ライフサイエンスコーパス: gustatory

1 lted in significant reorganization of mature gustatory afferent terminal fields in the nucleus of the

2 We investigated whether gustatory afferents express functional 5-HT3 receptors a

3 ying interactions, via transmitters, between gustatory and chemosensory afferents inside taste buds w

4 ters mainly project on a prominent secondary gustatory and general visceral nucleus (SGN/V) located i

5 Insect gustatory and odorant receptors (GRs and ORs) form a sup

6 hould be considered during the evaluation of gustatory and olfactory epileptic seizures.

7 The integration of gustatory and olfactory information is essential to the

8 role of insular cortex in the processing of gustatory and olfactory inputs, the exact location of ol

9 vivo functional imaging techniques to trace gustatory and olfactory pheromone circuits to their poin

10 construction of a "flavor" percept when both gustatory and olfactory stimuli are present.

11 (odor-only), or bimodal, responding to both gustatory and olfactory stimuli.

12 the development and early functioning of the gustatory and olfactory systems.

13 erts its potent reinforcing effects via both gustatory and post-ingestive pathways.

14 ucleus of the solitary tract (NST) processes gustatory and related somatosensory information rostrall

15 ctopic taste buds form independently of both gustatory and somatosensory innervation.

16 nalyses to reveal major distinctions between gustatory and somatosensory neurons and subclusters of g

17 hich, by anterograde labeling, correspond to gustatory and somatosensory neurons.

18 r integration centers for olfactory, visual, gustatory and tactile information.

19 yramine receptors are involved in modulating gustatory and tactile perception.

20 Ex4-induced hypophagia, as the PBN receives gustatory and visceral afferent relays and descending in

21 tional and affective states, but not primary gustatory and viscerosensory information, has direct acc

22 high-sugar food activates mesolimbic reward, gustatory, and oral somatosensory brain regions, contrib

23 tes positively with activity in attentional, gustatory, and reward regions when anticipating palatabl

24 The smallest subcluster expresses both gustatory- and mechanosensory-related genes, suggesting

25 th lean individuals show greater attention-, gustatory-, and reward-region responsivity to food cues

26 anterior insula that may include the primary gustatory area (area G) and other cortical taste-process

27 sociation of taste sensor outputs with human gustatory assessment, salt content, and bioactivity.

28 mice, tongue innervation was disrupted, and gustatory axons failed to reach their targets.

29 Gustatory axons from internal and external taste sensill

30 tax-4 genes, are essential for ASE-mediated gustatory behavior.

31 w- and high-fat meals affect homeostatic and gustatory brain areas differentially.

32 fat might be a modulator of homeostatic and gustatory brain regions and their interaction.

33 Main primary gustatory centers (facial and vagal lobes) received sens

34 The connectivity between diencephalic gustatory centers and the telencephalon was also investi

35 n the basis of food-predicting cues, whereas gustatory circuits are believed to be involved in the ev

36 essary for the normal maintenance of central gustatory circuits at adulthood and highlights a level o

37 little is known, however, about higher-order gustatory circuits in the highly tractable model for neu

38 the functional and structural development of gustatory circuits.

39 eural activity has a role in shaping central gustatory circuits.

40 g a taste association paradigm revealed that gustatory conditioning also requires the mushroom bodies

41 The present results showed that the gustatory connections of the adult zebrafish are rather

42 neuroimaging experiments have pointed to the gustatory cortex (GC) as one of the areas involved in me

43 signal revealed that neurons in the primary gustatory cortex (GC) can respond to anticipatory cues.

44 Primary gustatory cortex (GC) is connected (both mono- and polys

45 The gustatory cortex (GC) is widely regarded for its integra

46 es of indirect evidence suggest that primary gustatory cortex (GC) may be a part of a distributed for

47 Here, we provide evidence that gustatory cortex (GC) may be part of the forebrain circu

48 somatosensory, and olfactory stimuli in the gustatory cortex (GC) of alert rats before and after ass

49 g of taste has focused on either the primary gustatory cortex (GC) or the orbitofrontal cortex (OFC).

50 The primary gustatory cortex (GC) receives projections from the baso

51 Taste-related information reaches the gustatory cortex (GC) through two routes: a thalamic and

52 Gustatory cortex (GC), an assemblage of taste-responsive

53 n the brainstem and sends projections to the gustatory cortex (GC).

54 luences processing of sensory stimuli in the gustatory cortex (GC).

55 out the organization of taste information in gustatory cortex (GC).

56 irst, we demonstrate that ZIP infusions into gustatory cortex begin interfering with CTA memory 43-45

57 et and bitter are represented in the primary gustatory cortex by neurons organized in a spatial map,

58 Here we found that neurons in gustatory cortex can respond either exclusively to tasta

59 local microinjection of PKR inhibitor to the gustatory cortex enhanced both positive and negative for

60 The primary gustatory cortex has been proposed to integrate chemosen

61 tudies investigating taste coding within the gustatory cortex have reported highly segregated, taste-

62 (N=8), targeting the conventionally defined gustatory cortex in each hemisphere, and were implanted

63 findings do not rule out involvement of the gustatory cortex in palatability processing, they make e

64 ough multiple neural stations to the primary gustatory cortex in the brain.

65 alysis of multielectrode recordings from the gustatory cortex of alert rats revealed ongoing sequence

66 ulus information in LFPs and spikes from the gustatory cortex of awake rats subjected to tastants and

67 Altogether, our results show that the gustatory cortex represents cross-modal stimuli accordin

68 ste responses, and illustrate the ability of gustatory cortex to recapitulate complex behaviours in t

69 d that, on average, approximately 94% of the gustatory cortex was destroyed.

70 cally coupling microelectrode array to rat's gustatory cortex with brain-machine interface (BMI) tech

71 g and attention), frontal operculum (primary gustatory cortex) when anticipating palatable food, and

72 al taste reactivity behavior, lesions of the gustatory cortex, a region that has been suggested to be

73 stimulated neurons were found throughout the gustatory cortex, but a "hot spot" was observed in its a

74 Besides homeostatic processes, the gustatory cortex, including parts of the insular cortex,

75 the subregion approximating the dysgranular gustatory cortex.

76 synaptic properties of the BLA input to the gustatory cortex.

77 tern, recording the activity of ensembles of gustatory cortical single neurons as rats that normally

78 Together our data suggest that different gustatory cues can modulate the activities of distinct s

79 us relies mainly on contact chemosensory and gustatory cues.

80 Experimental gustatory curves have been fitted for four sugars (sucro

81 We conclude that gustatory detection of Ca(2+) represents an additional s

82 Understanding the mechanisms underlying oro-gustatory detection of dietary fat is critical for the p

83 MAPK pathways, in particular, ERK1/2, in the gustatory detection of fatty acids.

84 a heteromeric DEG/ENaC channel required for gustatory detection of female pheromones.

85 s of taste 2 receptor genes expressed in the gustatory end organs enable bony vertebrates (Euteleosto

86 d neurotrophic factor (BDNF) is expressed in gustatory epithelia and is required for gustatory neuron

87 ted that DEGs between gustatory (GE) and non-gustatory epithelium (NGE), and between GE and the under

88 ere significantly reduced by blockade of the gustatory epithelium, were unaffected by blockade of the

89 e the likely area of insular cortex given to gustatory function and to characterize taste responses w

90 local taste receptor gene expression in the gustatory ganglia and the brain.

91 f oral cavity demonstrated that DEGs between gustatory (GE) and non-gustatory epithelium (NGE), and b

92 The central connections of the gustatory/general visceral system of the adult zebrafish

93 ed different gene expression profiles in the gustatory (geniculate) ganglion.

94 ity, associated derealisation, olfactory and gustatory hallucinations, physical symptoms such as head

95 c) of rats may mediate opioid enhancement of gustatory hedonic impact or "liking".

96 We also note that the gustatory influence on lifespan does not necessarily dep

97 Here we tested the hypothesis that gustatory influence on olfactory processing occurs at th

98 Gustatory information can also reach another frontal reg

99 rvae employ a surprisingly different mode of gustatory information coding.

100 how the gustatory thalamus (VPMpc) processes gustatory information in behaving rats.

101 via serotonergic signaling during processing gustatory information in taste buds.

102 Animals use gustatory information to assess the suitability of poten

103 nerve (CT), one of three nerves that convey gustatory information to the nucleus of the solitary tra

104 ) is the part of the thalamus that processes gustatory information.

105 ch less is known on how VPMpc neurons encode gustatory information.

106 of general innervation and specifically the gustatory innervation was markedly increased in high BDN

107 for the dependence of taste cell renewal on gustatory innervation, neurotrophic support of taste bud

108 te buds is intimately dependent on an intact gustatory innervation, yet the molecular nature of this

109 to identify a neural circuit that integrates gustatory input and hunger state to modulate food ingest

110 amic causal modeling supports unidirectional gustatory input from basolateral amygdala (BLA) to hypot

111 In contrast, during hunger, gustatory inputs enter the hypothalamus and drive bidire

112 ence shows that the VPMpc receives ascending gustatory inputs from the parabrachial nucleus (PbN) in

113 ty is necessary for the normal maturation of gustatory inputs into the brain.

114 room bodies, revealing the essential role of gustatory inputs not only as rewards and punishments but

115 Numerous sensory structures (e.g., auditory, gustatory, lateral line, olfactory, and visual nuclei) a

116 pts several behaviors, such as olfactory and gustatory learning behavior and touch habituation.

117 fat-triggered sensations in the brain on the gustatory level, possibly by ingredients the body implic

118 Our results demonstrate a gustatory mechanism that mediates the detection and bloc

119 generalized damage to biological systems, no gustatory mechanism to prevent ingestion of such materia

120 e demonstrated that bilateral lesions of the gustatory (medial) zone of the parabrachial nucleus (PBN

121 s) perceive chemical stimuli of one specific gustatory modality associated with a stereotyped behavio

122 Gustatory mutants form networks that cannot be distingui

123 ent responses in a subset of sweet-sensitive gustatory nerve fibers but did not affect other types of

124 5-HT released from type III cells activates gustatory nerve fibers via 5-HT3 receptors, accounting f

125 ells (TCs) that relay quality information to gustatory nerve fibers.

126 These surprising results suggest that gustatory nerve terminal fields remain plastic well into

127 tor site which fires a minimal response at a gustatory nerve.

128 gehog (Hh) pathway inhibitor (HPI), and that gustatory nerves are a source of sonic hedgehog (Shh) fo

129 Remarkably, when lingual gustatory nerves are surgically rerouted to inappropriat

130 ed epithelial cells, which are innervated by gustatory nerves that transmit taste information to the

131 leased 5-HT activates 5-HT3 receptors on the gustatory nerves.

132 actions and taste coding.Characterization of gustatory neural pathways has suffered due to a lack of

133 tract (NTS), the first relay in the central gustatory neuraxis, a rich variety of sensory inputs gen

134 This study used sweet tastes to interrogate gustatory neurocircuitry involving the anterior insula a

135 drogen peroxide and oxygen, functions in the gustatory neuron ASER to mediate C. elegans pathogen avo

136 in a directionally asymmetric manner in the gustatory neuron pair ASE left (ASEL) and ASE right (ASE

137 h two other CNG subunits, TAX-2 and TAX-4, a gustatory neuron-specific heteromeric CNG channel comple

138 lp dissect the functional distinctions among gustatory neurons and address questions regarding target

139 ay strong aversive responses to LPS and that gustatory neurons expressing Gr66a bitter receptors medi

140 ults demonstrated that individual peripheral-gustatory neurons generate a unique and reliable firing

141 receives input from the vagal-responsive and gustatory neurons in the basal part of the ventral media

142 no was coexpressed with Gr66a in a subset of gustatory neurons in the terminal organ of third-instar

143 targeted expression of nope in the subset of gustatory neurons in which ppk25 functions.

144 The disruption of sano gene expression in gustatory neurons led to the specific loss of high-salt

145 tens lifespan, whereas a different subset of gustatory neurons lengthens it.

146 Many basic characteristics of gustatory neurons remain unknown, partly due to the abse

147 cific, nonredundant functions in a subset of gustatory neurons required for activation of male courts

148 d in gustatory epithelia and is required for gustatory neurons to locate and innervate their correct

149 and somatosensory neurons and subclusters of gustatory neurons with unique molecular and functional p

150 g the AWC olfactory neurons, the ASJ and ASK gustatory neurons, and the ASH and ADL nociceptors, resp

151 In Caenorhabditis elegans, a subset of gustatory neurons, as well as olfactory neurons, shorten

152 Among the gustatory neurons, three subclusters are present, each w

153 ed GLP-1 and its receptors were expressed in gustatory neurons.

154 of different combinations of bitter-sensing gustatory neurons.

155 te these effects, we silenced bitter-sensing gustatory neurons.

156 immunoreactivity) in subregions of hindbrain gustatory nuclei were restored if the posterior tongue,

157 The posterior thalamic nucleus, tertiary gustatory nucleus proper, and nucleus of the lateral rec

158 d fiber-rich region termed here the tertiary gustatory nucleus proper, but not to a nucleus formerly

159 d in other cyprinids, excepting the tertiary gustatory nucleus.

160 of taste quality information in the primary gustatory nucleus.

161 ormerly considered as the zebrafish tertiary gustatory nucleus.

162 Our data also show a spatial overlap between gustatory, olfactory, and oral somatosensory representat

163 tive states, and processing information from gustatory, olfactory, auditory, somatosensory, and nocic

164 a variety of sensory information, including gustatory, olfactory, somatosensory, visual, and auditor

165 is critical to early nutrition but is also a gustatory-olfactory aspect of early infant social behavi

166 no are required in the neurons of the larval gustatory organs for the detection of high-salt concentr

167 that flies detect bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved

168 (NTS; the first neural relay in the central gustatory pathway) in awake, freely licking rats.

169 neurotransmitter to activate afferent neural gustatory pathways.

170 er observations indicate that lesions of the gustatory PBN in rats may or may not eliminate salt appe

171 TAS2Rs such as TAS2R16 help define gustatory perception and dietary preferences that ultima

172 Finally, we show that gustatory perception is required for survival, specifica

173 bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.

174 We determined that gustatory perception of sweetness is both necessary and

175 se results demonstrate an important role for gustatory perception when environmental food availabilit

176 Gustatory pheromones are thought to activate P1 neurons

177 t it influences a learning behavior known as gustatory plasticity, in which it is functionally couple

178 The gustatory, primary auditory, primary visual, rostrolater

179 Olfactory and gustatory processes especially need to be adaptive and r

180 ur results provide a foundation for studying gustatory processing and its modulation by the internal

181 physicochemical parameters, colour, olfacto-gustatory profile, and volatile compounds were tested.

182 Here we report second-order sweet gustatory projection neurons (sGPNs) in the Drosophila b

183 The molecular genetic analysis of Gustatory receptor (Gr) genes and the characterization o

184 re coexpressed with bitter- or sugar-sensing Gustatory receptor (Gr) genes.

185 LITE-1, a seven-transmembrane gustatory receptor (GR) homolog, mediates UV-light-induc

186 cluding receptors of the odor receptor (Or), gustatory receptor (Gr), ionotropic receptor (IR), Pickp

187 ng is inhibited by the taste receptor Gr32a (Gustatory receptor 32a) and a neural circuit in which it

188 havior as well as many novel loci, including gustatory receptor 63a (Gr63a), which encodes a subunit

189 female sexual pheromones through a specific gustatory receptor expressed in a subset of foreleg neur

190 The gustatory receptor family members LITE-1 and GUR-3 are r

191 gradient does not require TRPA1; rather, the gustatory receptor GR28B(D) drives this behaviour throug

192 A recent study has found that a Drosophila gustatory receptor is required for thermotaxis.

193 nd Gr98b in Gr66a-expressing, bitter-sensing gustatory receptor neurons (GRNs) confers responsiveness

194 Here we identify sour gustatory receptor neurons (GRNs) in tarsal taste sensil

195 In adult Drosophila, gustatory receptor neurons (GRNs) perceive chemical stim

196 Flies use distinct types of gustatory receptor neurons (GRNs) to respond to differen

197 s, D-fructose and D-glucose stimulated sugar-gustatory receptor neurons (GRNs), whereas the deterrent

198 mechanisms-activation of a specific class of gustatory receptor neurons (GRNs), which suppresses feed

199 ds fatty acids are mediated by sweet sensing Gustatory Receptor Neurons (GRNs).

200 TPNs receive input from gustatory receptor neurons and respond selectively to sw

201 ques to deliver taste stimuli and to examine gustatory receptor neurons and their immediate followers

202 : (1) initially encoded in the population of gustatory receptor neurons as broadly distributed spatio

203 The importance of cGMP in the ASE gustatory receptor neurons of the nematode Caenorhabditi

204 n channel was a direct target for camphor in gustatory receptor neurons, and long-term feeding on a c

205 investigate the function of pharyngeal sweet gustatory receptor neurons, demonstrating that they expr

206 y, we found that neurons expressing Gr66a, a gustatory receptor normally involved in avoidance behavi

207 s the directionally asymmetric expression of gustatory receptor proteins in the ASE neurons and the a

208 hese neurons express many drivers of the Gr (Gustatory receptor) family.

209 Here we identify homologues of GRs (Gustatory receptor-like (Grl) genes) in genomes across P

210 proteins, including odorant receptors (ORs), gustatory receptors (GRs) and ionotropic receptors (IRs)

211 Drosophila sweet neurons express eight gustatory receptors (Grs) belonging to a highly conserve

212 ionotropic receptors (IR) and in some cases gustatory receptors (GRs).

213 Gustatory receptors and peripheral taste cells have been

214 Gustatory receptors are a large gene family, widely stud

215 With other fly gustatory receptors having been shown to act in the dete

216 We discuss the identification of odorant and gustatory receptors in Glossina morsitans morsitans and

217 However, the minimal subunit composition of gustatory receptors required for sensing aversive chemic

218 quences representing putative ionotropic and gustatory receptors were also identified.

219 rain, and light, the roles of the so-called 'gustatory receptors' clearly go way beyond peripheral de

220 Here we report that three gustatory receptors, GR8a, GR66a and GR98b function toge

221 scular junction and reliable activation of a gustatory reflex pathway.

222 hough the basolateral amygdala (BLA) and the gustatory region of insular cortex (IC) have been implic

223 us), whereas a low-fat meal increased CBF in gustatory regions (anterior insula).

224 caused greater activation in the putamen and gustatory regions than did fat, increasing sugar caused

225 increasing sugar caused greater activity in gustatory regions, and increasing fat did not affect the

226 t sugar more effectively recruits reward and gustatory regions, suggesting that policy, prevention, a

227 ssociated brain responses in homeostatic and gustatory regions.

228 and weaker connectivity with homeostasis and gustatory-related brain regions than lean women.

229 : Our study provides a functional mapping of gustatory representation in the insular posterior short

230 ar region that partially overlapped with the gustatory representation.

231 Our work provides insight into gustatory representations in the mushroom bodies, reveal

232 in host vitellogenin, insulin signaling, and gustatory response.

233 we provide a functional mapping of olfactory-gustatory responses to stimulation of the human insular

234 GHSR-positive neurons were observed in the gustatory rostral nucleus tractus solitarius and in area

235 rh2 was restricted to the putative secondary gustatory/secondary visceral nucleus, which also express

236 the thalamus, the thalamic relay nucleus for gustatory sensation, receives primary input from the par

237 Gustatory sensations were evoked in 15 (2.7%) of the 550

238 While gustatory sensing of the five primary flavors (sweet, sa

239 lation of appetitive and aversive peripheral gustatory sensitivity permits flexible, adaptive feeding

240 owever, ultimately constrained by pollinator gustatory sensitivity.

241 rosophila brain processes mechanosensory and gustatory sensory input from sensilla located on the hea

242 ensory receptors regulate Galpha pathways in gustatory sensory neurons that extend cilia through the

243 che-6 mutants show defects in gustatory sensory transduction that are similar to defec

244 y downstream effector of the rGC proteins in gustatory signal transduction, a previously uncharacteri

245 n the concurrent processing of olfactory and gustatory signals from the mouth.

246 EZ), suggesting integration of olfactory and gustatory signals occurs in this brain region.

247 his work provides an example of how discrete gustatory signals recruit nutrient-dependent endocrine s

248 te-specific neurons: those that responded to gustatory stimulation and to the cue (i.e., cue-and-tast

249 Finally, we calculated when the gustatory stimulation phase is short or absent.

250 cumulative intake that universally describes gustatory stimulation, satiation, and maximal food intak

251 l for cumulative intake curves that captures gustatory stimulation, satiation, and maximal food intak

252 atic functions have not simultaneously taken gustatory stimulation, satiation, and maximal food intak

253 aminergic neurons phenocopies the absence of gustatory stimulation, suggesting a specific role for th

254 h ArchT) to demonstrate that, indeed, during gustatory stimulation, taste-selective information is tr

255 Receptor cells secrete acetylcholine during gustatory stimulation.

256 olfactory processing even in the absence of gustatory stimulation: GCx alters PC responses to olfact

257 the network of areas involved in processing gustatory stimuli and demonstrate significant difference

258 Gustatory stimuli are detected by taste buds and transmi

259 In natural conditions, gustatory stimuli are typically expected.

260 Gustatory stimuli were presented to rats either alone or

261 mPFC can encode the chemosensory identity of gustatory stimuli.

262 rom those that innervated the rostrocentral, gustatory subdivision.

263 while umami sensor responses were related to gustatory sweetness, bitterness and umami, as well as an

264 Here we show that the Drosophila gustatory system also affects lifespan in a bidirectiona

265 underscore the remarkable plasticity of the gustatory system and also help clarify the functional an

266 hypothesized that changes in the peripheral gustatory system are responsible for glucose aversion.

267 eurotrophins exert their unique roles on the gustatory system by regulating different sets of downstr

268 neurons provides one mechanism by which the gustatory system differentially encodes aversive and att

269 Animals' gustatory system has been widely acknowledged as one of

270 The gustatory system is ideal for examining this issue becau

271 s inedibility, the potential to use rodent's gustatory system is investigated to detect bitter compou

272 anssynaptic tracer barley lectin (BL) in the gustatory system of mice.

273 ophysiological recordings from the tractable gustatory system of the moth Manduca sexta, we found che

274 The gustatory system provides vital sensory information to d

275 Recent work in the mouse gustatory system showed that selectively deleting the pr

276 Here, we used the Drosophila melanogaster gustatory system to dissect one component of sensory reg

277 In the gustatory system, experimental manipulations now exist,

278 wo types of neurons in the rodent peripheral gustatory system, Na specialists (NS) and acid generalis

279 vel method for calcium imaging in the larval gustatory system, we identify a multimodal GRN that resp

280 actory system and then implemented it in the gustatory system, where projections beyond the first-ord

281 f neurons in the first neural station of the gustatory system.

282 uality representations and perception in the gustatory system.

283 nd functional organization of the peripheral gustatory system.

284 ining structural integrity of the peripheral gustatory system.

285 s modulate the functioning of the peripheral gustatory system.

286 are consistent with an emerging view of the gustatory system: rather than constructing basic taste c

287 tle is known about how acids are detected by gustatory systems and whether they have a potential role

288 reasing neural activity in the olfactory and gustatory systems in animals across phyla.

289 ransduction and coding of information by the gustatory systems of vertebrates and invertebrates.

290 Similarities between the gustatory systems of zebrafish and other fishes are also

291 Alas, virtually nothing is known on how the gustatory thalamus (VPMpc) processes gustatory informati

292 To reveal the unique properties of the gustatory thalamus in comparison with archetypical senso

293 ormation is available on the function of the gustatory thalamus in shaping GC activity.

294 In accordance, lesions of the gustatory thalamus or cortex eliminate avoidance of a ta

295 medial nucleus of thalamus (VPMpc; i.e., the gustatory thalamus).

296 g unique anatomical properties of the rodent gustatory thalamus.

297 urnover cycle, our data suggest that chicken gustatory tissue provides an ideal system for multidisci

298 d the transcriptomic architecture of chicken gustatory tissues.

299 n 1) second-order sensory neurons processing gustatory, vestibulo-ocular, and visceral sensation; 2)

300 eful for characterizing a putative secondary gustatory/visceral nucleus in the isthmus, and for disti