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1 ished against capsaicin-induced cough in the guinea pig.
2 yocytes and in isolated perfused hearts from guinea pig.
3 he induction of NAbs and T cell responses in guinea pigs.
4 ently HSV-1-infected mice and HSV-2-infected guinea pigs.
5 2)--to subdivide IC GABAergic cells in adult guinea pigs.
6 d Ag preparations were analyzed in immunized guinea pigs.
7 displayed marked attenuation in the lungs of guinea pigs.
8 of rodent models such as mice, rabbits, and guinea pigs.
9 d latent infection of dorsal root ganglia in guinea pigs.
10 ariant (SUDV-GA) that is uniformly lethal to guinea pigs.
11 ditory neurons of the inferior colliculus in guinea pigs.
12 viously seen in MARV-infected mice or inbred guinea pigs.
13 and attenuated phenotypes, respectively, in guinea pigs.
14 mapped to the outer domain of gp120 for some guinea pigs.
15 lication and transmission of bovine FLUDV in guinea pigs.
16 ary auditory cortex of urethane-anesthetized guinea pigs.
17 iber system model of tuberculosis, mice, and guinea pigs.
18 spiratory tract for intratracheally infected guinea pigs.
19 on cardiovascular parameters in anesthetized guinea pigs.
20 sGP does not affect pathogenicity of EBOV in guinea pigs.
21 enuated for replication in immunocompromised guinea pigs.
22 lungs but failed to persist in the lungs of guinea pigs.
23 the most potent NAb responses in vaccinated guinea pigs.
24 the viruses are lethal in mice, hamsters and guinea pigs.
25 d resulted in reduced viral loads in newborn guinea pigs.
26 infection of the lower respiratory tract of guinea pigs.
27 atients with COPD, healthy donors, mice, and guinea pigs.
28 grafts were performed on the calvaria of 36 guinea pigs.
29 induced sudden sensorineural hearing loss in guinea pigs.
30 rvallo termed Car(91) that was attenuated in guinea pigs.
31 n normal hearing, tinnitus, and non-tinnitus guinea pigs.
32 ous than the parental EA viruses in mice and guinea pigs.
33 e faithfully maintained upon transmission to guinea pigs.
35 BOV using a guinea pig model and recombinant guinea pig-adapted EBOV containing mutations at the edit
36 livers and spleens of guinea pigs in vivo, a guinea pig-adapted SUDV variant (SUDV-GA) uniformly leth
37 y-six outbred guinea pigs were infected with guinea pig-adapted ZEBOV and examined sequentially over
38 ell lines and pancreatic tissues of mice and guinea pigs, administration of ethanol reduced expressio
39 enic, we determined if Car(91) could protect guinea pigs against Guanarito virus (GTOV), a distantly
41 (EBOVDeltaVP30) protects immunized mice and guinea pigs against lethal challenge with rodent-adapted
42 Here we show TRPV4-induced activation of guinea pig airway-specific primary nodose ganglion cells
43 sA strain) increased sPLA2-IIA expression in guinea pig airways and was cleared more efficiently, com
44 paring pharmacokinetics from carbon-14 dosed guinea pigs analyzed by both CRDS and accelerator mass s
47 o urban air pollution leads to activation of guinea pig and human sensory nerves, which are responsib
48 e cleaned particles evoked depolarization of guinea pig and human vagus, and this was inhibited by a
49 characterized a new set of affinity-purified guinea pig and rabbit antibodies against RNA-binding pro
50 reatic cell lines as well as in tissues from guinea pigs and CFTR knockout mice after administration
51 this, we established a transmission model in guinea pigs and determined the mechanisms behind virus s
53 dy responses, we sequentially infected mice, guinea pigs and ferrets with divergent H1N1 or H3N2 subt
54 ers (sgp140) from a CD4-independent HIV-1 in guinea pigs and found that the sgp140 elicited ADCC-medi
55 ng immunity against Lassa virus challenge in guinea pigs and marmosets and virus-specific cell-mediat
57 rod increased motility in inflamed colons of guinea pigs and mice, whereas administration of GR113808
58 o nasal epithelium for intranasally infected guinea pigs and more widespread in the respiratory tract
60 estigate viral pathogenesis (mouse, hamster, guinea-pig and ferret) are naturally resistant to MERS-C
62 However, rodent models, including the mouse, guinea pig, and hamster, also exist for Ebola, Marburg,
64 c solutions caused depolarization of murine, guinea pig, and human vagus and firing of Adelta-fibers
65 ku strain) in C57BL/6J mice, C3HeB/FeJ mice, guinea pigs, and a mouse hollow-fiber model of infection
68 tains motility in healthy colons of mice and guinea pigs, and reduces inflammation in colons of mice
69 higher than class 1 to mice, rats, hamsters, guinea pigs, and/or rabbits in the examinees was 14.1% (
72 plicated in the nasal turbinate and lungs of guinea pigs at high titers and was also able to transmit
73 itive to either ITDs or ILDs in anesthetized guinea pig, before, during, and following recovery from
75 l entorhinal cortex of the in vitro isolated guinea pig brain during focal interictal and ictal disch
76 e and female mice and in the isolated female guinea pig brain preparation during perfusion with 4-AP.
78 oth tangential brain slices and the isolated guinea pig brain with the potassium channel blocker 4-am
81 y untreated exhaust ward air, and another 90 guinea pigs breathed only air from the same six-bed tube
84 uated for dissemination in immunocompromised guinea pigs but elicited ELISA and neutralizing response
85 brane fusion activity and viral virulence in guinea pigs, but it did not significantly affect cell en
86 region induce QTc prolongation in immunized guinea-pigs by targeting the HERG channel independently
89 data suggest that CO induces arrhythmias in guinea pig cardiac myocytes via the ONOO(-)-mediated inh
90 GC synaptic connections in the retina of the guinea pig (Cavia porcellus) by recording inhibitory cur
91 mic contractile indices in detergent-skinned guinea pig (Cavia porcellus) cardiac muscle fibers in th
92 ibed circumstantial evidence suggesting that guinea pigs (Cavia porcellus) lack CD59, at least on ery
97 f eliciting cross-neutralizing antibodies in guinea pigs, chimpanzees, and healthy human volunteers.
98 AAV.BDNF or AAV.Ntf3 was delivered to the guinea pig cochlea one week following deafening and ears
99 asured the travelling wave in regions of the guinea pig cochlea that respond to low frequencies (<2 k
100 -linear processing of sound performed by the guinea pig cochlea varies substantially between the coch
101 vivo to study the low-frequency part of the guinea pig cochlea, and found that sound stimulation cau
103 utively expressing GFP (H9 Cre-LoxP) in deaf guinea pig cochleae that were pre-conditioned to reduce
105 e bioassay, in vivo electrophysiology, and a guinea pig conscious cough model to investigate a role f
106 expression in sensory neurons supplying the guinea pig corneal epithelium, which have well-defined m
108 a novel vaccine strategy against congenital guinea pig cytomegalovirus (GPCMV) infection was develop
113 spite exhibiting no clinical signs, infected guinea pigs developed seroconversion and the viral antig
114 id (OA-NO2) on TRP channels were examined in guinea-pig dissociated dorsal root ganglia (DRG) neurons
117 phin gene inserts, AAV.BDNF and AAV.Ntf3, on guinea pig ears deafened systemically (kanamycin and fur
123 coprotein rabbit antiserum protected Hartley guinea pigs from lethal intraperitoneal infection with J
124 cross-reactive mAb that completely protected guinea pigs from the lethal challenge with heterologous
125 g (GP83), determined via a newly established guinea pig gamma interferon enzyme-linked immunosorbent
128 with statistical significance, groups of six guinea pigs (gps) were challenged intranasally (i.n.) or
130 ssible reassortant genotypes demonstrated in guinea pigs (Gt2, Gt3, Gt7, Gt10 and Gt13) were also the
131 rosomes (HLMs) or liver microsomes from male guinea pig, hamster, monkey, mouse, and rabbit or female
134 ) flux of recombinant P2X7 receptors of dog, guinea pig, human, monkey, mouse, rat, and zebrafish.
135 lectrically induced contractions in isolated guinea pig ileum via CB1 receptors (pEC50, 6.0 +/- 0.4).
136 r 5-HT3 receptor-induced contractions in the guinea pig ileum, which are down-regulated after chronic
139 herpes simplex virus 1 (HSV-1)-seropositive guinea pigs immunized and subsequently challenged intrav
141 10(7) PFU of Delta145 or parental virus into guinea pigs immunosuppressed with cyclophosphamide.
144 saging SUDV within the livers and spleens of guinea pigs in vivo, a guinea pig-adapted SUDV variant (
146 more, recordings of neural activity from the guinea pig inferior colliculus have shown that individua
147 lving mammalian intracochlear anatomy, fixed guinea pig inner ears were imaged as whole temporal bone
151 hea sections, show that mucosal infection of guinea pigs is an efficient model for Ebola transmission
152 inoid type 2 (CB2) receptors, as well as the guinea pig isolated ileum, using the full agonist CP5594
159 We applied this to experimentally infected guinea pig lung sections and were able to distinguish bo
160 mes in the persistence of M. tuberculosis in guinea pig lungs and underscore the applicability of thi
162 igh-frequency, subthreshold resonance in the guinea pig medial superior olive (MSO) was recently link
164 editing in the pathogenicity of EBOV using a guinea pig model and recombinant guinea pig-adapted EBOV
166 obust growth and contact transmission in the guinea pig model atypical of avian strains and indicativ
169 of conditioned neutrophils in a neutropenic guinea pig model increased bacterial clearance of Shigel
180 Analysis of virulence of the rJUNV in a guinea pig model of lethal infection that closely reprod
182 fiber system (HFS) model, murine model, and guinea pig model of tuberculosis as well as clinical stu
184 These findings suggest that the outbred guinea pig model recapitulates ZEBOV infection of primat
187 Based on the promising data generated in the guinea pig model, a formulation containing truncated gD-
190 /34 (H1N1) (PR8), is nontransmissible in the guinea pig model, making it a useful background in which
200 he transition to heart failure, we studied a guinea-pig model of angiotensin II infusion (400 ng kg(-
205 Strain-associated virulence was studied in guinea pig, monocyte-derived macrophage, and lysozyme re
206 age-clamp recordings were made from isolated guinea pig myocytes as well as from human embryonic kidn
207 mine the basis for CO-induced arrhythmias in guinea pig myocytes in which action potentials (APs) mor
208 ssion of these TS channels in cultured adult guinea pig myocytes, combined with a quantitative ventri
212 ents done on the altricial rat and precocial guinea pig neonate demonstrated that the effect of vasop
213 ation in auditory neurons of chinchillas and guinea pigs of both sexes, and show how heterogeneous tu
214 Motile responses were induced in isolated guinea pig OHCs by stimulation with an 8 V/cm external a
216 ation, we tracked reassortment in coinfected guinea pigs over time and given matched or discordant do
217 ra (Depo) treatment and from oophorectomized guinea pigs (OVX-GPs) treated with vehicle, estradiol (E
221 ted against EqCXCL16 or by pretreatment with guinea pig polyclonal antibody against EqCXCL16 protein
224 ere, we show that transgenic mice expressing guinea pig prion protein are fully susceptible to vCJD a
226 experimental challenge of immunocompromised guinea pigs, r129 induced significant weight loss, longe
227 the cervix of four placental mammals, mouse, guinea pig, rabbit and armadillo, and one marsupial, opo
229 KA phosphorylation sites conserved in human, guinea pig, rabbit, rat, and mouse alpha1C subunits.
230 different inducers; untreated male monkeys, guinea pigs, rabbits, and hamsters; and female dogs.
232 us was induced by low-dose streptozotocin in guinea pigs rendered glucose intolerant by first feeding
233 d secondary transmissions of BSE and vCJD in guinea pigs result in long incubation periods of approxi
235 from OFF delta retinal ganglion cells in the guinea pig retina and monitored synaptic currents that w
236 ion cells in a dense patch of salamander and guinea pig retinas while displaying a bar moving diffusi
241 armacokinetic and pharmacodynamic studies in guinea pigs showed that a single 5-min application of a
242 th the upper and lower respiratory tracts of guinea pigs, similarly to virus infection in its native
245 sed a greater number of coughs in CS-exposed guinea pigs than in control animals; similar increased r
246 We performed a genomic screen in pregnant guinea pigs that led to the identification of 201 lister
248 t of virus infections of cell culture and of guinea pigs that the SSP plays an essential role in medi
253 ocked cough and single C-fiber firing in the guinea pig to the transient receptor potential (TRP) V1
254 coinfection was achieved by exposing a naive guinea pig to two cagemates, one infected with wt and th
255 e ability of cells in the auditory system of guinea pigs to compare interaural level differences (ILD
256 delling with experiments in heart cells from guinea pigs to determine how cellular electrical activit
257 p140 protein in a prime-boost combination in guinea pigs to enhance envelope (Env)-specific humoral a
259 olerance and type 2 diabetes were induced in guinea pigs to model the emerging comorbidity of Mycobac
260 FLUDV was able to transmit from the infected guinea pigs to sentinel animals by means of contact and
261 ectivity profile, long duration of action on guinea pig trachea, and longer than salmeterol duration
262 cacy was evaluated by immunizing GPCMV-naive guinea pigs twice with either 10(5) or 10(6) PFU of Delt
263 ated the effect of theophylline on human and guinea pig vagal sensory nerve activity in vitro and on
264 ents in vivo and depolarization of human and guinea pig vagus in vitro, and inhibited calcium influx
265 aber-Rudy computationally based model of the guinea pig ventricular action potential, we simulated ef
267 e effects of GS-458967 on endogenous INaL in guinea pig ventricular myocytes demonstrate a robust con
268 ich it is used to develop models of isolated guinea pig ventricular myocytes that simulate the electr
272 FLUDV replicated in the respiratory tract of guinea pigs was similar to observations described previo
273 of LASV that is uniformly lethal in Hartley guinea pigs, we demonstrate that favipiravir, a broad-sp
281 eatures of disease in ZEBOV-infected outbred guinea pigs were largely consistent with disease in huma
286 and SEBOV-induced disease in outbred Hartley guinea pigs where we observed protection from effects of
287 of allergen-specific blocking IgG in outbred guinea pigs which had been immunized with recombinant bi
288 We assessed hearing recovery in LPS-applied guinea pigs, which were either left untreated or were sy
289 Here, we describe a study with isogenic guinea pigs, which would uniquely combine the advantages
290 bacteremia in mice and abortion in pregnant guinea pigs, while complementation of capsule expression
297 e tested the hypothesis that immunization of guinea-pigs with a peptide corresponding to the E-pore r
299 ection in its native host, demonstrates that guinea pigs would be a suitable model host to study the
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