ライフサイエンスコーパス: hair growth

1 ation, melanocyte development and apoptosis, hair growth).

2 , and cellular development (for example root hair growth).

3 ding of the complex network governing cyclic hair growth.

4 ing certain phases of normal or pathological hair growth.

5 e active phase), thereby facilitating robust hair growth.

6 neurogenic skin inflammation, which inhibits hair growth.

7 med calcium spiking) and alterations in root hair growth.

8 o Peronospora parasitica infection, and root hair growth.

9 pheomelanogenesis and eumelanogenesis during hair growth.

10 tion of TAT-Cre recombinase failed to affect hair growth.

11 reduced inflammatory response and increased hair growth.

12 plays a critical role in the maintenance of hair growth.

13 AtSfh1 activity in supporting polarized root hair growth.

14 n and cytoprotection to appetite control and hair growth.

15 rate the dermal papilla, a key component for hair growth.

16 novers and five cycles of depilation-induced hair growth.

17 been used to address the cyclical nature of hair growth.

18 morpha rhizoid and Arabidopsis thaliana root hair growth.

19 act in the same pathway in the regulation of hair growth.

20 follicle cycle, with concomitant accelerated hair growth.

21 of mice, and have investigated their role in hair growth.

22 ir follicles to enter anagen with consequent hair growth.

23 oisomer, 17-alpha-estradiol, did not inhibit hair growth.

24 telogen and enter anagen, thereby initiating hair growth.

25 re may have therapeutic potential to promote hair growth.

26 ablishment and maintenance of polarized root hair growth.

27 ify genes regulated by RSL4 that affect root hair growth.

28 in inflamed tissues, skin sensitization, and hair growth.

29 ges in root length, root branching, and root hair growth.

30 aling promoted adipocyte differentiation and hair growth.

31 ial therapeutic targets for modulating human hair growth.

32 ities to fine tune Wnt signaling for desired hair growth.

33 transit-amplifying cells (TAC) that maintain hair growth.

34 B to activate Shh in matrix cells to sustain hair growth.

35 me mobilized to fuel tissue regeneration and hair growth.

36 sm to restore both DP cell number and normal hair growth.

37 he population dynamics resulting in rhythmic hair growth.

38 hh signaling contributes to DP formation and hair growth.

39 otheses about the impact of interventions on hair growth.

40 s the role of the inner root sheath in human hair growth.

41 tle is known of their functions in postnatal hair growth.

42 ar structure of root hairs, and reduces root hair growth.

43 PS, used as a control, had no effect on root hair growth.

44 ling pathway with an essential role in human hair growth.

45 n Arabidopsis resulted in inhibition of root hair growth.

46 major effect of altered lipid metabolism on hair growth.

47 rther suggest a crucial role of LIPH gene in hair growth.

48 s an important role in the control of normal hair growth.

49 (RSL4) is necessary and sufficient for root hair growth(2).

50 ssion of these constructs results in stunted hair growth, a phenotype that has also been observed in

51 important implications toward restoration of hair growth after injury, disease, and aging.

52 % of Epi-Insig-DKO mice exhibited defects in hair growth along with other skin abnormalities, includi

53 e results support the hypothesis that murine hair growth and attendant melanogenesis can be regulated

54 as associated with a marked decrease in root hair growth and curling.

55 nd matrix cells may play roles in regulating hair growth and cycling.

56 ucidate a molecular mechanism that regulates hair growth and development, particularly in controlling

57 esults suggest that lipase H participates in hair growth and development.

58 length, suggesting a role for AGC2-1 in root hair growth and development.

59 g molecular mechanisms of Hoxc13 function in hair growth and development.

60 eatment, the hydrogel scaffolds promoted new hair growth and epidermal morphology and thickness simil

61 ras(G12D)) in the skin had strong effects on hair growth and hair shape, steady state changes in down

62 t improved follicle vascularization promotes hair growth and increases hair follicle and hair size.

63 e role of Bcl-2 expression in the control of hair growth and keratinocyte apoptosis, we have used tra

64 ure of the epidermis that is responsible for hair growth and lubrication of the epithelium.

65 microtubule cytoskeleton is involved in root hair growth and orientation, we applied microtubule anta

66 ies of hair matrix progenitors that regulate hair growth and pigmentation, partly by creating an SCF-

67 The molecular mechanisms controlling human hair growth and scalp hair loss are poorly understood.

68 zed role for WNT signaling in the control of hair growth and structure, as well as presenting the fir

69 t be guided largely by patient distress with hair growth and subjective perceptions as opposed to cli

70 including the dermal papilla that regulates hair growth and the arrector pili muscle, which controls

71 ose their stem cell potency to contribute to hair growth and undergo premature differentiation instea

72 ated from tissue prior to, during, and after hair growth and used to probe Affymetrix Drosophila gene

73 or Mpzl3 in the control of skin development, hair growth, and adipose cell functions.

74 vulgaris, acne scars, skin rejuvenation and hair growth, and for therapeutic applications including

75 decreased body mass, lordokyphosis, reduced hair growth, and generalized fat, muscle and organ atrop

76 ollicular dermal papilla is known to control hair growth, and steroid hormones regulate receptor and

77 immunosuppressive therapy display excessive hair growth, and unveil a functional role for calcium-NF

78 l labyrinth morphology, lung lobe septation, hair growth, and vascularization of kidney glomeruli.

79 results in impaired epidermal proliferation, hair growth, and wound healing.

80 as undetectable in telogen, increased during hair growth, and, after reaching the highest values in a

81 characterize the biological role of VEGF for hair growth, angiogenesis, and follicle cycling.

82 the mechanisms by which they regulate human hair growth are still poorly understood.

83 reservoir of epidermal stem cells, promoting hair growth, as well as stimulating tissue repair after

84 In vivo hair growth assays showed that GFP-positive cells could

85 c acid has long been known to alter skin and hair growth but an exact mechanism is unclear.

86 root hair tip is not only essential for root hair growth, but also dependent on the cytoplasmic calci

87 within the hair follicle maintain the cyclic hair growth, but whether these stem cells also contribut

88 Wild-type cells are co-opted into new hair growths by beta-catenin mutant cells, which non-cel

89 m, corresponding to approximately 10 days of hair growth, by using a high spatial resolution exit con

90 Hh-agonist-induced hair growth caused no detectable differences in epiderma

91 sing in vivo imaging we found that, early in hair growth, cells have multiple actin bundles and hairs

92 te factors that are expressed or lost during hair growth cessation.

93 minoxidil and that tolbutamide may suppress hair growth clinically; novel drugs designed specificall

94 of Krox20 lineage cells results in arrest of hair growth, confirming the critical role of KROX20(+) c

95 crine and/or autocrine functions, such as in hair growth control.

96 Most strategies to enhance Wnt signaling for hair growth create a state of constitutive Wnt activatio

97 licular location even upon completion of the hair growth cycle 21 d later.

98 jagged 1 (Jag1) results in inhibition of the hair growth cycle and conversion of hair follicles into

99 sting hair follicles were recruited into the hair growth cycle and epithelial outgrowths formed from

100 ical; however, the factors that regulate the hair growth cycle are still poorly understood.

101 adverse effect may produce insights into the hair growth cycle as well as potential therapeutic targe

102 The hair growth cycle is generally recognized to comprise ph

103 ave made use of the fact that in rodents the hair growth cycle is synchronized, well characterized, a

104 pression in the bulge was independent of the hair growth cycle stage.

105 was delivered during different stages of the hair growth cycle, followed by histologic and gross obse

106 eted by adipocytes are known to regulate the hair growth cycle, it is unclear whether the epidermis c

107 In the telogen phase of the hair growth cycle, PAI-2 was limited to the postmitotic

108 ts in the follicle outer-root sheath and the hair growth cycle, respectively, the hair defect in the

109 ent increased hair survival during the first hair growth cycle, the level of protection having a slig

110 elanocytes in epidermis to UV nonresponsive, hair growth cycle-coupled melanogenesis in hair follicle

111 ilaggrin-negative matrix cells and displayed hair growth cycle-dependent expression.

112 cation and differentiation status during the hair growth cycle.

113 a4 in a highly coordinated manner during the hair growth cycle.

114 rent stages of the depilation-induced murine hair growth cycle.

115 observed in conjunction with changes in the hair growth cycle.

116 expression at different stages of the human hair growth cycle.

117 icles are in the anagen stage of their first hair growth cycle.

118 o function as mediators or regulators of the hair growth cycle.

119 the follicle during the anagen phase of the hair growth cycle.

120 plies a regulatory role for IGF-I during the hair growth cycle.

121 hronizing adipocyte differentiation with the hair growth cycle.

122 al proliferation and differentiation and the hair growth cycle.

123 l and spatial expression patterns during the hair-growth cycle by quantitative real-time PCR and in s

124 icroarray dataset of mRNA expression for the hair-growth cycle in mouse back skin, predicting both pr

125 The hair-growth cycle is an example of a cyclic process that

126 ls may provide a mechanism through which the hair-growth cycle is regulated by cell survival.

127 t many more genes may be associated with the hair-growth cycle than have been identified in the liter

128 The hair-growth cycle, a complex biological system requiring

129 in that are associated specifically with the hair-growth cycle.

130 transcription factor in the midphase of the hair-growth cycle.

131 nt, using a model of predictable synchronous hair growth cycles in the infantile and adolescent mice.

132 are not significantly depleted by successive hair growth cycles.

133 atonin has been experimentally implicated in hair growth cycling, pigmentation physiology, and melano

134 ho show an inherited form of hair loss and a hair growth defect.

135 known as GC13 mice), known to develop severe hair growth defects and alopecia, as a tool for defining

136 aging and pharmacologic modification of root hair growth defects in rhd3 suggest that there is interp

137 The severe hair growth defects observed upon aberrant expression of

138 Hair growth defects of homozygous toku mice were partial

139 riants, but not ACT7, fully rescued the root hair growth defects of single and double mutants.

140 d to elevated lipid synthesis and subsequent hair growth defects.

141 y mice showed almost complete restoration of hair growth, dermal ridges, sweat glands and molars.

142 e of vitamin D receptor in the regulation of hair growth directly, we used the human keratin 14 promo

143 y provide useful therapeutic tools for human hair growth disorders based on premature or retarded cat

144 agonists may be useful for the management of hair growth disorders characterized by premature entry i

145 e underlying principles of hair development, hair growth disorders, and skin cancers.

146 HF cycling abnormalities underlie many human hair growth disorders, the accurate classification of in

147 In addition, hair growth from grafted wrfr skin is impaired.

148 often ensue, such as strictures, infection, hair growth, graft shrinkage, diverticuli, and even mali

149 psychoemotional stress can have an impact on hair growth has been treated with skepticism and assigne

150 veral processes, including limb development, hair growth, hearing and gametogenesis.

151 y RHD2/AtrbohC NADPH oxidase is required for hair growth; here we show that SCN1/AtrhoGDI1 is a compo

152 ors involved in wound healing and regulating hair growth; however, their role in skin regeneration af

153 scoring method assessing androgen-dependent hair growth in 9 body areas.

154 ifluoromethylornithine could also reactivate hair growth in animals with complete hair loss.

155 into the cytoplasm that is required for root hair growth in Arabidopsis thaliana.

156 ve identified FGF5 as a crucial regulator of hair growth in humans for the first time, to our knowled

157 leted rat cortical neurons and impaired root hair growth in loss-of-function mutants of the ATL1 orth

158 re, we report that thymosin beta4 stimulates hair growth in normal rats and mice.

159 owed marked acceleration of the onset of new hair growth in the region of AdShh administration to ski

160 the PPR in the hair cycle, we have evaluated hair growth in the traditional K14-PTHrP (KrP) and an in

161 ture has been established for some time, but hair growth in vitro is limited and generally terminates

162 ha and IL-1 beta are important inhibitors of hair growth in vitro.

163 ose their HF-inducing properties, but during hair growth in vivo, they reside within the HF bulb and

164 Thus, thymosin beta4 accelerates hair growth, in part, due to its effect on critical even

165 During hair growth, increase in total follicular papilla size w

166 a-Catenin activation is sufficient to induce hair growth independently of mesenchymal dermal papilla

167 otection was maintained during two cycles of hair growth indicated that the clonogenic cells had been

168 ation of a specific COX-2 inhibitor restored hair growth, indicating that the alopecia was attributab

169 As a hair growth inducer, noggin increases Shh mRNA in the HF

170 ase induction in postnatal skin and that the hair growth-inducing effect of noggin is mediated, at le

171 preactivation reduced premature catagen and hair growth inhibition induced by oxidative stress (H2O2

172 Hair growth is associated with pronounced vascular-endot

173 In mammals hair growth is cyclical; however, the factors that regul

174 These data confirm that the cessation in hair growth is not due to a loss of the inductive capaci

175 ing high levels of E2F1, mice have decreased hair growth likely as a result of aberrant apoptosis in

176 ponses to pathogen infection and normal root hair growth, linking defense response regulation with th

177 cyclical and initially synchronous nature of hair growth makes the hair follicle an ideal system with

178 testing may facilitate testing of candidate hair growth modulatory agents in human HF organ culture

179 During hair growth Mwh is found in growing hairs, where we sugg

180 As stem cells become activated during hair growth, NFATc1 is downregulated, relieving CDK4 rep

181 Tanner stage 5 for pubic hair growth occurred 6-9 months later on average for boy

182 r genitalia growth, Tanner stage 5 for pubic hair growth, or testicular volume (TV) >/= 20 mL in eith

183 intervention modalities in distinct skin and hair growth pathologies.

184 s, including increased body weight, abnormal hair growth pattern, lymphoma, mammary tumors, and endom

185 We also reviewed early accounts of "hair growth patterns" from classical literature.

186 ction in embryonic skin, initiation of a new hair growth phase in postnatal skin requires neutralizat

187 administration of noggin protein induces new hair growth phase in postnatal telogen skin in vivo.

188 of BMP4 signaling by noggin is essential for hair growth phase induction in postnatal skin and that t

189 ws that MadB1-4 contribute to polarized root hair growth, phenocopying myosins, whereas MadA1-4 are r

190 y be the long-sought 'chalone' inhibitors of hair growth postulated by classical experiments.

191 e follicular epithelial cells to prolong the hair growth process.

192 f the agouti signaling protein (ASIP) during hair growth produces the red/yellow pigment pheomelanin.

193 d phenotype toku is characterized by delayed hair growth, progressive hair loss, and excessive accumu

194 lysis, are less useful due to differences in hair growth rate between individual hairs.

195 cells, which do not normally participate in hair growth, re-populate the lost stem-cell compartment

196 e as well as the apical localization of root hair growth regulator ROP2 is oscillated in rhd3 Interes

197 DPCs secreted higher levels of the negative hair growth regulators transforming growth factor beta 1

198 onic hair follicle development and postnatal hair growth rely on intercellular communication within t

199 egulate hair follicle progenitors to control hair growth remains unclear.

200 In plants, root hair growth requires polar nuclear migration into the ou

201 es in both mouse and man suggest that proper hair growth requires their spatio-temporally coordinated

202 ng this pulse is modulated as part of a root hair growth response to low phosphate.

203 ith a neutralizing anti-VEGF antibody led to hair growth retardation and reduced hair follicle size.

204 mutant, which is defective in sustained root hair growth, showed an altered [Ca2+]c distribution comp

205 erties and home back to the bulge niche when hair growth stops.

206 ely related dermal fibroblasts, can maintain hair growth suggesting cell type-specific molecular sign

207 our data identify Sox2 as a key regulator of hair growth that controls progenitor migration by fine-t

208 We find that the DKO mice have a defect in hair growth that is markedly worse than that of SGK3(-/-

209 ur understanding of the regulation of normal hair growth, the basis of hereditary hair loss diseases,

210 s, e.g., minoxidil and diazoxide, can induce hair growth, their mechanisms require clarification.

211 mouse hair follicle stem cells generates new hair growth through oriented cell divisions and cellular

212 cells and their progeny to fuel and maintain hair growth throughout the life of an organism.

213 ynamic adipogenic program that occurs during hair growth to uncover an unrecognized regulator of ASC

214 These transgenic mice have delayed hair growth, underdeveloped ears, and shorter tails.

215 Here, we explore why hair growth wanes with age.

216 Similar defective hair growth was observed in kinase-inactive GK5 mutant m

217 aBK allele, somatic, testicular, genital and hair growth were grossly affected and influenced by the

218 Moreover, isolated dermal tissue induced hair growth when implanted into inactivated hair follicl

219 retards anagen entry and consequently delays hair growth, whereas loss of Msi2 enhances hair regrowth

220 duced a profound and prolonged inhibition of hair growth while treatment with the biologically inacti

221 efects were found in HAT-L4 knockout mice in hair growth, wound healing, water repulsion and body tem