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1 ntestinal epithelia and are regulated by Rho guanosine triphosphatase.
2 ic factors were shown to be activated by Ran guanosine triphosphatase.
3 pparatus and physically interacts with small guanosine triphosphatases.
4 that it requires activity of one or more Rho guanosine triphosphatases.
5 keletal changes induced by the Rho family of guanosine triphosphatases.
6 where aPKC is activated by Rho family small guanosine triphosphatases.
7 we show that the Insert B domain of the Dnm1 guanosine triphosphatase (a DRP) contains a novel motif
9 d to and phosphorylated spine-associated Rap guanosine triphosphatase activating protein (SPAR), a po
10 and dispersed at the lagging pole where the guanosine triphosphatase activating protein MglB disrupt
11 ere evidence that neurofibromin, via its Ras guanosine triphosphatase -activating activity, controls
12 the MKlp1-CYK4 centralspindlin complex is a guanosine triphosphatase-activating protein (GAP) for Ra
16 me 2q31 that encodes alpha2-chimaerin, a Rac guanosine triphosphatase-activating protein (RacGAP) sig
17 and Plk3 interact with spine-associated Rap guanosine triphosphatase-activating protein (SPAR), a re
19 ucleotide-exchange factor ECT-2, and the Rho guanosine triphosphatase-activating protein CYK-4 modula
22 ng the genes small ARF GAP1 (SMAP1), an ARF6 guanosine triphosphatase-activating protein that functio
24 ppressor protein functions as a Ras-specific guanosine triphosphatase-activating protein, but the ide
28 human Tre-2/Bub2/Cdc16 domain-containing Rab guanosine triphosphatase-activating proteins (GAPs) and
31 downstream signaling to engage small GTPase (guanosine triphosphatase) activation and AMPAR synaptic
32 ion that is altered by inhibition of dynamin guanosine triphosphatase activity and is temporally dist
35 ling (RGS) proteins accelerate the intrinsic guanosine triphosphatase activity of heterotrimeric G-pr
36 ulin and it inhibited the colchicine-induced guanosine triphosphatase activity of tubulin, indicating
37 ing of the mutant ftsZ84, which has 1/10 the guanosine triphosphatase activity of wild-type FtsZ in v
38 merization, suppression of PDGF-induced Rac1 guanosine triphosphatase activity, and Akt and extracell
40 e kidney (MDCK) cells and identified the rho-guanosine triphosphatase adaptor and scaffolding protein
41 e proteins, inhibition of filamentous septin guanosine triphosphatases alleviates constriction defect
42 many membrane proteins, including the Ypt7p guanosine triphosphatase and a "SNARE complex" with Vam3
44 s the only known exchange factor for the Ran guanosine triphosphatase and performs essential roles in
45 t it was soluble and stable, did not bind to guanosine triphosphatases and bound more tightly to the
46 ormation requires the function of Rho family guanosine triphosphatases and reorganization of the acti
47 ell adhesion molecules that activate RAS/RHO guanosine triphosphatases and their effector mitogen-act
48 importance and activates mTORC1 via the Rag guanosine triphosphatases and their regulators GATOR1 an
49 gulate protein levels of MIG-2, a Rho family guanosine triphosphatase, and/or down-regulate INA-1, an
50 d into motility signaling proteins (kinases, guanosine triphosphatases, and guanine exchange factors)
51 ons in members of the RAS subfamily of small guanosine triphosphatases are found in > 30% of all huma
54 is issue, Rafiq et al. reveal that the small guanosine triphosphatase ARF1, a well-known orchestrator
55 phosphatase-activating protein for the small guanosine triphosphatase Arf1, and gcs1 mutants displaye
56 d Kinesin-6 (which carries activators of Rho guanosine triphosphatase) at the cell cortex using total
60 gine off switch by sensing mitochondrial Rho guanosine triphosphatase-Ca(2+) and as a brake by anchor
63 e cortical PAR proteins (including the small guanosine triphosphatase CDC-42) have an active role in
65 report a positive feedback loop between the guanosine triphosphatase Cdc42, a central determinant in
67 ves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region
72 a heterodimer composed of a conserved 54-kDa guanosine triphosphatase (cpSRP54) and a unique 43-kDa s
73 aintain a basal state of activation of small guanosine triphosphatases critical for normal T cell mot
74 uitment to the TASCC was amino acid- and Rag guanosine triphosphatase-dependent, and disruption of mT
75 uitment and assembly of some dynamin-related guanosine triphosphatases depends on adaptor proteins re
76 ino acid positions (p.G488R, p.A495V) in the guanosine triphosphatase domain, each segregating with a
77 pression of a dominant-active Drosophila Rho guanosine triphosphatase, Drac1, rescued photoreceptor m
79 is paper, we provide evidence that the large guanosine triphosphatase dynamin2 and its partner, endot
80 ociation factor Tif6 by the translocase-like guanosine triphosphatase Efl1 is a critical late maturat
81 sion cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal function
82 mber of a newly emerging 47-kilodalton (p47) guanosine triphosphatase family, LRG-47, that acts indep
83 s well as adherens junction proteins and Rho guanosine triphosphatase from the cell periphery to the
84 eractions of the ancient outer transmembrane guanosine triphosphatase, Fzo1, were required to promote
85 de exchange factor (GEF) for Tem1, the small guanosine triphosphatase governing activity of the Sacch
88 des Rop (RHO-like small G protein of plants) guanosine triphosphatase (GTPase) activating protein 4 (
89 ors (GEFs) and by RGS proteins, which act as guanosine triphosphatase (GTPase) activating proteins (G
91 action of SRP and SR, which stimulates their guanosine triphosphatase (GTPase) activities, leading to
92 s reveal the critical link between intrinsic guanosine triphosphatase (GTPase) activity and downstrea
93 ide-binding proteins (G proteins) that lacks guanosine triphosphatase (GTPase) activity in NIH-3T3 ce
94 eins are constitutively active because their guanosine triphosphatase (GTPase) activity is disabled.
95 gnaling (RGS) family stimulate the intrinsic guanosine triphosphatase (GTPase) activity of the alpha
96 Several members of this group stimulate the guanosine triphosphatase (GTPase) activity of various G
100 ich repeat kinase 2 (LRRK2) protein has both guanosine triphosphatase (GTPase) and kinase activities,
103 with Bnip-2, a protein that binds the small guanosine triphosphatase (GTPase) Cdc42 and a negative r
109 mal subunit rotation and is catalyzed by the guanosine triphosphatase (GTPase) elongation factor G (E
111 in RAB23, which encodes a member of the RAB guanosine triphosphatase (GTPase) family of vesicle tran
112 and constitutively active member of the Rho guanosine triphosphatase (GTPase) family, has been impli
114 of mTORC1 by amino acids is mediated by Rag guanosine triphosphatase (GTPase) heterodimers on the ly
115 w that TIP47 also bound directly to the Rab9 guanosine triphosphatase (GTPase) in its active, GTP-bou
116 ecause activation of Rap1, an abundant small guanosine triphosphatase (GTPase) in platelets, contribu
117 uring cotranslational protein targeting, two guanosine triphosphatase (GTPase) in the signal recognit
118 Here, we investigated whether Rap1, a small guanosine triphosphatase (GTPase) known to promote integ
124 hibits eotaxin-induced activation of the Rho-guanosine triphosphatase (GTPase) Rac, and Rac2-deficien
125 abrogated PDGF-mediated activation of small guanosine triphosphatase (GTPase) Rac1, a member of the
127 croinjection studies revealed a role for the guanosine triphosphatase (GTPase) Ran in NES-mediated ex
128 rt that is dependent on the ras-like nuclear guanosine triphosphatase (GTPase) Ran-TC4 and its associ
130 ayed but not early ERK activation, the small guanosine triphosphatase (GTPase) Rap1 was considered as
132 activation bioprobe), we revealed that Cdc42 guanosine triphosphatase (GTPase) remains inactive withi
133 on of an activated form of Cdc42, a Rho-type guanosine triphosphatase (GTPase) required for cell pola
134 lular factors to activation of the monomeric guanosine triphosphatase (GTPase) Rho control cytoskelet
136 In yeast and animal cytokinesis, the small guanosine triphosphatase (GTPase) Rho1/RhoA has an estab
139 y as part of a 43-member IFN-gamma-inducible guanosine triphosphatase (GTPase) superfamily in mouse a
141 e we show that transcripts for RhoA, a small guanosine triphosphatase (GTPase) that regulates the act
143 kinase G (PKG), protein kinase A (PKA), Rho guanosine triphosphatase (GTPase), and MLC phosphatase w
144 ein synthesis, elongation factor G (EF-G), a guanosine triphosphatase (GTPase), binds to the ribosoma
145 ivity is regulated by Rheb, a Ras-like small guanosine triphosphatase (GTPase), in response to growth
147 udy was to investigate the role of the small guanosine triphosphatase (GTPase), Rho, in the corneal e
148 osphorylation, we identified the RAB35 small guanosine triphosphatase (GTPase)-a protein previously i
149 by more than 90 percent its response to the guanosine triphosphatase (GTPase)-accelerating activity
151 sequence(s) of regulation of Ras activity by guanosine triphosphatase (GTPase)-activating proteins (G
152 ic cells involves membrane-localized and Rac guanosine triphosphatase (GTPase)-regulated reduced nico
155 te plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading
156 chromosome [SRPX], and retinitis pigmentosa guanosine triphosphatase [GTPase] regulator [RPGR]) are
157 ownstream target of Rho (a Ras-related small guanosine triphosphatase [GTPase]), is associated with l
158 idues in switch region I of immunity-related guanosine triphosphatases (GTPases) (IRGs), a family of
160 nucleotide exchange factors specific for Rho guanosine triphosphatases (GTPases) and invariably posse
161 ide exchange factors (GEFs) specific for Rho guanosine triphosphatases (GTPases) and invariably posse
162 membrane protein that interacts with the Rag guanosine triphosphatases (GTPases) and Ragulator in an
163 (mTORC1) is recruited to the lysosome by Rag guanosine triphosphatases (GTPases) and regulates anabol
164 phatidylinositol 4-kinases (PI4Ks) and small guanosine triphosphatases (GTPases) are essential for pr
168 ns, this process is mediated by dynamin-like guanosine triphosphatases (GTPases) called atlastins (AT
174 creasing the activity of the recycling small guanosine triphosphatases (GTPases) Rab4 or Rab11 was su
177 al cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate cell polari
179 st cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate polarized o
181 r-bundle morphogenesis whereby different Rho guanosine triphosphatases (GTPases) regulate the initiat
183 histicated mechanisms to modulate Rho family guanosine triphosphatases (GTPases) to mediate specific
184 uding amino acids, which act through the Rag guanosine triphosphatases (GTPases) to promote mTORC1 tr
187 e an interferon (IFN)-inducible subfamily of guanosine triphosphatases (GTPases) with well-establishe
188 involving the Ragulator complex and the Rag guanosine triphosphatases (GTPases), causing release of
190 e group of proteins, the Rho family of small guanosine triphosphatases (GTPases), is critical for thi
192 ner thought to be dependent on the Rag small guanosine triphosphatases (GTPases), the Ragulator compl
193 These processes all involve Rho family small guanosine triphosphatases (GTPases), which are regulated
195 y the activation of Ras homolog (Rho) family guanosine triphosphatases (GTPases), which regulate the
196 Rag proteins--a family of four related small guanosine triphosphatases (GTPases)--interact with mTORC
203 ular, we focus on the role of the Rho family guanosine triphosphatases in endothelial function and va
205 nin regulates the activity of the Rho family guanosine triphosphatases (including RhoA and Rac1) in a
206 proteolytic activation of PAK2 represents a guanosine triphosphatase-independent mechanism of PAK re
207 We found that the murine Irgm1 (LRG-47) guanosine triphosphatase induced autophagy and generated
208 le protein 42 (Cdc42Hs) is a small, Rho-type guanosine triphosphatase involved in multiple cellular p
212 a genetically encoded, photoactivatable Rac guanosine triphosphatase is sufficient to direct migrati
213 between phosphatidylinositol metabolites and guanosine triphosphatases is an important feature of the
215 ere, we show that dynamin1 (Dyn1), the large guanosine triphosphatase, is an interacting partner of I
222 e show that the mitochondrial outer membrane guanosine triphosphatase mitofusin (Mfn) 2 mediates Park
223 N-terminal domain (N-domain) or the central guanosine triphosphatase module (GTPase-domain) also con
226 Proteolytic cleavage of the dynamin-like guanosine triphosphatase OPA1 in mitochondria is emergin
229 IC4 and RIC3 pathways downstream of the ROP1 guanosine triphosphatase promoting actin assembly and di
237 ine nucleotide exchange factor for the small guanosine triphosphatase Rab8, to promote recruitment of
239 toward PDGF and also activation of the small guanosine triphosphatase Rac, which is essential for pro
241 es (Paks), downstream effectors of the small guanosine triphosphatases Rac and Cdc42, biochemically c
244 high degree of sequence similarity, the Rho guanosine triphosphatases Rac1 and Rac2 regulate distinc
246 nal display analysis, to show that the small guanosine triphosphatase Rac2 is expressed selectively i
247 ly was mediated by chromosomes and the small guanosine triphosphatase Ran in a process requiring ~16
250 were assembled around beads coated with the guanosine triphosphatase Ran, forming pseudo-nuclei that
251 repeat motifs and four binding sites for the guanosine triphosphatase Ran, is localized at the cytopl
255 diated activation of the integrin regulatory guanosine triphosphatase Rap1 via the recruitment and ac
257 uncaging to image the activity of the small guanosine triphosphatase Ras after NMDA receptor activat
258 mTOR is directly activated by the small guanosine triphosphatase Ras homolog enriched in brain (
260 inhibition of p75NTR signaling to the small guanosine triphosphatase Rho resulted in impaired HSC di
261 uanine exchange factor for the Rho family of guanosine triphosphatases (Rho GEF GTPases), as a protei
263 rotein kinase c-Src and stimulated the small guanosine triphosphatase RhoA, consequently inhibiting c
264 on factor FoxF directly upregulate the small guanosine triphosphatase RhoDF, which synergizes with Cd
266 show that mouse embryos that lack the small guanosine triphosphatase RSG1 die at embryonic day 12.5,
268 d by pleiotropic perturbations to Rho family guanosine triphosphatase signaling and myosin II activit
271 -membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fi
272 duced activation of Rap1A, a phox-associated guanosine triphosphatase that is regulated by cAMP.
274 ynamin-related protein 1 (Drp1), a cytosolic guanosine triphosphatase that polymerizes and constricts
275 protein kinases and the regulation of small guanosine triphosphatases that control cellular movement
276 s based on the activity of Rho and Rap small guanosine triphosphatases that control integrin activati
277 2 (SEPT2), a member of the septin family of guanosine triphosphatases that form a diffusion barrier
287 ture-sensitive allele of the shibire dynamin guanosine triphosphatase, which is required for synaptic
288 in the appressorium by means of four septin guanosine triphosphatases, which polymerize into a dynam
290 tioning at this same step, including the Rab guanosine triphosphatase Ypt1p, which associated with cy
291 like other organelles, requires a Rab-family guanosine triphosphatase (Ypt7p), a Rab effector and Sec
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