ライフサイエンスコーパス: gut

1 mescales of host-microbe interactions in the gut.

2 are not typically retrieved from the chicken gut.

3 lexity relative to other niches, such as the gut.

4 microbial community structure in an infant's gut.

5 ormal accumulation of apoptotic cells in the gut.

6 he biogeography of symbiotic bacteria in the gut.

7 wn to provide colonization resistance in the gut.

8 central homeostatic mechanism of the insect gut.

9 nge the balance of commensal bacteria in the gut.

10 the gastro-oesophageal junction in the human gut.

11 n in the fruit fly (Drosophila melanogaster) gut.

12 ia, including those in the mouth, lungs, and gut.

13 also interact with bacteria in the mammalian gut.

14 major source of nutrients for E. coli in the gut.

15 increasing the stability of higher-diversity guts.

16 the lungs after helminth infection or in the gut after induction of colitis.

17 ons is challenging because genetic tools for gut anaerobes are limited.

18 relationship between the microbiota in mouse gut and diet type.

19 Vgamma9/Vdelta2 T cells are abundant in the gut and recognize microbiota-associated metabolites, we

20 the study, four were detected in both infant gut and room samples.

21 oorganisms (microbiota), particularly in the gut, and at least 20% of the small molecules in human bl

22 DNA in blood, lymph nodes (LN), spleen, and gut, and contained replication-competent and infectious

23 mation within diabetic islets, brain, liver, gut, and muscle; the role of inflammation in fibrosis an

24 The lymphoid tissues of the gut are specialized for the induction of regulatory cell

25 Insect gut-associated microbes modulating plant defenses have b

26 h must integrate each component of the brain-gut axis and the influence of biological sex, early-life

27 ic targeting of the gut microbiota for brain-gut axis disorders, opening new avenues in the field of

28 tion of neurotoxicants that affect the brain-gut axis via the vagus nerve, and then travel to higher

29 ABX significantly reduced gut bacteria and prevented chronic morphine induced incr

30 mmunities, we observed widespread sharing of gut bacteria between predator-prey host-species pairs, i

31 We previously showed that symbiotic gut bacteria from CPB larvae suppressed jasmonate (JA)-i

32 (2017) report the identification of specific gut bacteria that protect from Salmonella infection by p

33 This study identifies specific human gut bacteria that regulate adaptive autoimmune responses

34 ies pairs, indicating horizontal transfer of gut bacteria through mammalian food chains.

35 provide a proof of concept that introducing gut bacteria to a herbivore may provide a novel approach

36 be restored through oral transfer of control gut bacteria to antibiotic-treated animals.

37 intestinal permeability and translocation of gut bacteria trigger various polyaetiological diseases a

38 We review the mechanisms by which these gut bacteria, fungi, and viruses mediate mucosal homeost

39 ence for diet-associated RI, for any role of gut bacteria, or for L. plantarum specifically.

40 inate and 1,2-propanediol) between different gut bacteria.

41 lth of an infant as substrate for beneficial gut bacteria.

42 nstrate that host plants influence herbivore gut bacterial communities and consequently affect the he

43 The gut bacterial communities of mammals have profound effec

44 relative abundance of taxonomic units in the gut bacterial community.

45 Overall, our study suggests that increasing gut bacterial diversity and relative abundances of Fusob

46 but the processes that generate and maintain gut bacterial diversity remain poorly understood.

47 post-inoculation to determine the effect on gut bacterial diversity.

48 of phylogenetically diverse, sequenced human gut bacterial strains introduced into adult gnotobiotic

49 Here we show that the gut bacterium Bacteroides thetaiotaomicron uses the most

50 a quantitative perspective of the early-life gut Bifidobacterium colonization and shows how factors s

51 tinal cell suspensions and ILC3s sorted from gut biopsy specimens of patients with IBD were also anal

52 otility, and metabolites that stimulate the "gut-brain axis" to alter neural circuits, autonomic func

53 l pathways through the highly interconnected gut-brain axis.

54 and peripheral immune pathways in microbiota-gut-brain communication during health and neurological d

55 ders (FGIDs), now recognized as disorders of gut-brain interaction.

56 te directly to CDI-associated lesions of the gut, but other bacterial factors are needed for the bact

57 y help explain the preferential infection of gut CD4(+) T cells.

58 romised flies with higher bacterial load and gut cell death.

59 hether barrier deregulations, similar to the gut, characterize other vital organs in obese individual

60 We designed a board game called "Gut Check: The Microbiome Game" to fill this gap.

61 In contrast, in a mouse gut colonization model in which the natural microbiota i

62 ss-diverse microbiome and loss of protective gut commensal strains (of the family Lachnospiraceae) an

63 Bifidobacteria are common gut commensals with purported health-promoting effects.

64 A dysfunctional sympathetic-gut communication is associated with gut pathology, dysb

65 results on the potential involvement of bee gut communities in pathogen protection and nutritional f

66 sure on the size and composition of honeybee gut communities.

67 a that is spatially organized into different gut compartments.

68 hemselves to morphological identification of gut contents, such as spiders.

69 -containing IgG immune complexes (Ig-ICs) by gut dendritic cells (DCs).

70 lammation, which is believed to be driven by gut-derived inflammatory mediators carried via mesenteri

71 de-1 highlights the therapeutic potential of gut-derived signals acting via nonphysiologic mechanisms

72 However, it is still largely unknown how gut dysbiosis affects the onset and progression of CNS a

73 Current efforts are directed to reducing the gut dysbiosis and inflammation produced by obesity.

74 ave been reported on whether AgNPs result in gut dysbiosis and other changes within the host.

75 We show here that the induction of gut dysbiosis triggers the development of spontaneous ex

76 Consequently, gut dysbiosis was able to trigger the development of enc

77 lication of cirrhosis and is associated with gut dysbiosis.

78 the effects of such compounds on developing gut endocrine and neuroendocrine systems.

79 and how MFSD2A regulates lipid metabolism of gut endothelial cells to promote resolution of intestina

80 Microbial diversity in the gut ensures robustness of the microbiota's ability to ge

81 strategy of C. difficile in the challenging gut environment still remains incompletely understood.

82 Microbial exposures and gut environmental conditions differ between infants in d

83 the importance of postmitotic cell growth in gut epithelial repair.

84 Both the compounds improved the gut epithelium by promoting goblet and Paneth cells popu

85 The gut epithelium is a principal site for detecting such ag

86 strates that autocrine IL-6 signaling in the gut epithelium regulates crypt homeostasis through the P

87 The mouse gut epithelium represents a constitutively challenged en

88 interactions among the microbiota, immunity, gut function, and behavior.

89 protein adequacy as well as energy intakes, gut function, clinical outcomes, and how well nutritiona

90 7A/B, localizes to lysosome-like organelles (gut granules) in the intestine under copper overload con

91 with cell types, and uncovers principles of gut homeostasis and response to pathogens.

92 Gut homeostasis is a tightly regulated process requiring

93 the intestinal lamina propria contribute to gut homeostasis through the immunomodulatory interleukin

94 and autoantibody responses by increasing the gut-homing alpha4beta7 integrin expression on Tfh cells.

95 disruption of retinoid homeostasis affected gut-homing and differentiation of lymphocytes and displa

96 ABSTACT: The gut hormone glucagon-like peptide (GLP)-1 and its analog

97 -dependently slow gastric emptying and alter gut hormone secretion compared with a control but have n

98 trasonography), and blood glucose and plasma gut-hormone concentrations [insulin, glucagon, ghrelin,

99 dministration of a long-acting analog of the gut-hormone glucagon-like peptide-1 highlights the thera

100 arnesoid X receptor and TGR5, the BA-induced gut hormones, fibroblast growth factor 19 and glucagon-l

101 We found that gut IgM(+) plasma cells (PCs) were more abundant in huma

102 tune adequate physiological processes in the gut in health and disease.

103 y B cells due to their redistribution to the gut, increases of the activated B cells and circulating

104 w that CX3CR1-deficient mice fail to resolve gut inflammation despite high production of IL10 and hav

105 anisms by which Entamoeba histolytica drives gut inflammation is critical for the development of impr

106 lism or indirectly via parasite induction of gut inflammation.

107 Urinary fluorophore and sugar ratios reflect gut injury in an indomethacin dose dependent manner.

108 Hirschsprung disease, leading to absence of gut innervation and severe gastrointestinal symptoms.

109 There is increasing evidence that brain-gut interactions are altered during development of infla

110 The same compound promotes gut iron absorption in DMT1-deficient rats and ferroport

111 Although whole gut irradiation with these doses caused lethal GI syndro

112 ding pH-shift produced protein isolates from gutted kilka (Clupeonella cultriventris) and silver carp

113 The previously unidentified Gut-Liver-Bone Axis intriguingly implies the normal gut

114 collected and microbiota were analyzed using Gut Low-Density Array quantitative polymerase chain reac

115 n the initial propagation of prions from the gut lumen into Peyer's patches.

116 companied by increased formate levels in the gut lumen.

117 substantially elevated lactate levels in the gut lumen.

118 nt of gut microbiota in lung diseases by the gut-lung axis has been widely observed, but the underlyi

119 DNA viral community from publicly available gut metagenome data sets from human populations with dif

120 The human gut metagenome was recently discovered to encode vast co

121 be driven by pro-nociceptive changes in the gut micro-environment.

122 We found no evidence that gut microbe community composition was associated with ca

123 A specific human-associated gut microbe, Clostridium orbiscindens, produced DAT and

124 Highlighted here, the gut microbe-derived metabolite trimethylamine N-oxide ha

125 Here, we demonstrate that gut microbes from the sand fly are egested into host ski

126 es of 2 self-proteins and a related order of gut microbes may provide a link between mucosal and join

127 infections exert on populations of commensal gut microbes of veterinary species is a field of researc

128 n can affect the composition and function of gut microbes.

129 Metabonomic studies implicated variations in gut microbial activities that mapped onto tacrine-induce

130 l stiffness and exerts a beneficial shift in gut microbial communities in a rat model that mimics hum

131 ducing dysbiosis and that the FODMAP-altered gut microbial community leads to intestinal pathology.

132 al roles in animal health, and shifts in the gut microbial community structure can have detrimental i

133 l sociality) are associated with patterns of gut microbial composition (diversity and similarity) bet

134 in strong responders, based on differential gut microbial composition (e.g., Lactobacillus, Bacteroi

135 position within the social network predicted gut microbial composition.

136 hensive strain-level genetic overview of the gut microbial diversity.

137 Patients were characterized by a form of gut microbial dysbiosis that is more prominent than prev

138 Prior work on gut microbial time series has largely focused on autoreg

139 163), soluble CD14 (sCD14), CRP, IL-6, and a gut microbial translocation marker (intestinal fatty aci

140 hanges in circulating metabolites, including gut microbial, tryptophan, plant component, and gamma-gl

141 annotation of a diversity of endogenous and gut microbially derived metabolites affected by both die

142 It is a matter of fact that the human gut microbiome also includes a non-bacterial fraction re

143 his article we review the current methods of gut microbiome analysis and the resulting data regarding

144 etween observed dramatic fluctuations in the gut microbiome and intensified medication due to a flare

145 gated the impact of diazinon exposure on the gut microbiome composition and its metabolic functions i

146 Characterisation of marine copepod gut microbiome composition and its variability provides

147 stance to ICIs can be attributed to abnormal gut microbiome composition.

148 gnificant role in the evolution of mammalian gut microbiome compositions.

149 evaluate the effects of azithromycin on the gut microbiome diversity of children from an antibiotic-

150 tributed to a deregulated immune response to gut microbiome dysbiosis.

151 ry analyses of neuroimaging data suggest the gut microbiome has minimal effects on regional brain vol

152 The components of the human gut microbiome have been found to influence a broad arra

153 nt in order to determine if dysbiosis of the gut microbiome impacts honeybee health, and we performed

154 iet rich in fat and simple sugars alters the gut microbiome in a manner that contributes to host adip

155 our results highlight the importance of the gut microbiome in honeybee health, but they also provide

156 re we show that high salt intake affects the gut microbiome in mice, particularly by depleting Lactob

157 or further investigations on the role of the gut microbiome in promoting or preventing ACVD as well a

158 e composition and functional capacity of the gut microbiome in relation to cardiovascular diseases ha

159 ich integrates unique information about host-gut microbiome interactions, gastrointestinal functional

160 definitively decreases the diversity of the gut microbiome of children in an antibiotic-naive commun

161 The gut microbiome plays a central role in inflammatory bowe

162 Nutrition and the gut microbiome regulate many systems, including the immu

163 searchers in experimental design choices for gut microbiome studies.

164 ew the evidence linking perturbations of the gut microbiome to pancreatic autoimmunity.

165 with our intestinal counterpart, pushing the gut microbiome toward a dysbiotic layout, where microbio

166 To further explore the gut microbiome variation in human populations, here we c

167 Diversity of the gut microbiome was significantly lower in the treated gr

168 Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosacc

169 ia effects on (a) circadian biology, (b) the gut microbiome, and (c) modifiable lifestyle behaviors,

170 This study reveals the gut microbiome-mediated diabetogenic nature of organopho

171 ey metabolites and signaling molecules (e.g. gut microbiome-to-intestine-to-blood-to-liver-to-kidney-

172 in the CNS may start with modulation of the gut microbiome.

173 ivities from bacterial neighbours within the gut microbiome.

174 the dietary lipid content may influence the gut microbiome.

175 Antibiotic exposure can alter the gut microbiome.

176 tion, and perhaps through alterations in the gut microbiome.

177 k and areolar skin microbiomes to the infant gut microbiome.

178 e tests for RI associated with diet-specific gut microbiomes in D. melanogaster Despite observing rep

179 pite observing replicable differences in the gut microbiomes of flies maintained on different diets,

180 Gut microbiomes play crucial roles in animal health, and

181 limited studies in understanding the role of gut microbiota (GM) in viral-associated diarrhea.

182 ve disease removed harmful bacteria from the gut microbiota and attenuated SLE-like disease in lupus-

183 tudy to demonstrate associations between the gut microbiota and cognition in human infants.

184 s, as a critical factor that is regulated by gut microbiota and determines thrombus growth in Tlr2(-/

185 by the host for diet-induced changes of the gut microbiota and energy metabolism.

186 Accordingly, both the gut microbiota and immune system are implicated in the e

187 Nopal modified gut microbiota and increased intestinal occludin-1 in th

188 stablishing a strong association between the gut microbiota and obesity in humans, a causal relations

189 We examined the impact of IS drugs on gut microbiota and on the expression of ileal antimicrob

190 Communication pathways between gut microbiota and the central nervous system could incl

191 Gut microbiota and the immune system interact to maintai

192 vealed that Clostridia added to mouse infant gut microbiota are sufficient to limit colonization of p

193 In conclusion, drug discovery targeting the gut microbiota as well as the characterization of microb

194 rmula with specific prebiotics modulated the gut microbiota closer to that of breast-fed infants.

195 role of fat content in the diet in altering gut microbiota community by shifting phylotype compositi

196 Thus, ultrafine particles ingestion alters gut microbiota composition, accompanied by increased ath

197 in both the intestine and plasma via altered gut microbiota composition.

198 An aberrant IgA responsiveness to the gut microbiota during infancy precedes asthma and allerg

199 The human gut microbiota ferments dietary non-digestible carbohydr

200 base supporting therapeutic targeting of the gut microbiota for brain-gut axis disorders, opening new

201 Gut microbiota has a proven role in regulating multiple

202 The gut microbiota have been linked with the development of

203 ability of prebiotics to specifically modify gut microbiota in children with overweight/obesity or re

204 Development of the gut microbiota in infancy is important in maturation of

205 Involvement of gut microbiota in lung diseases by the gut-lung axis has

206 iological variable in studies on the role of gut microbiota in obesity-related mood disorders.

207 The evidence on the role of gut microbiota in post-infectious irritable bowel syndro

208 vidence has revealed the pivotal role of the gut microbiota in shaping the immune system.

209 siological activities, and the importance of gut microbiota in supplying micronutrients to animals.

210 Transfer of antibiotic-modified gut microbiota inhibits CS, but this response can be res

211 The gut microbiota is implicated in numerous aspects of heal

212 The human gut microbiota makes key contributions to the metabolism

213 Gut microbiota may be altered in patients with cirrhosis

214 g ACVD as well as other related diseases.The gut microbiota may play a role in cardiovascular disease

215 Further, some of the predicted pomegranate gut microbiota metabolites modulated (14)C-D-glucose and

216 Different factors may modulate the gut microbiota of animals.

217 als in different locations may influence the gut microbiota of infants.

218 In females, stress caused the gut microbiota of lean mice to more closely resemble tha

219 flies with constitutive immunity defined the gut microbiota of their cohabitants.

220 ing immune system and the not-yet-stabilized gut microbiota of young children to facilitate its persi

221 The symbiotic gut microbiota play pivotal roles in host physiology and

222 Finally, the gut microbiota produces molecules that act on enteric ne

223 We found that gut microbiota promotes the development of chemotherapy-

224 Despite knowledge the gut microbiota regulates bone mass, mechanisms governing

225 Science, Wang et al. (2017) reveal that the gut microbiota regulates the expression of circadian-clo

226 in Ruminococcus and Dorea were identified as gut microbiota signatures of NAFL onset and NAFL-NASH pr

227 polysaccharides play extensive roles in host-gut microbiota symbiosis beyond dietary polysaccharide d

228 A diet high in fiber led to changes in the gut microbiota that played a protective role in the deve

229 g cells (pAPCs) recognize and respond to the gut microbiota through multiple pattern-recognition rece

230 ce elements such as copper and zinc, altered gut microbiota to more pathogenic bacteria, increased in

231 The contribution of the gut microbiota to the metabolism of cholesterol is not w

232 The human gut microbiota utilizes complex carbohydrates as major n

233 The composition of gut microbiota was assessed by sequencing the 16S rRNA g

234 er-Bone Axis intriguingly implies the normal gut microbiota's osteoimmunomodulatory actions are partl

235 s bone mass, mechanisms governing the normal gut microbiota's osteoimmunomodulatory effects on skelet

236 hormonal imbalances, metabolic disturbances, gut microbiota, and cancer.

237 Because HMOs, gut microbiota, and infant health are interrelated, the

238 ints to a strong association between sex and gut microbiota, bile acids (BAs), and gastrointestinal c

239 tibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adapt

240 iminution correlates with alterations in the gut microbiota, particularly enrichment of Propionibacte

241 tis model, we show that a constituent of the gut microbiota, segmented filamentous bacteria (SFB), di

242 bution of one of the main metabolites of the gut microbiota, the short-chain fatty acid acetate.

243 nate antimicrobial defenses and disrupts the gut microbiota, which leads to overgrowth of indigenous

244 Food deprivation also challenges the gut microbiota, which relies heavily on host diet for me

245 ractions occurring between parasites and the gut microbiota, with a profound impact on both host immu

246 asma trimethylamine N-oxide (TMAO) levels, a gut microbiota-dependent metabolite associated with coro

247 cant interest in recent years has focused on gut microbiota-host interaction because accumulating evi

248 tribution of resident gut microorganisms-the gut microbiota-to human health has surged.

249 ides thetaiotaomicron, a member of the human gut microbiota.

250 al health and performance through modulating gut microbiota.

251 mers drives microbial diversity in the human gut microbiota.

252 s are major nutrients available to the human gut microbiota.

253 and abundances of various bacterial taxa in gut microbiota.

254 ritionally complete diet in the absence of a gut microbiota.

255 srupting the structural configuration of the gut microbiota.

256 Diabetes has a significant impact on the gut microbiota; however, studies in the oral cavity have

257 ludes luminal content, senses changes in the gut microenvironment, and releases immune regulators tha

258 ppreciation for the contribution of resident gut microorganisms-the gut microbiota-to human health ha

259 n essential non-classical role in vertebrate gut morphogenesis.

260 tem neuropathy causes a wide range of severe gut motility disorders.

261 iremia, and virus was isolated from tonsils, gut mucosa, and draining lymph nodes.

262 ated surfaces of the body, in particular the gut mucosa, are the major sites where immune cells traff

263 many pathophysiological processes, including gut mucosal adaptation.

264 The functional relevance of the gut mycobiome was confirmed in fecal transplantation exp

265 sis), consistent with a single origin of the gut, nerve cells, and muscle cells in the stem lineage o

266 he most important enteropathogen involved in gut nosocomial post-antibiotic infections.

267 Inhibiting the activity of Pol III in the gut of adult worms or flies is sufficient to extend life

268 Recolonizing the gut of middle-age individuals with bacteria from young d

269 without detectable fitness burden within the gut over 14 days.

270 tem in maintaining immune homeostasis in the gut/pancreas and reveals a conversation between the nerv

271 phimurium creates a favorable niche for this gut pathogen.

272 associated with amelioration of age-related gut pathology and functional decline, dampened protein s

273 These changes in gut pathology in hypertension were associated with alter

274 athetic-gut communication is associated with gut pathology, dysbiosis, and inflammation and plays a k

275 a hallmark of CD, and anti-TG2 IgA-producing gut PCs accumulate in patients upon gluten ingestion.

276 1482 TG2-specific and 1421 non-TG2-specific gut PCs from 10 CD patients.

277 evidence to the EE hypothesis that increased gut permeability and inflammation adversely affects subs

278 vented chronic morphine induced increases in gut permeability, colonic mucosal destruction, and colon

279 o intestinal barrier damage/dysfunction, and gut permeability.

280 carboxylic acid, improving DGAT1 potency and gut permeability.

281 ous mechanical and chemical stimuli in nerve-gut preparations in mouse, or following antagonism of Na

282 toxins bind sequentially to different larval gut proteins facilitating oligomerization, membrane inse

283 The gut receives significant sympathetic innervation, is den

284 This index increased at all gut regions during the duration of infection, including

285 Within the human gut reside diverse microbes coexisting with the host in

286 The healthy gut restricts macromolecular and bacterial movement acro

287 Within the gut, Salmonella-infected enterocytes are expelled into t

288 An unexplained observation is that gut species composition varies widely between individual

289 In addition to sharing a gut-specific gene signature with memory IgA(+) B cells,

290 duced T-cell clonotypes from total blood and gut TCR repertoires in an unbiased manner using immunose

291 troduction of beta-cell autoantigens via the gut through Lactococcus lactis (L. lactis) has been demo

292 With an ex vivo model using human gut tissue specimens, we showed a dose-responsive GLP-1

293 ers (Slc10a2, Slc51a) and increases in whole gut transit time and intestinal permeability.

294 , as shown by the reductions of FITC-dextran gut translocation, serum interleukin-6 (IL-6) levels, ba

295 ired for DHA retention and metabolism in the gut vasculature.

296 at investigating the biological role of the gut virome in human physiology, and the importance of ou

297 Carbenoxolone also prevented gut wall disruption and significantly reduced morphine-i

298 ogy of cancers in different locations of the gut, where colon cancer is primarily driven by inflammat

299 GF or HGF expanded into self-organizing mini-guts with similar levels of efficacy and contained all d

300 ritis in approximately 50% of infected human gut xenografts.