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1  for moxonidine versus -13.5+/-1.9 mm Hg for guanabenz).
2 e also excited by norepinephrine (50 ng) and guanabenz (10 microg) but not by clonidine (3 microg) or
3                                              Guanabenz, a metabolism-based irreversible inactivator o
4 gically Active Compounds and discovered that Guanabenz acetate (Wytensin), an FDA-approved drug forme
5 , experimental autoimmune encephalomyelitis, guanabenz alleviates clinical symptoms, which correlates
6                                    Moreover, guanabenz ameliorates relapse in relapsing-remitting exp
7                                              Guanabenz, an alpha2-agonist, prolonged baseline expirat
8 in vivo, we have investigated the effects of guanabenz and N(G)-nitro-L-arginine in HEK 293 cells sta
9  have used two mechanism-based inactivators, guanabenz and NG-amino-L-arginine, to alter the heme/sub
10  The [(o-chlorobenzylidene)amino]guanidines (Guanabenz and Sephin1) have been proposed to exert prote
11 ee specific compounds, namely valproic acid, guanabenz, and a specific Caspase12 inhibitor, achieved
12  the alpha2-adrenoceptor (alpha2-AR) agonist guanabenz, but not by the Ih-imidazoline receptor agonis
13                            We show here that guanabenz, but not N(G)-nitro-L-arginine, caused the ina
14 ver pure alpha(2)-adrenergic agonists (i.e., guanabenz) due to its lowered incidence of sedative side
15 ioral effects of low doses of moxonidine and guanabenz in C57Bl/6 mice in an exploratory arena.
16  stress response using the FDA-approved drug guanabenz increases oligodendrocyte survival in culture
17 ompared to saline-injected controls; whereas guanabenz induced only dose-responsive sedative-like beh
18  complex and constitutive protein synthesis, guanabenz prolonged eIF2alpha phosphorylation in human s
19 by inhibition of Gadd34-PP1 phosphatase with guanabenz protects oligodendrocytes and partially rescue
20                We describe a small molecule, guanabenz, that bound to a regulatory subunit of protein
21 er signaling cascade, it was possible to use guanabenz to dose-dependently control expression of GLP-
22                                     In vivo, guanabenz treatment protects against oligodendrocyte los
23 AR involvement, the sedative-like effects of guanabenz were completely blocked by pretreatment with t
24 he clinically licensed antihypertensive drug guanabenz (Wytensin) activates a synthetic signal cascad

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