ライフサイエンスコーパス: gut microbiota

1 mers drives microbial diversity in the human gut microbiota.

2 nt intestinal inflammation by regulating the gut microbiota.

3 elationship between host diet, fattening and gut microbiota.

4 immunity shapes the structure and density of gut microbiota.

5 igned to evaluate the effects of LCSs on the gut microbiota.

6 e infant and shape the composition of normal gut microbiota.

7 c fatty liver disease (NAFLD) is affected by gut microbiota.

8 y the organophosphate-degrading potential of gut microbiota.

9 ble to intervene in obesity by targeting the gut microbiota.

10 ote their replication in the presence of the gut microbiota.

11 alopathy may not be related to alteration in gut microbiota.

12 rld microbial communities, such as the human gut microbiota.

13 MRL/lpr mice by changing the composition of gut microbiota.

14 l transmission was the main force regulating gut microbiota.

15 ral chronic diseases associated with altered gut microbiota.

16 ors, activity levels, and composition of the gut microbiota.

17 cessed foods, which alter the composition of gut microbiota.

18 sorbed antibiotic that is used to change the gut microbiota.

19 of bacteria collectively referred to as the gut microbiota.

20 d secondary bile acids as well as changes in gut microbiota.

21 ence of antibiotic-mediated dysbiosis of the gut microbiota.

22 ria that are referred to collectively as the gut microbiota.

23 ides thetaiotaomicron, a member of the human gut microbiota.

24 al health and performance through modulating gut microbiota.

25 s are major nutrients available to the human gut microbiota.

26 and abundances of various bacterial taxa in gut microbiota.

27 ritionally complete diet in the absence of a gut microbiota.

28 srupting the structural configuration of the gut microbiota.

29 15:0/C17:0 levels were not influenced by the gut-microbiota.

30 BACKGROUND & AIMS: The gut microbiota affects host lipid and glucose metabolism

31 Thus, we demonstrate a defensive role of the gut microbiota against Listeria monocytogenes infection

32 docannabinoid activity can induce changes in gut microbiota and anti-inflammatory state in adipose ti

33 ve disease removed harmful bacteria from the gut microbiota and attenuated SLE-like disease in lupus-

34 bjected to morphological analysis as well as gut microbiota and bile acid profiling.

35 le antibiotic vancomycin, which reshaped the gut microbiota and changed microbial functional pathways

36 relationships between the composition of the gut microbiota and circulating metabolites and provides

37 tudy to demonstrate associations between the gut microbiota and cognition in human infants.

38 Both stress and high fat diet can alter the gut microbiota and contribute to obesity.

39 s, as a critical factor that is regulated by gut microbiota and determines thrombus growth in Tlr2(-/

40 by the host for diet-induced changes of the gut microbiota and energy metabolism.

41 k secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonizati

42 We identify novel associations between gut microbiota and fasting serum levels of a number of m

43 moted systemic changes via regulation of the gut microbiota and gene expression in intestinal tract.

44 a suggest that altered communication between gut microbiota and host systems could participate in dis

45 genic fiber, on the composition of the human gut microbiota and human metabolism.

46 rasite visceralization, indicating that both gut microbiota and IL-1beta are important for the establ

47 Accordingly, both the gut microbiota and immune system are implicated in the e

48 n life, leads to long-lasting changes in the gut microbiota and immune system of mice.

49 s that is accompanied by distinct changes in gut microbiota and increased heat production.

50 Nopal modified gut microbiota and increased intestinal occludin-1 in th

51 uction of oxidative stress in preserving the gut microbiota and its ability to prevent inflammation.

52 Knowledge of the gut microbiota and its constituent actors is changing th

53 lation, thereby affecting the composition of gut microbiota and its metabolites.

54 exhibited changes in the composition of the gut microbiota and long-term treatment with antibiotics

55 interrelationships between obesity, stress, gut microbiota and mood disorders, obesity was induced i

56 arthropod antibacterial protein to alter the gut microbiota and more effectively colonize the vector.

57 stablishing a strong association between the gut microbiota and obesity in humans, a causal relations

58 We examined the impact of IS drugs on gut microbiota and on the expression of ileal antimicrob

59 ween particular bacteria from the indigenous gut microbiota and phenotypes relevant to ASD raise the

60 lic consequences of obesity by modifying the gut microbiota and preventing metabolic endotoxemia in r

61 odulates the composition of lumenal-residing gut microbiota and reduces weaning-related gastrointesti

62 nce of antimicrobial resistance genes in the gut microbiota and the administration of antibiotic feed

63 Communication pathways between gut microbiota and the central nervous system could incl

64 Causality between certain gut microbiota and the development of allergic asthma ha

65 However, the clear connection between gut microbiota and the eCB system in the regulation of e

66 Gut microbiota and the immune system interact to maintai

67 th the short-chain fatty acid acetate on the gut microbiota and the prevention of cardiovascular dise

68 me of the important biomolecules produced by gut microbiota and the role that they may play in mainta

69 his effect is associated with alterations in gut microbiota and their metabolites.

70 food and prebiotic for its ability to modify gut microbiota and to reduce metabolic endotoxemia and o

71 nisms inhabiting the gastrointestinal tract (gut microbiota) and their impact on host health and phys

72 hormonal imbalances, metabolic disturbances, gut microbiota, and cancer.

73 ic low-grade, systemic inflammation, altered gut microbiota, and gut barrier disruption.

74 Because HMOs, gut microbiota, and infant health are interrelated, the

75 ed by fermentation in the large intestine by gut microbiota, and its synthetic derivative, the N-(1-c

76 (RGs) on immune and inflammatory responses, gut microbiota, and microbial products in healthy adults

77 finitive link between host fattening and the gut microbiota, and suggest the squirrels may possess a

78 Gut microbiota are linked to chronic inflammation and ca

79 vealed that Clostridia added to mouse infant gut microbiota are sufficient to limit colonization of p

80 Increasing evidence implicates the gut microbiota as a key regulator of brain and behavior,

81 garding means of therapeutic manipulation of gut microbiota as a novel treatment option for mental he

82 In conclusion, drug discovery targeting the gut microbiota as well as the characterization of microb

83 Changes in the composition of gut microbiota associated with disease, referred to as d

84 might reflect a suboptimal implementation of gut microbiota at specific developmental stages in infan

85 study, we investigated the role of the liver-gut microbiota axis in underpinning the hepatotoxicity o

86 e activity of enzymes derived from the human gut microbiota bacterium Bacteroides thetaiotaomicron, w

87 -dependent concomitant relationships between gut microbiota, BAs, and metabolic diseases in both gend

88 ncover distinct male and female profiles for gut microbiota, BAs, and microRNAs that may contribute t

89 Changes in gut microbiota between IBD and control groups were not a

90 ints to a strong association between sex and gut microbiota, bile acids (BAs), and gastrointestinal c

91 in the stress hormone corticosterone affect gut microbiota by experimentally inhibiting corticostero

92 Thus, targeting of gut microbiota by innovative probiotics, antibiotics, an

93 re-curated interspecies network of the human gut microbiota, called NJS16.

94 ry response, suggesting that manipulation of gut microbiota can be a powerful tool to modulate the co

95 Recent studies revealed that gut microbiota can elicit a variety of effects on the ho

96 ogy; recent studies show that changes in the gut microbiota can modulate gastrointestinal physiology,

97 rmula with specific prebiotics modulated the gut microbiota closer to that of breast-fed infants.

98 role of fat content in the diet in altering gut microbiota community by shifting phylotype compositi

99 , little is known about the consequences for gut microbiota composition and metabolic activity and fo

100 inflammation, which correlates with altered gut microbiota composition and metabolic syndrome, both

101 We further investigate the gut microbiota composition and microbiota-metabolite rel

102 nt with a broad spectrum antibiotic modifies gut microbiota composition and promotes anti-inflammator

103 We previously showed differences in mucus gut microbiota composition preceded colitis-induced infl

104 Thus, ultrafine particles ingestion alters gut microbiota composition, accompanied by increased ath

105 trations and serum vitamin K concentrations, gut microbiota composition, and inflammation.Fecal and s

106 We also found that CB0313.1 modulated gut microbiota composition, characterized by a decreased

107 In addition to alterations in gut microbiota composition, the metabolic potential of g

108 w-grade inflammation and specific changes in gut microbiota composition.

109 cesses within the gut, profoundly influences gut microbiota composition.

110 pear highly variable and are associated with gut microbiota composition.

111 ) reduce gastric acid secretion and modulate gut microbiota composition.

112 in both the intestine and plasma via altered gut microbiota composition.

113 Each geographic locale displayed a unique gut-microbiota composition that could not be fully expla

114 D together with an HFD-induced alteration in gut microbiota contributes to the pathophysiology of the

115 ansplant, confirming that an IL-17-sensitive gut microbiota controls susceptibility to acute GVHD.

116 Homeostasis of the gut microbiota critically influences host health and agi

117 We measured body composition across time and gut microbiota density, diversity and function prior to

118 asma trimethylamine N-oxide (TMAO) levels, a gut microbiota-dependent metabolite associated with coro

119 -) offspring that had received the perturbed gut microbiota developed markedly increased colitis.

120 Moreover, SIRT1 iKO mice with defective gut microbiota developed more severe colitis than contro

121 Although a reduced gut microbiota diversity and low mucosal total IgA level

122 Additionally, we found no differences in gut microbiota diversity or short chain fatty acid produ

123 rter mice, we demonstrate that alteration of gut microbiota during cohousing experiments or treatment

124 Yet, the causal role of the gut microbiota during host aging is largely unexplored.

125 An aberrant IgA responsiveness to the gut microbiota during infancy precedes asthma and allerg

126 WD) (35% kcal from fat) for 6 weeks leads to gut microbiota dysbiosis associated with altered bacteri

127 Gut microbiota dysbiosis was investigated by fecal lipop

128 Gut microbiota dysbiosis, which occurs in response to HF

129 The human gut microbiota ferments dietary non-digestible carbohydr

130 Changes in gut microbiota following CB0313.1 treatment were associa

131 base supporting therapeutic targeting of the gut microbiota for brain-gut axis disorders, opening new

132 Vertebrate gut microbiota form a key component of immunity and a dy

133 Mother's HMO composition and infant gut microbiota from 33 Gambian mother/infant pairs at 4,

134 Gut microbiota from cirrhosis patients and controls show

135 An accumulating body of evidence shows that gut microbiota fulfill an important role in health and d

136 Studies showed that manipulation of gut microbiota (GM) composition through the treatment of

137 limited studies in understanding the role of gut microbiota (GM) in viral-associated diarrhea.

138 Gut microbiota has a proven role in regulating multiple

139 These findings indicate that the bee gut microbiota has basic roles similar to those found in

140 iota composition, the metabolic potential of gut microbiota has been identified as a contributing fac

141 The gut microbiota has been implicated in the development of

142 The gut microbiota has been linked to cardiovascular disease

143 hat antibiotic exposure shaping the maternal gut microbiota has effects that extend to the offspring,

144 Since social transmission of gut microbiota has the potential to enhance immunity, mi

145 The results suggested to SRF that gut microbiota have a causal role in carbohydrate-induce

146 The gut microbiota have been linked with the development of

147 th allergy development, IgA responses to the gut microbiota have not yet been studied.

148 cant interest in recent years has focused on gut microbiota-host interaction because accumulating evi

149 y provides a foundation for investigation of gut microbiota-host mutualism, highlighting key players

150 ifidobacteria are important members of human gut microbiota; however, quantitative data on their earl

151 Diabetes has a significant impact on the gut microbiota; however, studies in the oral cavity have

152 Induction of TH17 cells depends on gut microbiota; however, the effect of salt on the gut m

153 e molecular underpinnings defining commensal gut microbiota immunomodulatory actions on physiologic b

154 t early-life endocrine, as well as potential gut microbiota impacts on brain reward circuitry.

155 ability of prebiotics to specifically modify gut microbiota in children with overweight/obesity or re

156 Gut microbiota in cirrhosis differ from healthy persons

157 ss-talk would help elucidate the role of our gut microbiota in health and disease.

158 Development of the gut microbiota in infancy is important in maturation of

159 Involvement of gut microbiota in lung diseases by the gut-lung axis has

160 f intestinal tissues, colitis induction, and gut microbiota in mice with intestinal epithelial disrup

161 is review, we discuss emerging roles for the gut microbiota in modulating host social and communicati

162 a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheime

163 We will also discuss the roles of gut microbiota in normal physiology and the potential of

164 iological variable in studies on the role of gut microbiota in obesity-related mood disorders.

165 ain axis demonstrate a critical role for the gut microbiota in orchestrating brain development and be

166 ation experiments confirm the involvement of gut microbiota in organophosphate-induced glucose intole

167 We aimed to understand the role of gut microbiota in organophosphate-induced hyperglycemia

168 We studied the composition of gut microbiota in patients with cirrhosis and assessed t

169 The evidence on the role of gut microbiota in post-infectious irritable bowel syndro

170 vidence has revealed the pivotal role of the gut microbiota in shaping the immune system.

171 We analyzed bacterial and eukaryotic gut microbiota in stool samples collected at 3 months of

172 siological activities, and the importance of gut microbiota in supplying micronutrients to animals.

173 The influence of the gut microbiota in the differential effects of sucrose an

174 dence into a model describing a role for the gut microbiota in the maintenance of inflammation and im

175 acid disturbances, and altered responses to gut microbiota in the pathogenesis of Trim28(hep-/-) -as

176 the importance of bacteria, particularly the gut microbiota, in HCT outcome and in GVHD development.

177 ontributing to the assembly and diversity of gut microbiotas include chance events, host-based select

178 that NLRP3(R258W)-induced remodelling of the gut microbiota, induces local Tregs to maintain homeosta

179 th cellulose, a nonfermentable fiber, on the gut microbiota, inflammatory markers, and survival in tw

180 polarization.Emerging evidence suggests that gut microbiota influences immune function in the brain a

181 n gastrointestinal tract, referred to as the gut microbiota, influences host physiology and immunity.

182 Transfer of antibiotic-modified gut microbiota inhibits CS, but this response can be res

183 ecially hinders our understanding of how the gut microbiota interact with the intestinal space, since

184 Metagenomic analysis showed differences in gut microbiota involved in BA metabolism between normal

185 The establishment of the infant gut microbiota is a highly dynamic process dependent on

186 The gut microbiota is an important contributor to human heal

187 The human gut microbiota is an important reservoir of antibiotic r

188 Notably, the gut microbiota is distinct at birth and does not establi

189 The gut microbiota is implicated in numerous aspects of heal

190 Knowledge of the spatial organization of the gut microbiota is important for understanding the physic

191 iled understanding of SCFA metabolism by the gut microbiota is necessary to underpin effective strate

192 n the composition and function of the infant gut microbiota is not well defined.We sought to determin

193 These findings indicate that the gut microbiota is required for the normal visceral pain

194 tibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adapt

195 The human gut microbiota makes key contributions to the metabolism

196 Gut microbiota may be altered in patients with cirrhosis

197 The composition of gut microbiota may change in IBD affected individuals, b

198 g ACVD as well as other related diseases.The gut microbiota may play a role in cardiovascular disease

199 gical triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects jo

200 iew key findings on the interactions between gut microbiota members and the immune system.

201 rce of dietary proteins act as regulators of gut microbiota metabolite production and host gene expre

202 Further, some of the predicted pomegranate gut microbiota metabolites modulated (14)C-D-glucose and

203 auxotrophic mutants and is then applied to a gut microbiota model consisting of nine species, with re

204 The gut microbiota modulate host biology in numerous ways, b

205 We studied the gut microbiota of 138 infants at increased risk of aller

206 the relationship between social dynamics and gut microbiota of a group-living cooperative species of

207 Different factors may modulate the gut microbiota of animals.

208 inter-organ signaling and interplay with the gut microbiota of bile acids and their receptors in meta

209 Gut microbiota of breastfed compared with nonbreastfed i

210 of diet on pre-hibernation fattening and the gut microbiota of captive arctic ground squirrels (Uroci

211 Given that pollutants can alter the gut microbiota of hosts, which in turn can affect their

212 The gut microbiota of individuals are dominated by different

213 als in different locations may influence the gut microbiota of infants.

214 In females, stress caused the gut microbiota of lean mice to more closely resemble tha

215 flies with constitutive immunity defined the gut microbiota of their cohabitants.

216 ing immune system and the not-yet-stabilized gut microbiota of young children to facilitate its persi

217 onal variation (i.e., beta-diversity) in the gut microbiotas of 136 pairs of wild mammalian species l

218 phere, the compositional overlap between the gut microbiotas of allopatric mammalian populations deca

219 dispersal promote beta-diversity between the gut microbiotas of mammalian species.

220 e that compositional differences between the gut microbiotas of mammalian taxa are generated and main

221 Comparing the gut microbiotas of sympatric and allopatric mammalian po

222 ects of different dietary components and the gut microbiota on mice with and without DSS-induced coli

223 dels demonstrating the essential role of the gut microbiota on the development and function of the ho

224 dentify two dynamic regimes within the human gut microbiota: one likely driven by external environmen

225 iminution correlates with alterations in the gut microbiota, particularly enrichment of Propionibacte

226 Gut microbiota play an important role in regulating the

227 The symbiotic gut microbiota play pivotal roles in host physiology and

228 The gut microbiota plays a chief role in vitamin production.

229 lly short-lived vertebrate, we show that the gut microbiota plays a key role in modulating vertebrate

230 to host-microbe symbiosis in adulthood, the gut microbiota plays a vital role in our development and

231 Gut microbiota plays an important role in host health an

232 that high consumption of fiber modified the gut microbiota populations and increased the abundance o

233 The complexity and dynamism of the gut microbiota pose considerable challenges for quantita

234 The gut microbiota possesses diverse metabolic activities, b

235 The human gut microbiota produces dozens of metabolites that accum

236 Finally, the gut microbiota produces molecules that act on enteric ne

237 In conclusion, we show that depletion of gut microbiota profoundly protects against renal I/R inj

238 trointestinal tract, collectively called the gut microbiota, profoundly influences many aspects of ho

239 We found that gut microbiota promotes the development of chemotherapy-

240 Here we show that the gut microbiota promotes weight gain of both whole body a

241 Molecular factors from the gut microbiota provide the host with the right metabolic

242 a-sample duality in the data to show how the gut microbiota recovers following this perturbation.

243 nging C difficile suppression and supporting gut microbiota recovery.

244 Despite knowledge the gut microbiota regulates bone mass, mechanisms governing

245 The gut microbiota regulates T cell functions throughout the

246 Science, Wang et al. (2017) reveal that the gut microbiota regulates the expression of circadian-clo

247 We investigate gut microbiota relationships with a variety of factors t

248 source for future studies to understand host-gut microbiota relationships.

249 AgNC treated groups had select reductions in gut microbiota relative to controls.

250 Ensuring that gut microbiota respond consistently to prescribed dietar

251 Rather, HFD decimates gut microbiota, resulting in loss of enterocyte prolifer

252 Studies of the heritability of gut microbiotas reveal a subset of microbes whose abunda

253 er-Bone Axis intriguingly implies the normal gut microbiota's osteoimmunomodulatory actions are partl

254 s bone mass, mechanisms governing the normal gut microbiota's osteoimmunomodulatory effects on skelet

255 frequency and has modest positive effects on gut microbiota, SCFAs, effector memory T cells, and the

256 tis model, we show that a constituent of the gut microbiota, segmented filamentous bacteria (SFB), di

257 AgNPs, cube (AgNC) and sphere (AgNS) affects gut microbiota, select behaviors, and induces histopatho

258 in Ruminococcus and Dorea were identified as gut microbiota signatures of NAFL onset and NAFL-NASH pr

259 We conclude that alterations of the gut microbiota, specifically a depletion of Clostridia,

260 Perturbation of the gut microbiota structure by environmental and genetic fa

261 polysaccharides play extensive roles in host-gut microbiota symbiosis beyond dietary polysaccharide d

262 quently associated with an alteration of the gut microbiota, termed dysbiosis, which is characterized

263 Bacteroides spp. are members of the human gut microbiota that confer myriad benefits on their host

264 A diet high in fiber led to changes in the gut microbiota that played a protective role in the deve

265 bution of one of the main metabolites of the gut microbiota, the short-chain fatty acid acetate.

266 contributions of these fatty acids from the gut-microbiota, the diet, and novel endogenous biosynthe

267 evaluate potential influences on the infant gut microbiota through a longitudinal study on cohorts o

268 g cells (pAPCs) recognize and respond to the gut microbiota through multiple pattern-recognition rece

269 to explain its widespread occurrence in the gut microbiota through the ability to transmit between h

270 Here, we investigated the contribution of gut microbiota to chemoresistance in patients with color

271 nding of the regulation of both the lung and gut microbiota to derive appropriate targets for prevent

272 However, the contributions of gut microbiota to host physiology have yet to be investi

273 ce elements such as copper and zinc, altered gut microbiota to more pathogenic bacteria, increased in

274 her assess evidence linking dysbiosis of the gut microbiota to neurobehavioral diseases, such as auti

275 Emerging evidence links perturbations in the gut microbiota to neurological disease, including diseas

276 The contribution of the gut microbiota to the metabolism of cholesterol is not w

277 tribution of resident gut microorganisms-the gut microbiota-to human health has surged.

278 The human gut microbiota use complex carbohydrates as major nutrie

279 In this study, we profile gut microbiota using 16S rRNA gene sequencing in 531 wel

280 The human gut microbiota utilizes complex carbohydrates as major n

281 uring the experiment, the composition of the gut microbiota was analyzed by 16 S rRNA gene high-throu

282 The composition of gut microbiota was assessed by sequencing the 16S rRNA g

283 The gut microbiota was highly dynamic in HCT recipients, wit

284 ts and compositional differences among their gut microbiotas was independent of dietary and phylogene

285 e T1D is associated with modification of the gut microbiota, we investigated MAIT cells in this patho

286 , appetite, markers of glycemic control, and gut microbiota were measured at 2 and 8 wk.By design, bo

287 Natural gut microbiota were modified by oral treatment with enro

288 al or cesarean section) is thought to affect gut microbiota, which in turn may affect psychological w

289 triglycerides and cholesterol by influencing gut microbiota, which in turn modulate intestinal gene e

290 IAFGP thereby perturbs the tick gut microbiota, which influences the integrity of the pe

291 nate antimicrobial defenses and disrupts the gut microbiota, which leads to overgrowth of indigenous

292 Food deprivation also challenges the gut microbiota, which relies heavily on host diet for me

293 is of a controlled perturbation of the human gut microbiota with a new level of resolution.

294 To study this concept, we depleted gut microbiota with broad-spectrum antibiotics and perfo

295 obiota analysis revealed a severely depleted gut microbiota with concomitant opportunistic pathogen o

296 cancer; this is mainly through a remodelled gut microbiota with enhanced anti-inflammatory capacity

297 Red-bellied lemurs were found to have gut microbiota with slight temporal fluctuations and str

298 We sought to test whether the change of gut microbiota with the broad spectrum antibiotic enrofl

299 ractions occurring between parasites and the gut microbiota, with a profound impact on both host immu

300 Given geographic differences in human gut microbiota worldwide, we studied the effects of gut