ライフサイエンスコーパス: gyri

1 tcentral/superior parietal and supramarginal gyri).

2 boundary of the Middle and Superior Temporal Gyri.

3 regions, predominantly in the middle frontal gyri.

4 left superior, middle, and inferior temporal gyri.

5 le temporal, middle occipital and precentral gyri.

6 ards the superior temporal and supramarginal gyri.

7 the medial and ventromedial superior frontal gyri.

8 ntified in the inferior frontal and fusiform gyri.

9 merous (poly) and noticeably smaller (micro) gyri.

10 tion of the left inferior and middle frontal gyri.

11 ecific for areas in the lingual and fusiform gyri.

12 tal, anterior cingulate, and parahippocampal gyri.

13 right mid-frontal, and left inferior frontal gyri.

14 right superior frontal and inferior parietal gyri.

15 ter growth speed could consistently engender gyri.

16 mporal cortices, including superior temporal gyri.

17 t (P=.003) and right (P=.012) middle frontal gyri.

18 al regions, cingulate and lateral precentral gyri.

19 panied by folding of the cortical sheet into gyri.

20 ferior occipital and right inferior temporal gyri.

21 s cortical size and induces folds resembling gyri.

22 lear speech activated both anterior fusiform gyri.

23 l, superior and middle temporal, and lingual gyri.

24 oral cortex, and inferior and middle frontal gyri.

25 uctuations between left and right precentral gyri.

26 with the common feature of abnormal cerebral gyri.

27 and superior, middle, and inferior temporal gyri.

28 frontal gyri and the bilateral supramarginal gyri.

29 that links the cingulate and parahippocampal gyri.

30 in both the anterior and posterior cingulate gyri.

31 ion of the left middle and inferior temporal gyri.

32 ea, including the right lingual and fusiform gyri.

33 l as the supramarginal and superior temporal gyri.

34 l areas, particularly the bilateral fusiform gyri.

35 early cortical thickening was present on the gyri.

36 roup with the bilateral pre- and postcentral gyri.

37 ortical laminae, multiple cortical areas and gyri.

38 were also found within the pre/post-central gyri.

39 egion lying between the fusiform and lingual gyri.

40 t superior frontal and left middle occipital gyri.

41 ior temporal gyrus, and pre- and postcentral gyri.

42 oral cortex to the angular and supramarginal gyri.

43 frontal cortex and the angular and cingulate gyri.

44 al and medial temporal cortex, and cingulate gyri.

45 brain is strongly convoluted into sulci and gyri.

46 also within the middle and inferior frontal gyri.

47 in the left inferior frontal and postcentral gyri.

48 ctivated both the precentral and postcentral gyri.

49 te and both left fusiform and medial frontal gyri.

50 bolism in right superior and middle temporal gyri.

51 on the adjacent superior and middle temporal gyri.

52 anges in the hippocampus and parahippocampal gyri.

53 l and inferior frontal gyri and the temporal gyri.

54 la and dorsal and ventral anterior cingulate gyri (ACG), regions important for attention to and perce

55 e bilateral anterior cingulate/paracingulate gyri (ACG/ApCG), left cerebellum (lobules IV/V and VIII)

56 d left inferior frontal and middle occipital gyri activity and correlated negatively with plasma ghre

57 The gyrI (also called sbmC) gene product inhibits DNA gyrase

58 haracterized by an excessive number of small gyri and abnormal cortical lamination.

59 ctivation in the middle and inferior frontal gyri and anterior cingulate gyrus, in addition to region

60 in inferior prefrontal and superior temporal gyri and cerebellum.

61 ntal lobes, including cingulate and fusiform gyri and cerebellum.

62 Cortical folding, characterized by convex gyri and concave sulci, has an intrinsic relationship to

63 isphere middle temporal and inferior frontal gyri and decreased activity in right inferotemporal cort

64 toencephalography revealed enlarged Heschl's gyri and enhanced right-left hemispheric synchronization

65 children showed reduced volumes of Heschl's gyri and enhanced volumes of the plana temporalia that w

66 2 and 21 of the superior and middle temporal gyri and had significantly higher metabolism in parietal

67 cited activation in the lingual and fusiform gyri and in the Brodmann areas 22 and 38 in superior tem

68 ula, and parahippocampal and middle temporal gyri and in the left inferior frontal and postcentral gy

69 ce of a circuit between left middle temporal gyri and inferior frontal gyrus for both groups.

70 luding the left superior and middle temporal gyri and inferior frontal gyrus, and there was no signif

71 olumes in the left and right middle temporal gyri and left posterior superior temporal gyrus were pre

72 ination; (ii) left superior-/middle-temporal gyri and receptive aphasia; (iii) widespread temporal/fr

73 d GMV in the caudate, thalamus, and fusiform gyri and reduced GMV in the cerebellar vermis in FXS at

74 because VBM analysis includes both cortical gyri and sulci as a single GM region.

75 nduced the formation of prominent, bilateral gyri and sulci in the rostrolateral neocortex.

76 maging revealed only an irregular pattern of gyri and sulci, for which we propose the term tubulinopa

77 oduction of neuroepithelial folds resembling gyri and sulci, which are not normally present in avian

78 in the cortex is coupled to the formation of gyri and sulci.SIGNIFICANCE STATEMENT Abnormal brain mor

79 yrus, posterior middle and superior temporal gyri and superior temporal sulcus, as well as the white

80 ted in premotor cortex, pre- and postcentral gyri and supramarginal gyrus with minimal extension into

81 right inferior and bilateral middle frontal gyri and the bilateral supramarginal gyri.

82 nts in the left inferior and middle temporal gyri and the left middle occipital gyrus (ROI depression

83 cluded the right and left inferior occipital gyri and the right middle occipital gyrus, right inferio

84 ng the superior, medial and inferior frontal gyri and the temporal gyri.

85 ons in the left middle and superior temporal gyri and to the inferior parietal lobe was a predictor o

86 indicate variations in the shape of parietal gyri and white matter microstructural anomalies of the t

87 ved the prefrontal (gyrus rectus and orbital gyri) and then postcentral neocortex and striatum.

88 al gyri, bilateral middle occipital/fusiform gyri, and bilateral cerebella for both the rhyming and m

89 posterior cingulate cortex, parahippocampal gyri, and frontal pole, that exhibited activity uniquely

90 rtex, amygdala, middle and inferior temporal gyri, and fusiform gyrus the most severely damaged.

91 t posterior parahippocampal and mid-fusiform gyri, and in the hippocampal body in healthy young indiv

92 hippocampus and parahippocampal and fusiform gyri, and increasing activation in the posteromedial cor

93 rea (SMA), frontal operculum, middle frontal gyri, and inferior parietal lobule were specifically ass

94 ding right V1 and cuneus, bilateral fusiform gyri, and left parietal cortex.

95 l, right superior and left inferior temporal gyri, and left superior parietal lobule.

96 uperior frontal and right anterior cingulate gyri, and left thalamus.

97 eocortical delineations were done for sulci, gyri, and modified Brodmann areas to link macroscopic an

98 emporal (T = 4.25) and precentral (T = 6.47) gyri, and one right ILF end point, the occipital lobe (T

99 gions in the inferior occipital and fusiform gyri, and perception of eye gaze was mediated more by re

100 ocampus, supramarginal and inferior temporal gyri, and posterior cerebellum, with decreased activity

101 or hippocampus, parahippocampal and fusiform gyri, and predominantly left hemisphere extra-temporal a

102 claustrum, right middle and inferior frontal gyri, and right angular gyrus.

103 gyrus, bilateral middle and inferior frontal gyri, and right precuneus.

104 laterally, right middle and superior frontal gyri, and right visual association cortex (area 18) comp

105 totopically on ventral pre- and post-central gyri, and that partially overlap at individual electrode

106 rtices, anterior cingulate and paracingulate gyri, and the insula.

107 rolateral prefrontal gyri, superior temporal gyri, and the putamen (p < .001).

108 ral orbitofrontal gyrus and inferior frontal gyri, and the rostral anterior cingulate cortex.

109 ions of the cortical surface: the sulci, the gyri, and the straight bank region, which is interposed.

110 network in the superior and middle temporal gyri; and atrophy of anterior components of the face and

111 comparison group in the bilateral precentral gyri, anterior cingulate cortex, and middle and superior

112 ith functional MRI confirm that the fusiform gyri are involved in color and face perception, and show

113 o faces, whereas the parahippocampal/lingual gyri are more responsive to buildings.

114 s have clearly established that the fusiform gyri are preferentially responsive to faces, whereas the

115 ace of the cortex, where normally convoluted gyri are replaced by numerous (poly) and noticeably smal

116 The transverse gyri are thought to be established in utero; our results

117 vation of Broca's area and the supramarginal gyri, areas associated with phonological recoding.

118 efrontal cortex (superior and middle frontal gyri-areas 6 and 9), posterior cingulate (area 31), and

119 unction was observed in the pre/post-central gyri as expected.

120 ate cortex, and middle and superior temporal gyri as well as greater activation relative to both comp

121 thickness of left angular and supramarginal gyri as well as the left lateral occipital cortex.

122 ing, such as the inferior and middle frontal gyri, as well as the supramarginal and superior temporal

123 ed activation in bilateral superior temporal gyri (BA 42 and 22), a region associated with phonologic

124 o increased size in FXS, such as the orbital gyri, basal forebrain, and thalamus, suggests delayed or

125 interest were drawn in pre- and postcentral gyri based on anatomic criteria.

126 , the right inferior and left medial frontal gyri (beta = 0.75 vs. 0.54), and the left thalamus (beta

127 men, right middle occipital/ middle temporal gyri, bilateral cingulate gyrus and right sensorimotor a

128 the frontal lobe (medial and middle frontal gyri, bilateral inferior frontal gyrus), parietal lobe (

129 d activation in left inferior/middle frontal gyri, bilateral medial frontal gyri, bilateral middle oc

130 iddle frontal gyri, bilateral medial frontal gyri, bilateral middle occipital/fusiform gyri, and bila

131 for generate>read in inferior/middle frontal gyri bilaterally (L>R), anterior cingulate, and caudate

132 frontal cortex's superior and middle frontal gyri bilaterally and in the left occipital lobe as a con

133 ral activations within the superior temporal gyri bilaterally and no increased extra-temporal areas o

134 or middle temporal, and inferior postcentral gyri bilaterally, and enlarged superior frontal gyrus, g

135 er fell secondarily on core and intermediate gyri but, overall, was preserved on the outer (upper lev

136 cting both the cingulate and parahippocampal gyri, but also the limbic and visual cortices.

137 Activation of fusiform gyri by faces was strongly affected by attentional condi

138 sylvian fissure and temporal and postcentral gyri, by using magnetic resonance data and a novel surfa

139 a also suggest that the position of cortical gyri can be molecularly specified in mice.

140 ng to inferior frontal and superior temporal gyri, caudate, and other structures is affirmed.

141 tivation in left inferior and middle frontal gyri, caudate, and thalamus.

142 decreased FA in the genu, cingulum cingulate gyri, centrum semiovale, inferior longitudinal fasciculi

143 ions (mostly the middle and inferior frontal gyri, cingulate, and insula) showed significant LR group

144 activation in superior temporal and frontal gyri, cingulate, thalamus, and basal ganglia.

145 also cingulate, paracentral, and precentral gyri, compared with the non-hallucinators.

146 the visual field tends to be represented on gyri (convex folds), whereas the horizontal meridian is

147 the medial frontal, temporal, and cingulate gyri correlated with severity of positive symptoms.

148 Left middle temporal gyri correlated with task accuracy for both groups.

149 posterosuperior, middle temporal and angular gyri corresponding to Wernicke's area.

150 eral prefrontal cortex and superior temporal gyri, deficit regions found consistently in adult studie

151 mplex, the parahippocampal, and the fusiform gyri did not predict target presence, while high-level a

152 ctions into the middle and inferior temporal gyri displayed no hippocampal neuronal loss or mossy fib

153 al cortex, as well as precentral/postcentral gyri during processing of threatening faces predicted gr

154 emporal, supramarginal, and superior frontal gyri during reappraisal were among the best predictors,

155 , bilaterally in the middle frontal/premotor gyri, extending down the medial prefrontal wall to the a

156 for all contacts), (2) the anatomy of insula gyri (for 20 vestibular sites), and (3) the probabilisti

157 We also examined dentate gyri from epileptic human hippocampal surgical specimens

158 initial values and rates of change higher in gyri, frontal and temporal poles, and parietal cortex; a

159 and included the middle and inferior frontal gyri, frontal limbic area, anterior insula, and inferior

160 recentral gyrus, middle and superior frontal gyri, frontal pole, and cingulate gyrus in S-allele carr

161 e, primary visual cortex, superior occipital gyri, fusiform gyri, ventral premotor area, superior par

162 However, the middle and inferior temporal gyri have received little investigation, especially in f

163 ions within the superior and middle temporal gyri, hippocampus, and LIFG were insensitive to the acou

164 percent neuronal commitments in the dentate gyri however, were not significantly different from cont

165 action of AD hippocampal and parahippocampal gyri (HPG), superior and middle temporal gyri (SMTG), an

166 thin the bilateral anterior interior frontal gyri (IFG), left posterior IFG, SMG, and posterior cingu

167 and from U-shaped fibres connecting adjacent gyri; (iii) it arises in extrastriate visual 'associatio

168 e bilateral superior-temporal and precentral gyri immediately following question onset; at the same t

169 the inferior, middle, and superior temporal gyri in 20 patients with first-episode schizophrenia, 20

170 , hippocampus, parahippocampal, and fusiform gyri in 30 of 31 subjects compared with normal eye image

171 The cingulate gyri in 37 subjects with and without early dementia of t

172 n amplitude across the pre- and post-central gyri in a diffuse manner that is not finger-specific.

173 farct of the right angular and supramarginal gyri in a setting of chronic migraine.

174 ey role of listener's left superior temporal gyri in extracting the slow approximately 0.5 Hz modulat

175 me in the right superior and middle temporal gyri in nonrecovered amusic patients compared with nonam

176 ter decreases in superior and medial frontal gyri in participants with hearing loss compared to norma

177 in the left inferior frontal and precentral gyri in subjects who remain well.

178 ly to have multiple or split left transverse gyri in the auditory cortex than nonexpert controls, and

179 ility along the superior and middle temporal gyri in the left hemisphere and in a less-extensive homo

180 en sgACC and the middle and inferior frontal gyri in the MDD group.

181 h cerebral hemispheres except for precentral gyri in the second one.

182 of the core with respect to major sulci and gyri in the superior temporal region varied most in the

183 g the posterior superior and middle temporal gyri, in classical Wernicke's area.

184 comprehension in bilateral superior temporal gyri (including primary auditory cortex), thalamus, and

185 activation in inferior and superior frontal gyri, including dorsolateral prefrontal cortex and ventr

186 onse in medial prefrontal cortex and angular gyri increased linearly with the probability of the curr

187 nset-degree of anomaly of asymmetry for both gyri increased with age at onset in men but not in women

188 activated voxels in the pre- and postcentral gyri induced by active and passive movements was compare

189 n, parahippocampal, lingual, middle temporal gyri, inferior and superior parietal lobules and precune

190 l cortex, right superior and middle temporal gyri, insula, right posterior cingulate cortex, lingual

191 al sulci, amygdala, and the inferior frontal gyri/insula, targets evoked stronger responses than dist

192 ) and the left dorsolateral superior frontal gyri (item-gamma) on permutation test, where the couplin

193 cingulate (cue-alpha) and the left fusiform gyri (item-gamma).

194 iform gyrus (FG) and right inferior temporal gyri (ITG).

195 including dorsal superior and middle frontal gyri, lateral and medial orbitofrontal gyri, right anter

196 We found that within the inferior occipital gyri, lateral fusiform gyri, superior temporal sulci, am

197 sely, participants with larger left Heschl's gyri learned consonantal or tonal contrasts faster than

198 lated happiness network included postcentral gyri, left caudate, right cingulate cortex, right superi

199 ent in the left superior and middle temporal gyri, left inferior parietal region with postcentral gyr

200 left middle and bilateral inferior temporal gyri, left parahippocampal area, left geniculum body, le

201 right inferior temporal and middle occipital gyri, left precentral gyrus, bilateral opercular part of

202 GyrI-like proteins are widely distributed in prokaryotes

203 gs suggest that the evolutionarily conserved GyrI-like proteins confer cellular protection against di

204 Convoluted cortical gyri-like structures characterize the mushroom body caly

205 ithin which the middle and inferior temporal gyri may play a key role.

206 temporal lobe (superior and middle temporal gyri) may be specific to schizophrenia, whereas smaller

207 re obtained in superior and inferior frontal gyri, medial and lateral orbitofrontal cortex, and parah

208 in the middle frontal and inferior temporal gyri (MFG and ITG) and resistant (cerebellum) to classic

209 cortex, primarily within the middle frontal gyri (MFG).

210 ferences in the cuneus, lingual and fusiform gyri, middle occipital lobe, inferior parietal lobule, a

211 ppocampal gyrus, inferior and middle frontal gyri, middle temporal gyrus, and lingual gyrus.

212 ions of the left and right superior temporal gyri (mSTG).

213 In all 35 gyri, neuron number/mm2-column: (1) initially declines (

214 In the insula, precentral and postcentral gyri NTDE signals were greater, and PTDE-related functio

215 surface area and folds resembling sulci and gyri of higher mammals.

216 d in the medial and posterior orbito-frontal gyri of the frontal lobe.

217 y in the lateral and anterior orbito-frontal gyri of the frontal lobe.

218 parietal gyrus and supramarginal and angular gyri of the inferior parietal lobe), right precuneus, an

219 middle frontal, middle temporal, and angular gyri of the left hemisphere and the lingual and inferior

220 g-form PDE4D isoforms into bilateral dentate gyri of the mouse hippocampus downregulated PDE4D4 and P

221 ume and asymmetry measures of the individual gyri of the parietal lobe by means of magnetic resonance

222 sphere and the lingual and inferior temporal gyri of the right hemisphere and regression of participa

223 reversed in the parahippocampal and fusiform gyri of the schizophrenic patients.

224 tor proliferation in the hippocampal dentate gyri of wild-type adult mouse brains.

225 mes of both the parahippocampal and fusiform gyri on the left side.

226 d by a four layered structure lacking normal gyri or sulci.

227 the superior frontal and anterior cingulate gyri (P > 0.01).

228 and FA values in the cerebellum and fusiform gyri (P < .05).

229 nt of the prefrontal, temporal, and parietal gyri (P < .05, false discovery rate corrected).

230 nding into the bilateral posterior cingulate gyri (P <.001) and left (P=.003) and right (P=.012) midd

231 .001), bilateral superior and middle frontal gyri (P <.001), and left inferior parietal lobe (P=.007)

232 nding into the bilateral posterior cingulate gyri (P <.001), bilateral superior and middle frontal gy

233 ation in precentral (P<.001) and postcentral gyri (P = .03) and the cerebellum (P<.001), although 3 B

234 ddle frontal (P = 0.002) and middle temporal gyri (P = 0.033) and transentorhinal (P = 0.005) and ant

235 ight inferior, middle, and superior temporal gyri (PFWE < 0.05); right temporal pole, anterior hippoc

236 nal connectivity of the bilateral precentral gyri positively correlated with fractional anisotropy va

237 resulted in greater deactivation in fusiform gyri, possibly reflecting greater suppression of visual

238 c nodes of the default mode network (angular gyri, posterior cingulate, and medial prefrontal cortex)

239 basal forebrain, cingulate and paracingulate gyri, posterior supramarginal gyrus, and planum temporal

240 ly engaged the superior frontal and parietal gyri, precentral gyrus, and the caudate.

241 ae, cingulate cortices, pre- and postcentral gyri, precunei, cunei, bilateral putamena, right pallidu

242 activity in the inferior and middle frontal gyri, precuneus, cingulate cortex, caudate, and postcent

243 this relationship at the level of individual gyri provides additional evidence of differences in the

244 h activity in right superior/middle temporal gyri regardless of tissue integrity.

245 s) and lateral (superior and middle temporal gyri) regions of the posterior temporal lobes.

246 sponse in the left angular and supramarginal gyri, regions that play important roles in linguistic pr

247 or cingulate and superior and medial frontal gyri relative to those with hearing loss and tinnitus.

248 icularly the inferior occipital and fusiform gyri, remained selective despite showing only 9%-25% of

249 ough all cortical layers (mm2-column) for 35 gyri (representing about 73% of the human cerebral corte

250 n the core, intermediate and outer penumbral gyri, respectively.

251 erally in the parietal region (supramarginal gyri), right posterior cingulate gyrus, and left occipit

252 ontal gyri, lateral and medial orbitofrontal gyri, right anterior insula, putamen, thalamus, and caud

253 p in the left and right laterodorsal frontal gyri, right medial prefrontal cortex, right superior and

254 re found in left medial and inferior frontal gyri, right precuneus, left inferior parietal lobule, an

255 brain regions, including MT or V5, fusiform gyri, right premotor cortex, and the intraparietal sulci

256 formation of the precentral and postcentral gyri, right superior temporal gyrus, and opercula, which

257 refrontal cortices, and the superior frontal gyri, right ventrolateral prefrontal cortex, the dorsal

258 right inferior, middle, and superior frontal gyri (ROI compensation).

259 vs. 1.48, P < 0.001) and posterior cingulate gyri ROIs (1.63 vs. 1.72, P < 0.001).

260 to the formation of cusped sulci and smooth gyri similar to those in the brain.

261 rietal lobule (SPL), and right supramarginal gyri (SMG).

262 In the superior and middle temporal gyri (SMTG) of AD subjects, the levels of PLCgamma were

263 pal gyri (HPG), superior and middle temporal gyri (SMTG), and inferior parietal lobule (IPL).

264 al (PostCG) and the superior occipital (SOG) gyri, suggesting complex visual processing in this netwo

265 ts noted the cortex is thinner in sulci than gyri, suggesting that development may occur on a fine sc

266 d and consistent by presenting an intriguing gyri-sulci formation comparison.

267 ions are centered near-but distinct from-the gyri/sulci for which they were originally named.

268 bilateral insulae, ventrolateral prefrontal gyri, superior temporal gyri, and the putamen (p < .001)

269 he inferior occipital gyri, lateral fusiform gyri, superior temporal sulci, amygdala, and the inferio

270 ala; superior, middle, and inferior temporal gyri; superior parietal lobe; and posterior cingulate gy

271 ng bilateral STG, precentral and postcentral gyri, supplementary motor area, supramarginal gyrus, pos

272 bilinguals have, on average, larger Heschl's gyri than monolinguals.

273 Mean diffusivity was higher in gyri than sulci and in frontal compared with occipital l

274 ons (ie, supramarginal and superior parietal gyri) that merit further investigation.

275 reas such as the superior and middle frontal gyri, the insula, and the occipital cortex.

276 gulate cortex, the left and right precentral gyri, the left and right anterior temporal cortices, and

277 the superior, middle, and inferior temporal gyri, the left posterior superior temporal gyrus gray ma

278 ior frontal, inferior parietal, and fusiform gyri; the precuneus; and the dorsomedial prefrontal cort

279 strong in the inferior temporal and fusiform gyri, two areas important for object recognition.

280 al cortex, superior occipital gyri, fusiform gyri, ventral premotor area, superior parietal lobule, c

281 pathologies, although precentral/postcentral gyri volume was reduced in comparison with other patholo

282 d significantly less bilateral orbitofrontal gyri volume, higher functional connectivity in the orbit

283 ation in the left and right inferior frontal gyri was determined with respect to the anatomical sub-r

284 rior insula and bilateral anterior cingulate gyri was observed during the processing of fearful faces

285 activity in left inferior and middle frontal gyri was observed when comparing words with partwords an

286 m, insula, and inferior and superior frontal gyri was positively related to the motion speed of dot p

287 FA in the parahippocampal gyri was significantly decreased in patients with sleep

288 forms the boundaries of major orbitofrontal gyri, was classified into three types (Type I, II and II

289 left and right parahippocampal and fusiform gyri were assessed with a stereological point-counting t

290 the superior, inferior, and middle temporal gyri were atrophic, and subjacent white matter was gliot

291 in the left postcentral and middle occipital gyri were found only in older maltreated individuals rel

292 umes of the left and right superior temporal gyri were measured using magnetic resonance imaging obta

293 in both the anterior and posterior cingulate gyri were visualized in the patients with autism spectru

294 vated in the left and right inferior frontal gyri when performing a covert verb generation task.

295 h interactions in medial frontal and lingual gyri, whereas processing of happy faces was associated w

296 Hz to the activity of both superior temporal gyri, whereas the modulations at 4-8 Hz were coupled to

297 eased in width and produced folds resembling gyri, which are not normally present in mouse brains and

298 The pattern of sulci and gyri, while simple, appears very similar to that observe

299 are the right lingual and bilateral fusiform gyri, while the areas specialized for famous stimuli (ir

300 cts including enlarged cerebella and dentate gyri with increased size of neuronal nuclei and somata,