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1 ry as analogues of spiroiminodihydantoin and guanidinohydantoin.
2 -deoxynucleoside-5'-triphosphate (dSpTP) and guanidinohydantoin-2'-deoxynucleoside-5'-triphosphate (d
4 yribonucleosides of spiroiminodihydantoin, 5-guanidinohydantoin, and oxazolone resulting from H2O as
6 uanine (dOG), spiroiminodihydantoin (dSp), 5-guanidinohydantoin (dGh), oxazolone (dZ), 5-carboxamido-
7 ation products include potentially mutagenic guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) b
8 r ability to remove oxidized guanine lesions guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) f
9 droxy-7,9-dihydropurine-6,8-dione (5-OH-OG), guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) f
10 ptibility to further oxidation that produces guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) l
11 to secondary oxidation products, such as the guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) n
12 e lesions 8-oxo-7,8-dihydroguanine (8-oxoG), guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) r
13 to the formation of hydantoins, specifically guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp),
14 ent work has identified two new DNA lesions, guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp),
16 ty of oxidants yields the hydantoin lesions, guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp).
17 ro to form two secondary oxidation products, guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp).
18 s further oxidation products, the hydantoins guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp).
20 -2'-deoxyguanine (8-oxoG) oxidation products guanidinohydantoin (Gh) and the two stable stereoisomers
21 of synthesis, the oxidation products of OG, guanidinohydantoin (Gh) and/or its isomer iminoallantoin
22 in products spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh) in a sharply pH-dependent fashio
23 rther oxidation of 8-oxoG can produce either guanidinohydantoin (Gh) in duplex DNA or spiroiminodihyd
25 xidized purines, spiroiminodihydantoin (Sp), guanidinohydantoin (Gh), 2,6-diamino-4-hydroxy-5-formami
26 col (Tg), 8-oxo-7,8-dihydroguanine (8-oxoG), guanidinohydantoin (Gh), or spiroiminodihydantoin (Sp) c
27 ity of MutY on the 8-oxoG oxidation products guanidinohydantoin (Gh), two diastereomers of spiroimino
30 te that an oxidized form of 8-oxoG, possibly guanidinohydantoin, may direct misreading and misinserti
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