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1                         The effect of the LH/hCG receptor 3' UTRs on luciferase expression was also d
2 vide novel insights into the mechanism of LH/hCG receptor activation.
3  mutations, Asp-556 --> Gly, into the rat LH/hCG receptor and demonstrated that the mutant receptor c
4 bed RNAs corresponding to the full-length LH/hCG receptor, as well as 5'- and 3'-truncated receptor f
5 lization of another constitutively active LH/hCG receptor (aspartic acid 556 to tyrosine) was also gr
6 TSHbeta with the hCG sequence conferred full hCG receptor binding and activation to the hTSH chimera,
7                   Cells transfected with the hCG-receptor construct contained elevated basal levels o
8 ing hormone/human chorionic gonadotropin (LH/hCG) receptor have been shown to cause constitutive acti
9 sence of functional luteinizing hormone (LH)/hCG receptors in human breast cells, prompted us to inve
10 ing hormone/human chorionic gonadotropin (LH/hCG) receptor (LHR) in cultured hypothalamic cells and i
11 report describes the first evidence of an LH/hCG receptor mRNA binding protein, which we term LRBP-1,
12  UTR) of the 6.7 kb transcript, the major LH/hCG receptor mRNA in rat ovary.
13 or involved in the hormonal regulation of LH/hCG receptor mRNA stability in rat ovary.
14 ing hormone/human chorionic gonadotropin (LH/hCG) receptor mRNA stability during hCG-induced receptor
15                                   Second, LH/hCG receptor mRNAs with the long 3' UTR associated with
16 ing hormone/human chorionic gonadotropin (LH/hCG) receptor mRNAs (6.7, 4.4, 2.6, and 1.8 kb) have bee
17 owing characteristics: 1) specificity for LH/hCG receptor open reading frame sequences located betwee
18 orresponding to the open reading frame of LH/hCG receptor or luciferase, plus these constructs with t
19 or down-regulation, we have identified an LH/hCG receptor-specific mRNA binding protein.
20 ntibodies, we use a short oligopeptide as an hCG receptor to bind hCG.
21 with the short (4.4 kb) and long (6.7 kb) LH/hCG receptor transcripts, and measured receptor or lucif
22 the constitutively active D556G and D556Y LH/hCG receptors utilize the arrestin dependent internaliza
23 ing hormone/human chorionic gonadotropin (LH/hCG) receptor, which belongs to the family of G-protein
24  Substitution of aspartic acid 556 of the LH/hCG receptor with glycine (D556G) creates a constitutive

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