapeut

97 ges of limb regeneration share mechanisms of growth control and patterning with limb development, the

98 F complexes, are important for developmental growth control and patterning, with direct function as a

99 understanding of interrelationships between growth control and phenotype commitment.

100 and developmental processes, including cell-growth control and programmed cell death.

101 of Foxo and inducing its targets, including growth control and stress defense genes.

102 Phytohormones act in the integration of growth control and stress response, but their role in pl

103 are functionally required for Hippo-mediated growth control and target gene expression.

104 ty comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pat

105 These data suggest that GATA3 is involved in growth control and the maintenance of the differentiated

106 y implications of these results for graphene growth control and their relevance to carbon nanotube gr

107 2 in Schwann cells leads to loss of cellular growth control and tumor formation.

108 ata thus link a general elongation factor to growth control and tumorigenesis.

109 is novel YAP function may contribute to cell growth control and tumorigenesis.

110 a subset of proteins required for embryonic growth control and vessel development.

111 To provide a growth-controlled and immune protective environment with

112 Y also coassociates with a select cluster of growth-controlling and oncogenic TFs, consistent with th

113 s have been implicated in metabolic control, growth control, and a variety of stress responses.

114 role in transcriptional regulation, cellular growth control, and cell-cycle progression.

115 g is essential for tumor suppression, tissue growth control, and development, while stable MOB1/Hippo

116 l processes, including developmental timing, growth control, and differentiation.

117 e that is important for antiviral responses, growth control, and modulation of immune responses.

118 yte organization and differentiation, oocyte growth control, and oocyte nuclear migration.

119 ly time points, often near genes involved in growth control, and several patients harbored expanded c

120 ating p53- and E2F1-dependent cell survival, growth control, and stress responses.

121 c-myc oncogene plays a key role in cellular growth control, and translation initiation factors are a

122 GADD45beta, which is known to influence cell growth control, apoptosis, and cellular response to DNA

123 iruses, tumorigenesis and metastasis, cancer growth control, apoptosis, and senescence.

124 possible roles of toxin-antitoxin modules in growth control are explored, as well as other mechanisms

125 ption of epithelial organization and loss of growth control are universal features of carcinomas, yet

126 mic models that show how self-monitoring and growth control arise from the synthesis of cellular acti

127 Consistent with a role for these changes in growth control, artificially increasing extracellular pH

128 d apoptosis, which may be linked to cellular growth control as well as tumor suppression.

129 er cells are refractory to TGF-beta-mediated growth control because of the reduced expression of TGF-

130 We thus link a morphological transition in growth control between allometric and isometric growth m

131 ss response, such as defense against phages, growth control, biofilm formation, persistence, and prog

132 from test bottles and 96.9% of strains from growth control bottles (no antibiotic added), and the BA

133 s from test bottles and 100% of strains from growth control bottles.

134 This growth controls buckling instability, which triggers the

135 r Capping proteins, are essential for proper growth control by affecting Hippo signalling.

136 h AMs significantly (p < 0.05) increased Mtb growth control by AMs.

137 ts provide fresh insight on the mechanism of growth control by androgens and the progression of prost

138 Importantly, intramacrophage LVS growth control by CD8(+) T cells, but not CD4(+) T cells

139 eregulate host antiviral innate immunity and growth control by incorporating four viral homologs (vIR

140 , key signaling pathways are dispensable for growth control by Runx2.

141 Thus, growth control by the Dpp morphogen gradient remains und

142 Furthermore, the mutant, growth controlled by abscisic acid (gca2) shows impairme

143 ce between calcite dissolution and cerussite growth controlled by adjusting the Pb(2+) concentration

144 Prostate organogenesis involves epithelial growth controlled by inductive signalling from specialis

145 spinal neuron, we build models of their axon growth controlled by simple chemical gradients and physi

146 We report that DELLA-dependent growth control can be regulated independently of GA.

147 gical functions, including organogenesis and growth control, cell adhesion, signaling, inflammation,

148 en shown to play important roles in cellular growth control, cell cycle progression, and cancer devel

149 coded by an imprinted gene that has roles in growth control, cellular proliferation, and insulin sign

150 connected pathways suggests that the loss of growth-control checkpoints and promotion of cell surviva

151 rovide a regulatory feedback signal into the growth control circuit.

152 o affect both cell division control and cell growth control coincides with myc's remarkable effects o

153 n oncogene to escape normal cell response to growth-controlling cytokines.

154 In epithelial tissues, growth control depends on the maintenance of proper arch

155 c-MYC has a pivotal function in growth control, differentiation and apoptosis, and its a

156 nt signaling paths are involved in dendritic growth control downstream of BMPR1A/B.

157 o important mechanisms for Hpo activation in growth control during animal development.

158 ranscripts that are crucial in apoptosis and growth control during normal development.

159 We have revealed a critical transition in growth control during zebrafish caudal fin development,

160 hway is essential for development and tissue growth control, encompassing a core cassette consisting

161 structures provide great flexibility through growth-controlled 'engineering' of electron and hole wav

162 ncluding increased angiogenesis, deregulated growth control, enhanced cellular survival, epithelial-t

163 ncy of the clone may be regulated in part by growth controls extrinsic to the tumor cells.

164 ility of these lesions may in part be due to growth controls extrinsic to tumor cells.

165 ed by perturbations of renal epithelial cell growth control, fluid transport, and morphogenesis.

166 s and highlight the importance of NDRG1 as a growth control gene in breast tissue.

167 F1 SUMOylation, leading to activation of the growth-control gene program.

168 argely autonomous behavior of another tested growth-control gene, we find that KLUH activity extends

169 TBX2 has previously been shown to repress growth control genes such as p14(ARF) and p21(WAF1/cip1)

170 ntify coordinately expressed prostate cancer growth control genes that may be regulated by WT1, we us

171 pediments to axon regrowth, we analyzed cell growth control genes using a virus-assisted in vivo cond

172 Conversely for two prostate growth control genes, androgen receptor (AR) and vascula

173 nerally attributed to mutations in essential growth control genes, but tumor cells are also affected

174 of chromosomes, with some located in or near growth control genes, including the c-myc protooncogene

175 of BaP, with subsequent mutation of critical growth control genes.

176 ycomb 2 protein (Pc2) controls relocation of growth-control genes between Polycomb bodies (PcGs) and

177 st that transcriptional deregulation of G1/S growth-control genes, mediated in large part through blo

178 /T-cell factor interaction and alteration of growth-controlling genes such as c-MYC and cyclin D1.

179 f epigenetic defects as well as mutations in growth-controlling genes that seem to tip the proliferat

180 kely to encode proteins directly involved in growth control, have remained elusive.

181 ignaling pathway plays a major role in organ growth control, how it senses and responds to increased

182 the BH3 mimetic obatoclax improves lymphoma growth control in a primary PTCL ex vivo culture and in

183 ere determined as potential mediators of Mtb growth control in AMs and AM/CD8 and AM/CD4 cocultures.

184 Growth control in animals and plants involves mobile sig

185 Comparison to ROS-regulated growth control in animals suggests that a similar mechan

186 egulated cell viability and was required for growth control in chronically proliferating GCs.

187 of its signaling pathway result in a loss of growth control in chronically stimulated mucosal GCs.

188 e FAK overexpression-induced growth, loss of growth control in FAK-/- or FRNK-expressing cells increa

189 whether altered HSPGs contribute to loss of growth control in gliomas.

190 CD4 T cells did not increase Mtb growth control in HHCs or in CCs.

191 the specific roles of PKCbeta1 and beta2 in growth control in human breast cancer cell lines.

192 Manduca sexta larvae are a model for growth control in insects, particularly for the demonstr

193 s issues of lifespan, cancer metabolism, and growth control in more complex organisms.

194 tant insights into the cellular mechanism of growth control in plants.

195 is one mechanism that defines the absence of growth control in prostate cancer.

196 re necrotic lung lesions, more efficient Mtb growth control in the lungs, and longer survival.

197 lipid-based signaling, energy metabolism and growth control in the plant response to ROS and water st

198 ROCK inhibition rescued adhesion-dependent growth control in these cells, and expression of constit

199 hat T. congolense exhibits density-dependent growth control in vivo and conserves QS regulatory genes

200 To directly test the role of Sulfs in tumor growth control in vivo, a human myeloma cell line was tr

201 ether it makes a significant contribution to growth control in vivo, and how it is modulated and expe

202 These data describe a novel mechanism of growth control in which a ligand-receptor system generat

203 cancer cells and functions in bypassing cell growth control, including the repression of the cell cyc

204 packaging, Csk is dispensable for ring canal growth control, indicating that distinct mechanisms cont

205 that the downregulation of p53-mediated cell growth control is a common characteristic of the four KS

206 In various tumors inactivation of growth control is achieved by interfering with the RB1 s

207 Nanoscale crystal growth control is crucial for tailoring two-dimensional

208 IBPs are useful in applications where ice growth control is necessary, such as cryopreservation, f

209 The proposed mechanism of growth control is not specific to imaginal disc growth a

210 Loss of cell growth control is not sufficient to explain why tumours

211 A key component of growth control is the protein kinase Akt, which acts dow

212 demonstrate that the Sse1 chaperone and the growth control kinase Sch9 independently contribute to r

213 moting DNA binding landscape of Meis1 to the growth-controlling landscape of Prep1.

214 se with an important role in regulating cell growth, controls lipid biosynthesis through various mech

215 Despite prominent roles in growth control, little is known about the signals that r

216 y mTOR and autophagy is a novel mechanism of growth control, matching YAP activity with nutrient avai

217 indicating that this aspect of human B cell growth control may differ in mice.

218 that target this infraribosomal mode of cell growth control may shape future clinical progress.

219 nistic links between cellular metabolism and growth control may ultimately lead to better treatments

220 piration, which suggest that a Fat1-mediated growth control mechanism is intrinsic to mitochondria.

221 r regeneration, and this suggests a critical growth control mechanism mediated by these transcription

222 s and identify an important IGF-IR-dependent growth control mechanism.

223 (The preservation of normal growth control mechanisms and an absence of tumorigenic

224 w these photosensory pathways integrate with growth control mechanisms to achieve the appropriate deg

225 Cell growth control mechanisms were studied based on organiza

226 ral to efforts aimed at elucidating prostate growth control mechanisms.

227 may reflect the actions of vision-dependent, growth-control mechanisms operating over a wide area of

228 cells retain at least some of the essential growth-control mechanisms used by wild-type germ cells.

229 re, are a valuable source of information for growth-controlling mechanisms.

230 ate generic processes such as cell-cycle and growth control, metabolic pathways, and apoptosis.

231 Both structures are growth-controlled modifications that influence sensitivi

232 TOR protein kinase has emerged as a critical growth-control node, receiving stimulatory signals from

233 Unexpectedly, PMN recruitment and tumor growth control occurred independently of lymphocytes and

234 microdomains plays an essential role in the growth control of epidermal cells, including cancer cell

235 inhibitors by autocrine TGF-beta leading to growth control of ER(+) breast cancer cells.

236 0 chaperones as signal transducers mediating growth control of G1 cyclin abundance and activity.

237 sor genes that have fundamental roles in the growth control of hematopoietic stem/progenitor cells (H

238 r the cell cycle inhibitor p21(Waf1/Cip1) in growth control of HMECs and extend the repertoire of miR

239 olved mechanisms that can interfere with the growth control of infected cells and force them into DNA

240 nhanced antitumor CD8 T responses leading to growth control of injected and contralateral tumors in m

241 nce in the cells and have been implicated in growth control of normal and malignant cells.

242 alyses have led to a better understanding of growth control of prostate cancer cells.

243 Besides being a crucial factor in the growth control of roots and shoots, ethylene can promote

244 he Imprinted Gene Network (IGN), involved in growth control of the embryo.

245 shed that vitamin D participates in negative growth control of the normal mammary gland and that disr

246 We have specifically addressed whether growth control of the skeleton by IGFs interacts genetic

247 fficient to regulate flowering time and root growth; control of cotyledon and hypocotyl growth requir

248 Our theory delineates the geometric and growth control parameters that determine the shape space

249 ral role in signaling disturbances in the Rb growth control pathway and, by upregulation of Chk2, may

250 otein 4.1B/DAL-1 regulation of this critical growth control pathway in meningioma cells requires the

251 1, a component of the insulin receptor (InR) growth control pathway.

252 le, p185/Cul7 may also regulate an important growth control pathway.

253 How the numerous growth control pathways are coordinated by the ethylene

254 esults suggest the manipulation of intrinsic growth control pathways as a therapeutic approach to pro

255 le is presently known about the dysregulated growth control pathways involved in their formation and

256 ne kinase signaling, intracellular mitogenic growth control pathways, or adherens junction organizati

257 as a consequence of the failure of conserved growth control pathways.

258 othesize additional physiological changes in growth control pathways.

259 int to evaluate interactions between AHR and growth-controlling pathways.

260 tional negative regulator of Ft signaling in growth control, PCP, and appendage patterning, the Appro

261 It is possible that deregulation of cellular growth control plays a more important role in epilepsy t

262 ta1, in addition to its role in homoeostatic growth control, plays a complex role in regulating respo

263 photosynthesis form an integral part of this growth control process, acting as both an energy source

264 c program of messenger RNAs involved in cell growth control processes, including cell cycling, differ

265 al cues to elicit critical outputs including growth control, protein synthesis, gene expression, and

266 d rat and included genes encoding cell-cycle/growth control proteins, transcription factors, signal t

267 , the feather provides a rich model to study growth control, regeneration, and morphogenesis in vivo.

268 previously unappreciated mechanism involving growth control regulates Met4.

269 Despite its importance in cell polarity and growth control, relatively little is known about how aPK

270 es, it is likely that many genes involved in growth control remain to be discovered.

271 of this auto-/paracrine signaling module in growth control remains poorly understood.

272 of geometries that may minimize the level of growth control required for survival.

273 for improving chemotherapeutic and/or tumor growth control responses in pancreatic cancer.

274 Consistent with a negative role in cell growth control, Rga4p protein localizes to the cell side

275 lyze cell-autonomous and non-cell-autonomous growth control roles of NS3 in Drosophila and demonstrat

276 tion channels play an important role in cell growth control, secretion and embryonic development.

277 implicate Warts as an integrator of multiple growth control signals.

278 nderstanding of endogenous and environmental growth-controlling signals and their signaling networks,

279 t work on p21 has illuminated basic cellular growth control, stem cell phenotypes, the physiology of

280 The molecular biology of the CNS growth control system has remained, for the most part, e

281 cascade of chemical signals constitutes this growth control system.

282 Interestingly, NF-Y and several growth-controlling TFs bind in a stereo-specific manner,

283 nd IL-17A affected significantly greater LVS growth control than treatment with either cytokine alone

284 proliferation is an essential part of organ growth control; the transcription coactivator Yes-associ

285 mammalian D-type cyclins participate in cell growth control through negative regulation of TSC1-TSC2

286 it is required to maintain cell polarity and growth control through PAR-1 and AMPK, respectively.

287 uppressor that couples bioenergetics to cell-growth control through regulation of mammalian target of

288 a central regulator of tumor metabolism and growth control through the regulation of HIF-1alpha-depe

289 of the signaling pathways important for size/growth control, together with the identification of dise

290 tributions of Fos to the cell cycle and cell growth control using Drosophila imaginal discs as a gene

291 ortant implications for nutrient sensing and growth control via mTor pathways in metazoans.

292 However, an endocrine role of IGF1 in growth control was disputed on the basis of the results

293 etectable contribution of CD8 T cells to Mtb growth control was observed.

294 and DNA synthesis and between p170 and cell growth control, we investigated in this study whether p1

295 ture of human overgrowth syndromes and human growth control, we performed experimental and bioinforma

296 gamma and nitric acid concentrations and Mtb growth control were not correlated.

297 Bex3 expression and possible function in growth control were studied.

298 We investigate different types of growth control which range from "division-controlled" to

299 s of nanoparticles, the nanoparticle-enabled growth control will find broad applications.

300 quence of cumulative disruptions to cellular growth control with Darwinian selection for those herita