ライフサイエンスコーパス: guanine residue

1 on between the ligand's alkyl chloride and a guanine residue.

2 complementary bond to O6 of the alternative guanine residue.

3 at all mismatches except those containing a guanine residue.

4 stem loop recognition motif by exchange of a guanine residue.

5 bases 3' of a syn-DMBADE-modified adenine or guanine residue.

6 ovalently intercalated on the 5' face of the guanine residue.

7 whereas all 76 other complex isolates had a guanine residue.

8 ch are stabilized by the hydrogen bonding of guanine residues.

9 s consisting of a planar arrangement of four guanine residues.

10 derivatives as well as oxidized cytosine and guanine residues.

11 yl aminofluorene adducted- and cisplatinated-guanine residues.

12 ed by MMR by increasing mutations at runs of guanine residues.

13 Mutations of the critical guanine residues (-135/-136) decreased the formation of

14 as located by primer extension analysis to a guanine residue 8 bp 5' of the malA start codon.

15 eaks and in base excision repair of oxidized guanine residues (8-oxoguanine) by aiding the localizati

16 that include steroid-dependent protection of guanine residues -889 and -885 and hypersensitivity of a

17 ppery sequence of six adenine residues and a guanine residue (A6G) and a 3' secondary structure.

18 ded chlorambucil was shown to label a target guanine residue adjacent to its binding site in 80% effi

19 these, 63 and 36%, respectively, occurred at guanine residues along the cII gene.

20 aining a dynamic equilibrium of extrahelical guanine residues also suggested that the nickel complex

21 B and Sp1 were modified site-specifically at guanine residues and electrophoretic mobility shift assa

22 ide core sequence has eight highly conserved guanine residues and forms a G-quadruplex structure.

23 ates reactive oxygen species that can damage guanine residues and lead to the production of 8-oxoguan

24 The inability of SP to cut at guanine residues and the favoring of A-T-rich regions di

25 ng a simulated annealing protocol showed the guanine residues and the tether lay approximately in a p

26 ched when PdC is paired with a complementary guanine residue, and thus is greatly enhanced upon forma

27 No sequences containing just a single guanine residue are acceptable.

28 ite and established the importance of the 5'-guanine residue as critical for high affinity binding.

29 highly conserved sequence consisting of six guanine residues at the 3' end of the PPT (hereafter ref

30 n and interference showed that CcpA contacts guanine residues at the outer bounds of amyO with higher

31 short as 8 bases, and (iii) substitutions of guanine residues caused at an increased frequency by the

32 cytosine residues are fully paired with the guanine residues, each using two Hoogsteen hydrogen bond

33 idine enhancement that occurs selectively at guanine residues either in RNA or in DNA at low Mg2+ con

34 y)Cl]+ bind DNA covalently at the N7 site of guanine residues forming mono-dentate adducts.

35 cca americana), removes specific adenine and guanine residues from the highly conserved, alpha-sarcin

36 le-stranded regions and, to a lesser extent, guanine residues from wobble base-pairs in hairpin stems

37 ddition, we observe a single hypermethylated guanine residue (G128), located within the Rev high-affi

38 oss-link bridges the 2-amino position of two guanine residues, G4 and G22.

39 tion-mediated PCR delineated the position of guanine residues important to vimentin expression.

40 ue with the N(2)-amino group of the opposing guanine residue in 5'-CAp sequences to generate hemiamin

41 terminus of the downstream (D+) segment to a guanine residue in a purine-rich tract in pol (AAAAGAAGA

42 Spontaneous oxidation of guanine residues in DNA generates 8-oxoguanine (oxoG).

43 redominantly to the exocyclic amino group of guanine residues in DNA in vivo and in vitro.

44 To achieve platination of the guanine residues in duplex II the central linker remains

45 e major sites of oxidation being the central guanine residues in each telomeric repeat.

46 ple-stranded complex and usually occurred at guanine residues in the flanking double-stranded DNA.

47 Guanine residues in the genome are vulnerable to attack

48 The guanine residues in the loop stabilize the duplex as a r

49 udies suggest that the major groove edges of guanine residues in Watson-Crick G.C base-pairs could po

50 h a concomitant displacement of the modified guanine residue into the minor groove in the methylated

51 signal amplification: (1) a large amount of guanine residues introduced on the electrode surface thr

52 The two opposing guanine residues involved in the cross-link were identif

53 SJG-136 (NSC 694501) selectively cross-links guanine residues located on opposite strands of DNA, and

54 propenals can transfer oxopropenyl groups to guanine residues of DNA to yield pyrimodopurinone (M(1)G

55 ns of both the loop thymine residues and the guanine residues of the adjacent quartet.

56 as significantly reduced compared with other guanine residues of the flanking regions in both in vitr

57 ween the polyaromatic core of the ligand and guanine residues of the outer G-quartets.

58 of the cytosine residue flanking the target guanine residue on the 5'-side.

59 rom the reaction of a DNA abasic site with a guanine residue on the opposing strand of the double hel

60 n interstrand cross-link via reaction with a guanine residue on the opposing strand.

61 conjugates that would react with a specific guanine residue on the template strand of the HER-2/neu

62 , with protein-DNA contact points located on guanine residues on both DNA strands within and just adj

63 e results suggest that the 2-amino groups of guanine residues on both strands of the nucleic acid pla

64 , determined that the modifications occur at guanine residues on either strand separated by 3 bp.

65 ypass did occur, pol gamma misincorporated a guanine residue opposite the 3'-thymine of the dimer onl

66 er as well as two stimulus-specific enhanced guanine residues possibly due to alterations in chromati

67 interact with DNA (AZB016) or cleave DNA at guanine residues, presumably through alkylation of the N

68 Likewise, point mutations of the protected guanine residues profoundly attenuated the response to t

69 10-tetrahydrobenzo[a]pyrene (anti-BPDE) with guanine residues prompted us to study the efficiencies o

70 ethylation patterns surrounding the targeted guanine residues strongly affect their probability to be

71 n addition, nickel-dependent modification of guanine residues surrounding the three-helix junction of

72 sion site to produce a bulge and tipping the guanine residues; the two guanines and the tether attain

73 ion of the efficiency of oxidative damage at guanine residues through long-range charge transport was

74 Acrolein reacts with DNA at guanine residues to form the exocyclic adduct, 8-hydroxy

75 in the consensus binding sequence (CB) with guanine residues was evaluated both in vitro and in vivo

76 sites were primarily at or one base 3' to a guanine residue, which correlated well with the distribu

77 te bound the duplex and alkylated the target guanine residues with high efficiency.

78 ion with DNA results in DNA damage mainly at guanine residues, with products from thymine oxidation a

79 8-Oxoguanine is formed by the oxidation of guanine residues within DNA by reactive oxygen species,

80 vivo revealed methylation protection of all guanine residues within the d(GA)(n).d(TC)(n).

81 oint mutations were introduced into specific guanine residues within the G-quadruplex-forming region

82 al level by frameshift mutations in a run of guanine residues within the hpuA sequence encoding the m

83 observed that the overall reactivity of the guanine residues within this tract toward DMS was signif

84 tituting a guanine analogue, 6MI, for single guanine residues within UV1C extends the DNAzyme's activ