ライフサイエンスコーパス: gut microbiome

1 the dietary lipid content may influence the gut microbiome.

2 an appropriate milk-digestive and protective gut microbiome.

3 k and areolar skin microbiomes to the infant gut microbiome.

4 ine the functional impact of diazinon on the gut microbiome.

5 rse bacteria, including members of the human gut microbiome.

6 behavioral, and phylogenetic effects on the gut microbiome.

7 osity in animal models, mediated through the gut microbiome.

8 cial immune responses through optimizing the gut microbiome.

9 des, the dominant genera in the modern human gut microbiome.

10 sues, sympathetic response pathways, and the gut microbiome.

11 stinal inflammation that is dependent on the gut microbiome.

12 t-induced-obesity-mediated alteration of the gut microbiome.

13 rom the metabolism of dietary choline by the gut microbiome.

14 o increasing the proteolytic activity of the gut microbiome.

15 ost genetics are likely to influence the pig gut microbiome.

16 Antibiotic exposure can alter the gut microbiome.

17 ration and lifestyle disruption on the human gut microbiome.

18 d to investigate metabolic capacities in the gut microbiome.

19 discriminate between age groups in the human gut microbiome.

20 unctional potential of an individual's human gut microbiome.

21 tive analysis of specific genes in the human gut microbiome.

22 e emerging field of the role of fungi in the gut microbiome.

23 nerated a metatranscriptome of the honey bee gut microbiome.

24 tion of body weight, glucose homeostasis and gut microbiome.

25 d in maintaining host circadian rhythms, the gut microbiome.

26 and variation of specific genes in the human gut microbiome.

27 ironmental exposures, and alterations in the gut microbiome.

28 ntity, 90% coverage) with those of the human gut microbiome.

29 in the CNS may start with modulation of the gut microbiome.

30 ivities from bacterial neighbours within the gut microbiome.

31 ssociated with an altered composition of the gut microbiome.

32 tion, and perhaps through alterations in the gut microbiome.

33 cals can exert toxic effects on the host and gut microbiome.

34 implications from inflammatory states to the gut microbiome.

35 oth the size and composition of the honeybee gut microbiome.

36 ological parameters in part by affecting the gut microbiome.

37 eastfeeding in the development of the infant gut microbiome.

38 tion for accurate characterization of infant gut microbiomes.

39 Treponema are characteristic of traditional gut microbiomes.

40 d BIOM file for an entire MiSeq run of human gut microbiome 16S genes in under 10 minutes on a dual-c

41 ow that LXG genes are prevalent in the human gut microbiome, a polymicrobial community dominated by F

42 Disruption of this gut microbiome, a process known as dysbiosis, causes or

43 uch-expanded perspective on variation in the gut microbiome across species and ecological contexts.

44 major branches of biosynthesis, catabolism, gut microbiome activities, and xenobiotics.

45 esent one of the main mechanisms whereby the gut microbiome affects vertebrate physiology, and they a

46 However, alterations in the gut microbiome after liver transplantation and the impli

47 rends in the development of the human infant gut microbiome along with specific alterations that prec

48 It is a matter of fact that the human gut microbiome also includes a non-bacterial fraction re

49 observations advance the novel concept that gut microbiome alterations caused by early-life exposure

50 his article we review the current methods of gut microbiome analysis and the resulting data regarding

51 To investigate the relationship between the gut microbiome and ankylosing spondylitis, a quantitativ

52 yptophanases encoded by members of the human gut microbiome and demonstrate that levels of the uremic

53 ents and iron fortification with MNPs on the gut microbiome and diarrhea.

54 y (CD) perturbs the assembly of the neonatal gut microbiome and has been associated with child and ad

55 etween observed dramatic fluctuations in the gut microbiome and intensified medication due to a flare

56 rocesses in human health, aberrations in the gut microbiome and intestinal homeostasis have the capac

57 ovel insights regarding perturbations of the gut microbiome and its functions as a potential new mech

58 Therefore, the gut microbiome and its interaction with the host influen

59 c effects of organophosphate diazinon on the gut microbiome and its metabolic functions.

60 of environmental toxicants in perturbing the gut microbiome and its metabolic functions.

61 urinary tract infections (UTIs) disrupt the gut microbiome and promote antibiotic resistance.

62 y, stressors, and diet can all influence the gut microbiome and promote intestinal permeability, anot

63 e of the most abundant bacteria in the human gut microbiome and that are also common in various other

64 Nevertheless, little is known about the gut microbiome and the factors that contribute to microb

65 redicted both the taxonomic structure of the gut microbiome and the structure of genes encoded by gut

66 versity, composition and structure of kogiid gut microbiomes and indicate that host identity plays an

67 ia effects on (a) circadian biology, (b) the gut microbiome, and (c) modifiable lifestyle behaviors,

68 hese mechanisms include the influence of the gut microbiome, and also metabolic, genetic, and immunol

69 reveals intricate pathways linking diet, the gut microbiome, and intestinal barrier dysfunction, whic

70 iazinon exposure significantly perturbed the gut microbiome, and metagenomic sequencing found that di

71 mption is associated with alterations in the gut microbiome, and the dysbalance of pathogenic and com

72 By altering the community structure of the gut microbiome, antibiotics alter the intestinal metabol

73 en applied to the IGC gene catalogs in human gut microbiome ( approximately 10M genes), DACE produced

74 Alterations of the gut microbiome are associated with development of ankylo

75 ake to the gut-immune axis and highlight the gut microbiome as a potential therapeutic target to coun

76 al support for considering modulation of the gut microbiome as a primary asthma prevention strategy.

77 othelial Toll-like receptor 4 (TLR4) and the gut microbiome as critical stimulants of CCM formation.

78 nity in responding patients with a favorable gut microbiome as well as in germ-free mice receiving fe

79 differences, dietary and composition of the gut microbiome, as well as biologic and genetic influenc

80 Bile acids are emerging as regulators of the gut microbiome at the highest taxonomic levels.

81 neurological function is nascent, unraveling gut-microbiome-brain connections holds the promise of tr

82 We examined the gut microbiome by PhyloChip G3 from 16 NMO patients, 16

83 s a surge of evidence has suggested that the gut microbiome can have tremendous impact on behavioral

84 Gut microbiome, cardiorenal structure/function, and bloo

85 omarkers, as the composition and activity of gut microbiome change with many factors, particularly wi

86 The gut microbiome changes modulated host lipid processing b

87 e to AgNS or AgNC can lead to behavioral and gut microbiome changes.

88 dition, we illustrate how a putative minimal gut microbiome community could be represented in our fra

89 Diazinon exposure perturbed the gut microbiome community structure, functional metagenom

90 is study was to reveal relationships between gut microbiome composition and circulating metabolic hor

91 n common chronic human disorders and altered gut microbiome composition and function have been report

92 gated the impact of diazinon exposure on the gut microbiome composition and its metabolic functions i

93 Characterisation of marine copepod gut microbiome composition and its variability provides

94 This study shows novel relationships between gut microbiome composition and the metabolic hormonal en

95 Gut microbiome composition at age 3 to 6 months was asso

96 Shifts in gut microbiome composition have also been associated wit

97 ltiple factors were associated with neonatal gut microbiome composition in both single- and multi-fac

98 As the first series of genetic analyses of gut microbiome composition in humans is now emerging, th

99 interactions are an important determinant of gut microbiome composition in natural animal populations

100 Although gut microbiome composition is well defined, the mechanis

101 ese results suggest that manipulation of the gut microbiome composition may influence pregnancy metab

102 We examined the oral and gut microbiome composition of two captive koalas to dete

103 vitamin D levels are associated with infant gut microbiome composition, with possible long-term impl

104 addition to small but significant shifts in gut microbiome composition.

105 immune response to mucosal injury and on the gut microbiome composition.

106 stance to ICIs can be attributed to abnormal gut microbiome composition.

107 gnificant role in the evolution of mammalian gut microbiome compositions.

108 ggest that an SLC39A8-dependent shift in the gut microbiome could explain its pleiotropic effects on

109 The gut microbiome could modulate metabolic health and may a

110 Although liver and gut microbiome crosstalk has been reported, microbiome-m

111 We identify common themes by comparison with gut microbiome data associated with other cardiometaboli

112 age, a complete pipeline for the analysis of gut microbiome data.

113 ulation studies and the application to mouse gut microbiome data.

114 3% of its abundance is shared with the human gut microbiome despite the physicochemical differences b

115 We followed gut microbiome development from birth until age three in

116 The ACVD gut microbiome deviates from the healthy status by incre

117 Its bacterial gut microbiome differed significantly from its laborator

118 igate the links between omega-3 fatty acids, gut microbiome diversity and composition and faecal meta

119 ican Indian tribes in Oklahoma, and compared gut microbiome diversity and metabolic function of C&A p

120 LP-1 plasma concentration, and remodeling of gut microbiome diversity characterized by a lower relati

121 Reduced gut microbiome diversity is associated with multiple dis

122 evaluate the effects of azithromycin on the gut microbiome diversity of children from an antibiotic-

123 Here, we describe the first gut microbiome diversity study of an American Indian com

124 was to identify blood metabolite markers of gut microbiome diversity, and explore their relationship

125 ne growth, and causes progressive changes in gut microbiome diversity, population structure and metag

126 sociated with dramatic loss of natural human gut microbiome diversity, the causes and consequences of

127 To examine the relationship between human gut microbiome dynamics throughout infancy and type 1 di

128 These findings suggest that neonatal gut microbiome dysbiosis might promote CD4(+) T cell dys

129 tributed to a deregulated immune response to gut microbiome dysbiosis.

130 nd solutes, including those derived from the gut microbiome (e.g., CMPF, phenylsulfate, indole-3-acet

131 shed new light on the assembly of the infant gut microbiome early in life, and how diet and delivery

132 Gram-negative bacteria from the human gut microbiome encode a relative of the human endopeptid

133 eraction directly explained variation in the gut microbiome, even after controlling for diet, kinship

134 A novel risk model, including the gut microbiome explained </= 25.9% of high-density lipop

135 Furthermore, we assessed infant gut microbiomes for the presence of (pro)phage sequences

136 he acidic gut region protects the insect and gut microbiome from pathological disruption, and shed li

137 Indeed, the gut microbiome functions like an endocrine organ, genera

138 ay for a new era of rational piloting of the gut microbiome functions, through the design of a new ge

139 Thus, establishment of a comprehensive pig gut microbiome gene reference catalogue constitutes a lo

140 Similar to the human gut microbiome, >99% of the cataloged genes are bacteria

141 ations for lifelong gut health, and that the gut microbiome guides and/or facilitates these postnatal

142 The assessment and characterization of the gut microbiome has become a focus of research in the are

143 y intake, lifestyle, host phenotype, and the gut microbiome has enabled the development of a machine-

144 ry analyses of neuroimaging data suggest the gut microbiome has minimal effects on regional brain vol

145 The components of the human gut microbiome have been found to influence a broad arra

146 functional changes to the composition of the gut microbiome have been implicated in multiple human di

147 ion demonstrates probiotic modulation of the gut microbiome, highlights a novel gene network involved

148 abetes, liver dysfunction, and disruption of gut microbiome homeostasis were identified in several vo

149 with obesity and suggest profound changes in gut microbiome-host interactions after the surgery.

150 els in the interactions among the beta cell, gut microbiome, hypothalamus, innate and adaptive immune

151 Species compositions of gut microbiomes impact host health [1-3], but the proces

152 nt in order to determine if dysbiosis of the gut microbiome impacts honeybee health, and we performed

153 e we report a 16S rRNA-based analysis of the gut microbiome in 1,126 twin pairs, a subset of which wa

154 iet rich in fat and simple sugars alters the gut microbiome in a manner that contributes to host adip

155 w prenatal and early life factors impact the gut microbiome in a relatively large, ethnically diverse

156 whether dietary lipid content influences the gut microbiome in adult zebrafish.

157 More recently, a direct role for the gut microbiome in determining this type of RI in Drosoph

158 our results highlight the importance of the gut microbiome in honeybee health, but they also provide

159 ssect the long-term dynamic behaviour of the gut microbiome in IBD and differentiate this from normal

160 The gut microbiome in infancy influences immune system matur

161 re we show that high salt intake affects the gut microbiome in mice, particularly by depleting Lactob

162 ness is increasing regarding the role of the gut microbiome in modulating GI function.

163 Here, we report that the gut microbiome in mosquitoes utilizes C-type lectins (mo

164 Most recently, a role of the gut microbiome in pregnancy has been observed, with chan

165 or further investigations on the role of the gut microbiome in promoting or preventing ACVD as well a

166 Appreciation of the role of the gut microbiome in regulating vertebrate metabolism has e

167 e composition and functional capacity of the gut microbiome in relation to cardiovascular diseases ha

168 e use 16S rRNA sequencing to investigate the gut microbiome in subjects with multiple sclerosis (MS,

169 creases in colonic iron adversely affect the gut microbiome in that they decrease abundances of benef

170 Evidence for the role of the gut microbiome in the pathogenesis of non-alcoholic fatt

171 e tests for RI associated with diet-specific gut microbiomes in D. melanogaster Despite observing rep

172 mmunity structure analyses revealed distinct gut microbiomes in K. breviceps and K. sima, driven by d

173 hat such stratification applies to the human gut microbiome, in the form of distinct community compos

174 into germ-free SAMP and the presence of the gut microbiome induced IL-33, subsequent eosinophil infi

175 more than a week in vitro and to analyze how gut microbiome, inflammatory cells, and peristalsis-asso

176 ich integrates unique information about host-gut microbiome interactions, gastrointestinal functional

177 evelopment of IBS include alterations in the gut microbiome, intestinal permeability, gut immune func

178 f intra-species copy-number variation in the gut microbiome, introducing a rigorous computational pip

179 The gut microbiome is a complex and metabolically active com

180 The human gut microbiome is a dynamic and densely populated microb

181 The gut microbiome is a dynamic system that changes with hos

182 sults support a novel mechanism in which the gut microbiome is a target of stroke-induced systemic al

183 The preterm gut microbiome is able to develop complexity comparable

184 The gut microbiome is affected by multiple factors, includin

185 Altered gut microbiome is associated with systemic inflammation

186 The gut microbiome is comprised of microbes from multiple ki

187 The gut microbiome is established very early in life.

188 Previous studies have demonstrated that the gut microbiome is extremely sensitive to short-term hosp

189 The mouse gut microbiome is functionally similar to its human coun

190 The development of the preterm gut microbiome is important for immediate and longer-ter

191 Evidence suggests that the gut microbiome is involved in the development of cardiov

192 l, and sociocultural exposures on early life gut microbiome is not yet well-characterized, especially

193 The gut microbiome is suggested to play a role in the pathog

194 crobiota; however, the effect of salt on the gut microbiome is unknown.

195 structure and function of the healthy human gut microbiome is unknown.

196 The gut microbiome is widely studied by fecal sampling, but

197 The effect of gut microbiome leakage on CD4 T cells is currently unkno

198 uox induction, leading to an increase of the gut microbiome load.

199 s in rodents suggest that alterations in the gut microbiome may contribute to amyloid deposition, yet

200 A dysbiotic gut microbiome may play an important role in the develop

201 that the resveratrol-mediated changes in the gut microbiome may play an important role in the mechani

202 Our studies suggest that the gut microbiome may play an important role in the variati

203 To determine whether the gut microbiome may predict responses to IBD therapy, we

204 ence to date suggests that the airway and/or gut microbiome may represent fertile targets for prevent

205 This study reveals the gut microbiome-mediated diabetogenic nature of organopho

206 nction in vivo results in alterations in the gut microbiome, metabolome and immune responses.

207 y, we identify 21 fosmid clones from a human gut microbiome metagenomic library that, when expressed

208 f this technique applied to conjunctival and gut microbiome metagenomics sequencing results.

209 Preclinical mouse models suggest that the gut microbiome modulates tumor response to checkpoint bl

210 Our analyses revealed that the gut microbiome of AD participants has decreased microbia

211 lk associated microbes were increased in the gut microbiome of breastfed infants compared to formula-

212 definitively decreases the diversity of the gut microbiome of children in an antibiotic-naive commun

213 l species and functional genes absent in the gut microbiome of individual humans can be reestablished

214 Here we examined the oral and gut microbiome of melanoma patients undergoing anti-prog

215 omic and predicted functional changes in the gut microbiome of obese mice.

216 the diversity and composition of the patient gut microbiome of responders versus nonresponders.

217 orted decreased fatty acid metabolism in the gut microbiome of subjects whose milk allergy resolved (

218 t of Clostridia and Firmicutes in the infant gut microbiome of subjects whose milk allergy resolved.

219 The recent characterization of the gut microbiome of traditional rural and foraging societi

220 ses disease and drug signatures in the human gut microbiome of type 2 diabetes mellitus (T2D).

221 Furthermore, the gut microbiome of WT mice shifted toward that of the IL-

222 obacillus rhamnosus was able to modulate the gut microbiome of zebrafish larvae, elevating the abunda

223 Deep sequencing of the gut microbiomes of 1135 participants from a Dutch popula

224 Gut microbiomes of adult honey bees (Apis mellifera) inc

225 cal discriminant analysis suggested that the gut microbiomes of autoantibody-positive individuals and

226 pite observing replicable differences in the gut microbiomes of flies maintained on different diets,

227 Mammals host gut microbiomes of immense physiological consequence, bu

228 ntibiotic resistance protein families in the gut microbiomes of individuals from the United States, C

229 ntibody presence, and HLA indicated that the gut microbiomes of seropositive subjects differed from t

230 ) sperm whales were used to characterize the gut microbiomes of two closely-related species with simi

231 Recent studies suggest that gut microbiomes of urban-industrialized societies are di

232 g and quantitative PCR, we characterized the gut microbiomes of wild leaf-feeding caterpillars in the

233 Understanding the importance of the gut microbiome on modulation of host health has become a

234 umented unique metagenomic features of their gut microbiome, our findings on the Hadza metabolome len

235 eport that the composition of the early-life gut microbiome, particularly those species producing lip

236 crobiome-gut-brain axis, it is possible that gut microbiome perturbation may also contribute to diazi

237 sess whether the observed alterations in the gut microbiome play a role in, or are a consequence of,

238 Gut microbiomes play crucial roles in animal health, and

239 The gut microbiome plays a central role in inflammatory bowe

240 The gut microbiome plays a key role in human health, and alt

241 rch over the past few years reveals that the gut microbiome plays a role in basic neurogenerative pro

242 The gut microbiome plays an important role in immune functio

243 Although the gut microbiome plays important roles in host physiology,

244 and signaling pathways involving uric acid, gut microbiome products, and so-called uremic toxins acc

245 onstrate OAT3 involvement in the movement of gut microbiome products, key metabolites, and signaling

246 to investigate interindividual variation in gut microbiome profiles.

247 The gut microbiome proved to be a key driver of EC metabolis

248 Nutrition and the gut microbiome regulate many systems, including the immu

249 Gut microbiome research has been revolutionized by high-

250 Additionally, select gut microbiome residents in ESR1 KO males, such as Lachn

251 Mounting evidence indicates that the gut microbiome responds to diet, antibiotics, and other

252 Colonization of the fetal and infant gut microbiome results in dynamic changes in diversity,

253 ain-level bacterial diversity within hominid gut microbiomes revealed that clades of Bacteroidaceae a

254 datasets reveals clear signatures of the T2D gut microbiome, revealing new phylogenetic and functiona

255 The gut microbiome's responses to antibiotics and its potent

256 Increasing appreciation of the gut microbiome's role in health motivates understanding

257 extend previous work on storage methods for gut microbiome samples by comparing immediate freezing,

258 species and, in large numbers, in all human gut microbiome samples.

259 treatment, we report a unified signature of gut microbiome shifts in T2D with a depletion of butyrat

260 The gut microbiome stimulates the expression of mosGCTLs, wh

261 Dietary lipid content shifted the gut microbiome structure.

262 tions that could arise from manipulating the gut microbiome structure.

263 which plays an important role in maintaining gut microbiome structure/function and thereby contribute

264 adoption will improve comparability of human gut microbiome studies and facilitate meta-analyses.

265 ovide opportunity to conduct metabonomic and gut microbiome studies as explorative and mechanistic re

266 se, which includes 28 published case-control gut microbiome studies spanning ten diseases.

267 g technologies and their potential impact on gut microbiome studies.

268 searchers in experimental design choices for gut microbiome studies.

269 gut microbiota, thereby opening the way for gut microbiome-targeted therapeutics aimed at reducing t

270 ic analyses of genetic polymorphisms and the gut microbiome that may be associated with clinical resp

271 nts in the human genome and dysbiosis of the gut microbiome, though unifying principles for these fin

272 sized that sleep restriction may perturb the gut microbiome to contribute to a disease state.

273 port the potential of therapies altering the gut microbiome to control body mass, triglycerides, and

274 owing recognition of the significance of the gut microbiome to human health, and the association betw

275 Emerging evidence has linked the gut microbiome to human obesity.

276 ew the evidence linking perturbations of the gut microbiome to pancreatic autoimmunity.

277 hesized that NPC1L1 deficiency may alter the gut microbiome to reduce stool output.

278 t captivity has a parallel effect on the NHP gut microbiome to that of Westernization in humans.

279 el therapeutic interventions targeted at the gut microbiome to treat inflammation-associated sickness

280 ey metabolites and signaling molecules (e.g. gut microbiome-to-intestine-to-blood-to-liver-to-kidney-

281 with our intestinal counterpart, pushing the gut microbiome toward a dysbiotic layout, where microbio

282 help guide therapies that will redirect the gut microbiome towards a healthy state and maintain remi

283 Here, we present an analysis of a human gut microbiome using TruSeq synthetic long reads combine

284 To further explore the gut microbiome variation in human populations, here we c

285 Existing studies characterizing gut microbiome variation in the United States suffer fro

286 Gut microbiome was profiled by 16s rRNA sequencing and m

287 Diversity of the gut microbiome was significantly lower in the treated gr

288 Manipulation of the diet, and hence the gut microbiome, was reported to result in immediate asso

289 In particular, changes in the gut microbiome were characterized by a decreased relativ

290 Codes based on the gut microbiome were exceptionally stable and pinpointed

291 cific taxonomic compositions of the oral and gut microbiomes were different, the community types obse

292 Copepod gut microbiomes were investigated quarterly over two yea

293 te a highly specialized diet, koala oral and gut microbiomes were similar in composition to the micro

294 The mammal gut microbiome, which includes host microbes and their r

295 Like the internal gut microbiome, which is increasingly recognized as an i

296 Suppression of gut microbiome with broad-spectrum antibiotics decreases

297 lth, and the association between a perturbed gut microbiome with human diseases has been established.

298 Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosacc

299 nimals (fish and crustaceans), harbor unique gut microbiomes with surprising parallels in functional

300 c resistance as a core function in the human gut microbiome, with tetracycline-resistant ribosomal pr