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1 rease intracellular concentrations of cyclic guanosine monophosphate.
2 stiff because of low nitric oxide and cyclic guanosine monophosphate.
3 a bacterial riboswitch that binds cyclic-di-guanosine monophosphate.
4 he Watson-Crick complementary nucleotide, 5'-guanosine monophosphate (5'-GMP), was seen in the case o
5 methyl ester (L-NAME), 8-bromo-cyclic 3',5'-guanosine monophosphate (8-bromo-cGMP), and nitroglyceri
6 e monophosphate [8br-cAMP] and 8bromo cyclic guanosine monophosphate [8br-cGMP]) in rat liver preserv
7 omo-cyclic AMP (8BrcAMP), and 8-bromo-cyclic guanosine monophosphate (8BrcGMP) also inhibited the glu
8 of sGCalpha1 is independent of NO and cyclic guanosine monophosphate, a major mediator of the sGC enz
11 al and bradykinin-stimulated cellular cyclic guanosine monophosphate accumulation and L-citrulline co
12 nce or absence of 7-nitroindazole and cyclic guanosine monophosphate accumulation was determined.
13 mined in vitro in cardiac fibroblasts cyclic guanosine monophosphate-activating and antiproliferative
15 e show that M. tuberculosis activated cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)
16 we show that HIV infection activates cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)
17 proaches led to the identification of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)
18 or of interferon genes (STING), 2'3'- cyclic guanosine monophosphate-adenosine monophosphate (cGAMP),
20 interferons through the production of cyclic guanosine monophosphate-adenosine monophosphate (cyclic
21 malian cytosolic extracts synthesized cyclic guanosine monophosphate-adenosine monophosphate (cyclic
22 a pathway dependent on the DNA sensor cyclic guanosine monophosphate-adenosine monophosphate synthase
23 V infection and mice lacking STING or cyclic guanosine monophosphate-adenosine monophosphate synthase
27 owing mRNA degradation, releasing N-7 methyl guanosine monophosphate and 5'-diphosphate terminated ca
28 In addition, CD-NP in vitro activates cyclic guanosine monophosphate and inhibits cardiac fibroblast
29 of cyclic adenosine monophosphate and cyclic guanosine monophosphate and is highly expressed in mediu
31 admixture was calculated, and plasma cyclic guanosine monophosphate and sildenafil concentrations we
32 iated with elevation of intraplatelet cyclic guanosine monophosphate and was reversed by the nitric o
33 xide-dependent signaling (via sGC and cyclic guanosine monophosphate) and nitric oxide-independent si
34 of cyclic adenosine monophosphate and cyclic guanosine monophosphate, and, consequently, exhibit a ce
35 n vascular endothelial growth factor, cyclic guanosine monophosphate, angiogenesis, endogenous cell p
36 i indicates that NO signaling through cyclic guanosine monophosphate arose before the origin of multi
37 ieved using a reversible biogel formed by 5'-guanosine monophosphate as the run buffer in capillary e
38 e significantly increases cortical levels of guanosine monophosphate both in ischemic and nonischemic
39 second messenger bis-(3'-5')-cyclic-dimeric-guanosine monophosphate (c-di-GMP) acts as an innate imm
40 ane protein whose bis-(3',5')-cyclic dimeric guanosine monophosphate (c-di-GMP) binding activity post
41 eased intracellular levels of cyclic dimeric guanosine monophosphate (c-di-GMP) compared to that of a
42 ignaling molecule bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) controls important bi
43 second messenger bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) controls secretion, c
46 a higher level of bis(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) in cells respiring on
49 e bacterial second messenger cyclic di-3',5'-guanosine monophosphate (c-di-GMP) is a key regulator of
52 ly controls the intracellular cyclic dimeric guanosine monophosphate (c-di-GMP) level through a recep
54 second messenger bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) plays a vital role in
56 activity towards bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP), but does not show di
57 erial secondary messenger, cyclic di-(3',5')-guanosine monophosphate (c-di-GMP), represents a balance
58 f the prokaryotic second messenger cyclic di-guanosine monophosphate (c-di-GMP), yet the signaling me
59 second messenger--bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP)--that perceives and t
60 osphodiesterase whose substrate is cyclic di-guanosine monophosphate (c-di-GMP)-a bacterial second me
62 concentrations of cyclic 3',5'-adenosine and guanosine monophosphates (cAMP and cGMP, respectively) b
65 bacterial second messenger (3'-5')-cyclic-di-guanosine-monophosphate (CDG) is a promising mucosal adj
68 aBalpha accumulation; and b) a stable cyclic guanosine monophosphate (cGMP) analog (8-bromo-cGMP) to
69 3B (PDE3B), and a membrane-permeable cyclic guanosine monophosphate (cGMP) analog on KATP channel ac
70 onary circulation, the roles of cyclic 3'-5'-guanosine monophosphate (cGMP) and cGMP-phosphodiesteras
71 phosphodiesterase (PDE V) metabolizes cyclic guanosine monophosphate (cGMP) and is abundant in the ki
72 In healthy control subjects, urinary cyclic guanosine monophosphate (cGMP) and natriuresis increased
73 ) and significantly smaller levels of cyclic guanosine monophosphate (cGMP) and peroxisome proliferat
74 5 (PDE5) catalytic-site affinity for cyclic guanosine monophosphate (cGMP) and potency of inhibitors
75 se type 5 (PDE5) acts specifically on cyclic guanosine monophosphate (cGMP) and terminates cGMP-media
76 s study we tested the hypothesis that cyclic guanosine monophosphate (cGMP) and the dependent protein
77 c guanosine monophosphate (RpcGMP), a cyclic guanosine monophosphate (cGMP) antagonist, attenuated th
79 ic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) are now recognized as imp
80 d evidence that nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) are signaling intermediat
82 ic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) as well as calcium and pH
84 ry vasodilation through activation of cyclic guanosine monophosphate (cGMP) by way of particulate gua
86 NO production, as estimated by aortic cyclic guanosine monophosphate (cGMP) concentration and endothe
87 and serum nitrite/ nitrate and atrial cyclic guanosine monophosphate (cGMP) concentrations were assay
89 ic oxide synthase (NOS) activity, and cyclic guanosine monophosphate (cGMP) content were also assesse
91 pothesized that nitric oxide promotes cyclic guanosine monophosphate (cGMP) formation, which, in turn
92 stimulates production and release of cyclic guanosine monophosphate (cGMP) from intestinal epithelia
94 ciated with a significant decrease in cyclic guanosine monophosphate (cGMP) generation after S-nitros
95 by increases in intracellular cyclic 3', 5'-guanosine monophosphate (cGMP) in a small network of 50
96 tion of NO, as estimated by measuring cyclic guanosine monophosphate (cGMP) in aortic tissue in two m
97 e (BNP) on cellular proliferation and cyclic guanosine monophosphate (cGMP) in human aortic vascular
98 2A)) receptors increase production of cyclic guanosine monophosphate (cGMP) in slices of rat frontal
99 lices obtained from endotoxemic mice, cyclic guanosine monophosphate (cGMP) increased significantly a
100 trite and nitrate accumulation and by cyclic guanosine monophosphate (cGMP) increases in rat reporter
107 Phosphodiesterase 5 (PDE5) hydrolyzes cyclic guanosine monophosphate (cGMP) leading to increased leve
108 and 28 days (n = 3) and evaluated for cyclic guanosine monophosphate (cGMP) levels (7 days), number o
109 th a short half-life, increases brain cyclic guanosine monophosphate (cGMP) levels and improves neuro
110 nger RNA (mRNA), protein, nitrite and cyclic guanosine monophosphate (cGMP) levels in Kupffer cells.
112 minute reperfusion cycles, myocardial cyclic guanosine monophosphate (cGMP) levels increased signific
114 ith and without SNP did not affect EC cyclic guanosine monophosphate (cGMP) levels, and the cGMP anal
115 osphorylation and activity as well as cyclic guanosine monophosphate (cGMP) levels, with all of these
117 Elevated intracellular levels of cyclic guanosine monophosphate (cGMP) may induce apoptosis, and
118 attributable to hyporesponsiveness of cyclic guanosine monophosphate (cGMP) mediated vasorelaxation e
120 ic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) often mediate antagonisti
121 producing the intracellular messenger cyclic guanosine monophosphate (cGMP) on activation with nitric
122 es the kinase independently of the NO-cyclic guanosine monophosphate (cGMP) pathway and is coupled to
123 , the diatomic gas is critical to the cyclic guanosine monophosphate (cGMP) pathway as it functions a
124 ion of the atrial natriuretic peptide-cyclic guanosine monophosphate (cGMP) pathway in cardiac electr
125 A key component of the nitric oxide-cyclic guanosine monophosphate (cGMP) pathway in smooth muscle
126 ates a soluble guanylyl cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway in the behavioral
127 or tone and platelet activity via the cyclic guanosine monophosphate (cGMP) pathway, but whether coro
128 n of intracellular Ca2+ ([Ca2+]i) and cyclic guanosine monophosphate (cGMP) production (index of nitr
130 provide evidence for a novel role of cyclic guanosine monophosphate (cGMP) signaling in the regulati
131 ne monophosphate (cAMP) and augmented cyclic guanosine monophosphate (cGMP) signaling is characterist
135 t on and independent of modulation of cyclic guanosine monophosphate (cGMP) subsequent to activation
137 as increased 11-fold and the K(i) for cyclic guanosine monophosphate (cGMP) was 27-fold higher than P
139 tigated whether nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) were involved in memory c
140 xide (NO), catalyzes the formation of cyclic guanosine monophosphate (cGMP), an intracellular second
142 l methods to study the effects of NO, cyclic guanosine monophosphate (cGMP), and peroxynitrite on the
143 nctions through its second messenger, cyclic guanosine monophosphate (cGMP), and protein kinase G (PK
144 soluble guanosine cyclase to produce cyclic guanosine monophosphate (cGMP), and we observed that EPO
145 itric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in t
148 ated events, such as the induction of cyclic guanosine monophosphate (cGMP), NADPH diaphorase activit
149 diameter, and its upstream control by cyclic guanosine monophosphate (cGMP), nitrosative/oxidative st
150 hibitors and activators of sGC, 3',5'-cyclic guanosine monophosphate (cGMP), protein kinase G (PKG),
151 duces plexus neurons to produce cyclic 3',5' guanosine monophosphate (cGMP), suggesting the presence
152 in follicular somatic cells, produces cyclic guanosine monophosphate (cGMP), which maintains meiotic
153 t, VWF did not promote an increase in cyclic guanosine monophosphate (cGMP), while agents that elevat
154 ownstream target of sildenafil in the cyclic guanosine monophosphate (cGMP)-activated protein kinase
156 ds on NOS2 activity and the canonical cyclic guanosine monophosphate (cGMP)-cGMP-dependent protein ki
159 nts are phosphorylated transiently by cyclic guanosine monophosphate (cGMP)-dependent protein kinase
160 is the foraging gene, which encodes a cyclic guanosine monophosphate (cGMP)-dependent protein kinase
161 signalling paradigm, we show that the cyclic guanosine monophosphate (cGMP)-dependent protein kinase,
162 reas the response to ascr#3 relies on cyclic guanosine monophosphate (cGMP)-gated channels and activi
163 tions in genes encoding subunits of a cyclic guanosine monophosphate (cGMP)-gated ion channel (tax-4
164 ndothelium-dependent and -independent cyclic guanosine monophosphate (cGMP)-mediated vasodilation in
165 a depolarizing conductance carried by cyclic guanosine monophosphate (cGMP)-sensitive cyclic nucleoti
166 ukocyte Mac-1-integrin activation and cyclic guanosine monophosphate (cGMP)-signaling, leading to red
178 ferative effect is mediated via an NO/cyclic guanosine monophosphate (cGMP)/cGMP-dependent protein ki
180 ble guanylyl cyclase (which generates cyclic guanosine monophosphate, cGMP) was the first identified
181 By using immunohistochemistry against cyclic guanosine monophosphate, cochlear sGC activity was local
182 inorganic nitrate-nitrite, myocardial cyclic guanosine monophosphate content by neprilysin or phospho
183 reduces nitric oxide bioavailability, cyclic guanosine monophosphate content, and protein kinase G (P
185 -cGMP) and N(2),2'-o-dibutyryl 3', 5'-cyclic guanosine monophosphate (dB-cGMP), and of the selective
186 endogenous peptide ligands initiates cyclic guanosine monophosphate-dependent (cGMP) salt and water
187 cycle progression, which include both cyclic guanosine monophosphate-dependent and -independent pathw
188 teins involved in the mating process, cyclic guanosine monophosphate-dependent kinase, and the cation
189 vessels from endotoxemic animals in a cyclic guanosine monophosphate-dependent manner, suggesting tha
191 either guanylyl cyclase A receptor or cyclic guanosine monophosphate-dependent protein kinase in cult
192 lar signal-related kinase pathway via cyclic guanosine monophosphate-dependent protein kinase signali
194 sis associated with increased urinary cyclic guanosine monophosphate excretion (UcGMPV), glomerular f
195 the formation of 3', 5'-cyclic adenosine or guanosine monophosphate from the corresponding nucleosid
196 ose media was paralleled by decreased cyclic guanosine monophosphate generation; however, there was n
197 nhibition of 3'-->5' exonuclease activity by guanosine monophosphate (GMP) abolished the ability of p
202 genetic approach in zebrafish, we found that guanosine monophosphate (GMP) synthetase mutant larvae d
203 catalyze the breakdown of cAMP and/or cyclic guanosine monophosphate (GMP) to their inactive form.
205 petitive substrate for ecto-5'-nucleotidase (guanosine monophosphate, GMP) did not affect basal VP re
207 Sildenafil is a potent inhibitor of cyclic guanosine monophosphate hydrolysis [corrected] in the co
208 Type 5 is the main factor regulating cyclic guanosine monophosphate hydrolysis and downstream signal
211 a greater elevation of intracellular cyclic guanosine monophosphate levels compared with nitric oxid
212 ricles from Cav-3 OE mice had greater cyclic guanosine monophosphate levels, less nuclear factor of a
215 thesis can be stimulated by the inclusion of guanosine monophosphate or specific oligoribonucleotides
216 NO-stimulated platelet generation of cyclic guanosine monophosphate (p < 0.02) but not with changes
218 zed ex vivo by augmentation of the NO-cyclic guanosine monophosphate pathway without normalization of
219 Mechanisms of action of nitric oxide/cyclic guanosine monophosphate/PDE5 pathway in the treatment of
220 llele of the gamma subunit of retinal cyclic guanosine monophosphate phosphodiesterase (PDE gamma) su
222 site mutation in intron 2 of the rod cyclic guanosine monophosphate-phosphodiesterase (cGMP) beta-su
223 ceptor-specific expression of the rod cyclic guanosine monophosphate-phosphodiesterase beta-subunit (
225 of Mg2+ concentration and the 2' OH group of guanosine monophosphate, prG, substrate on various steps
226 RO-25-6760, increased NPR-A-dependent cyclic guanosine monophosphate production and NPR-A gene expres
227 in reporter cells resulted in higher cyclic guanosine monophosphate production compared with the wil
228 lable BNP assays and cell activity by cyclic guanosine monophosphate production in vascular cells.
229 ic oxide synthase 1 blockade inhibits cyclic guanosine monophosphate production; 3) pharmacological b
230 x pathways that involve nitric oxide, cyclic guanosine monophosphate, protein kinase G, extracellular
233 We further demonstrate that the gene for guanosine monophosphate reductase (GMPR) is a direct MIT
234 f At IMPDH conforms to the IMP dehydrogenase/guanosine monophosphate reductase motif and contains an
235 as the mRNA levels of uncoupling protein 1, guanosine monophosphate reductase, and peroxisome prolif
236 xide synthase inhibitor, and Rp-8 CPT-cyclic guanosine monophosphate (RpcGMP), a cyclic guanosine mon
237 -targeted regulation of cardiomyocyte cyclic guanosine monophosphate-selective phosphodiesterase type
238 neurons, which utilize diverse cyclic 3',5'-guanosine monophosphate signaling pathways and could ser
240 bosyl pyrophosphate (PRPP) amidotransferase, guanosine monophosphate synthetase (GMPS) will not utili
242 te cyclase and a higher production of cyclic guanosine monophosphate that together may help explain s
243 ssenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whethe
246 , Na2 [(HGMP)2 Mo5 O15 ]7 H2 O (1; where GMP=guanosine monophosphate), which spontaneously assembles
247 ide-dependent excretion of sodium and cyclic guanosine monophosphate without affecting mean arterial
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