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1   Inspiration by a biological sense of taste has become a basis for the design of instruments, operat
2  capacity for antigen-directed cytotoxicity, has become a central focus for engaging the immune syste
3                                          HIV has become a chronic disease despite the effective use o
4 ication of intercellular signalling pathways has become a common analysis performed across diverse di
5 s such as vegetables (e.g., soya or coconut) has become a common source of adulteration and fraud.
6 s, angle-resolved photoelectron spectroscopy has become a core technique in the study of quantum mate
7 ms involved in response to alternative diets has become a critical concern.
8                      In recent years, cobalt has become a critical constraint on the supply chain of
9                                     Graphite has become a critical material because of its high suppl
10          As a consequence, personalized care has become a critical part of developing effective treat
11 isease, and drug overdose among young adults has become a critical public health question.
12                    Cancer biomarker research has become a data-intensive discipline requiring innovat
13     Since its initial release in 2001, SciPy has become a de facto standard for leveraging scientific
14                       Affective polarization has become a defining feature of twenty-first-century US
15                                LAA occlusion has become a favourable option in patients with atrial f
16                   Next-generation sequencing has become a first-line tool for the diagnosis of primar
17 nd inclusion among organizational membership has become a focus for many professional societies, incl
18             Detection of community structure has become a fundamental step in the analysis of biologi
19                            Childhood obesity has become a global pandemic in developed countries, lea
20                COVID-19 caused by SARS-CoV-2 has become a global pandemic requiring the development o
21 iratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic that has affected the lives
22  in antibiotic resistant pathogenic bacteria has become a global threat, which besides the developmen
23 cross-reactivity in ZIKV and DENV infections has become a great concern.
24   A wide spectrum of clinical manifestations has become a hallmark of the severe acute respiratory sy
25 ser-induced fluorescence detection (CGE-LIF) has become a key method in high-throughput glycan analys
26                         Molecular networking has become a key method to visualize and annotate the ch
27 e era of prophylaxis, Pneumocystis pneumonia has become a late-onset opportunistic infection requirin
28           Cryo-electron microscopy (cryo-EM) has become a leading technology for determining protein
29                                     ATAC-seq has become a leading technology for probing the chromati
30 inogens and understanding of carcinogenicity has become a main focus of biomedical research and regul
31                                     While BP has become a mainstay in patient care, the accuracy and
32  suzukii, has invaded Europe and America and has become a major agricultural pest in these areas, the
33 ns of transcription factors using these data has become a major challenge in genomic research.
34 biotic algae ("bleaching") under heat stress has become a major problem for reef-building corals worl
35                                 Social media has become a major source of communication in medicine.
36                       3D printing technology has become a mature manufacturing technique, widely used
37                          The "tail approach" has become a milestone in human carbonic anhydrase inhib
38                          Thus, tele-oncology has become a necessity to improve cancer care.
39                                   SARS-CoV-2 has become a pandemic worldwide; therefore, an effective
40   Dysregulation of the PI3K/Akt/mTOR pathway has become a point of convergence in autism spectrum dis
41                 Therapeutic ultrasound (TUS) has become a popular approach for improving drug penetra
42 n-synonymous to synonymous mutations (dN/dS) has become a popular method to detect selection in somat
43                                 The internet has become a popular resource to learn about health and
44 ngle-cell chromatin accessibility sequencing has become a powerful technology for understanding epige
45                                  CRISPR/Cas9 has become a powerful tool for genome editing in zebrafi
46       Ion mobility-mass spectrometry (IM-MS) has become a powerful tool for glycan structural charact
47 on imaging of fluorescent activity reporters has become a powerful tool for studying the function of
48 ycles through single-electron transfer steps has become a powerful tool in the development of catalyt
49                       Single cell sequencing has become a powerful tool to study the genome of indivi
50 an blood has been previously established and has become a predictive tool to study intravenous (IV) t
51                                       Autism has become a pressing healthcare challenge.
52                       Mass spectrometry (MS) has become a primary tool for identifying and quantifyin
53 ferent brain-imaging or behavioral variables has become a priority for the field.
54 e function within the tumor microenvironment has become a prominent therapeutic target, with tumor-as
55              Chemical vapor deposition (CVD) has become a promising approach for the industrial produ
56                               RNA modulation has become a promising therapeutic approach for the trea
57 des, but unlike in insects, an AGO duplicate has become a pseudogene.
58 donation (LKD), especially for young donors, has become a real matter of concern in the transplant co
59 en tooth surfaces based on their caries risk has become a reality to address the skewed distribution
60 g delivery system for chemotherapeutic drugs has become a research hotspot in cancer treatment.
61 dwide, secondhand exposure to e-cig aerosols has become a serious public health concern.
62            Particulate matter (PM) pollution has become a serious public health issue, especially wit
63 seudoprogression from true tumor progression has become a significant challenge in follow-up of diffu
64                                       Stress has become a significant factor, directly affecting huma
65                                   FOLFIRINOX has become a standard therapy for patients with advanced
66                                 Selenium NMR has become a standard tool for scaling the pai-accepting
67 red as ribonucleoprotein (RNP) to the zygote has become a standard tool for the development of geneti
68                         Single-cell analysis has become a state-of-art approach to heterogeneity prof
69    Since its discovery 16 years ago, roaming has become a ubiquitous mechanism in molecular photochem
70  its recent emergence, and symptom screening has become a ubiquitous tool in the global response.
71                                       Chitin has become a valuable starting material for many biotech
72 lignment tools for RNA 3D structures, STAR3D has become a valuable tool for its unprecedented speed a
73 h over 7,000 articles published, the species has become a workhorse for not only the study of self-ur
74 ding methicillin-resistant S. aureus (MRSA), has become a worldwide, major health care problem.
75                              Biologic agents have become a core component of therapeutic strategies f
76                    'No-take' marine reserves have become a cornerstone of marine ecosystem-based fish
77 es from simple, readily available feedstocks have become a cornerstone of modern synthetic organic ch
78  pathogenesis.IMPORTANCE Tick-borne diseases have become a growing threat to public health.
79            The anterior temporal lobes (ATL) have become a key brain region of interest in cognitive
80                      Chronic kidney diseases have become a major issue worldwide.
81                               Food allergies have become a significant heath burden as prevalence con
82                                    Zebrafish have become a valuable model for investigating cellular
83 and dimensional approaches to mental illness has become all too apparent.
84  (experience, mind, awareness, subjectivity) has become an accepted endeavor in contemporary neurosci
85  that the fur colouration of several species has become an accurate match to different types of deser
86           Moreover, antimicrobial resistance has become an additional challenge in the treatment of s
87                           Generating numbers has become an almost inevitable task associated with stu
88 rgeting cancer-associated fibroblasts (CAFs) has become an attractive goal for diagnostic imaging and
89 naling occurs frequently in cancers, so mTOR has become an attractive target for cancer therapy.
90         We conclude that background matching has become an effective and common adaptation against pr
91 The transition-metal-promoted C-H activation has become an efficient as well as atom-economic methodo
92 noparticles (NPs) in the aquatic environment has become an emerging concern in terms of environmental
93 uid chromatography-mass spectrometry (LC-MS) has become an essential analytical technique to quantify
94       Single-cell RNA sequencing (scRNA-seq) has become an essential tool for characterizing gene exp
95 nce microscopy, imaging flow cytometry (IFC) has become an established tool for cell analysis in dive
96 in being used in antifouling coatings, as it has become an existential threat to nontargeted species
97                  Passive acoustic monitoring has become an important data collection method, yielding
98 bee gut microbiota influences bee health and has become an important model to study the ecology and e
99  total bioaerosols in different environments has become an important task for safeguarding against bi
100              Mass spectrometry imaging (MSI) has become an important tool for 2D profiling of biologi
101                       Mass spectrometry (MS) has become an important tool for determining protein HOS
102        Electron paramagnetic resonance (EPR) has become an important tool to probe conformational cha
103 ls to improve recombinant protein production has become an important tool, but is still rarely applie
104 inclusion in professional society membership has become an important topic for many scientific fields
105 utaneous pulmonary valve implantation (PPVI) has become an important treatment of right ventricular o
106                                K. pneumoniae has become an increasing concern due to the rise and spr
107 llin allergy de-labeling as an aspect of ASP has become an increasing global focus.
108 of antimicrobial stewardship programs (ASPs) has become an increasing global focus.
109                 Cardiovascular disease (CVD) has become an increasingly common limitation to effectiv
110                       : Laparoscopic surgery has become an increasingly popular alternative approach
111 ional annotation of shotgun metagenomic data has become an increasingly popular method for identifyin
112 arse-grained modeling of conjugated polymers has become an increasingly popular route to investigate
113 decades, X-ray absorption spectroscopy (XAS) has become an indispensable method for probing the struc
114 riptome analysis by RNA sequencing (RNA-seq) has become an indispensable research tool in modern plan
115 the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular b
116 ng a high-quality genome assembly/annotation has become an indispensable tool for better understandin
117                                     Modeling has become an indispensable tool for scientific research
118                              Genetic testing has become an integral component of the diagnostic evalu
119  media and online-communication applications has become an integral part of everyday life, some indiv
120 ue to the 24hr nature of society, shift work has become an integral part of many industries.
121 sed on molecularly imprinted polymers (MIPs) has become an interesting field for environmental monito
122 emic, the conduct of elective cancer surgery has become an issue because of the need to balance the r
123 ak of a novel respiratory virus, SARS-CoV-2, has become an ongoing global pandemic due in part to the
124 ntaminants at trace levels in tissue samples has become an unmet need around the globe.
125            Residual Dipolar Couplings (RDCs) have become an alternate approach for structure calculat
126 se separation, and membraneless compartments have become an important area of cell biology research w
127                    Host-modulating therapies have become an important focus in the development of nov
128                        Microbial communities have become an important subject of research across mult
129                      Neutralizing antibodies have become an important tool in treating infectious dis
130                which, once discovered, would have become an indispensable part of daily life.
131 as ErbB3-binding protein 1 (EBP1), in cancer has become apparent over the past 20 years.
132                     In recent literature, it has become apparent that radiologic images can serve as
133 cepts that remain useful, letting go of what has become archaic, and introducing new concepts and met
134       A broad spectrum of analytical methods has become available over the last five years, such that
135     Recently, plasma separation cards (PSCs) have become available and, though more expensive, have l
136 n the recent years two innovative approaches have become available for minimally invasive en bloc res
137 apture (Hi-C) assays in lymphoblastoid cells have become available, enabling us to precisely map the
138 pt came into the limelight ten years ago, we have become aware that responses of holobionts to climat
139  authors have informed the Journal that they have become aware that some of the data in this article
140 hose from furnishings and building materials have become better regulated and energy efficient homes
141 iological processes underlying these effects have become better understood.
142                                  Thus, ASICs have become bona fide neurotransmitter-gated ion channel
143 saurs took flight and subsequently appear to have become capable and efficient flyers.
144 owever, with 11 000 annual publications this has become challenging.
145                              Furthermore, it has become clear that ARV therapy does not fully restore
146               Over the last several years it has become clear that higher order assemblies on membran
147                            More recently, it has become clear that mammalian genomes encode thousands
148                     Over the last decade, it has become clear that respiratory and intestinal tract m
149 d to these stresses and over recent years it has become clear that sphingolipids are a key player in
150 olipids and sphingolipid metabolites, and it has become clear that the intracellular sphingolipid com
151                                     While it has become clear that the percentage of rhythmic genes v
152 own dramatically in the past decade as it is has become clear that they are ubiquitous and have a muc
153 ain insight into solute-solvent interactions have become clear relatively recently.
154                             These influences have become clearest in nanoscale experiments, in terms
155  bacteria and expressed in Escherichia coli, has become commercially available.
156 owever, the importance of gray matter damage has become critical in understanding the long-term progr
157 y contrast, at 19 weeks, when motor deficits had become dramatically evident, both measures were foun
158 s in year-round flowering, we show flowering has become earlier for all communities except at the hig
159 methods coupled with stable isotope dilution have become effective and widely used methods for the de
160  caused by an unknown spectrum of prions and has become enzootic in populations of cervid species tha
161  expected even though parents of this cohort have become especially aware of allergic reactions to fo
162 rug repositioning and drug-target prediction have become essential tasks in the early stage of drug d
163 enabled approaches to molecular epidemiology have become essential to public health agencies and the
164 rogen isotopes deuterium (D) and tritium (T) have become essential tools in chemistry, biology and me
165          Since their discovery in 2007, CMPs have become established as an important subclass of poro
166                              These questions have become even more topical with the recent progress b
167 ough this process is quite time-consuming, I have become familiar with every paper that we publish.
168                                        TEVAR has become first-line therapy for many aortic pathologie
169           Direct oral anticoagulants (DOACs) have become first-line treatment for venous thrombotic e
170     Scorpions are among the first animals to have become fully terrestrialised.
171 l-time measurement of single cell secretions have become grand research barriers.
172   As exacting as genetic and genomic testing have become, health professionals continue to encounter
173 Countries in Latin America and the Caribbean have become hotspots of the novel coronavirus (COVID-19)
174          However, HA antigenic site B, which has become immunodominant in recent human H3N2 influenza
175  protocols for research and clinical studies has become important in order to optimize diagnostic uti
176 rout such lines have existed for decades and has become important research tools in genome studies as
177 ack of MMP-selective agents; accordingly, it has become important to identify a platform with which h
178 nd development of targeted protein degraders have become important areas of research in the field of
179  metabolic and physiologic imaging of tumors have become important for treatment planning and respons
180 n and dipeptide repeat proteins in biofluids have become important potential measures of therapeutic
181 he prostate-specific membrane antigen (PSMA) have become important tools in the diagnosis and treatme
182 itative analysis of mitochondrial morphology has become increasingly accessible, there is a need for
183                                           It has become increasingly appreciated that autoimmune resp
184 us rights and interests in genetic resources has become increasingly challenging in an open science e
185                                  As such, it has become increasingly clear that a dissection of varia
186 ly passive recorders of ocean conditions, it has become increasingly clear that biological processes
187     However, over the last several years, it has become increasingly clear that multiple aspects of k
188            Over the past several decades, it has become increasingly clear that women have distinct c
189 ns and fragment libraries for drug discovery has become increasingly common.
190                   Quantum process tomography has become increasingly critical as the need grows for r
191 iling of enhancer activities genome-wide, it has become increasingly evidenced that this classical de
192 rain injury, and neurodegenerative diseases, has become increasingly evident.
193 ility of photonic integrated circuits (PICs) has become increasingly important due to the growing dem
194 mplex cardiovascular needs of these patients has become increasingly important, resulting in an imper
195 ape how we perceive and comprehend the world has become increasingly influential in the field of syst
196             Spreading rumors on the Internet has become increasingly pervasive due to the proliferati
197 ver the past decade, bifactor model analysis has become increasingly popular as a statistical approac
198                    Yet, circadian disruption has become increasingly prevalent within today's society
199 ic concentrations of carbon dioxide (pCO(2)) has become increasingly relevant as modern concentration
200 of cells when subjected to mechanical impact has become increasingly relevant for accurate assessment
201 al assays enabling high-throughput screening have become increasingly interesting.
202                    Although ancient DNA data have become increasingly more important in studies about
203  hydrogels yields novel superstructures that have become increasingly popular in biomedical research.
204                                 VLNT and LVB have become increasingly popular in the treatment of lym
205 gorithms to convert spoken language to text, have become increasingly widespread, powering popular vi
206                                      The EHR has become integral to perioperative care.
207 ful building blocks in organic synthesis and have become invaluable starting materials for the constr
208  rise to Fano-Feshbach resonances (FFR) that have become key to understanding and controlling interac
209 reproduction will be reduced because masting has become less effective at satiating seed predators.
210      This article provides evidence that TDC has become less reliable as the accuracy of modern mass
211 ts in 90% of the 134 most populous countries have become less connected since 1975, while just 29% sh
212                              Trauma patients have become less likely to be discharged home than other
213           Since the late 1980s, both indices have become less relevant to physical-ecological variabi
214 ynthesized proteins and refolding those that have become misfolded in the context of a crowded cytoso
215 demonstrate that world-wide yield volatility has become more common in the current most decades, asso
216      Use of prediction models in oral health has become more common over the past decades for predict
217                                  Deportation has become more commonplace in the United States since t
218 n of most CO(2) and suggests that the mantle has become more depleted in carbon over geologic time.
219 potency paradox", farmland in the central US has become more hazardous to bees despite lower volumes
220 ecently, the relevance of non-HLA antibodies has become more prominent as AMR can be diagnosed in the
221                        As genomic sequencing has become more widely available, the high prevalence of
222                 Compared with 2005, programs have become more accepting of hypertensive candidates: 6
223 lastic abundances in freshwater environments have become more common in the past five years, but few
224  grass evolution and the reactions catalyzed have become more complex with time.
225 anial microsurgery procedures to deploy them have become more complex.
226 ic effect of estrogen on gallstone formation have become more complicated with the identification of
227       Methods for autonomous experimentation have become more sophisticated recently, allowing for mu
228                   Compared to 2005, programs have become more stringent in accepting younger candidat
229 ections difficult to treat, as K. pneumoniae has become multidrug resistant.
230                           In recent years it has become obvious that protein complexes and lipids are
231 s related to interactions with nanomaterials has become of interest due to its therapeutic potential.
232                             Chiral compounds have become of great interest to the pharmaceutical indu
233 rotease and ligase activity, plant legumains have become of particular biotechnological interest, e.g
234                               Gold catalysis has become one of the fastest growing fields in chemistr
235 ion during both normal development and aging has become one of the fastest growing topics in biology.
236 , acquisition of large-scale phenotypic data has become one of the major bottlenecks hindering crop b
237            The zebrafish species Danio rerio has become one of the major vertebrate model organisms u
238                The amination of aryl halides has become one of the most commonly practiced C-N bond-f
239                 Gene set enrichment analysis has become one of the most frequently used applications
240       Programmed cell death protein 1 (PD-1) has become one of the most investigated targets for canc
241                                  3D printing has become one of the most promising methods to construc
242                    Infection with SARS-CoV-2 has become pandemic and the duration of protective immun
243    COVID-19, caused by the SARS-CoV-2 virus, has become pandemic.
244  Shewanella oneidensis (S. oneidensis) MR-1, has become particularly alluring, thanks to its extraord
245 gnment-free methods for sequence comparisons have become popular in many bioinformatics applications,
246         Electronic cigarettes (e-cigarettes) have become popular, in part because they are perceived
247 f the dynamically harmonized FT ICR cell, it has become possible to achieve the resolving power of mo
248              Using 5 mm x 2.1 mm columns, it has become possible to separate antibody fragments and a
249 ectants, drinking water distribution systems have become potential geogenic sources for hexavalent ch
250           Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and di
251 onal connectivity, and functional alignment, have become powerful tools in cognitive neuroscience ove
252 udes important opportunistic pathogens which have become public health priorities linked to major hos
253 f mason bee (Osmia taurus and O. cornifrons) have become recently established.
254                              As a result, it has become recognized as a privileged structural feature
255 re of the thrombotic disease observed, which has become refractory to oral anticoagulation.
256                       Metastatic tumors that have become resistant to androgen deprivation therapy re
257             Glacier ice in the Southern Alps has become restricted to higher elevations and to large
258                       PTM catalyzing enzymes have become significant drug targets, and therefore, tre
259         Three out of six SARS-CoV-2 subtypes have become slightly more infectious, while the other th
260 uman Phenotype Ontology (HPO)-based analysis has become standard for genomic diagnostics of rare dise
261  Assessing measurable residual disease (MRD) has become standard with many tumors, but the clinical m
262        Select field phenotyping technologies have become state of the art and show promise for speedi
263                    Other mammalian receptors have become targets through which pathogens enter target
264  X-linked homolog of a bull Y-amplified gene has become testis-specific and amplified.
265                                  Natural gas has become the dominant source of electricity in the Uni
266                                Deep learning has become the dominant technology for protein contact p
267      Using sunitinib to improve the survival has become the first-line therapy for metastatic RCC pat
268 RNA), produced through alternative splicing, has become the focus of scientific studies due to its ma
269 se-Producing Organisms (CPO), where colistin has become the last-resort antibiotic treatment.
270 asing knowledge about biological systems and has become the main driver for innovations in the field
271                      This resistance profile has become the main problem of public health infections.
272 age) of the disease to a specific treatment, has become the main proposed treatment strategy for the
273 nes is an RNA-guided DNA endonuclease, which has become the most popular genome editing tool.
274                    In the past 20 years, MRI has become the most useful paraclinical tool in both sit
275 scle actin in 1981, the pyrene-labeled actin has become the most widely employed tool to measure the
276 on of microbial nucleic acids in body fluids has become the preferred method for rapid diagnosis of m
277 m-catalysed borylation of aromatic C-H bonds has become the preferred method for the synthesis of aro
278 scription polymerase chain reaction (RT-PCR) has become the primary method to diagnose viral diseases
279  Thoracic endovascular aortic repair (TEVAR) has become the primary surgical treatment modality for d
280     With about 800 curated models, BioModels has become the world's largest repository of curated mod
281 nd specific nucleic acid amplification tests have become the diagnostic reference standard for viruse
282  simulation and normal mode analysis methods have become the gold standard for studying protein dynam
283 population, and intensive curative therapies have become the standard.
284 al interpretation for differential diagnosis has become time-consuming and challenging.
285 eep learning networks to real-world problems have become ubiquitous, our understanding of why they ar
286 extreme topography on the cellular level and have become useful tools for perturbing and sensing the
287 Recently, bicyclo[1.1.1]pentane (BCP) motifs have become valuable as pharmaceutical bioisosteres of b
288 n applications related to process monitoring has become very popular since non-linearities in the rel
289                                     Meetings have become visibly more diverse, due in part to ethnic
290                   In contrast, early feeding has become well established in the adult population, whe
291  the first reports, the utility of native MS has become well established in the structural biology co
292 rexpressed in a wide spectrum of cancers and have become well validated therapeutic targets.
293 .25 degrees C more than daytime warming, and has become wetter, with important consequences for plant
294 the general presence of membrane nanodomains has become widely accepted as fact, fundamental function
295 in particular 1,3-disubstituted BCP moieties have become widely adopted in medicinal chemistry as par
296 ecific antibodies with asymmetric constructs have become widely used formats for therapeutic applicat
297                The cell aggregates-spheroids-have become widely used model objects in the study of th
298           Droplet-based microfluidic devices have become widely used to perform single-cell RNA seque
299                                           It has become widespread in the field to attribute broad lu
300 lso been developed over the past decade, and have become widespread in many fields, including infecti

 
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