ライフサイエンスコーパス: guanosine

1 converted to inosines, biological mimics for guanosine.

2 ontrolled presence or absence of a single 5' guanosine.

3 ), which catalyzes N7 methylation of the cap guanosine.

4 hydrogen bonding and cation-coordination of guanosines.

5 Impaired nitric oxide (NO )-cyclic guanosine 3', 5'-monophosphate (cGMP) signaling has been

6 l class of peptidic hormones that signal via guanosine 3',5'-cyclic monophosphate (cGMP) and systemic

7 In functional assays, oxLDL abolished guanosine 3',5'-cyclic monophosphate (cGMP)-mediated sig

8 signaling mediated by the nitric oxide (NO)/guanosine 3',5'-cyclic monophosphate (cGMP)/protein kina

9 em has been designed to achieve detection of guanosine 3',5'-cyclic monophosphate (cyclic GMP) in buf

10 5 inhibitors prevent the breakdown of cyclic guanosine 3',5'-monophosphate (cGMP) and therefore may b

11 Compounds that inhibit STa-induced cyclic guanosine 3',5'-monophosphate (cGMP) production were sel

12 (GCs), which synthesize the messenger cyclic guanosine 3',5'-monophosphate, control several sensory f

13 Levels of the stringent response alarmone guanosine 3'-diphosphate 5'-diphosphate (ppGpp) rise aft

14 mitting templated DNA synthesis from the cap guanosine 3'-OH primer by E. coli DNA polymerase II (B f

15 he cellular concentration of stress alarmone guanosine-3', 5'-bis pyrophosphate (ppGpp) is increased.

16 uctures of apo form and GTP analog, GDP, and guanosine-3',5'-bisdiphosphate (ppGpp)-bound BipA.

17 to amino acid starvation is orchestrated by guanosine-3',5'-bisdiphosphate and the transcription fac

18 ogical tasks, i.e. the degradation of cyclic guanosine-3',5'-monophosphate at specifically tuned rate

19 Pharmacological studies using radiolabeled guanosine 5'-3-O-([(35)S]thio)triphosphate and [(3)H]ket

20 Myristoylated and guanosine 5'-3-O-(thio)triphosphate (GTPgammaS)-loaded A

21 ed agonist Emax) in signaling events such as guanosine 5'-3-O-(thio)triphosphate binding and beta-arr

22 In guanosine 5'-3-O-(thio)triphosphate binding and INS1 832

23 ing cell-free aGPCR/heterotrimeric G protein guanosine 5'-3-O-(thio)triphosphate binding reconstituti

24 hydrolyzes GTP and readily binds its analog guanosine 5'-3-O-(thio)triphosphate.

25 s in sarcolemmal membranes for the effect of guanosine 5'-[beta,gamma-imido]triphosphate (GMP-PNP) on

26 is toxin and to intracellular application of guanosine 5'-[beta-thio]diphosphate trilithium salt and

27 ell as its functional antagonist properties (guanosine 5'-[gamma-(35)S-thio]triphosphate [GTPgamma(35

28 Guanosine 5'-[gamma-(35)S]-triphosphate assays displayed

29 '-[beta-thio]diphosphate trilithium salt and guanosine 5'-[gamma-thio]triphosphate tetralithium salt.

30 ular docking resulted into identification of guanosine 5'-diphosphate (GDP) as a promising hepcidin-b

31 plexes between K-Ras or the G12X mutants and guanosine 5'-diphosphate (GDP) or GDPnP (a stable GTP an

32 , we observed that in solution, farnesylated guanosine 5'-diphosphate (GDP)-bound K-Ras4B is predomin

33 review, we discuss newly elucidated roles of guanosine 5'-diphosphate 3'-diphosphate (ppGpp) in trans

34 onsequently, drugs targeting the inactive or guanosine 5'-diphosphate-bound conformation are not expe

35 ility of G-quartet stacks formed by disodium guanosine 5'-monophosphate (Na25'-GMP).

36 The Leishmania guanosine 5'-monophosphate reductase (GMPR) and inosine

37 GPR139 activity was measured using guanosine 5'-O-(3-[(35)S]thio)-triphosphate binding, cal

38 ivity of CB1, as indicated by a reduction in guanosine 5'-O-(3-thio)triphosphate binding.

39 Indeed, guanosine 5'-O-(thiotriphosphate) and GPCR agonists only

40 ometry, we observed that, in the presence of guanosine 5'-O-(thiotriphosphate), purified MxA disassem

41 d by angiotensin II, phenylephrine, GTP, and guanosine 5'-O-[gamma-thio]triphosphate (GTPgammaS).

42 PDE with known concentrations of the active (guanosine 5'-Omicron-(gamma-thio)triphosphate (GTPgammaS

43 benzylidene)-hydrazide (Dynasore), a dynamin guanosine 5'-triphosphatase inhibitor, protected stromal

44 d by the isolation of 3',8-cyclo-7,8-dihydro-guanosine 5'-triphosphate (3',8-cH2GTP) as the product o

45 y redistribution and pinpoint why the TS for guanosine 5'-triphosphate (GTP) hydrolysis is higher in

46 is constructed by a complex rearrangement of guanosine 5'-triphosphate (GTP) into cyclic pyranopterin

47 e (SAM) enzyme involved in the conversion of guanosine 5'-triphosphate (GTP) into cyclic pyranopterin

48 s), proteins that catalyze the hydrolysis of guanosine 5'-triphosphate (GTP) to promote conformationa

49 nal snapshots of free sGC, NO-bound sGC, and guanosine-5'-[(alpha,beta)-methylene]triphosphate-bound

50 otofilaments, and FtsZ polymers assembled in guanosine-5'-[(alpha,beta)-methyleno]triphosphate are co

51 ), Sec23-Sec24, and blocked upon addition of guanosine-5'-[(beta,gamma)-imido]triphosphate, a poorly

52 M saturation binding, including studies with guanosine-5'-[(beta,gamma)-imido]triphosphate, suggests

53 hway is redundant and contains two routes to guanosine-5'-monophosphate (GMP) formation: conversion f

54 inone (H2Q), N-acetyl-tyrosine (N-Ac-Tyr) or guanosine-5'-monophosphate (GMP) was investigated at var

55 Guanosine-5'-monophosphate reductase (GMPR) catalyzes th

56 oring of adenosine-5'-triphosphate (ATP) and guanosine-5'-triphosphate (GTP) in MCF-7 breast cancer c

57 me that catalyzes a complex rearrangement of guanosine-5'-triphosphate (GTP) in the first step of mol

58 orrelation (P-value=0.017) between 8-hydroxy guanosine (8-OHG) and MUC4 in primary pancreatic tumors

59 e to produce inosine, which is recognized as guanosine, a process known as A-to-I RNA editing.

60 While all tested guanosine analogs stimulate the splitting activity of Hf

61 The effects of the guanosine analogue ribavirin during EBOV infections were

62 ctivated to synthesize a hyperphosphorylated guanosine analogue, (p)ppGpp, which acts as a pleiotropi

63 e energy surface of ribose pseudorotation in guanosine and 2'-deoxyguanosine.

64 Both an invariant guanosine and a Mg(2+) are directly coordinated to the n

65 A dinucleoside containing guanosine and cytidine at the end groups has been prepar

66 Recently we reported that YTHDC1 prefers guanosine and disfavors adenosine at the position preced

67 y require derivatization to induce gelation, guanosine and its corresponding nucleotides are well kno

68 molecular chaperone for gelation of water by guanosine and lithium borate.

69 8-Hydroxy-deoxy guanosine and malondialdehyde levels as markers of oxida

70 ss (nitrotyrosine, urinary 8-hydroxy-2-deoxy-guanosine) and inflammation (IL-1beta mRNA, F4/80 immuno

71 phate, inosine monophosphate, adenosine, and guanosine) and kokumi (gamma-l-glutamyl-l-valine) taste-

72 ulation of inosine, 2'-deoxy-inosine (dIno), guanosine, and 2'-deoxy-guanosine (dGuo) in all cells, e

73 Inosine, dIno, guanosine, and dGuo were tested by using tandem mass spe

74 n, with a strong preference for cytidine and guanosine, and identified hotspots of ribonucleotide inc

75 periments demonstrated strong preference for guanosine at nt 22 of miR-122.

76 IV-1) proviral DNA contains three sequential guanosines at the U3-R boundary that have been proposed

77 ndicate that the PRNTase domain has a unique guanosine-binding mode different from that of eukaryotic

78 the M(+) cation helps stabilize the anionic guanosine-borate (GB) diesters, as well as the G4-quarte

79 The guanosine-borate (GB) hydrogel, which was characterized

80 hat ThT increases the stiffness of the Li(+) guanosine-borate (GB) hydrogel.

81 ulating levels of bis-(3',5')-cyclic-dimeric-guanosine (c-di-GMP), a second messenger that stimulates

82 luding small RNA, RNA, degradome or 7-methyl guanosine cap analysis of gene expression (CAGE), chroma

83 Eukaryotic mRNAs possess a methylated 5'-guanosine cap that is required for RNA stability, effici

84 mRNA from the poly(A) region to the 7-methyl guanosine cap.

85 hat viral RNAs containing a single 5' capped guanosine ((Cap)1G) are specifically selected for packag

86 nscripts that begin with two or three capped guanosines ((Cap)2G or (Cap)3G) are enriched on polysome

87 with the adenosine adjacent to the cytidine-guanosine (CG) dinucleotide motif led to a significant l

88 We used a photocaged guanosine derivative in an RNA oligonucleotide to tempor

89 eoxy-inosine (dIno), guanosine, and 2'-deoxy-guanosine (dGuo) in all cells, especially lymphocytes.

90 d, to a lesser degree, unmethylated cytosine-guanosine dinucleotides (CpGs), yet does not distinguish

91 ing pathway between the alpha5 helix and the guanosine diphosphate (GDP) binding pocket remains elusi

92 Bud3 catalyzes the release of guanosine diphosphate (GDP) from Cdc42 and elevates intr

93 BACKGROUND & AIMS: De novo synthesis of guanosine diphosphate (GDP)-fucose, a substrate for fuco

94 De novo synthesis of guanosine diphosphate (GDP)-fucose, a substrate for fuco

95 es with the enzyme fucosyltransferase-VI and guanosine diphosphate fucose to enhance the interaction

96 blasts displayed reductions in PMM activity, guanosine diphosphate mannose, lipid-linked oligosacchar

97 activating Ras into inactive Ras is bound to guanosine diphosphate, inactivating Ras.

98 e sequestered by long-range base pairing and guanosines essential for both packaging and high-affinit

99 e Rab5 promotes recruitment of the Ccz1-Mon1 guanosine exchange complex to endosomes to activate Rab7

100 e-activating protein RanGAP1 and the nuclear guanosine exchange factor (GEF) RCC1.

101 cilitating nucleotide exchange mediated by a guanosine exchange factor.

102 DNA structures containing unpaired guanosines flanking short (12- to 20-bp) dsDNA (Y-form D

103 We find that guanosine (G 1), when combined with 0.5 equiv of potassi

104 ated by Dim1 near the decoding site, and one guanosine (G1575) is N(7)-methylated by Bud23-Trm112 at

105 e of a pre-catalytic state of this RNA shows guanosine G40 and adenosine A32 close to the G53-U54 cle

106 nucleobases adenine, thymine, cytosine, and guanosine has been performed.

107 Inosine (IC50 = 3.7 microM) and guanosine (IC50 = 21.3 microM) had the highest affinitie

108 rred backbone cleavage next to adenosine and guanosine in CAD of (M+nH)(n+) and (M-nH)(n-) ions, resp

109 by the nucleobases of conserved uridine and guanosine in helix P4 of the RNA subunit (P RNA).

110 Collectively, our study identifies unpaired guanosines in Y-form DNA as a highly active, minimal cGA

111 Mean levels of guanosine, inosine, dGuo, and dIno were 4.4, 133.3, 3.6,

112 The RNA-TAG (transglycosylation at guanosine) is carried out by a bacterial (E. coli) tRNA

113 were predicted for riboflavin (vitamin B2), guanosine, leucine, methionine, and cysteine, among othe

114 improved malondialdehyde and 8-hydroxy-deoxy guanosine levels, and also deteriorated renal function.

115 NK1/2 and their role in controlling 7-methyl-guanosine (m(7)G) "cap"-independent translation at enter

116 c mRNAs generally possess a 5' end N7 methyl guanosine (m(7)G) cap that promotes their translation an

117 export and translation of specific methyl 7-guanosine (m(7)G)-capped mRNAs, respectively.

118 'ppp is capped by the addition of a 7-methyl guanosine (m7G) (Cap-0) and a 2'-O-methyl (2'-OMe) group

119 second messenger bis-(3'-5')-cyclic-dimeric-guanosine monophosphate (c-di-GMP) acts as an innate imm

120 ane protein whose bis-(3',5')-cyclic dimeric guanosine monophosphate (c-di-GMP) binding activity post

121 a higher level of bis(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) in cells respiring on

122 Bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) is a dynamic intracel

123 e bacterial second messenger cyclic di-3',5'-guanosine monophosphate (c-di-GMP) is a key regulator of

124 llular quadruplexes formed by cyclic dimeric guanosine monophosphate (c-di-GMP).

125 3B (PDE3B), and a membrane-permeable cyclic guanosine monophosphate (cGMP) analog on KATP channel ac

126 ) and significantly smaller levels of cyclic guanosine monophosphate (cGMP) and peroxisome proliferat

127 G protein-coupled receptors and cyclic guanosine monophosphate (cGMP) are implicated in the res

128 ic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) are now recognized as imp

129 Cyclic guanosine monophosphate (cGMP) is a second messenger mol

130 3',5'-Cyclic guanosine monophosphate (cGMP) is an important second me

131 The intracellular nucleotide cyclic guanosine monophosphate (cGMP) is found in many human or

132 Phosphodiesterase 5 (PDE5) hydrolyzes cyclic guanosine monophosphate (cGMP) leading to increased leve

133 The cyclic guanosine monophosphate (cGMP) specific phosphodiesteras

134 itric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in t

135 ownstream target of sildenafil in the cyclic guanosine monophosphate (cGMP)-activated protein kinase

136 el from Caenorhabditis elegans in the cyclic guanosine monophosphate (cGMP)-bound open state.

137 is the foraging gene, which encodes a cyclic guanosine monophosphate (cGMP)-dependent protein kinase

138 signalling paradigm, we show that the cyclic guanosine monophosphate (cGMP)-dependent protein kinase,

139 reas the response to ascr#3 relies on cyclic guanosine monophosphate (cGMP)-gated channels and activi

140 ic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP).

141 on of calcium influx into the cell by cyclic guanosine monophosphate (cGMP).

142 lyl-cyclase, GCY-8, which synthesizes cyclic guanosine monophosphate (cGMP).

143 In dilute 5'-guanosine monophosphate (GMP) solutions, G-quartets form

144 nce or absence of 7-nitroindazole and cyclic guanosine monophosphate accumulation was determined.

145 of cyclic adenosine monophosphate and cyclic guanosine monophosphate and is highly expressed in mediu

146 inorganic nitrate-nitrite, myocardial cyclic guanosine monophosphate content by neprilysin or phospho

147 ic oxide synthase 1 blockade inhibits cyclic guanosine monophosphate production; 3) pharmacological b

148 We further demonstrate that the gene for guanosine monophosphate reductase (GMPR) is a direct MIT

149 ssenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whethe

150 , Na2 [(HGMP)2 Mo5 O15 ]7 H2 O (1; where GMP=guanosine monophosphate), which spontaneously assembles

151 Guanosine monophosphate, among the nucleotides, has the

152 e show that M. tuberculosis activated cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)

153 The DNA sensor cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)

154 or of interferon genes (STING), 2'3'- cyclic guanosine monophosphate-adenosine monophosphate (cGAMP),

155 With the STING ligand cyclic guanosine monophosphate-adenosine monophosphate (cGAMP),

156 V infection and mice lacking STING or cyclic guanosine monophosphate-adenosine monophosphate synthase

157 Cyclic guanosine monophosphate-adenosine monophosphate synthase

158 a pathway dependent on the DNA sensor cyclic guanosine monophosphate-adenosine monophosphate synthase

159 stiff because of low nitric oxide and cyclic guanosine monophosphate.

160 bacterial second messenger (3'-5')-cyclic-di-guanosine-monophosphate (CDG) is a promising mucosal adj

161 ieties implicate modification on an internal guanosine N-2, rather than a ribose hydroxyl.

162 t inhibition by IFIT1 is dependent upon a 5' guanosine nucleoside cap (which need not be N7 methylate

163 nvolving formation of the C4' radical of the guanosine nucleoside that is subsequently excised.

164 ults in excision of most atoms of a specific guanosine nucleoside.

165 mationally locked sugar modified uridine and guanosine nucleosides was achieved via Vorbruggen or Mit

166 The uridine and guanosine nucleosides were found to be inactive in the h

167 RL13b) is a small GTPase that functions as a guanosine nucleotide exchange factor (GEF) for ARL3-GDP.

168 In this issue, Fine et al. identify the guanosine nucleotide exchange factor GEF-H1 as critical

169 ugh the commonly used U6 promoter requires a guanosine nucleotide to initiate transcription, thus con

170 des containing the 2'-O-(o-nitrobenzyl)-3'-S-guanosine nucleotide were then constructed, characterize

171 Despite supplementation, depletion of guanosine nucleotides (p < 0.001 at 24 and 72 h; 5, 100,

172 ing interactions suggest that the additional guanosines of the 2G and 3G RNAs remodel the base of the

173 receptor 9 (TLR9) agonist cytidine-phosphate-guanosine oligodeoxynucleotide (CpG) to determine effect

174 synthetic TLR9 agonists, cytosine-phosphate-guanosine oligodeoxynucleotides (CpG-ODN), to investigat

175 Addition of exogenous guanosine or GTP restores the invasiveness of mtp53 knoc

176 hat is mediated by the signaling nucleotides guanosine penta- and tetraphosphate (ppGpp).

177 at is dependent on the UvrD helicase and the guanosine pentaphosphate (ppGpp) alarmone/stringent resp

178 plasts, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) [collectively named "(

179 The alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (pp

180 izing c-di-GMP to 5'-phosphoguanylyl-(3',5')-guanosine (pGpG), which is then hydrolyzed to two GMP mo

181 di-GMP to produce 5'-phosphoguanylyl-(3',5')-guanosine (pGpG).

182 re associated with the hypomodification of a guanosine residue at position 37 (G37) of mitochondrial

183 trictly pyrimidine specific, as interspersed Guanosine residues are well tolerated within PTBP1 bindi

184 tly directed the misinsertion of uridine and guanosine, respectively.

185 ine mutation of Asp63, which coordinates the guanosine ribose hydroxyls, impairs DNAppG de-capping.

186 Telomere DNA is guanosine rich and, as such, can form highly stable seco

187 Telomeres are guanosine-rich nucleic-acid chains that fold, in the pre

188 and discover unexpectedly that PGL-1 DD is a guanosine-specific, single-stranded endonuclease.

189 ely spaced runs of three or more consecutive guanosines strongly tend to fold into stable G-quadruple

190 Effects of MPA exposure and guanosine supplementation on nucleotide concentrations i

191 rong support for a model proposing (p)ppGpp (guanosine tetra and penta-phosphate) as the master regul

192 The stringent response alarmones guanosine tetra- (ppGpp) and pentaphosphate (pppGpp) con

193 In bacteria and plant chloroplasts, guanosine tetraphosphate (ppGpp) and guanosine pentaphos

194 The stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind

195 t has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was

196 decreased synthesis of the second messenger guanosine tetraphosphate and limited induction of string

197 It is coordinated by the nucleotides guanosine tetraphosphate and pentaphosphate [(p)ppGpp],

198 Intriguingly, the second messenger, guanosine-tetraphosphate (ppGpp), which is produced duri

199 on cleavage activity identified an invariant guanosine that contributes to catalysis.

200 leotides that appear to mediate catalysis: a guanosine that we propose deprotonates the 2'-hydroxyl o

201 The length polymorphism of guanosine thymidine dinucleotide repeats in the heme oxy

202 We analyzed the allelic frequencies of guanosine thymidine dinucleotide repeats in the heme oxy

203 In conclusion, a greater number of guanosine thymidine dinucleotide repeats in the heme oxy

204 repair, at the mRNA level, a disease-causing guanosine to adenosine (G > A) mutation in the mouse MeC

205 ent, that a tRNA anticodon modification from guanosine to queuosine has coevolved with these genomic

206 ters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongsid

207 eins are constitutively active because their guanosine triphosphatase (GTPase) activity is disabled.

208 LRRK2 has guanosine triphosphatase (GTPase) and kinase activities,

209 ot involve the exocyst complex, a common Ral guanosine triphosphatase (GTPase) effector.

210 The small guanosine triphosphatase (GTPase) Rab7 has been implicat

211 ein synthesis, elongation factor G (EF-G), a guanosine triphosphatase (GTPase), binds to the ribosoma

212 osphorylation, we identified the RAB35 small guanosine triphosphatase (GTPase)-a protein previously i

213 is a disease-associated RAS subfamily small guanosine triphosphatase (GTPase).

214 and dispersed at the lagging pole where the guanosine triphosphatase activating protein MglB disrupt

215 Both Rab18 guanosine triphosphatase activity and isoprenylation are

216 treadmilling predominantly determined by its guanosine triphosphatase activity.

217 We found that HIV-1 Nef and the guanosine triphosphatase Arf1 induced trimerization and

218 is issue, Rafiq et al. reveal that the small guanosine triphosphatase ARF1, a well-known orchestrator

219 Here, we examine the function of Rho guanosine triphosphatase CDC-42 in AJ formation and regu

220 e cortical PAR proteins (including the small guanosine triphosphatase CDC-42) have an active role in

221 ino acid positions (p.G488R, p.A495V) in the guanosine triphosphatase domain, each segregating with a

222 sion cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal function

223 Activation of the small guanosine triphosphatase H-Ras by the exchange factor So

224 le protein 42 (Cdc42Hs) is a small, Rho-type guanosine triphosphatase involved in multiple cellular p

225 An intrinsic guanosine triphosphatase mediates a contact between the

226 Proteolytic cleavage of the dynamin-like guanosine triphosphatase OPA1 in mitochondria is emergin

227 The small guanosine triphosphatase Rab13 functions in exocytic ves

228 PIX and decreasing the activity of the small guanosine triphosphatase Rac1 and Cdc42.

229 ly was mediated by chromosomes and the small guanosine triphosphatase Ran in a process requiring ~16

230 show that mouse embryos that lack the small guanosine triphosphatase RSG1 die at embryonic day 12.5,

231 -membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fi

232 on factor 4 (EF4/LepA) is a highly conserved guanosine triphosphatase translation factor.

233 downstream signaling to engage small GTPase (guanosine triphosphatase) activation and AMPAR synaptic

234 ves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region

235 ere, we show that dynamin1 (Dyn1), the large guanosine triphosphatase, is an interacting partner of I

236 ionally enhanced by signaling from the small guanosine triphosphatase, Rac1.

237 hat Epo1p binds simultaneously to the Cdc42p guanosine triphosphatase-activating protein Bem3p.

238 ng the genes small ARF GAP1 (SMAP1), an ARF6 guanosine triphosphatase-activating protein that functio

239 is by regulating the expression level of Ras guanosine triphosphatase-activating protein.

240 ional activity for p120RasGAP (RASA1), a Ras guanosine triphosphatase-activating protein.

241 te plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading

242 idues in switch region I of immunity-related guanosine triphosphatases (GTPases) (IRGs), a family of

243 membrane protein that interacts with the Rag guanosine triphosphatases (GTPases) and Ragulator in an

244 (mTORC1) is recruited to the lysosome by Rag guanosine triphosphatases (GTPases) and regulates anabol

245 phatidylinositol 4-kinases (PI4Ks) and small guanosine triphosphatases (GTPases) are essential for pr

246 Rab guanosine triphosphatases (GTPases) control cellular tra

247 Rho guanosine triphosphatases (GTPases) control the cytoskel

248 creasing the activity of the recycling small guanosine triphosphatases (GTPases) Rab4 or Rab11 was su

249 al cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate cell polari

250 Ras guanosine triphosphatases (GTPases) regulate signaling p

251 Nutrients signal via the Rag guanosine triphosphatases (GTPases) to promote the local

252 e an interferon (IFN)-inducible subfamily of guanosine triphosphatases (GTPases) with well-establishe

253 involving the Ragulator complex and the Rag guanosine triphosphatases (GTPases), causing release of

254 e group of proteins, the Rho family of small guanosine triphosphatases (GTPases), is critical for thi

255 Many of those factors are guanosine triphosphatases (GTPases), proteins that catal

256 ner thought to be dependent on the Rag small guanosine triphosphatases (GTPases), the Ragulator compl

257 These processes all involve Rho family small guanosine triphosphatases (GTPases), which are regulated

258 Amino acids signal to mTORC1 through the Rag guanosine triphosphatases (GTPases).

259 importance and activates mTORC1 via the Rag guanosine triphosphatases and their regulators GATOR1 an

260 However, constitutively active Rag guanosine triphosphatases prevented TFEB translocation d

261 The activation of Rho guanosine triphosphatases within the extending growth co

262 d into motility signaling proteins (kinases, guanosine triphosphatases, and guanine exchange factors)

263 Two Rab guanosine triphosphatases-activating proteins (GAPs) hav

264 pparatus and physically interacts with small guanosine triphosphatases.

265 Dynamin superfamily molecular motors use guanosine triphosphate (GTP) as a source of energy for m

266 actions and by accelerating reactions of the guanosine triphosphate (GTP) hydrolysis cycle.

267 tyrosine kinase (RTK) ligands increase RhoA-guanosine triphosphate (GTP) in untransformed and transf

268 from Cdc42 and elevates intracellular Cdc42-guanosine triphosphate (GTP) levels in cells with inacti

269 nd controls rat sarcoma viral oncogene (RAS)-guanosine triphosphate (GTP) levels.

270 Here, we find that the binding of guanosine triphosphate (GTP) to one subunit inhibits the

271 s), such as adenosine triphosphate (ATP) and guanosine triphosphate (GTP), are signaling and bioenerg

272 d the availability of ATP, which regenerates guanosine triphosphate (GTP), powers ribosomes, and prom

273 he authors demonstrate that TBSV co-opts the guanosine triphosphate (GTP)-bound active form of the en

274 ng podosome formation increased the level of guanosine triphosphate (GTP)-bound ARF1.

275 n is initiated by the interaction of active, guanosine triphosphate (GTP)-bound Ras-related protein 1

276 rnesyl-dependent, but neither palmitoyl- nor guanosine triphosphate (GTP)-dependent, fashion.

277 s sustained by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nu

278 hen Anillin is knocked down, active Rho (Rho-guanosine triphosphate [GTP]), F-actin, and myosin II ar

279 ll polarity in the context of elevated Cdc42-guanosine triphosphate activity, similar to nonmalignant

280 -binding family of proteins that bind to the guanosine triphosphate cap at growing microtubule plus e

281 otein synthesis via assembly of the 7-methyl-guanosine triphosphate cap-dependent translation complex

282 ATII increased vascular guanosine triphosphate cyclohydrolase I expression and b

283 nflammatory cell-dependent increase of iNOS, guanosine triphosphate cyclohydrolase I, tetrahydrobiopt

284 rahydrobiopterin (BH4) biosynthetic enzymes (guanosine triphosphate cyclohydrolase-1 and dihydrofolat

285 Type 2 nodes with protein Blt1p, guanosine triphosphate exchange factor Gef2p, and kinesi

286 we show that FtsY-SecY complex formation is guanosine triphosphate independent but requires a phosph

287 BB, which are associated with CDC42, a small guanosine triphosphate protein linked to T-cell activati

288 rotein synthesis via tRNA aminoacylation and guanosine triphosphate regeneration.

289 1 is capable of catalyzing the conversion of guanosine triphosphate to cGMP.

290 was performed using (35)S-GTPgammaS (GTP is guanosine triphosphate) in primate brains.

291 served large GTPases (enzymes that hydrolyze guanosine triphosphate) involved in endocytosis and vesi

292 gnaling by converting active Ras is bound to guanosine triphosphate, activating Ras into inactive Ras

293 oteins normally using adenosine triphosphate/guanosine triphosphate, probably explains the disease.

294 NRAS is a guanosine triphosphate-binding protein whose most well-c

295 ed spatially and MglA only binds MreB in the guanosine triphosphate-bound form, the motility complexe

296 ite inhibited eukaryotic initiation factor 2-guanosine triphosphate-initiator methionyl transfer RNA

297 cells have suggested a critical role of Rap1-guanosine triphosphate-interacting adaptor molecule (RIA

298 tophan, proline, phenylalanine, uridine, and guanosine was found.

299 cofactor for deoxyribozymes, various labeled guanosines were site-specifically attached to 2'-OH grou

300 killing by exogenous cytidine, adenosine, or guanosine, whereas wild-type cells are not.