ライフサイエンスコーパス: ha(ve|s|d) become

1 Phase mapping has become a broadly used technique to identify atrial r

2 This method has become a central facet of drug discovery campaigns i

3 s between LAR and nonallergic rhinitis (NAR) has become a challenge for the clinician.

4 (HSCs) to treat genetic blood cell diseases has become a clinical standard but is limited by the ava

5 ankfull flow and the incipient motion of D50 has become a commonly used assumption.

6 TEK has become a construct that Western scientists have incr

7 ed with spectral detectors, spectral imaging has become a convenient and powerful technique for measu

8 lective modification of complex biomolecules has become a cornerstone of chemical biology.

9 CRISPR-Cas9 has become a facile genome editing technology, yet the s

10 l role of anti-VEGF treatment for type 1 ROP has become a focus in recent years, but the protracted r

11 pulmonary artery pressure-guided management has become a focus of hospitalization reduction in heart

12 t and characterization of the gut microbiome has become a focus of research in the area of human auto

13 the 21st century, inflammatory bowel disease has become a global disease with accelerating incidence

14 broad spectrum of commonly used antibiotics has become a global health-care problem.

15 Metabolic syndrome (MetS) has become a global public health problem affecting all

16 Obesity is increasing in prevalence and has become a global public health problem.

17 poB S531L mutation in RNA polymerase (RNAP), has become a growing problem worldwide.

18 High-resolution mass spectrometry has become a key technology in life sciences.

19 zation, and identifying a suitable mechanism has become a key unanswered question in the origin of li

20 Nonalcoholic steatohepatitis (NASH) has become a major cause of cirrhosis and liver-related

21 With improved survival, heart failure (HF) has become a major complication for individuals with hum

22 This has become a major limitation to understanding the role

23 significance of the constricted conformation has become a matter of debate.

24 The high rate of handicap has become a matter of medical and social consideration.

25 In view of this result, pembrolizumab has become a new treatment option for patients who are c

26 As such, the mouse visual system has become a platform for multilevel analysis of the mam

27 at target translocator protein 18 kDa (TSPO) has become a popular approach to assess putative neuroin

28 The study of wearable devices has become a popular research topic recently, where high

29 d radical polymerization (SI-CRP) techniques has become a powerful approach to tailor the chemical an

30 ngle molecule localization microscopy (SMLM) has become a powerful imaging tool for biomedical resear

31 nt years, optical coherence tomography (OCT) has become a powerful skin imaging technique.

32 pled with chemical cross-linking of proteins has become a powerful tool for proteins structure and in

33 The Drosophila visual system has become a premier model for probing how neural divers

34 te diagnosis of Zika virus (ZIKV) infections has become a pressing need for the effective prevention

35 Mass spectrometry has become a primary tool for glycan analysis thanks to

36 Zika virus (ZIKV) has become a public health threat due to its global tran

37 radiation and thermal combined injury (RCI) has become a real threat with devastating immunosuppress

38 Cone beam computed tomography (CBCT) has become a reliable adjunctive tool for both diagnosis

39 Kidney transplantation has become a routine procedure in the treatment of patie

40 Zika virus (ZIKV) has become a serious public health concern because of it

41 Western hemisphere, from Africa via Asia, it has become a serious threat to pregnant women, causing m

42 tance, especially of Gram-negative bacteria, has become a severe concern for human health.

43 d rabies virus-mediated monosynaptic tracing has become a standard method for neuronal circuit mappin

44 Mapping-by-sequencing has become a standard method to map and identify phenoty

45 chemoradiotherapy (nCRT) followed by surgery has become a standard of care for esophageal adenocarcin

46 nce during central venous catheter insertion has become a standard of care, postinsertion chest radio

47 zation, such as flux balance analysis (FBA), has become a standard systems-biology computational meth

48 Optical coherence tomography (OCT) has become a standard-of-care in retinal imaging.

49 truction, percutaneous coronary intervention has become a standard-of-care procedure over the past 40

50 y driven by pushing technological limits, it has become a tool of biological discovery.

51 torm intensity to climate variability/change has become a topic of community interest recently.

52 biology, and energy, their surface chemistry has become a topic of intensive research interest.

53 -related quality of life (HRQoL) measurement has become a valuable metric to assess the effects of di

54 programs represents one such innovation that has become a valuable tool in donation systems around th

55 g and developing inhibitors of these enzymes has become a very active and fast-growing research area

56 g known drugs for new anticancer indications has become a viable alternative.

57 IV-positive individuals, a kidney transplant has become a viable option for many who have progressed

58 ranscatheter aortic valve replacement (TAVR) has become a well-accepted option for treating patients

59 Peptide receptor radionuclide therapy (PRRT) has become a well-accepted treatment for patients with w

60 Genome-wide association study (GWAS) has become a widely accepted strategy for decoding genot

61 odel (iHMM), generalizes the HMM that itself has become a workhorse in single molecule data analysis.

62 s illustrates how optical absorption methods have become a competitive alternative to state-of-the-ar

63 Sequence logos have become a crucial visualization method for studying

64 Outbreaks of foodborne diseases have become a global health concern; hence, many improve

65 t allele-specific DNA methylation (hap-ASM), have become a major focus in the post-genome-wide-associ

66 ed particles and characterising their motion have become a major scientific challenge over the past f

67 Comorbidity patterns have become a major source of information to explore sha

68 Patient-derived xenografts (PDXs) have become a prominent cancer model system, as they are

69 Multidrug resistant bacterial pathogens have become a serious global human health threat, and co

70 Cultured stem cells have become a standard platform not only for regenerativ

71 hospital admissions or emergency procedures have become a topical and controversial issue for the UK

72 hase substrates for biomolecule manipulation have become a valuable tool for simplification and autom

73 nostic assays during the last decade, ELISAs have become a workhorse in routine clinical diagnostics.

74 Opiate abuse and addiction have become a worldwide epidemic with great societal and

75 Recently, experimental systems have become accessible to probe the dynamics of nanofric

76 nd over 35 transplants later, public opinion has become accustomed to the concept of "face restoratio

77 these different macrophage activation states have become active areas of research.

78 metabolomics analysis of human biospecimens has become among the most promising strategies for probi

79 ndependent risk factors that either arose or have become amplified in the postindustrial era.

80 r terahertz wireless communications networks has become an active and growing research field.

81 ets for green technologies, HRE-free Nd-Fe-B has become an attractive option.

82 Recently, mutp53 has become an attractive target for cancer therapy.

83 ys a role in many pathological disorders, it has become an attractive target for the development of i

84 t is not surprising that the Hsp90 machinery has become an attractive therapeutic target for diseases

85 Mass spectrometry has become an enabling technology for the investigation

86 Photoredox catalysis has become an essential tool in organic synthesis becaus

87 Mathematical modelling has become an established tool for studying the dynamics

88 Over the past few decades, NMR spectroscopy has become an established tool in drug discovery.

89 Fluorine has become an important element for the design of synthe

90 Triploid fish has become an important item of commercial aquaculture,

91 comparison or differential network analysis has become an important means of revealing the underlyin

92 Mass spectrometry-based protein analysis has become an important methodology for proteogenomic ma

93 Morbidity rate has become an important outcome measure, as the mortalit

94 cy catheter ablation for atrial fibrillation has become an important therapy for AF; however, recurre

95 ion imaging (CDI) in the extreme ultraviolet has become an important tool for nanoscale investigation

96 Tissue clearing has become an important tool for the investigation of bi

97 Although iminium catalysis has become an important tool in organic chemistry, its c

98 Meal skipping has become an increasing trend of the modern lifestyle t

99 as an urgent rather than emergency procedure has become an increasingly common practice in children.

100 systems with Nitrogen-Vacancy centers, which has become an increasingly important platform for quantu

101 Mass spectrometry (MS) has become an indispensable tool for investigating the a

102 Magnetic resonance imaging (MRI) has become an indispensable tool in the diagnosis and tr

103 Cardiovascular magnetic resonance imaging has become an indispensable tool in the evaluation of co

104 sibly reconfigurable plasmonic nanomaterials has become an intensive research area offering the oppor

105 creening method for potential food allergens has become an urgent need in order to protect the sensit

106 initiating or being part of the p53 response have become an actively studied research area in the p53

107 Cationic nanohydrogel particles have become an attractive tool for systemic siRNA delive

108 They have become an immunology hotspot, implicated in infecti

109 Shifts in the timing of life history events have become an important source of information about how

110 y, the anti-PD-L1 and -PD-1 immune therapies have become an important tool for treatment of advanced

111 Antibodies have become an indispensable tool for many biotechnologi

112 Quality improvement (QI) initiatives have become an integral part of patient-centered care.

113 etect, channel, and respond to these signals have become an intense area of study for developing stra

114 Over the last 2 decades, it has become apparent that AMPK regulates several other ce

115 Furthermore, it has become apparent that much of this life is dependent

116 Despite this, it has become apparent that our initial understanding of AT

117 It has become apparent that the immune system evolved multi

118 e use of unactivated olefins for alkylations has become attractive from both cost and sustainability

119 tinamide adenine dinucleotide phosphate, and have become attractive biocatalysts for organic synthesi

120 table, real-time, nanopore sequencing (RTnS) has become available.

121 rpose Since 2000, many new treatment options have become available for relapsed and/or refractory mul

122 expression quantitative trait loci) catalogs have become available that can help understand the funct

123 Recently, regimens have become available that might improve HCW acceptance

124 reasing number of commercial molecular tests have become available to diagnose respiratory viral infe

125 chnology, X-rays with small enough bandwidth have become available, allowing the investigation of the

126 ays for the detection of uromodulin in blood have become available.

127 No new treatments since natamycin have become available.

128 mmunities under naturally occurring extremes have become central for improved predictions of future r

129 Interim and end-of-treatment PET/CT have become central to the evaluation of Hodgkin and non

130 el for the study of integrin biology, and it has become clear that integrin outside-in signaling is h

131 In recent years, it has become clear that platelets also act as modulators o

132 primary role in substrate translocation, it has become clear that some transporters have acquired a

133 Recently, it has become clear that the mammalian heart is not a post-

134 Over the past few years, it has become clear that, at the pathophysiological level,

135 low-up, a large proportion of the infections had become cleared (34-100%), or the pathogen load reduc

136 Bleaching of vital teeth has become common practice in cosmetic dentistry today.

137 ch as cholera, meningitis, and yellow fever, have become common over the past decade, hampering effor

138 hepatitis C virus (HCV) treatment strategies have become common, but few appear to include patient en

139 Blooms of alien invasive marine algae have become common, greatly altering the health and stab

140 how and why simple non-coded peptides could have become critical for RNA function is unclear.

141 , the research on online commercial networks has become crucial for filtering out irrelevant informat

142 It has become crucial in drug trials and to follow individu

143 tion landscape for fragments with 40 repeats has become downhill.

144 ss their breeding range to test whether they have become ecologically trapped in the degraded Benguel

145 ue, West Nile encephalitis, and chikungunya, have become endemic or have caused dramatic epidemics in

146 n of bacterial susceptibility to antibiotics has become essential in many clinical settings and, some

147 predicted and native structures of proteins have become essential for driving the acceptance and ado

148 Bioinformatics skills have become essential for many research areas; however,

149 ynamic or controllable fluorescence emission have become essential tools for advanced imaging, such a

150 ings where the quintuple dhfr/dhps haplotype had become established but where in vivo efficacy data s

151 methane leakage from the natural gas system have become ever more prominent in recent years.

152 In the past 2 decades, it has become evident that individuals born with congenital

153 It has become evident that nonlymphoid tissues are populate

154 small cell carcinoma of the urinary bladder has become evident.

155 Targeted drug delivery has become extremely important in enhancing efficacy and

156 ic full-contour zirconia restorations, which have become extremely popular in a short period of time,

157 For example, the Sleeping Beauty transposon has become highly instrumental to induce tumors in exper

158 liferation and differentiation potential, or have become immortalized cells.

159 viously subdominant, conserved lateral patch had become immunodominant for individuals with B-cell me

160 molecule manipulation and imaging techniques have become important elements of the biologist's toolki

161 Songbirds like the zebra finch have become important models to understand the brain syn

162 plex glycoligands on a variety of scaffolds, have become important tools for studying the role of car

163 Molecular assays have become important tools for the diagnosis and manage

164 gle channel or red-green-blue (RGB) channels have become inadequate for the new challenges of fluores

165 Finally, research has become incorporated in care.

166 dized, suggesting that monomeric U(IV) might have become incorporated in newly formed iron precipitat

167 Cannabis use has become increasingly accepted socially and legally, f

168 In recent years it has become increasingly clear that articular cartilage h

169 Pediatric hospital care has become increasingly concentrated, and many children

170 rect analysis by mass spectrometry (imaging) has become increasingly deployed in preclinical and clin

171 In the past decade, it has become increasingly evident that several important d

172 in sex differences is human lifespan, which has become increasingly female-biased in recent centurie

173 l or functional measures of the human brain, has become increasingly important in recent years.

174 Therefore, the targeting of PSMA has become increasingly important over the last decade.

175 Social media has become increasingly important over the past decades

176 This type of microecological study has become increasingly important, especially with the e

177 uantitative traits and physiological markers has become increasingly more important, as this may lead

178 tanding a tumor's detailed molecular profile has become increasingly necessary to deliver the standar

179 content during winemaking and bottle storage has become increasingly popular due to its impact on the

180 nt years, texture analysis of medical images has become increasingly popular in studies investigating

181 omprehensive liquid chromatography (LC x LC) has become increasingly popular.

182 etection in food and feedstock in particular has become increasingly relevant as these toxins, such a

183 bond formation and noncovalent interactions has become increasingly relevant.

184 r of harnessing T-cell co-signaling pathways has become increasingly understood to have significant c

185 d cellular function, morphological profiling has become increasingly utilized to better understand fu

186 enesis by regulators of proteolytic pathways have become increasingly apparent.

187 Assisted reproductive therapies (ART) have become increasingly common worldwide and numerous r

188 gest that Fresno's land and water management have become increasingly disconnected in recent years, w

189 cells and tissues, that is, humanized mice, have become increasingly important as small, preclinical

190 Rare earth elements (REEs) have become increasingly important in modern day technol

191 In recent years evolutionary ecologists have become increasingly interested in the effects of re

192 blooms of the cyanobacterium Microcystis sp. have become increasingly pervasive in the San Francisco

193 studies (GWAS) with "time to event" outcomes have become increasingly popular, predominantly in the c

194 fication and characterization of the disease have become increasingly precise through improved risk s

195 ntrast, since 2000, pharmaceutical companies have become increasingly profitable, with risk-adjusted

196 Studies of the microbiome have become increasingly sophisticated, and multiple seq

197 s have been expressed that operators/centers have become increasingly unfamiliar with transfemoral ac

198 Polymeric nanoparticles have become indispensable in modern society with a wide

199 Although balanced resuscitation has become integrated into massive transfusion practice,

200 eless incisions, and topical anesthesia also have become key components of standard treatment.

201 cells (iPSCs), and cells derived from them, have become key tools for modeling biological processes,

202 innate immune checkpoint is composed of what has become known as the 'don't-eat me' signal CD47, whic

203 ion and collaboration between the two fields has become less commonplace.

204 However, recently this investment has become less diversified, with a larger fraction of g

205 ely preterm infants (<28 weeks of gestation) has become less invasive, but it is unclear whether such

206 ment, targeting optimal gas exchange in ARDS has become less of a priority compared with prevention o

207 As nonacademic careers in science have become less and less "alternative," one field that

208 Massive slums have become major features of cities in many low-income

209 r the N-glycan sites, suggesting this region had become more ordered in the anchorless state.

210 hile the collective impact of marine viruses has become more apparent over the last decade, a deeper

211 Yet the choice of antibiotic therapy has become more challenging due to recent reports of nep

212 uring the last decade, and patient treatment has become more complex.

213 h the advent of the Internet, drug discovery has become more decentralised, bottom-up, and scalable t

214 ing very large contact angles (>150 degrees) has become more relevant with the increased popularity o

215 Surgery has become more standardised and centralised.

216 Because molecular testing has become more widely used, we explored the extent of p

217 ses of drug resistance among these pathogens have become more frequent, requiring the development of

218 Even though personal computers have become more powerful, data transfer times still rep

219 are unit (CICU), noncardiovascular illnesses have become more prevalent and may contribute to morbidi

220 tinguish because skipping meals and snacking have become more prevalent.

221 wly industrialised countries whose societies have become more westernised.

222 These methods have become more widely applied in neuroscience.

223 Atmospheric deposition has become negligible, while volatilization from the wat

224 hough higher harmonic generation from solids has become of interest in many fields, its observation i

225 prevent infections caused by these bacteria has become of major interest.

226 zation of surface composition and reactivity have become of extreme importance.

227 essing humoral and innate cellular responses has become one focus of research to develop innovative s

228 Diabetes mellitus has become one of the biggest medical challenges affecti

229 utcome at the level of the cell and organism has become one of the great frontiers of modern chemical

230 PNS has become one of the main constraints on the use of hig

231 Thus, it has become one of the most challenging tasks in systems

232 Clostridium difficile has become one of the most common bacterial pathogens in

233 iversary, percutaneous coronary intervention has become one of the most common medical procedures wor

234 DNA has become one of the most extensively used molecular bu

235 Probiotics have become one of effective alternatives to antibiotics

236 roperties, while their single-layer variants have become one of the most prominent examples of two-di

237 Supercapacitors have become one of the most promising energy-storage sys

238 of fragments even with preactivation, which has become particularly problematic for the study of lar

239 Immune checkpoint blockers (ICB) have become pivotal therapies in the clinical armamentar

240 Inhomogeneous solvation theory (IST) has become popular for treating this effect, but it has

241 Recently proteomics-based approaches have become popular.

242 Thus it has become possible for a clinician to evaluate individu

243 gh-resolution intravital imaging of the lung has become possible through the utilization of vacuum-st

244 In recent years, it has become possible to carry out reactions directly on t

245 decades that an overview of the entire flora has become possible.

246 (MRI), in-vivo analysis of brain structures has become possible.

247 celerated our understanding about cancer and have become potent tools in our fight against the diseas

248 stems in prokaryotes whose effector proteins have become powerful tools for basic research and biotec

249 ithmic advances, machine learning techniques have become powerful tools for finding patterns in data.

250 t puncture biological or synthetic membranes-have become powerful tools in chemical- and biosensing,

251 Recently whole exome sequencing (WES) has become primary strategy for sequencing patient sampl

252 ia used to characterize therapeutic response have become progressively more varied and complex.

253 Simple lag hypotheses have become prominent in disequilibrium ecology, proposi

254 rocess has been incredibly time-consuming, I have become quite familiar with every paper that we publ

255 With newer preparations, HSRs have become rarer; however, severe reactions may still o

256 egy for patients with ALK-positive NSCLC who have become resistant to currently available TKIs, inclu

257 Patients die from recurrent tumors that have become resistant to therapy.

258 application of whole-genome sequencing (WGS) has become routine for trace back investigations, with c

259 d over the past three decades, these systems have become selective, sensitive, and affordable.

260 pecially in countries where smoking patterns have become similar between women and men.

261 ery controversial when initially introduced, have become state of the art.

262 electron microscopy (EM) of serial sections has become the de-facto standard for reconstruction of n

263 Active surveillance has become the dominant management for low-risk prostate

264 Although ultrahigh-throughput RNA-Sequencing has become the dominant technology for genome-wide trans

265 This helicase has become the focus of extensive basic research on the

266 Cardiovascular magnetic resonance imaging has become the gold standard for evaluating myocardial f

267 Quantitative PCR (qPCR) has become the gold standard technique to measure cDNA a

268 m of functionally related genes or pathways) has become the method of choice for analyzing omics data

269 rs, health facilities, and ambulances, Syria has become the most dangerous place on earth for health-

270 Since its discovery, CRISPR-Cas9 has become the most robust platform for genome engineeri

271 etal complexes with chiral ligands are used, has become the most valuable methodology for the prepara

272 . Paul, MN) model of acute skin inflammation has become the most widely used mouse model in preclinic

273 Cardiac magnetic resonance imaging (cMRI) has become the non-invasive reference standard for the e

274 e NhaA crystal structure of Escherichia coli has become the paradigm for this class of secondary acti

275 h the intent to cure) appears to be safe and has become the preferred approach for men with less-aggr

276 Renal transplantation has become the preferred treatment for end stage kidney

277 attering by nanostructures and point defects has become the primary strategy for minimizing the latti

278 Transcatheter aortic valve replacement has become the procedure of choice for inoperable, high-

279 e of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacterial species id

280 Whereas stereochemical purity in drugs has become the standard for small molecules, stereoisome

281 Cross-sectional X-ray imaging has become the standard for staging most solid organ mal

282 Radiofrequency catheter ablation has become the treatment strategy of choice for atrial t

283 uences, subtractive hybridization procedures have become the approach of choice prior to RNA-seq, wit

284 A sequencing technologies, omics experiments have become the mainstay for studying diverse biological

285 eading through South America's Patagonia and have become the most widespread anadromous salmon invasi

286 sed on recent proficiency test surveys, they have become the predominant method used for CDI diagnosi

287 locus genome-wide association studies (GWAS) have become the state-of-the-art procedure to identify q

288 overexpressed in the failing heart and thus have become therapeutic targets.

289 ) were analyzed retrospectively; 22 patients have become tolerant (median age at tolerance acquisitio

290 This approach has become transformative for the delivery of RNAi thera

291 though fungal genome sequencing and assembly have become trivial, its annotation procedure has not be

292 er time the basic tenets of these hypotheses have become unclear.

293 rates from coronary heart disease and stroke has become unmistakable throughout the industrialized wo

294 times have advanced over time and as spring has become warmer.

295 s, correlations between population and PM2.5 have become weaker in Europe and North America due to ai

296 n-of-function mutations associated with PIDs has become well recognized and adds a new dimension to t

297 sociated with a reduced graft survival rate, has become widely adopted in elderly recipients in an ol

298 ortase A (SrtA), a bacterial transpeptidase, has become widely used for its ability to site-specifica

299 In recent years, nanoplasmonic sensors have become widely used for the label-free detection of

300 Genome-scale metabolic modeling has become widespread for analyzing microbial metabolism