ライフサイエンスコーパス: guanine phosphoribosyltransferase

1 des the purine recycling enzyme hypoxanthine-guanine phosphoribosyltransferase.

2 sed by deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase.

3 lanation for the specificity of hypoxanthine-guanine phosphoribosyltransferase, a key enzyme in the p

4 Mutants deficient in hypoxanthine-xanthine-guanine phosphoribosyltransferase activity were used as

5 utant parasite lacking hypoxanthine-xanthine-guanine phosphoribosyltransferase and a T. gondii cDNA l

6 ynthesis and relies primarily on adenine and guanine phosphoribosyltransferases (APRTase and GPRTase)

7 inical features associated with hypoxanthine-guanine phosphoribosyltransferase deficiency.

8 s and diagnosis of all forms of hypoxanthine-guanine phosphoribosyltransferase deficiency.

9 Guanine phosphoribosyltransferase from Giardia lamblia,

10 The Escherichia coli xanthine-guanine phosphoribosyltransferase gene (Ecogpt) rescues

11 on of 8 x 10(-3) in the nuclear hypoxanthine-guanine phosphoribosyltransferase gene, and a clear and

12 ely stable mutation rate of the hypoxanthine-guanine phosphoribosyltransferase gene.

13 cell death and mutations at the hypoxanthine-guanine phosphoribosyltransferase gene.

14 The coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene was amplified by

15 adenine phosphoribosyltransferase (APRT) and guanine phosphoribosyltransferase (GPRT) that constitute

16 Guanine phosphoribosyltransferase (GPRTase) from Giardia

17 tains the selectable marker Escherichia coli guanine phosphoribosyltransferase (gpt) linked to a TGFb

18 Homozygous null mutants of the hypoxanthine-guanine phosphoribosyltransferase (hgprt) and adenine ph

19 to be good inhibitors of human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Plasmodium

20 d identity with the L. donovani hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and significan

21 vages purines primarily through hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and xanthine p

22 We here demonstrate that human hypoxanthine guanine phosphoribosyltransferase (HGPRT) converts T-705

23 complexes of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase (HGPRT) have been dete

24 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is a key enzym

25 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is the key enz

26 activity was determined at the hypoxanthine-guanine phosphoribosyltransferase (HGPRT) locus.

27 es of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) of the apicomp

28 Crystal structures of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) proteins have

29 To dissect the contributions of hypoxanthine-guanine phosphoribosyltransferase (HGPRT), adenine phosp

30 ucture of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase (HGPRT)-xanthosine 5'-

31 y of the purine salvage enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

32 or direct salvage of guanine by hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

33 of the purine recycling enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt).

34 HGXPRT) and Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

35 leoside phosphorylase (PNP) and hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) catalyze N-

36 Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) catalyzes t

37 e are similar to those of human hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) despite dis

38 Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) is the locu

39 lations on two enzymes: a human hypoxanthine-guanine-phosphoribosyltransferase (HGPRTase) and its ana

40 the purine biosynthetic enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) cause the intra

41 Somatic mutations in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene are rare o

42 onal promoter and exon 1 of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the mou

43 ced mutation frequencies at the hypoxanthine guanine phosphoribosyltransferase (HPRT) locus in diploi

44 sociated with cRSS sites at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in periph

45 rder caused by mutations of the hypoxanthine guanine phosphoribosyltransferase (HPRT) purine biosynth

46 mutations were detected in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) reporter gene i

47 Here we present the hypoxanthine-guanine phosphoribosyltransferase (HPRT) reporter gene m

48 guanine through the activity of hypoxanthine-guanine phosphoribosyltransferase (HPRT) to supply the c

49 somatic mutations (Mfs) at the hypoxanthine-guanine phosphoribosyltransferase (HPRT)-reporter gene i

50 cy of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

51 the X chromosome-linked enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

52 mphoblastoid cells in the human hypoxanthine-guanine-phosphoribosyltransferase (HPRT) gene and compar

53 These genes included those for hypoxanthine-guanine phosphoribosyltransferase (hpt), adenylosuccinat

54 defined by the enzymes hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) and adenosine

55 xpression of T. gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) in stable tra

56 tive selectable marker hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT).

57 with 17alpha or Yalpha and the hypoxanthine guanine phosphoribosyltransferase locus (HPRT1).

58 ransgene (Tg; inserted into the hypoxanthine-guanine phosphoribosyltransferase locus) that enables in

59 One potential new target is hypoxanthine-guanine phosphoribosyltransferase (MtHGPRT), a key enzym

60 ated a cell line derived from a hypoxanthine-guanine phosphoribosyltransferase negative (HPRT-) HT108

61 and Arg(63), in contrast to the hypoxanthine-guanine phosphoribosyltransferases, which use two Mg2+ i

62 possess two purine salvage enzymes: xanthine-guanine phosphoribosyltransferase (XGPRT) and hypoxanthi