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1 e with structural features unique to lipid A have met with success.
2 ncer with drugs that target mutated proteins have met with mixed success.
3 cidate the role of specific genetic variants have met with mixed success.
4 However, linkage studies have met with mixed success.
5 opment of RNA-targeted small molecule probes has met with limited success.
6 sing traditional approaches in bulk solution has met with limited success.
7 cute myeloid leukemia is an active area, but has met with limited success.
8 without quenching the catalytic reactivity, has met with limited success.
9 nsity of Env by modifying it in various ways has met with limited success.
10 mature immune system of the intact organism has met with limited success.
11 p care, has yielded valuable information but has met with limited success.
12 ological significance of OXDC in crop plants have met with little success.
13 ubstrate-competitive NOS inhibitors as drugs have met with little success.
14 link genetic variation to functional effects have met with little success.
15 weight glucagon receptor-binding antagonists have met with little success.
16 roduction or modification of small molecules have met with growing success.
17 ed, with descriptions of several probes that have met with in vivo success.
18 in lipodystrophies with pharmacologic agents have met with limited success.
19 water accounting for N-nitrosamine formation have met with limited success.
20 the hepatitis C virus (HCV) in cell culture have met with limited success.
21 fforts to create self-sustaining populations have met with limited success.
22 hich efforts to define subtypes behaviorally have met with limited success.
23 es (GWAS) of major depressive disorder (MDD) have met with limited success.
24 sponse with immunogens bearing MPER epitopes have met with limited success.
25 namic properties of DNA-histone interactions have met with limited success.
26 of the enzyme ADPglucose pyrophosphorylase, have met with limited success.
27 s to delineate precise genetic contributions have met with limited success.
28 s no vaccine available and current therapies have met with limited success.
29 complex traits such as common human diseases have met with limited success.
30 plausibly prebiotic polymerization reactions have met with limited success.
31 (HSCs) and progenitor cells (HPCs) in vitro have met with limited success.
32 in the visible region of the solar spectrum have met with limited success.
33 e medical treatments and surgical modalities have met with limited success.
34 he susceptibility genes for either phenotype have met with limited success.
35 ween innocent and pathological heart murmurs have met with limited success.
36 ation and adenovirus-mediated gene transfer, have met with limited success.
37 tion approaches to better classify a disease have met with limited success.
38 characterization of suppressor T cell lines have met with limited success.
39 for pancreatic ductal adenocarcinoma (PDAC) have met with limited success.
40 s to generating and testing viral immunogens have met with variable success.
41 oped strategies for rare monogenic disorders have met with some early success.
42 tion have led to surgical interventions that have met with surprising success.
43 n of otherwise promising CO2-based processes has met with only limited success.
44 e of proteins using computational techniques have met with significant success.
45 endipitously and the targeted growth of SICs has met with only moderate success.
46 acy of nanomaterials, although these systems have met with only limited success.
47 But attempts to imprint proteins have met with only limited success.
48 dus operandi for MUC16-targeted therapy, but have met with very limited success.
49 oduce the pH-dependence of protein stability have met with only limited success: agreement with exper
52 ult patients, and expansion of HSCs in vitro has met with limited success because of incomplete knowl
53 f a limited pool of working memory resources have met with some success, but the biological basis for
54 identify incursion origin(s) and pathway(s) have met with limited success due to the patchiness of a
56 to rationally design ligand-binding proteins have met with little success, however, and the computati
57 se of thalidomide as an antiangiogenic agent has met with only limited success in the treatment of ma
58 st's ability to generate protective immunity has met with some success in animal models, but the effi
60 ontrol Ca and P levels in patients with ESRD have met with early success in preventing progression of
61 at a single mediator or inflammatory pathway have met with little success in altering outcomes of cri
62 es, including cancer, but current strategies have met with only limited success in clinical and precl
63 nges resulting from education interventions, have met with some success in developed countries, but n
64 sues, and efforts to limit this inflammation have met with some success in preserving insulin sensiti
65 harmacologic and non-pharmacologic therapies have met with limited success, in part due to an incompl
67 inical settings, its applicability to humans has met with limited success largely due to inefficient
68 Efforts to block the emergence of resistance have met with limited success, largely because the mecha
69 ected inactivation of targeted RNA molecules have met with mixed success, making clear the importance
70 ated with modification of breast cancer risk has met with some limited success, perhaps because effec
71 recipients for immunosuppression withdrawal have met with limited success, perhaps because they meas
72 es directed toward initiating trigger events have met with little success, prompting concerns that su
74 hat interact with new targets, these efforts have met with limited success since the early 1960s.
75 sterol with different strategies in the past have met with limited success until the development of s
76 nipulation of parenteral nutrition solutions have met with some success, we hypothesized that basally
77 to identify genes for bipolar disorder (BD) have met with limited success, which has generally been
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