ライフサイエンスコーパス: haemagglutinin

1 lagen-binding phenotype was unique to the Dr haemagglutinin.

2 e ruptured with membrane edges stabilized by haemagglutinin.

3 the immunodominant receptor binding protein, haemagglutinin.

4 binding domains of the viral surface protein haemagglutinin.

5 etion mutation in fhaB, encoding filamentous haemagglutinin.

6 oorly immunogenic and doses of 7.5-30 microg haemagglutinin alone are unlikely to give protection fro

7 One member of this family, the Dr haemagglutinin, also binds to a second receptor, type IV

8 eins of 37-43 residues that target influenza haemagglutinin and botulinum neurotoxin B, along with 6,

9 on-replicating, adenovirus vector expressing haemagglutinin and double-stranded RNA adjuvant delivere

10 t differs from the bundles described for the haemagglutinin and HIV/SIV gp41 membrane-fusion proteins

11 t of antigen localization, as membrane-bound haemagglutinin and I-Ealpha are also not presented by MH

12 egulatory regions of the virus, and chimeric haemagglutinin and neuraminidase genes.

13 s, with the remaining two genes encoding the haemagglutinin and neuraminidase proteins of a prototypi

14 e as the six viral RNA segments not encoding haemagglutinin and neuraminidase) that support high yiel

15 B, the first two activities are mediated by haemagglutinin and the third by a second glycoprotein, n

16 cines stimulate neutralising antibody to the haemagglutinin antigen but as there is antigenic drift i

17 The Dr haemagglutinin binds type IV collagen and, unlike other

18 he sialic acid-binding domain of influenza A haemagglutinin, but binds 9-O-acetylsialic acid.

19 : this requires interactions of the BCR with haemagglutinin, causing both disruption of antibody secr

20 are associated with high virulence from the haemagglutinin cleavage site of A/Hong Kong/213/03 using

21 Influenza A virus haemagglutinin conformational change drives the membrane

22 A filamentous haemagglutinin-deficient mutant (BP353) and a clinical i

23 sis of intragroup variants comprising the Dr haemagglutinin (DraE) group revealed that the point muta

24 rmational rearrangement of newly synthesized haemagglutinin during transport to the cell surface by e

25 The haemagglutinin epitope tag was inserted at 23 amino acid

26 Linking amino acid substitutions in haemagglutinin epitopes to epidemiology has been problem

27 nfluenza C virus, a single glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, possesses

28 tem domain is similar to that of influenza A haemagglutinin, except that the triple-stranded, alpha-h

29 B. pertussis mutants lacking filamentous haemagglutinin (FHA) released significantly more AC toxi

30 osed and secreted protein called filamentous haemagglutinin (FHA) that functions in adherence and imm

31 One of its adhesins is filamentous haemagglutinin (FHA), a 500-A-long secreted protein that

32 ACT binds filamentous haemagglutinin (FHA), a surface-displayed adhesin, and u

33 Filamentous haemagglutinin (FHA), expressed by Bordetella species, i

34 ecretion of the virulence factor filamentous haemagglutinin (FHA).

35 accine candidate (Ad4-H5-Vtn) expressing the haemagglutinin from an avian influenza A H5N1 virus.

36 an adjuvant during vaccination of mice with haemagglutinin from the influenza virus, the particles e

37 dy conducted in pigs, describing part of the haemagglutinin gene (HA1) of an influenza virus, we find

38 en nucleotides at different positions in the haemagglutinin gene, allowing for the analysis of popula

39 certain packaging signals, most notably the haemagglutinin gene; this finding has major implications

40 , viruses were produced containing the viral haemagglutinin (HA) and neuraminidase (NA) genes of the

41 criptional regulation of one specific vsp, a haemagglutinin (HA) epitope-tagged h7 was integrated int

42 ned by multi-colour flow cytometry for viral haemagglutinin (HA) expression and cell surface markers

43 ements of the receptor-binding properties of haemagglutinin (HA) from the transmissible mutant indica

44 n influenza virus, hundreds of copies of the haemagglutinin (HA) fusion glycoprotein project from the

45 t, although within-host genetic diversity in haemagglutinin (HA) increases during replication in inoc

46 Influenza haemagglutinin (HA) is responsible for fusing viral and

47 the resultant production of recombinant 1918 haemagglutinin (HA) protein antigen to characterize at t

48 ognize invariant structures on the influenza haemagglutinin (HA) protein have invigorated efforts to

49 The viral haemagglutinin (HA) protein is a known host-range determ

50 Here we report an haemagglutinin (HA) stem-directed bnAb, 3I14, isolated f

51 fection is mediated via binding of the viral haemagglutinin (HA) to terminally attached alpha2,3 or a

52 the receptor-binding site (RBS) of influenza haemagglutinin (HA) via a long CDR H3.

53 -anchored subunit HA2 of the influenza virus haemagglutinin (HA) was solubilized by adding the very p

54 utathione S-transferase (GST)-Rad23 and Rad4-haemagglutinin (HA), and the proteasome subunits Cim3 an

55 tallography of the receptor-binding protein, haemagglutinin (HA), in complex with receptor analogues

56 five identified antibody binding regions in haemagglutinin (HA).

57 ined the three-dimensional structures of the haemagglutinins (HAs) from H5 avian and H9 swine viruses

58 cles(4) carrying wild-type haemagglutinin or haemagglutinin hemifusion mutant G1S(5) and liposome mix

59 Similarly, anti-haemagglutinin immunoprecipitates from lysates of normox

60 Transferrin conjugated haemagglutinin induced a significant antibody and T cell

61 We propose that haemagglutinin induces a merger between the viral and ta

62 doses of 7.5 microg, 15 microg, or 30 microg haemagglutinin influenza A H9N2 vaccine, were given 3 we

63 , manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in

64 gainst influenza B viruses belonging to both haemagglutinin lineages and spanning over 70 years of an

65 an endosome activates the M2 channel before haemagglutinin-mediated fusion.

66 related Type IV pili, the mannose-sensitive haemagglutinin (MSHA) pilus, which aids V. cholerae pers

67 Antibodies elicited by a 1999 haemagglutinin-nanoparticle vaccine neutralized H1N1 vir

68 H10 we have determined the structure of the haemagglutinin of a previously isolated avian H10 virus

69 harbour B cells with a BCR specific for the haemagglutinin of influenza A/WSN/33 virus (FluBI mice).

70 protective monoclonal antibodies against the haemagglutinin of influenza B viruses have been describe

71 a virus-like particles(4) carrying wild-type haemagglutinin or haemagglutinin hemifusion mutant G1S(5

72 tinin per H3N2 vaccine strain, and 15 mug of haemagglutinin per B vaccine strain) (1) by microneedle

73 vated influenza vaccine (fluvirin: 18 mug of haemagglutinin per H1N1 vaccine strain, 17 mug of haemag

74 gglutinin per H1N1 vaccine strain, 17 mug of haemagglutinin per H3N2 vaccine strain, and 15 mug of ha

75 random mutations in the globular head of the haemagglutinin protein (which includes the antigenic sit

76 Recognition of the haemagglutinin receptor-binding site is dominated by a s

77 2 viruses, on the basis of analyses of 9,604 haemagglutinin sequences of human seasonal influenza vir

78 outcome of interactions between an influenza haemagglutinin-specific B cell via its receptor (BCR) an

79 c acids, the A/WSN/33 virus infects only the haemagglutinin-specific B cells.

80 tural data demonstrate that they bind to the haemagglutinin stem through conserved heavy-chain comple

81 tibodies that target a conserved site in the haemagglutinin stem.

82 ntibodies to two highly conserved vulnerable haemagglutinin structures that are targets of universal

83 -incompetent, human adenoviral-vector-based, haemagglutinin subtype 5 influenza vaccine (HAd-H5HA), w

84 charged amino-acid at position 54 of the Dr haemagglutinin subunit for chloramphenicol sensitivity o

85 elements of the receptor-binding site on the haemagglutinin surface glycoprotein.

86 nity by accumulating antigenic change in the haemagglutinin surface protein.

87 iven 3 weeks apart, of 7.5, 15, or 30 microg haemagglutinin surface-antigen influenza A H5N3 vaccine.

88 Haemagglutinin-tagged ANO4 was localised to the plasma m

89 Here we developed Flag- and haemagglutinin-tagged cyclin D1 knock-in mouse strains t

90 PC3M cells that had been co-transfected with haemagglutinin-tagged HIF-1alpha and wild-type p53 also

91 A haemagglutinin-tagged version of this patatin-like prote

92 a strategy to identify amino acids in the Dr haemagglutinin that are specifically involved in the int

93 ions in the receptor-binding site of the H10 haemagglutinin that decrease its avidity for avian recep

94 Here we develop a fitness model for haemagglutinin that predicts the evolution of the viral

95 We tested whether conjugating influenza haemagglutinin to transferrin could improve the immune r

96 racellular polysaccharide, mannose-sensitive haemagglutinin type 4 pili and polar (but not lateral) f

97 e surface itself activates mannose-sensitive haemagglutinin type IV pilus (MSHA)-mediated attachment,

98 hesis and secretion of the mannose-sensitive haemagglutinin type IV pilus (MSHA); (ii) the synthesis

99 The viral haemagglutinin was genetically fused to ferritin, a prot

100 Haemagglutinin was inserted at the interface of adjacent

101 antibodies that bind to the globular head of haemagglutinin, which undergoes a continuous antigenic d

102 structure of the complex formed by avian H10 haemagglutinin with human receptor, it is clear that the

103 lent amounts of virus through interaction of haemagglutinin with surface-disposed sialic acids, the A